Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

M. Vendruscolo · SciRah

Researcher profile · Semantic Scholar

M. Vendruscolo

Share profile

M. Vendruscolo — researcher profile on SciRah

h-index: 115
Works: 678
Citations: 56K

Most-cited papers

The Amyloid-β Pathway in Alzheimer’s Disease
H. Hampel, John Hardy, Kaj Blennow, Christopher Chen +11 more
2021Molecular Psychiatry1,755 citations Open access
Semantic Scholar
Small soluble α-synuclein aggregates are the toxic species in Parkinson’s disease
D. Emin, Yu P. Zhang, Evgeniia Lobanova, Alyssa Miller +15 more
2022Nature Communications190 citations Open access
Semantic Scholar
Amyloid formation as a protein phase transition
T. Michaels, Daoyuan Qian, A. Šarić, M. Vendruscolo +2 more
2023Nature Reviews Physics155 citations
Semantic Scholar
FuzDrop on AlphaFold: visualizing the sequence-dependent propensity of liquid–liquid phase separation and aggregation of proteins
András Hatos, S. Tosatto, M. Vendruscolo, M. Fuxreiter
2022Nucleic Acids Res.143 citations Open access
Semantic Scholar
Generic nature of the condensed states of proteins
M. Fuxreiter, M. Vendruscolo
2021Nature Cell Biology126 citations
Semantic Scholar
AlphaFold prediction of structural ensembles of disordered proteins
Z. F. Brotzakis, Sheng-Yu Zhang, M. Murtada, M. Vendruscolo
2023bioRxiv125 citations Open access
Semantic Scholar
Protein condensation diseases: therapeutic opportunities
M. Vendruscolo, M. Fuxreiter
2022Nature Communications107 citations Open access
Semantic Scholar
The docking of synaptic vesicles on the presynaptic membrane induced by α-synuclein is modulated by lipid composition
Wing K. Man, Bogachan Tahirbegi, Michail D. Vrettas, Swapan Preet +4 more
2021Nature Communications103 citations Open access
Semantic Scholar
Quantifying misfolded protein oligomers as drug targets and biomarkers in Alzheimer and Parkinson diseases
K. Kulenkampff, Adriana-Michelle Wolf Pérez, Pietro Sormanni, J. Habchi +1 more
2021Nature Reviews Chemistry96 citations
Semantic Scholar
Aβ Oligomers Dysregulate Calcium Homeostasis by Mechanosensitive Activation of AMPA and NMDA Receptors
Giulia Fani, B. Mannini, Giulia Vecchi, R. Cascella +4 more
2021ACS Chemical Neuroscience86 citations Open access
Semantic Scholar
Spontaneous nucleation and fast aggregate-dependent proliferation of α-synuclein aggregates within liquid condensates at neutral pH
Samuel T Dada, M. Hardenberg, Z. Toprakcioglu, Lena K Mrugalla +6 more
2023Proceedings of the National Academy of Sciences of the United States of America85 citations Open access
Semantic Scholar
Cytosolic aggregation of mitochondrial proteins disrupts cellular homeostasis by stimulating the aggregation of other proteins
U. Nowicka, P. Chrościcki, K. Stroobants, Maria Sladowska +8 more
2021bioRxiv83 citations Open access
Semantic Scholar
The Hsc70 disaggregation machinery removes monomer units directly from α-synuclein fibril ends
Matthias M. Schneider, Saurabh Gautam, T. Herling, E. Andrzejewska +10 more
2021Nature Communications77 citations Open access
Semantic Scholar
Soluble amyloid beta-containing aggregates are present throughout the brain at early stages of Alzheimer’s disease
Dimitrios I Sideris, J. Danial, D. Emin, F. Ruggeri +12 more
2021Brain Communications69 citations Open access
Semantic Scholar
Proliferation of Tau 304–380 Fragment Aggregates through Autocatalytic Secondary Nucleation
D. C. Rodriguez Camargo, Eimantas Šileikis, Sean Chia, Emil Axell +8 more
2021ACS Chemical Neuroscience62 citations Open access
Semantic Scholar
α-Synuclein oligomers form by secondary nucleation
Catherine K. Xu, G. Meisl, E. Andrzejewska, G. Krainer +11 more
2024bioRxiv61 citations Open access
Semantic Scholar
Extracellular protein homeostasis in neurodegenerative diseases
M. Wilson, S. Satapathy, M. Vendruscolo
2023Nature Reviews Neurology56 citations
Semantic Scholar
Fragment-based computational design of antibodies targeting structured epitopes
Mauricio Aguilar Rangel, A. Bedwell, E. Costanzi, Ross J Taylor +6 more
2022bioRxiv55 citations Open access
Semantic Scholar
A Small Molecule Stabilizes the Disordered Native State of the Alzheimer’s Aβ Peptide
T. Löhr, Kai J. Kohlhoff, Gabriella T. Heller, C. Camilloni +1 more
