Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

Giuliana Fusco · SciRah

Researcher profile · Semantic Scholar

Giuliana Fusco

Share profile

Giuliana Fusco — researcher profile on SciRah

h-index: 21
Works: 53
Citations: 2,746

Most-cited papers

Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers
Giuliana Fusco, Serene W. Chen, P. Williamson, R. Cascella +9 more
2017Science637 citations Open access
Semantic Scholar
Direct Observation of the Three Regions in α-Synuclein that Determine its Membrane-Bound Behaviour
Giuliana Fusco, A. De Simone, Gopinath Tata, V. Vostrikov +3 more
2014Nature Communications456 citations Open access
Semantic Scholar
C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction
J. Lautenschläger, A. Stephens, Giuliana Fusco, Florian Ströhl +16 more
2018Nature Communications304 citations Open access
Semantic Scholar
Extent of N-terminus exposure of monomeric alpha-synuclein determines its aggregation propensity
A. Stephens, Maria Zacharopoulou, Rani Moons, Giuliana Fusco +9 more
2020Nature Communications148 citations Open access
Semantic Scholar
Structural basis of synaptic vesicle assembly promoted by α-synuclein
Giuliana Fusco, Tillmann Pape, A. Stephens, Pierre Mahou +7 more
2016Nature Communications124 citations Open access
Semantic Scholar
The docking of synaptic vesicles on the presynaptic membrane induced by α-synuclein is modulated by lipid composition
Wing K. Man, Bogachan Tahirbegi, Michail D. Vrettas, Swapan Preet +4 more
2021Nature Communications103 citations Open access
Semantic Scholar
Corrigendum: Structural basis of synaptic vesicle assembly promoted by α-synuclein
Giuliana Fusco, Tillmann Pape, A. Stephens, Pierre Mahou +7 more
2017Nature Communications101 citations Open access
Semantic Scholar
Structural Ensembles of Membrane-bound α-Synuclein Reveal the Molecular Determinants of Synaptic Vesicle Affinity
Giuliana Fusco, A. De Simone, P. Arosio, M. Vendruscolo +2 more
2016Scientific Reports96 citations Open access
Semantic Scholar
The N-terminal Acetylation of α-Synuclein Changes the Affinity for Lipid Membranes but not the Structural Properties of the Bound State
M. Runfola, A. De Simone, M. Vendruscolo, C. Dobson +1 more
2020Scientific Reports69 citations Open access
Semantic Scholar
Order and disorder in the physiological membrane binding of α-synuclein.
Giuliana Fusco, Máximo Sanz-Hernández, A. De Simone
2018Current Opinion in Structural Biology60 citations
Semantic Scholar
Conformational recognition of an intrinsically disordered protein.
James M. Krieger, Giuliana Fusco, Marc Lewitzky, P. Simister +4 more
2014Biophysical Journal57 citations Open access
Semantic Scholar
Membrane Interactions and Toxicity by Misfolded Protein Oligomers
M. Gonzalez-Garcia, Giuliana Fusco, A. De Simone
2021Frontiers in Cell and Developmental Biology56 citations Open access
Semantic Scholar
Structure–Toxicity Relationship in Intermediate Fibrils from α-Synuclein Condensates
Serene W. Chen, J. Barritt, R. Cascella, A. Bigi +8 more
2024Journal of the American Chemical Society51 citations Open access
Semantic Scholar
The toxicity of misfolded protein oligomers is independent of their secondary structure.
Mirella Vivoli Vega, R. Cascella, Serene W. Chen, Giuliana Fusco +4 more
2019ACS Chemical Biology47 citations
Semantic Scholar
Inhibition of α-Synuclein Fibril Elongation by Hsp70 Is Governed by a Kinetic Binding Competition between α-Synuclein Species.
F. Aprile, P. Arosio, Giuliana Fusco, Serene W. Chen +7 more
2017Biochemistry47 citations Open access
Semantic Scholar
Probing the Origin of the Toxicity of Oligomeric Aggregates of α-Synuclein with Antibodies
R. Cascella, Michele Perni, Serene W. Chen, Giuliana Fusco +5 more
2019ACS Chemical Biology45 citations Open access
Semantic Scholar
A Role of Cholesterol in Modulating the Binding of α-Synuclein to Synaptic-Like Vesicles
Wing K. Man, A. De Simone, J. Barritt, M. Vendruscolo +2 more
2020Frontiers in Neuroscience37 citations Open access
Semantic Scholar
Molecular determinants of the interaction of EGCG with ordered and disordered proteins
Giuliana Fusco, Máximo Sanz-Hernández, F. Ruggeri, M. Vendruscolo +2 more
2018Biopolymers35 citations Open access
