Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

Pei-Shen Zhao · SciRah

Researcher profile · Semantic Scholar

Pei-Shen Zhao

Share profile

Pei-Shen Zhao — researcher profile on SciRah

h-index: 26
Works: 60
Citations: 2,904

Most-cited papers

Phase-plate cryo-EM structure of a biased agonist-bound human GLP-1 receptor–Gs complex
Yi-Lynn Liang, M. Khoshouei, A. Glukhova, S. Furness +14 more
2018Nature301 citations Open access
Semantic Scholar
Biased Signaling of Protease-Activated Receptors
Pei-Shen Zhao, Matthew C. Metcalf, N. Bunnett
2014Frontiers in Endocrinology246 citations Open access
Semantic Scholar
The Bile Acid Receptor TGR5 Activates the TRPA1 Channel to Induce Itch in Mice
T. Lieu, G. Jayaweera, Pei-Shen Zhao, D. Poole +14 more
2014Gastroenterology210 citations Open access
Semantic Scholar
Differential GLP-1R binding and activation by peptide and non-peptide agonists
Xin Zhang, M. Belousoff, Pei-Shen Zhao, A. Kooistra +18 more
2020bioRxiv188 citations Open access
Semantic Scholar
Cathepsin S Causes Inflammatory Pain via Biased Agonism of PAR2 and TRPV4*
Pei-Shen Zhao, T. Lieu, N. Barlow, Matthew C. Metcalf +15 more
2014Journal of Biological Chemistry176 citations Open access
Semantic Scholar
Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome
N. Jiménez-Vargas, Luke A. Pattison, Pei-Shen Zhao, T. Lieu +23 more
2018Proceedings of the National Academy of Sciences of the United States of America156 citations Open access
Semantic Scholar
Neutrophil Elastase Activates Protease-activated Receptor-2 (PAR2) and Transient Receptor Potential Vanilloid 4 (TRPV4) to Cause Inflammation and Pain*
Pei-Shen Zhao, T. Lieu, N. Barlow, Silvia Sostegni +6 more
2015Journal of Biological Chemistry152 citations Open access
Semantic Scholar
Activation of the GLP-1 receptor by a non-peptidic agonist
Pei-Shen Zhao, Yi-Lynn Liang, M. Belousoff, Giuseppe Deganutti +16 more
2020Nature148 citations Open access
Semantic Scholar
Structural basis of Gs and Gi recognition by the human glucagon receptor
Anna Qiao, Shuo Han, Xinmei Li, Zhixin Li +16 more
2020Science141 citations
Semantic Scholar
Dominant Negative G Proteins Enhance Formation and Purification of Agonist-GPCR-G Protein Complexes for Structure Determination.
Yi-Lynn Liang, Pei-Shen Zhao, C. Draper-Joyce, Joanne Baltos +7 more
2018ACS Pharmacology & Translational Science132 citations Open access
Semantic Scholar
Toward a Structural Understanding of Class B GPCR Peptide Binding and Activation.
Yi-Lynn Liang, M. Belousoff, Pei-Shen Zhao, C. Koole +11 more
2020Molecules and Cells103 citations Open access
Semantic Scholar
Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation
Giuseppe Deganutti, Yi-Lynn Liang, Xin Zhang, M. Khoshouei +14 more
2021bioRxiv77 citations Open access
Semantic Scholar
Translational control by RGS2
C. Nguyen, Ming Hong, Pei-Shen Zhao, Lynne Hugendubler +3 more
2009Journal of Cell Biology68 citations Open access
Semantic Scholar
AM833 Is a Novel Agonist of Calcitonin Family G Protein–Coupled Receptors: Pharmacological Comparison with Six Selective and Nonselective Agonists
Madeleine M. Fletcher, Peter Keov, Tin T. Truong, G. Mennen +7 more
2021Journal of Pharmacology and Experimental Therapeutics58 citations Open access
Semantic Scholar
Structural and Functional Diversity among Agonist-Bound States of the GLP-1 Receptor
B. P. Cary, Giuseppe Deganutti, Pei-Shen Zhao, Tin T. Truong +7 more
2021bioRxiv53 citations Open access
Semantic Scholar
Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonism
Sai-Fei Lei, Lachlan Clydesdale, A. Dai, Xiao-qing Cai +10 more
2018Journal of Biological Chemistry51 citations Open access
Semantic Scholar
Glucagon‐like peptide‐1 receptor internalisation controls spatiotemporal signalling mediated by biased agonists
Madeleine M. Fletcher, M. Halls, Pei-Shen Zhao, Lachlan Clydesdale +3 more
2018Biochemical Pharmacology50 citations
Semantic Scholar