2022ACS Chemical Neuroscience50 citations Open access
Semantic Scholar
Discovery of potent inhibitors of α-synuclein aggregation using structure-based iterative learning
Robert I. Horne, Ewa A. Andrzejewska, P. Alam, Z. F. Brotzakis +12 more
2021bioRxiv49 citations Open access
Semantic Scholar
ATP-competitive inhibitors modulate the substrate binding cooperativity of a kinase by altering its conformational entropy
C. Olivieri, Geoffrey C. Li, Yingjie Wang, Manu V. S. +8 more
2022Science Advances46 citations Open access
Semantic Scholar
Sequence-based prediction of pH-dependent protein solubility using CamSol
Marc Oeller, Ryan J D Kang, Rosie Bell, Hannes Ausserwöger +2 more
2023Briefings Bioinform.45 citations Open access
Semantic Scholar
CAID prediction portal: a comprehensive service for predicting intrinsic disorder and binding regions in proteins
Alessio Del Conte, Adel Bouhraoua, M. Mehdiabadi, Damiano Clementel +59 more
2023Nucleic Acids Res.44 citations Open access
Semantic Scholar
Amyloidogenic proteins in the SARS-CoV and SARS-CoV-2 proteomes
Taniya Bhardwaj, K. Gadhave, S. K. Kapuganti, Prateek Kumar +11 more
2023Nature Communications43 citations Open access
Semantic Scholar
Characterization of Pairs of Toxic and Nontoxic Misfolded Protein Oligomers Elucidates the Structural Determinants of Oligomer Toxicity in Protein Misfolding Diseases
Ryan Limbocker, N. Cremades, R. Cascella, Peter M. Tessier +2 more
2023Accounts of Chemical Research42 citations Open access
Semantic Scholar
N-Terminal Acetylation of α-Synuclein Slows down Its Aggregation Process and Alters the Morphology of the Resulting Aggregates
Rosie Bell, Rebecca J. Thrush, Marta Castellana-Cruz, Marc Oeller +10 more
2022Biochemistry41 citations Open access
Semantic Scholar
Modulation of the Interactions Between α-Synuclein and Lipid Membranes by Post-translational Modifications
Rosie Bell, M. Vendruscolo
2021Frontiers in Neurology40 citations Open access
Semantic Scholar
Adsorption free energy predicts amyloid protein nucleation rates
Z. Toprakcioglu, Ayaka Kamada, T. Michaels, Mengqi Xie +5 more
2022Proceedings of the National Academy of Sciences of the United States of America39 citations Open access
Semantic Scholar
Squalamine and trodusquemine: two natural products for neurodegenerative diseases, from physical chemistry to the clinic.
Ryan Limbocker, Silvia Errico, D. Barbut, T. Knowles +3 more
2021Natural product reports (Print)39 citations Open access
Semantic Scholar
Assessment of Therapeutic Antibody Developability by Combinations of In Vitro and In Silico Methods.
Adriana-Michelle Wolf Pérez, Nikolai Lorenzen, M. Vendruscolo, Pietro Sormanni
2021Methods in molecular biology38 citations
Semantic Scholar
Correlation between the binding affinity and the conformational entropy of nanobody SARS-CoV-2 spike protein complexes
H. Mikolajek, M. Weckener, Z. F. Brotzakis, J. Huo +16 more
2022Proceedings of the National Academy of Sciences of the United States of America37 citations Open access
Semantic Scholar
Towards sequence-based principles for protein phase separation predictions.
M. Vendruscolo, M. Fuxreiter
2023Current Opinion in Chemical Biology36 citations Open access
Semantic Scholar
Lipid Homeostasis and Its Links With Protein Misfolding Diseases
M. Vendruscolo
2022Frontiers in Molecular Neuroscience32 citations Open access
Semantic Scholar
The amyloid-β pathway in Alzheimer's disease: a plain language summary
Harald Hampel, Yan Hu, John Hardy, K. Blennow +12 more
2023Neurodegenerative Disease Management29 citations Open access
Semantic Scholar
Misfolded protein oligomers induce an increase of intracellular Ca2+ causing an escalation of reactive oxidative species
Giulia Fani, Chiara Ester La Torre, R. Cascella, C. Cecchi +2 more
2022Cellular and Molecular Life Sciences27 citations Open access
Semantic Scholar
Effects of N-terminal acetylation on the aggregation of disease-related α-synuclein variants.
Rosie Bell, Marta Castellana-Cruz, Aishwarya Nene, Rebecca J. Thrush +3 more
2022Journal of Molecular Biology27 citations Open access
Semantic Scholar
Multiplexed Digital Characterization of Misfolded Protein Oligomers via Solid-State Nanopores
Sarah E. Sandler, Robert I. Horne, Sara Rocchetti, Robert Novak +8 more