Semantic Scholar
Structural Basis for Natural Product Selection and Export by Bacterial ABC Transporters.
M. Romano, Giuliana Fusco, H. Choudhury, S. Mehmood +8 more
2018ACS Chemical Biology34 citations Open access
Semantic Scholar
Modeling Parkinson’s Disease Neuropathology and Symptoms by Intranigral Inoculation of Preformed Human α-Synuclein Oligomers
L. Boi, A. Pisanu, Maria Francesca Palmas, Giuliana Fusco +12 more
2020International Journal of Molecular Sciences31 citations Open access
Semantic Scholar
Comparative Studies in the A30P and A53T α-Synuclein C. elegans Strains to Investigate the Molecular Origins of Parkinson's Disease
Michele Perni, A. T. van der Goot, Ryan Limbocker, T. V. van Ham +25 more
2021Frontiers in Cell and Developmental Biology24 citations Open access
Semantic Scholar
1H, 13C and 15N resonance assignments of human muscle acylphosphatase
Giuliana Fusco, A. De Simone, S. Hsu, Francesco Bemporad +3 more
2011Biomolecular NMR Assignments17 citations
Semantic Scholar
Repurposing Pomalidomide as a Neuroprotective Drug: Efficacy in an Alpha-Synuclein-Based Model of Parkinson’s Disease
Maria Francesca Palmas, A. Ena, Chiara Burgaletto, M. Casu +15 more
2022Neurotherapeutics14 citations Open access
Semantic Scholar
Immune responses to oligomeric α-synuclein in Parkinson’s disease peripheral blood mononuclear cells
A. F. Vega-Benedetti, Clara Porcedda, Tommaso Ercoli, Giuliana Fusco +12 more
2024Journal of Neurology13 citations Open access
Semantic Scholar
The Intranigral Infusion of Human-Alpha Synuclein Oligomers Induces a Cognitive Impairment in Rats Associated with Changes in Neuronal Firing and Neuroinflammation in the Anterior Cingulate Cortex
Maria Francesca Palmas, Michela Etzi, A. Pisanu, C. Camoglio +15 more
2022Cells13 citations Open access
Semantic Scholar
The role of structural dynamics in the thermal adaptation of hyperthermophilic enzymes
Giuliana Fusco, Francesco Bemporad, F. Chiti, C. Dobson +1 more
2022Frontiers in Molecular Biosciences12 citations Open access
Semantic Scholar
Metal interactions of α-synuclein probed by NMR amide-proton exchange
M. Gonzalez-Garcia, Giuliana Fusco, A. De Simone
2023Frontiers in Chemistry11 citations Open access
Semantic Scholar
Cryptic binding properties of a transient folding intermediate in a PDZ tandem repeat
F. Malagrinò, Giuliana Fusco, V. Pennacchietti, A. Toto +4 more
2022Protein Science11 citations Open access
Semantic Scholar
Local Ionic Conditions Modulate the Aggregation Propensity and Influence the Structural Polymorphism of α-Synuclein
M. Zacharopoulou, Neeleema Seetaloo, James F Ross, A. Stephens +10 more
2025Journal of the American Chemical Society10 citations Open access
Semantic Scholar
α-Synuclein and biological membranes: the danger of loving too much
Silvia Mansueto, Giuliana Fusco, A. De Simone
2023Chemical Communications10 citations Open access
Semantic Scholar
Local ionic conditions modulate the aggregation propensity and influence the structural polymorphism of alpha-synuclein
Maria Zacharopoulou, Neeleema Seetaloo, James F Ross, A. Stephens +10 more
2024bioRxiv9 citations Open access
Semantic Scholar
Protein kinase R dependent phosphorylation of α-synuclein regulates its membrane binding and aggregation
L. Reimer, Hjalte Gram, N. M. Jensen, C. Betzer +10 more
2022PNAS Nexus9 citations Open access
Semantic Scholar
α-Synuclein and Mitochondria: Probing the Dynamics of Disordered Membrane-protein Regions Using Solid-State Nuclear Magnetic Resonance
Angelo Gallo, Silvia Mansueto, Alessandro Emendato, Giuliana Fusco +1 more
2024JACS Au8 citations Open access
Semantic Scholar
Region-specific changes in gene expression are associated with cognitive deficits in the alpha-synuclein-induced model of Parkinson's disease: A transcriptomic profiling study.
M. F. Manchinu, Mauro Pala, Maria Francesca Palmas, Maria Antonietta Diana +10 more
2023Experimental Neurology8 citations Open access
Semantic Scholar
Copper2+ Binding to α-Synuclein. Histidine50 Can Form a Ternary Complex with Cu2+ at the N-Terminus but Not a Macrochelate.
Yao Tian, H. Stanyon, J. Barritt, Uroosa Mayet +4 more
2019Inorganic Chemistry8 citations Open access
Semantic Scholar
