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F. Ruggeri · SciRah

Researcher profile · Semantic Scholar

F. Ruggeri

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F. Ruggeri — researcher profile on SciRah

h-index: 42
Works: 100
Citations: 6,073

Most-cited papers

FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions
S. Qamar, Guozhen Wang, Suzanne J. Randle, F. Ruggeri +20 more
2018Cell853 citations Open access
Semantic Scholar
Infrared nanospectroscopy characterization of oligomeric and fibrillar aggregates during amyloid formation
F. Ruggeri, G. Longo, S. Faggiano, E. Lipiec +2 more
2015Nature Communications268 citations Open access
Semantic Scholar
Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms
S. De, David C Wirthensohn, Patrick Flagmeier, Craig D. Hughes +13 more
2019Nature Communications220 citations Open access
Semantic Scholar
Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes
J. Habchi, Sean Chia, Céline Galvagnion, T. Michaels +10 more
2018Nature Chemistry211 citations Open access
Semantic Scholar
Measurement of intrinsic properties of amyloid fibrils by the peak force QNM method.
J. Adamcik, C. Lara, I. Usov, J. Jeong +5 more
2012Nanoscale192 citations Open access
Semantic Scholar
Small soluble α-synuclein aggregates are the toxic species in Parkinson’s disease
D. Emin, Yu P. Zhang, Evgeniia Lobanova, Alyssa Miller +15 more
2022Nature Communications190 citations Open access
Semantic Scholar
The liquid-to-solid transition of FUS is promoted by the condensate surface
Yi Shen, An-Jong Chen, Wenyun Wang, Yi-Nan Shen +11 more
2023Proceedings of the National Academy of Sciences of the United States of America181 citations Open access
Semantic Scholar
The H50Q Mutation Enhances α-Synuclein Aggregation, Secretion, and Toxicity*
Ossama Khalaf, Bruno Fauvet, A. Oueslati, I. Dikiy +8 more
2014Journal of Biological Chemistry170 citations Open access
Semantic Scholar
Influence of the β-sheet content on the mechanical properties of aggregates during amyloid fibrillization.
F. Ruggeri, J. Adamcik, J. Jeong, H. Lashuel +2 more
2015Angewandte Chemie166 citations Open access
Semantic Scholar
Biomolecular condensates undergo a generic shear-mediated liquid-to-solid transition
Yi Shen, F. Ruggeri, D. Vigolo, Ayaka Kamada +6 more
2020bioRxiv157 citations Open access
Semantic Scholar
Small-molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer’s disease
Gabriella T. Heller, F. Aprile, T. Michaels, Ryan Limbocker +12 more
2019Science Advances147 citations Open access
Semantic Scholar
Nanoscale studies link amyloid maturity with polyglutamine diseases onset
F. Ruggeri, S. Vieweg, U. Cendrowska, G. Longo +3 more
2016Scientific Reports142 citations Open access
Semantic Scholar
Detecting nanoscale vibrations as signature of life
S. Kasas, F. Ruggeri, C. Benadiba, C. Maillard +4 more
2014Proceedings of the National Academy of Sciences of the United States of America141 citations Open access
Semantic Scholar
Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes
Ryan Limbocker, Sean Chia, F. Ruggeri, Michele Perni +21 more
2019Nature Communications139 citations Open access
Semantic Scholar
Atomic force microscopy for single molecule characterisation of protein aggregation
F. Ruggeri, Tomas Šneideris, M. Vendruscolo, T. Knowles
2019Archives of Biochemistry and Biophysics138 citations Open access
Semantic Scholar
Controlled self-assembly of plant proteins into high-performance multifunctional nanostructured films
Ayaka Kamada, M. Rodriguez-Garcia, F. Ruggeri, Yi Shen +2 more
2021Nature Communications132 citations Open access
Semantic Scholar
Single molecule secondary structure determination of proteins through infrared absorption nanospectroscopy
F. Ruggeri, B. Mannini, R. Schmid, M. Vendruscolo +1 more
2020Nature Communications128 citations Open access
Semantic Scholar
Nanoplasmonic mid-infrared biosensor for in vitro protein secondary structure detection