2023Journal of the American Chemical Society25 citations Open access
Semantic Scholar
Determination of the Structure and Dynamics of the Fuzzy Coat of an Amyloid Fibril of IAPP Using Cryo-Electron Microscopy
Z. F. Brotzakis, T. Löhr, Steven D. Truong, Samuel E. Hoff +2 more
2022bioRxiv25 citations Open access
Semantic Scholar
Kinetic profiling of therapeutic strategies for inhibiting the formation of amyloid oligomers.
T. Michaels, A. Dear, Samuel I. A. Cohen, M. Vendruscolo +1 more
2022Journal of Chemical Physics24 citations Open access
Semantic Scholar
Comparative Studies in the A30P and A53T α-Synuclein C. elegans Strains to Investigate the Molecular Origins of Parkinson's Disease
Michele Perni, A. T. van der Goot, Ryan Limbocker, T. V. van Ham +25 more
2021Frontiers in Cell and Developmental Biology24 citations Open access
Semantic Scholar
An open-source automated PEG precipitation assay to measure the relative solubility of proteins with low material requirement
Marc Oeller, Pietro Sormanni, M. Vendruscolo
2021Scientific Reports24 citations Open access
Semantic Scholar
Multiomic prediction of therapeutic targets for human diseases associated with protein phase separation
Christine M. Lim, Alicia González Díaz, Monika Fuxreiter, Frank W. Pun +2 more
2023Proceedings of the National Academy of Sciences of the United States of America23 citations Open access
Semantic Scholar
FuzPred: a web server for the sequence-based prediction of the context-dependent binding modes of proteins
András Hatos, João M. C. Teixeira, S. Barrera-Vilarmau, Attila Horvath +3 more
2023Nucleic Acids Res.21 citations Open access
Semantic Scholar
The binding of the small heat-shock protein αB-crystallin to fibrils of α-synuclein is driven by entropic forces
T. Scheidt, J. Carozza, C. Kolbe, F. Aprile +12 more
2021Proceedings of the National Academy of Sciences of the United States of America21 citations Open access
Semantic Scholar
Secondary Processes Dominate the Quiescent, Spontaneous Aggregation of α-Synuclein at Physiological pH with Sodium Salts
Robert I. Horne, Michael A. Metrick, Wing K. Man, Dillon J. Rinauro +4 more
2023ACS Chemical Neuroscience20 citations Open access
Semantic Scholar
Neuroserpin and transthyretin are extracellular chaperones that preferentially inhibit amyloid formation
J. West, S. Satapathy, Daniel R. Whiten, M. Kelly +7 more
2021Science Advances19 citations Open access
Semantic Scholar
A maximum caliber approach for continuum path ensembles
P. Bolhuis, Z. F. Brotzakis, M. Vendruscolo
2021European Physical Journal B : Condensed Matter Physics19 citations Open access
Semantic Scholar
Quantitative Measurement of the Affinity of Toxic and Nontoxic Misfolded Protein Oligomers for Lipid Bilayers and of its Modulation by Lipid Composition and Trodusquemine
Silvia Errico, H. Ramshini, C. Capitini, C. Canale +7 more
2021ACS Chemical Neuroscience19 citations Open access
Semantic Scholar
Exploration and Exploitation Approaches Based on Generative Machine Learning to Identify Potent Small Molecule Inhibitors of α-Synuclein Secondary Nucleation
Robert I. Horne, M. Murtada, D. Huo, Z. F. Brotzakis +4 more
2023Journal of Chemical Theory and Computation18 citations Open access
Semantic Scholar
Multidimensional Protein Solubility Optimization with an Ultrahigh-Throughput Microfluidic Platform
Nadia A. Erkamp, Marc Oeller, Tomas Šneideris, Hannes Ausserwoger +9 more
2022bioRxiv18 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

T. Knowles×12
Invite
T. Knowles — researcher profile on SciRah
Z. F. Brotzakis×9
Invite
Z. F. Brotzakis — researcher profile on SciRah
Pietro Sormanni×8
Invite
Pietro Sormanni — researcher profile on SciRah
C. Dobson×6
Invite
C. Dobson — researcher profile on SciRah

×5

Invite

M. Fuxreiter — researcher profile on SciRah

Invite

F. Chiti — researcher profile on SciRah

Invite

Sean Chia — researcher profile on SciRah

Invite

T. Michaels — researcher profile on SciRah

Invite

G. Meisl — researcher profile on SciRah

Catherine K. Xu×4

Invite

Catherine K. Xu — researcher profile on SciRah

Robert I. Horne×4

Invite

Robert I. Horne — researcher profile on SciRah

Invite

Marc Oeller — researcher profile on SciRah