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Giulia Fani · SciRah

Researcher profile · Semantic Scholar

Giulia Fani

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Giulia Fani — researcher profile on SciRah

h-index: 9
Works: 18
Citations: 360

Most-cited papers

Aβ Oligomers Dysregulate Calcium Homeostasis by Mechanosensitive Activation of AMPA and NMDA Receptors
Giulia Fani, B. Mannini, Giulia Vecchi, R. Cascella +4 more
2021ACS Chemical Neuroscience86 citations Open access
Semantic Scholar
Quantification of the Relative Contributions of Loss-of-function and Gain-of-function Mechanisms in TAR DNA-binding Protein 43 (TDP-43) Proteinopathies *
R. Cascella, C. Capitini, Giulia Fani, C. Dobson +2 more
2016Journal of Biological Chemistry82 citations Open access
Semantic Scholar
Quantitative assessment of the degradation of aggregated TDP‐43 mediated by the ubiquitin proteasome system and macroautophagy
R. Cascella, Giulia Fani, C. Capitini, P. Rusmini +3 more
2017The FASEB Journal36 citations Open access
Semantic Scholar
Misfolded protein oligomers induce an increase of intracellular Ca2+ causing an escalation of reactive oxidative species
Giulia Fani, Chiara Ester La Torre, R. Cascella, C. Cecchi +2 more
2022Cellular and Molecular Life Sciences27 citations Open access
Semantic Scholar
Isolation and characterization of soluble human full‐length TDP‐43 associated with neurodegeneration
M. V. Vega, Alessia Nigro, S. Luti, C. Capitini +4 more
2019The FASEB Journal27 citations
Semantic Scholar
Partial Failure of Proteostasis Systems Counteracting TDP-43 Aggregates in Neurodegenerative Diseases
R. Cascella, Giulia Fani, A. Bigi, F. Chiti +1 more
2019International Journal of Molecular Sciences23 citations Open access
Semantic Scholar
Full-length TDP-43 and its C-terminal domain form filaments in vitro having non-amyloid properties
C. Capitini, Giulia Fani, M. V. Vega, A. Penco +6 more
2020Amyloid: Journal of Protein Folding Disorders14 citations Open access
Semantic Scholar
Structural commonalities determined by physicochemical principles in the complex polymorphism of the amyloid state of proteins
Silvia Errico, Giulia Fani, Salvador Ventura, J. Schymkowitz +5 more
2024Biochemical Journal13 citations Open access
Semantic Scholar
Sphingosine 1‐phosphate attenuates neuronal dysfunction induced by amyloid‐β oligomers through endocytic internalization of NMDA receptors
A. Bigi, R. Cascella, Giulia Fani, C. Bernacchioni +5 more
2022The FEBS Journal10 citations Open access
Semantic Scholar
Differential interactome and innate immune response activation of two structurally distinct misfolded protein oligomers.
B. Mannini, Giulia Vecchi, A. Labrador-Garrido, Bertrand Fabre +8 more
2019ACS Chemical Neuroscience9 citations Open access
Semantic Scholar
Putative novel CSF biomarkers of Alzheimer’s disease based on the novel concept of generic protein misfolding and proteotoxicity: the PRAMA cohort
A. Bigi, Giulia Fani, V. Bessi, Liliana Napolitano +9 more
2024Translational Neurodegeneration8 citations Open access
Semantic Scholar
Soluble Prion Peptide 107–120 Protects Neuroblastoma SH-SY5Y Cells against Oligomers Associated with Alzheimer’s Disease
E. Rezvani-Boroujeni, S. Hosseini, Giulia Fani, C. Cecchi +1 more
2020International Journal of Molecular Sciences7 citations Open access
Semantic Scholar
Telomeric DNA damage response mediates neurotoxicity of Aβ42 oligomers in Alzheimer’s disease
Sara Sepe, Federica Rey, Alexandra Mancheno-Ferris, A. Bigi +13 more
2025EMBO Journal6 citations Open access
Semantic Scholar
Studying the trafficking of labeled trodusquemine and its application as nerve marker for light‐sheet and expansion microscopy
C. Capitini, L. Pesce, Giulia Fani, G. Mazzamuto +8 more
2022The FASEB Journal6 citations Open access
Semantic Scholar
Berberine mitigates neurotoxicity of misfolded protein oligomers by interacting with the cell membrane and subsequent internalization, without altering their structure.
Silvia Errico, Giulia Fani, Martina Gennari, Alessandra Mastricci +7 more
2025International Journal of Biological Macromolecules3 citations Open access
Semantic Scholar
Mechanosensitivity of N-methyl-D-aspartate receptors (NMDAR) is the key through which amyloid beta oligomers activate them
Giulia Fani, F. Chiti
2021Neural Regeneration Research3 citations Open access
Semantic Scholar
Natural aminosterols inhibit NMDA receptors with low nanomolar potency
Giulia Fani, E. Coppi, Silvia Errico, F. Cherchi +6 more
2025The FEBS Journal1 citations Open access
Semantic Scholar
Structure − Activity Relationship Study of Protoberberine Alkaloids Reveals Molecular Planarity as a Key Determinant of Membrane Interaction and Protection from Misfolded Protein Oligomers
Silvia Errico, A. Bigi, Giulia Fani, Monica Ambrosino +5 more
0 citations
Semantic Scholar

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F. Chiti×12
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F. Chiti — researcher profile on SciRah
C. Cecchi×8
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C. Cecchi — researcher profile on SciRah
R. Cascella×7
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R. Cascella — researcher profile on SciRah
C. Capitini×5
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C. Capitini — researcher profile on SciRah

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A. Bigi — researcher profile on SciRah

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B. Mannini — researcher profile on SciRah

Silvia Errico×4

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Silvia Errico — researcher profile on SciRah

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Michele Vendruscolo×3

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Fabrizio Chiti — researcher profile on SciRah