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T. Löhr · SciRah

Researcher profile · Semantic Scholar

T. Löhr

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T. Löhr — researcher profile on SciRah

h-index: 15
Works: 40
Citations: 2,180

Most-cited papers

Promoting transparency and reproducibility in enhanced molecular simulations
Massimiliano Bonomi, G. Bussi, C. Camilloni, G. A. Tribello +70 more
2019Nature Methods1,120 citations Open access
Semantic Scholar
Effects of α-tubulin acetylation on microtubule structure and stability
L. Eshun-Wilson, Rui Zhang, D. Portran, M. Nachury +6 more
2019Proceedings of the National Academy of Sciences of the United States of America290 citations Open access
Semantic Scholar
Small-molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer’s disease
Gabriella T. Heller, F. Aprile, T. Michaels, Ryan Limbocker +12 more
2019Science Advances147 citations Open access
Semantic Scholar
Discovery of highly potent and selective small molecule ADAMTS-5 inhibitors that inhibit human cartilage degradation via encoded library technology (ELT).
H. Deng, H. O'keefe, C. Davie, Kenneth E. Lind +21 more
2012Journal of Medicinal Chemistry128 citations Open access
Semantic Scholar
Translational Development of an ADAMTS-5 Antibody for Osteoarthritis Disease Modification
Jonathan Larkin, T. Löhr, L. Elefante, Jean Shearin +10 more
2015Osteoarthritis and Cartilage115 citations Open access
Semantic Scholar
A kinetic ensemble of the Alzheimer’s Aβ peptide
T. Löhr, Kai J. Kohlhoff, Gabriella T. Heller, C. Camilloni +1 more
2020Nature Computational Science56 citations Open access
Semantic Scholar
A Small Molecule Stabilizes the Disordered Native State of the Alzheimer’s Aβ Peptide
T. Löhr, Kai J. Kohlhoff, Gabriella T. Heller, C. Camilloni +1 more
2022ACS Chemical Neuroscience50 citations Open access
Semantic Scholar
Sample efficient reinforcement learning with active learning for molecular design
Michael Dodds, Jeff Guo, T. Löhr, Alessandro Tibo +2 more
2024Chemical Science41 citations Open access
Semantic Scholar
Metadynamic metainference: Convergence towards force field independent structural ensembles of a disordered peptide.
T. Löhr, Alexander Jussupow, C. Camilloni
2017Journal of Chemical Physics40 citations Open access
Semantic Scholar
An intrinsically disordered motif regulates the interaction between the p47 adaptor and the p97 AAA+ ATPase
Alexander E. Conicella, Rui Huang, Z. A. Ripstein, Ai Nguyen +6 more
2020Proceedings of the National Academy of Sciences of the United States of America27 citations Open access
Semantic Scholar
Pharmacokinetic Properties of Peptidic Radiopharmaceuticals: Reduced Uptake of (EH)3-Conjugates in Important Organs
M. Eder, T. Löhr, U. Bauder-Wüst, Markus Reber +4 more
2013Journal of Nuclear Medicine27 citations Open access
Semantic Scholar
Determination of the Structure and Dynamics of the Fuzzy Coat of an Amyloid Fibril of IAPP Using Cryo-Electron Microscopy
Z. F. Brotzakis, T. Löhr, Steven D. Truong, Samuel E. Hoff +2 more
2022bioRxiv25 citations Open access
Semantic Scholar
Determination of intermediate state structures in the opening pathway of SARS-CoV-2 spike using cryo-electron microscopy
Z. F. Brotzakis, T. Löhr, M. Vendruscolo
2020Chemical Science24 citations Open access
Semantic Scholar
Reviews Preclinical Safety and Immune-Modulating Effects of Therapeutic Monoclonal Antibodies to Interleukin-6 and Tumor Necrosis Factor-α in Cynomolgus Macaques
Pauline L. Martin, J. Cornacoff, U. Prabhakar, T. Löhr +4 more
2005Journal of Immunotoxicology21 citations Open access
Semantic Scholar
The highs and lows of translational drug development: antibody-mediated inhibition of ADAMTS-5 for osteoarthritis disease modification
J. Larkin, T. Löhr, L. Elefante, Jean Shearin +18 more
201415 citations Open access
Semantic Scholar
Neue Reaktionen von Schwefeldiimiden mit elektronenreichen und elektronenarmen Alkinen
H. Gotthardt, T. Löhr, D. J. Brauer
198712 citations
Semantic Scholar
Conformational Entropy as a Potential Liability of Computationally Designed Antibodies
T. Löhr, Pietro Sormanni, M. Vendruscolo
2022Biomolecules10 citations Open access
Semantic Scholar
Large-scale collaborative assessment of binding free energy calculations for drug discovery using OpenFE
Hannah M. Baumann, Joshua T. Horton, Michael M. Henry, Alyssa Travitz +38 more