Pharmacological characterization of mono-, dual- and tri- peptidic agonists at GIP and GLP-1 receptors.
Elita Yuliantie, Sanaz Darbalaei, A. Dai, Pei-Shen Zhao +4 more
2020Biochemical Pharmacology44 citations
Semantic Scholar
The involvement of the Wnt/β-catenin signaling cascade in fibrosis progression and its therapeutic targeting by relaxin.
Deidree V N Somanader, Pei-Shen Zhao, R. Widdop, C. Samuel
2024Biochemical Pharmacology42 citations Open access
Semantic Scholar
Granzyme A in Chikungunya and Other Arboviral Infections
Alessandra Soares-Schanoski, T. Le, D. Kaiserman, C. Rowe +11 more
2020Frontiers in Immunology36 citations Open access
Semantic Scholar
Agonist-biased Trafficking of Somatostatin Receptor 2A in Enteric Neurons*
Pei-Shen Zhao, M. Canals, Jane E. Murphy, D. Klingler +5 more
2013Journal of Biological Chemistry36 citations Open access
Semantic Scholar
The role of G protein-coupled receptor kinases in GLP-1R β-arrestin recruitment and internalisation.
Samantha M. McNeill, Jessica Lu, Carlo Marion C. Carino, A. Inoue +3 more
2024Biochemical Pharmacology33 citations Open access
Semantic Scholar
Targeting VIP and PACAP Receptor Signaling: New Insights into Designing Drugs for the PACAP Subfamily of Receptors
Jessica Lu, S. Piper, Pei-Shen Zhao, L. Miller +2 more
2022International Journal of Molecular Sciences33 citations Open access
Semantic Scholar
Granzyme K initiates IL-6 and IL-8 release from epithelial cells by activating protease-activated receptor 2
D. Kaiserman, Pei-Shen Zhao, C. Rowe, Andrea Leong +8 more
2022PLoS ONE31 citations Open access
Semantic Scholar
Evaluation of biased agonism mediated by dual agonists of the GLP-1 and glucagon receptors.
Sanaz Darbalaei, Elita Yuliantie, A. Dai, Rulue Chang +5 more
2020Biochemical Pharmacology29 citations
Semantic Scholar
Resistance to age-related, normal body weight gain in RGS2 deficient mice.
C. Nunn, Pei-Shen Zhao, Min-Xu Zou, K. Summers +2 more
2011Cellular Signalling29 citations
Semantic Scholar
The nature of efficacy at G protein-coupled receptors.
Pei-Shen Zhao, S. Furness
2019Biochemical Pharmacology24 citations
Semantic Scholar
Lipoxin A4 improves cardiac remodeling and function in diabetes-associated cardiac dysfunction
Ting Fu, Muthukumar Mohan, Madhura Bose, E. Brennan +11 more
2024Cardiovascular Diabetology22 citations Open access
Semantic Scholar
Protein Kinase D and Gβγ Subunits Mediate Agonist-evoked Translocation of Protease-activated Receptor-2 from the Golgi Apparatus to the Plasma Membrane*
D. Jensen, Pei-Shen Zhao, N. Jiménez-Vargas, T. Lieu +6 more
2016Journal of Biological Chemistry22 citations Open access
Semantic Scholar
The Ras-Binding Domain Region of Rgs14 Regulates Its Functional Interactions With Heterotrimeric G Proteins
Pei-Shen Zhao, C. Nunn, Suneela Ramineni, J. Hepler +1 more
2013Journal of Cellular Biochemistry21 citations Open access
Semantic Scholar
RGS2 is a component of the cellular stress response.
C. Nguyen, Pei-Shen Zhao, Alina J. Sobiesiak, P. Chidiac
2012Biochemical and Biophysical Research Communications - BBRC21 citations
Semantic Scholar
Understanding VPAC receptor family peptide binding and selectivity
S. Piper, Giuseppe Deganutti, Jessica Lu, Pei-Shen Zhao +9 more
2022Nature Communications20 citations Open access
Semantic Scholar
RAMPs regulate signalling bias and internalisation of the GIPR
Matthew Harris, Duncan I. Mackie, J. B. Pawlak, Sabrina Carvalho +17 more
2021bioRxiv19 citations Open access
Semantic Scholar
The Proline-rich N-terminal Domain of G18 Exhibits a Novel G Protein Regulatory Function*
Pei-Shen Zhao, C. Nguyen, P. Chidiac
2010Journal of Biological Chemistry16 citations Open access
Semantic Scholar
Fine-tuning of GPCR signals by intracellular G protein modulators.
Pei-Shen Zhao, W. Cladman, H. V. van Tol, P. Chidiac
2013Progress in Molecular Biology and Translational Science15 citations
Semantic Scholar