D. Etezadi, J. B. Warner, F. Ruggeri, G. Dietler +2 more
2017Light: Science & Applications124 citations Open access
Semantic Scholar
Determination of Polypeptide Conformation with Nanoscale Resolution in Water
G. Ramer, F. Ruggeri, A. Levin, T. Knowles +1 more
2018ACS Nano118 citations Open access
Semantic Scholar
Silk micrococoons for protein stabilisation and molecular encapsulation
U. Shimanovich, F. Ruggeri, E. De Genst, J. Adamcik +8 more
2017Nature Communications117 citations Open access
Semantic Scholar
Identification and nanomechanical characterization of the fundamental single-strand protofilaments of amyloid α-synuclein fibrils
F. Ruggeri, F. Benedetti, T. Knowles, H. Lashuel +2 more
2018Proceedings of the National Academy of Sciences of the United States of America98 citations Open access
Semantic Scholar
Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer’s disease progression
S. De, Daniel R. Whiten, F. Ruggeri, Craig D. Hughes +13 more
2019Acta Neuropathologica Communications89 citations Open access
Semantic Scholar
AFM-Based Single Molecule Techniques: Unraveling the Amyloid Pathogenic Species
F. Ruggeri, J. Habchi, A. Cerreta, G. Dietler
2016Current pharmaceutical design78 citations Open access
Semantic Scholar
The Hsc70 disaggregation machinery removes monomer units directly from α-synuclein fibril ends
Matthias M. Schneider, Saurabh Gautam, T. Herling, E. Andrzejewska +10 more
2021Nature Communications77 citations Open access
Semantic Scholar
Infrared nanospectroscopy reveals the molecular interaction fingerprint of an aggregation inhibitor with single Aβ42 oligomers
F. Ruggeri, J. Habchi, Sean Chia, Robert I. Horne +2 more
2021Nature Communications76 citations Open access
Semantic Scholar
Transthyretin Inhibits Primary and Secondary Nucleations of Amyloid-β Peptide Aggregation and Reduces the Toxicity of Its Oligomers
Seyyed Abolghasem Ghadami, Sean Chia, F. Ruggeri, G. Meisl +7 more
2020Biomacromolecules74 citations Open access
Semantic Scholar
The Influence of Pathogenic Mutations in α-Synuclein on Biophysical and Structural Characteristics of Amyloid Fibrils.
F. Ruggeri, Patrick Flagmeier, J. Kumita, G. Meisl +4 more
2020ACS Nano71 citations Open access
Semantic Scholar
N-terminal Huntingtin (Htt) phosphorylation is a molecular switch regulating Htt aggregation, helical conformation, internalization, and nuclear targeting
Sean M. Deguire, F. Ruggeri, Mohamed Fares, A. Chiki +3 more
2018Journal of Biological Chemistry71 citations Open access
Semantic Scholar
Soluble amyloid beta-containing aggregates are present throughout the brain at early stages of Alzheimer’s disease
Dimitrios I Sideris, J. Danial, D. Emin, F. Ruggeri +12 more
2021Brain Communications69 citations Open access
Semantic Scholar
Microplastics and nanoplastics in food, water, and beverages, part II. Methods
Clementina Vitali, R. Peters, H. Janssen, M. Nielen +1 more
2022Trends in Analytical Chemistry (TrAC)67 citations Open access
Semantic Scholar
SUPPORTING INFORMATION Rational design of a conformation-specific antibody for the quantification of Ab oligomers
F. Aprile, Pietro Sormanni, Marina Podpolny, Shianne Chhangur +14 more
202066 citations
Semantic Scholar
Nanobodies raised against monomeric ɑ-synuclein inhibit fibril formation and destabilize toxic oligomeric species
Marija Iljina, Liu Hong, M. Horrocks, M. H. Ludtmann +14 more
2017BMC Biology66 citations Open access
Semantic Scholar
Mutant Exon1 Huntingtin Aggregation is Regulated by T3 Phosphorylation-Induced Structural Changes and Crosstalk between T3 Phosphorylation and Acetylation at K6.
A. Chiki, Sean M. Deguire, F. Ruggeri, D. Sanfelice +8 more
2017Angewandte Chemie65 citations Open access
Semantic Scholar
Identification of Oxidative Stress in Red Blood Cells with Nanoscale Chemical Resolution by Infrared Nanospectroscopy
F. Ruggeri, C. Marcott, S. Dinarelli, G. Longo +3 more