2026Journal of Chemical Information and Modeling9 citations Open access
Semantic Scholar
A Practical Guide to the Simultaneous Determination of Protein Structure and Dynamics Using Metainference.
T. Löhr, C. Camilloni, Massimiliano Bonomi, M. Vendruscolo
2019Methods in molecular biology7 citations Open access
Semantic Scholar
Serial amplification of tau filaments using Alzheimer's brain homogenates and C322A or C322S recombinant tau
A. Santambrogio, S. Lövestam, Michael A. Metrick, T. Löhr +6 more
2025bioRxiv5 citations Open access
Semantic Scholar
Serum Amyloid A (SAA), C-reactive protein (CRP) and IL-6 as prognostic indicators in Renal Cell Carcinoma and Prostate Cancer.
M. Mata, T. Löhr, M. Lakshminarayanan, Kenneth Y. Lo +1 more
2004Journal of Clinical Oncology4 citations
Semantic Scholar
2‐(Aminothio)acrylamidine aus Schwefeldiimiden und Inaminen mit 3‐ständigem Wasserstoff
H. Gotthardt, T. Löhr
19874 citations
Semantic Scholar
Reaktionen von N-Sulfinylaminen und Sulfinen mit Inaminen
H. Gotthardt, T. Löhr
19874 citations
Semantic Scholar
Why are there no clinically-approved drugs targeting disordered proteins?
T. Löhr, Gogulan Karunanithy, Gabriella T. Heller
2026Current Opinion in Structural Biology3 citations Open access
Semantic Scholar
A small molecule stabilises the disordered native state of the Alzheimer’s Aβ peptide
T. Löhr, Kai J. Kohlhoff, Gabriella T. Heller, C. Camilloni +1 more
2021bioRxiv2 citations Open access
Semantic Scholar
Estimation of Ligand Binding Free Energy Using Multi-eGO
Bruno Stegani, E. Scalone, Fran Bačić Toplek, T. Löhr +4 more
2024Journal of Chemical Information and Modeling1 citations Open access
Semantic Scholar
Structure and Dynamics of Alzheimer's Associated Amyloid-Beta Peptide
T. Löhr, Kai J. Kohlhoff, Gabriella T. Heller, M. Vendruscolo
2019Biophysical Journal1 citations Open access
Semantic Scholar
SpinForecast: chain-free probabilistic backbone assignment of intrinsically disordered proteins from NMR chemical shifts
James T. Eaton, Jasmine Cornish, Kirsten M. Silvey, Pijush Chakraborty +3 more
2026bioRxiv0 citations Open access
Semantic Scholar
Serum immunoassays identify Cartilage Acidic Protein 1 (CRTAC1) as a biomarker of osteoarthritis
Yi He, J. Larkin, T. Löhr, M. Karsdal +1 more
2025Osteoarthritis and Cartilage0 citations Open access
Semantic Scholar
Navigating the Maize: Cyclic and conditional computational graphs for molecular simulation
T. Löhr, Michael Dodds, Lili Cao, Mikhail Kabeshov +4 more
2024Digital Discovery0 citations
Semantic Scholar
A brain‐seeded fibril amplification models the aggregation process of tau in Alzheimer’s disease for drug discovery
A. Santambrogio, Michael A. Metrick, T. Löhr, Robert I. Horne +1 more
2023Alzheimer's & Dementia0 citations Open access
Semantic Scholar
Entrepreneurial activity of graduates and students - what data is missing from university reporting?
C. Reinboth, K. Vogel, T. Löhr
20210 citations
Semantic Scholar
Unternehmerische Tätigkeit von Absolventinnen und Absolventen der Hochschule Harz - eine qualitative Analyse öffentlicher Datenquellen
T. Löhr, Christian Reinboth, Kathleen Vogel
20200 citations
Semantic Scholar
Crystal Structure of murine 12F4 Fab monoclonal antibody against ADAMTS5
J. Larkin, T. Löhr, L. Elefante, Jean Shearin +10 more
20150 citations
Semantic Scholar
Plate carrier assembly for a multi-plate clutch
H. Fuhrmann, T. Löhr, Christoph Lüftner, Johannes Kocherscheidt
20130 citations
Semantic Scholar
A method of operating a motor vehicle having two electric drives, as well as motor vehicle
Dirk Isgen, Tilo Koch, Dipl.-Ing. Peter Kunsch, T. Löhr +3 more
20100 citations
Semantic Scholar
Development, Optimization and Validation of Cell‐Based Assays – 1
M. Mata, T. Löhr
20080 citations
Semantic Scholar
Validation of the Cylex Technology to Measure T and B Cell Activation Capacity in Clinical Trials
M. Mata, T. Löhr, Jaymala Patel
20080 citations
Semantic Scholar
184 Pharmacokinetics of CNTO 328 in a three month intravenous dose toxicity study in cynomolgus monkeys with concomitant IL-2 therapy
Q. Jiao, U. Prabhakar, M. Frigo, T. Löhr +3 more
20040 citations
Semantic Scholar
Process and apparatus for the pretreatment of waste water by the use of chemicals
Frank Lockan, E. Lohr, T. Löhr
20030 citations
Semantic Scholar

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