Biased receptor signalling and intracellular trafficking profiles of structurally distinct formylpeptide receptor 2 agonists
Cheng Peng, E. A. Vecchio, A. T. Nguyen, Mia De Seram +9 more
2024British Journal of Pharmacology14 citations Open access
Semantic Scholar
Implications of ligand-receptor binding kinetics on GLP-1R signalling.
Pei-Shen Zhao, Tin T. Truong, Jon Merlin, P. Sexton +1 more
2022Biochemical Pharmacology13 citations Open access
Semantic Scholar
Engineering of a Biologically Active Glycosylated Glucagon-Like Peptide-1 Analogue.
C. Chandrashekar, Feng Lin, Yuji Nishiuchi, Sam F Mohammed +12 more
2024Journal of Medicinal Chemistry12 citations
Semantic Scholar
Corrigendum: Biased Signaling of Protease-Activated Receptors
Pei-Shen Zhao, Matthew C. Metcalf, N. Bunnett
2015Frontiers in Endocrinology11 citations Open access
Semantic Scholar
Glycosylation Improves the Proteolytic Stability of Exenatide.
C. Chandrashekar, Y. Nishiuchi, Barbara F White, Yanni Arsenakis +10 more
2023Bioconjugate chemistry10 citations
Semantic Scholar
Protein kinase D and Gβγ mediate sustained nociceptive signaling by biased agonists of protease-activated receptor-2
Pei-Shen Zhao, Luke A. Pattison, D. Jensen, N. Jiménez-Vargas +8 more
2019Journal of Biological Chemistry10 citations Open access
Semantic Scholar
Demonstration of elevated levels of active cathepsin S in dextran sulfate sodium colitis using a new activatable probe
N. Barlow, Yasmin Nasser, Pei-Shen Zhao, Namit Sharma +11 more
2015Neurogastroenterology and Motility7 citations
Semantic Scholar
Regulation of RGS5 GAP activity by GPSM3
Pei-Shen Zhao, P. Chidiac
2015Molecular and Cellular Biochemistry7 citations
Semantic Scholar
Chemical Synthesis and Characterization of a Nonfibrillating Glycoglucagon.
Mengjie Liu, Pei-Shen Zhao, M. Uddin, Wen-Yi Li +8 more
2021Bioconjugate chemistry5 citations
Semantic Scholar
The roles of RGS proteins in cardiometabolic disease
Samantha M. McNeill, Pei-Shen Zhao
2023British Journal of Pharmacology4 citations Open access
Semantic Scholar
Structural basis of modified ligand selectivity from N-terminal PAC1R alternative splicing
Jessica Lu, Giuseppe Deganutti, Miao-Miao Li, Laura J Humphrys +10 more
2025Proceedings of the National Academy of Sciences of the United States of America3 citations Open access
Semantic Scholar
Unique Biased Agonism Profile of βCGRP on CGRP Family Receptors.
G. Mennen, Z. Ying, Madeleine M. Fletcher, M. A. Razzak +5 more
2025Biochemistry3 citations
Semantic Scholar
Cholesterol-dependent dynamic changes in the conformation of the type 1 cholecystokinin receptor affect ligand binding and G protein coupling
K. Harikumar, Pei-Shen Zhao, B. P. Cary, Xiaomeng Xu +10 more
2024PLoS Biology3 citations Open access
Semantic Scholar
Global Sirt5 deletion reshapes gut microbiota and impairs glucose metabolism in high-fat diet-induced obese mice.
Hui Cao, Kejia Xu, Xiaojue Li, Quan Liu +11 more
2025Biochemical and Biophysical Research Communications - BBRC1 citations
Semantic Scholar
519 Neutrophil Elastase Activates a PAR2/TRPV4 Signaling Complex to Cause Inflammatory Pain
Pei-Shen Zhao, T. Lieu, S. Vanner, N. Bunnett
20151 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

D. Wootten×23
Invite
D. Wootten — researcher profile on SciRah
P. Sexton×18
Invite
P. Sexton — researcher profile on SciRah
N. Bunnett×12
Invite
N. Bunnett — researcher profile on SciRah
Tin T. Truong×10
Invite
Tin T. Truong — researcher profile on SciRah

A. Christopoulos

×10

Invite

A. Christopoulos — researcher profile on SciRah

Yi-Lynn Liang×8

Invite

Yi-Lynn Liang — researcher profile on SciRah

Invite

T. Lieu — researcher profile on SciRah

Invite

R. Danev — researcher profile on SciRah

Invite

P. Chidiac — researcher profile on SciRah

Ming-Wei Wang×6

Invite

Ming-Wei Wang — researcher profile on SciRah

Invite

D. Poole — researcher profile on SciRah

M. Belousoff×6

Invite

M. Belousoff — researcher profile on SciRah