Catalytic Nanomaterials by Conjugation of an Artificial Heme-Peroxidase to Amyloid Fibrils.
Alessandra Esposito, Linda Leone, A. De Simone, Giuliana Fusco +2 more
2024ACS Applied Materials and Interfaces6 citations
Semantic Scholar
Post-fibrillization nitration of alpha-synuclein abolishes its seeding activity and pathology formation in primary neurons and in vivo
S. Donzelli, Sinead OSullivan, Anne-Laure Mahul-Mellier, A. Ulusoy +9 more
2023bioRxiv6 citations Open access
Semantic Scholar
Metabolomics Fingerprint Induced by the Intranigral Inoculation of Exogenous Human Alpha-Synuclein Oligomers in a Rat Model of Parkinson’s Disease
F. Murgia, L. Atzori, E. Carboni, M. L. Santoru +6 more
2020International Journal of Molecular Sciences5 citations Open access
Semantic Scholar
Thermal tuning of protein hydration in a hyperthermophilic enzyme
Giuliana Fusco, Carmen Biancaniello, Michail D. Vrettas, A. De Simone
2022Frontiers in Molecular Biosciences4 citations Open access
Semantic Scholar
Function, Regulation, and Dysfunction of Intrinsically Disordered Proteins
Giuliana Fusco, S. Gianni
2021Life3 citations Open access
Semantic Scholar
Extent of N-terminus exposure by altered long-range interactions of monomeric alpha-synuclein determines its aggregation propensity
A. Stephens, Maria Zacharopoulou, Rani Moons, Giuliana Fusco +9 more
2019bioRxiv3 citations Open access
Semantic Scholar
Aggregation and membrane activity of mutant A30P alpha-synuclein on mitochondrial membranes.
Maja Herrera, Adam El Saghir, Silvia Mansueto, Stephanie Ghio +3 more
2026International Journal of Biological Macromolecules2 citations Open access
Semantic Scholar
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
Silvia Arino, Giuliana Fusco, A. De Simone
2026FEBS Letters1 citations Open access
Semantic Scholar
Cellular prion protein and calcium ions trigger the neurotoxicity of α-synuclein aggregates
A. Bigi, A. Conti, Liliana Napolitano, Giuliana Fusco +4 more
2025Cell & Bioscience1 citations Open access
Semantic Scholar
A unified in vitro to in vivo fluorescence lifetime screening platform yields amyloid β aggregation inhibitors
S. Collins, Liisa D. van Vliet, Fabrice Gielen, M. Janecek +9 more
2022bioRxiv1 citations Open access
Semantic Scholar
α-Synuclein Facilitates Spontaneous Dopamine Release in a Calcium- and Phosphorylation-Dependent Manner
Yu-Qing Feng, A. Stephens, P. V. Ramirez, E. Mosharov +13 more
2026bioRxiv0 citations Open access
Semantic Scholar
Low-abundance αSyn-112 promotes αSyn-140 aggregation in vitro and forms immunoreactive deposits in Parkinson’s disease brain tissue
Alexander Röntgen, Giuliana Fusco, Jonathan C. Breiter, Joseph S. Beckwith +9 more
2026bioRxiv0 citations Open access
Semantic Scholar
Brain cholesterol metabolites cause significant neurodegeneration in human iPSC-derived neurons
Yu-Qing Feng, Bismoy Mazumder, Tasuku Konno, Ernestine Hui +15 more
2025bioRxiv0 citations Open access
Semantic Scholar
Abstract P383: Increased renal afferent nerve activity and peak response to pro-inflammatory cytokine interleukin 6 in isolated dorsal root ganglion neurons from hypertensive rats
Sebastien Hayoz, Mason G. Adams, Deanna Clinch, Thaiane Foster +12 more
2024HYPERTENSION0 citations
Semantic Scholar
Calcium binding at the C-terminus of α-synuclein modulates synaptic vesicle 2 interaction 3 4 5
J. Lautenschläger, A. Stephens, Giuliana Fusco, Florian Ströhl +18 more
20180 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

A. De Simone×45
Invite
A. De Simone — researcher profile on SciRah
C. Dobson×14
Invite
C. Dobson — researcher profile on SciRah
M. Vendruscolo×13
Invite
M. Vendruscolo — researcher profile on SciRah
A. Stephens×10
Invite
A. Stephens — researcher profile on SciRah

×6

Invite

Serene W. Chen — researcher profile on SciRah

Invite

J. Phillips — researcher profile on SciRah

Invite

C. Kaminski — researcher profile on SciRah

Invite

R. Cascella — researcher profile on SciRah

Invite

C. Cecchi — researcher profile on SciRah

Invite

F. Chiti — researcher profile on SciRah

Maria Zacharopoulou×5

Invite

Maria Zacharopoulou — researcher profile on SciRah

Invite

A. Pisanu — researcher profile on SciRah