2018International Journal of Molecular Sciences63 citations Open access
Semantic Scholar
Ultrathin Polydopamine Films with Phospholipid Nanodiscs Containing a Glycophorin A Domain
Tommaso Marchesi D'Alvise, Sean Harvey, Lisa Hueske, Jolanta Szelwicka +12 more
2020Advanced Functional Materials58 citations Open access
Semantic Scholar
Imaging protein aggregates in the serum and cerebrospinal fluid in Parkinson’s disease
Evgeniia Lobanova, Daniel R. Whiten, F. Ruggeri, Christopher G. Taylor +7 more
2021Brain : a journal of neurology57 citations Open access
Semantic Scholar
Stabilization and Characterization of Cytotoxic Aβ40 Oligomers Isolated from an Aggregation Reaction in the Presence of Zinc Ions.
B. Mannini, J. Habchi, Sean Chia, F. Ruggeri +4 more
2018ACS Chemical Neuroscience56 citations Open access
Semantic Scholar
Nanoscale spatially resolved infrared spectra from single microdroplets.
Thomas Müller, F. Ruggeri, A. Kulik, U. Shimanovich +3 more
2014Lab on a Chip56 citations Open access
Semantic Scholar
Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism
Ryan Limbocker, B. Mannini, F. Ruggeri, R. Cascella +18 more
2020Communications Biology55 citations Open access
Semantic Scholar
Squalamine and Its Derivatives Modulate the Aggregation of Amyloid-β and α-Synuclein and Suppress the Toxicity of Their Oligomers
Ryan Limbocker, Roxine Staats, Sean Chia, F. Ruggeri +26 more
2021Frontiers in Neuroscience53 citations Open access
Semantic Scholar
One-pot semisynthesis of exon 1 of the Huntingtin protein: new tools for elucidating the role of posttranslational modifications in the pathogenesis of Huntington's disease.
A. Ansaloni, Zhe-Ming Wang, J. Jeong, F. Ruggeri +2 more
2014Angewandte Chemie48 citations Open access
Semantic Scholar
Microfluidic deposition for resolving single-molecule protein architecture and heterogeneity
F. Ruggeri, J. Charmet, T. Kartanas, Q. Peter +5 more
2018Nature Communications45 citations Open access
Semantic Scholar
A dopamine metabolite stabilizes neurotoxic amyloid-β oligomers
Rodrigo Cataldi, Sean Chia, Katarina Pisani, F. Ruggeri +12 more
2021Communications Biology44 citations Open access
Semantic Scholar
Water‐Dispersible Polydopamine‐Coated Nanofibers for Stimulation of Neuronal Growth and Adhesion
S. Sieste, T. Mack, C. Synatschke, Corinna Schilling +9 more
2018Advanced Healthcare Materials36 citations Open access
Semantic Scholar
A critical concentration of N-terminal pyroglutamylated amyloid beta drives the misfolding of Ab1-42 into more toxic aggregates.
D. Galante, F. Ruggeri, G. Dietler, F. Pellistri +5 more
2016International Journal of Biochemistry and Cell Biology36 citations Open access
Semantic Scholar
Molecular determinants of the interaction of EGCG with ordered and disordered proteins
Giuliana Fusco, Máximo Sanz-Hernández, F. Ruggeri, M. Vendruscolo +2 more
2018Biopolymers35 citations Open access
Semantic Scholar
Evolution of Conformation, Nanomechanics, and Infrared Nanospectroscopy of Single Amyloid Fibrils Converting into Microcrystals
J. Adamcik, F. Ruggeri, J. Berryman, Afang Zhang +2 more
2020Advancement of science34 citations Open access
Semantic Scholar
The Nt17 domain and its helical conformation regulate the aggregation, cellular properties and neurotoxicity of mutant huntingtin exon 1
S. Vieweg, Anne-Laure Mahul-Mellier, F. Ruggeri, Nathan Riguet +5 more
2021bioRxiv31 citations Open access
Semantic Scholar
Fabrication and Characterization of Reconstituted Silk Microgels for the Storage and Release of Small Molecules.
Xizhou Liu, Z. Toprakcioglu, A. Dear, A. Levin +8 more
2019Macromolecular rapid communications31 citations Open access
Semantic Scholar
Infrared nanospectroscopic mapping of a single metaphase chromosome
E. Lipiec, F. Ruggeri, C. Benadiba, A. Borkowska +7 more
2019Nucleic Acids Research28 citations Open access
Semantic Scholar

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