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E. Brennan · SciRah

Researcher profile · Semantic Scholar

E. Brennan

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E. Brennan — researcher profile on SciRah

h-index: 34
Works: 104
Citations: 9,506

Most-cited papers

Genetic studies of body mass index yield new insights for obesity biology
A. Locke, B. Kahali, S. Berndt, A. Justice +478 more
2015Nature4,398 citations Open access
Semantic Scholar
New genetic loci link adipose and insulin biology to body fat distribution
D. Shungin, T. Winkler, Damien C. Croteau-Chonka, T. Ferreira +402 more
2015Nature1,551 citations Open access
Semantic Scholar
Mesenchymal Stem Cells Deliver Exogenous MicroRNA-let7c via Exosomes to Attenuate Renal Fibrosis.
Bo Wang, Ke-qun Yao, Brooke M. Huuskes, Hsin-Hui Shen +6 more
2016Molecular Therapy354 citations Open access
Semantic Scholar
New Susceptibility Loci Associated with Kidney Disease in Type 1 Diabetes
N. Sandholm, R. Salem, A. McKnight, E. Brennan +88 more
2012PLoS Genetics279 citations Open access
Semantic Scholar
Association Testing of Previously Reported Variants in a Large Case-Control Meta-analysis of Diabetic Nephropathy
W. Williams, R. Salem, A. McKnight, N. Sandholm +36 more
2011Diabetes263 citations Open access
Semantic Scholar
Pro-resolving lipid mediators: regulators of inflammation, metabolism and kidney function
E. Brennan, P. Kantharidis, M. Cooper, C. Godson
2021Nature Reviews Nephrology241 citations Open access
Semantic Scholar
Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen.
R. Salem, Jennifer N. Todd, N. Sandholm, Joanne B. Cole +84 more
2019Journal of the American Society of Nephrology178 citations Open access
Semantic Scholar
Protective Effect of let-7 miRNA Family in Regulating Inflammation in Diabetes-Associated Atherosclerosis
E. Brennan, Bo Wang, A. McClelland, Muthukumar Mohan +15 more
2017Diabetes156 citations Open access
Semantic Scholar
Lipoxins attenuate renal fibrosis by inducing let-7c and suppressing TGFβR1.
E. Brennan, K. Nolan, Emma Börgeson, Oisín S. Gough +11 more
2013Journal of the American Society of Nephrology148 citations Open access
Semantic Scholar
The Atlas of Inflammation Resolution (AIR)
C. Serhan, S. Gupta, M. Perretti, C. Godson +26 more
2020Molecular Aspects of Medicine118 citations Open access
Semantic Scholar
The Genetics of Diabetic Nephropathy
E. Brennan, C. Mcevoy, D. Sadlier, C. Godson +1 more
2013Genes87 citations Open access
Semantic Scholar
Next-Generation Sequencing Identifies TGF-β1-Associated Gene Expression Profiles in Renal Epithelial Cells Reiterated in Human Diabetic Nephropathy
E. Brennan, Melissa J. Morine, David W. Walsh, S. Roxburgh +8 more
2012Biochimica et Biophysica Acta84 citations Open access
Semantic Scholar
Lipoxins Protect Against Inflammation in Diabetes-Associated Atherosclerosis
E. Brennan, Muthukumar Mohan, A. McClelland, M. de Gaetano +20 more
2018Diabetes81 citations Open access
Semantic Scholar
Formylpeptide receptor 2: Nomenclature, structure, signalling and translational perspectives: IUPHAR review 35
Cheng-Xue Qin, L. Norling, E. A. Vecchio, E. Brennan +5 more
2022British Journal of Pharmacology75 citations Open access
Semantic Scholar
Genetic Evidence for a Causal Role of Obesity in Diabetic Kidney Disease
Jennifer N. Todd, E. Dahlström, R. Salem, N. Sandholm +9 more
2015Diabetes70 citations Open access
Semantic Scholar
Therapeutic Potential of Lipoxin A4 in Chronic Inflammation: Focus on Cardiometabolic Disease.
T. Fu, Muthukumar Mohan, E. Brennan, O. Woodman +4 more
2020ACS Pharmacology & Translational Science68 citations Open access
Semantic Scholar
Chromosome 2q31.1 associates with ESRD in women with type 1 diabetes.
N. Sandholm, A. McKnight, R. Salem, E. Brennan +19 more
2013Journal of the American Society of Nephrology65 citations Open access
Semantic Scholar
Lipoxins Regulate the Early Growth Response-1 Network and Reverse Diabetic Kidney Disease.
E. Brennan, Muthukumar Mohan, A. McClelland, C. Tikellis +12 more
2018Journal of the American Society of Nephrology64 citations Open access
Semantic Scholar
Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque reactivity
S. Oggero, M. de Gaetano, S. Marcone, Stephen Fitzsimons +12 more
2021Journal of Extracellular Vesicles58 citations Open access
Semantic Scholar
Recent advances in the design and development of formyl peptide receptor 2 (FPR2/ALX) agonists as pro-resolving agents with diverse therapeutic potential.
M. Maciuszek, Antonino Cacace, E. Brennan, C. Godson +1 more
2021European journal of medicinal chemistry58 citations Open access
Semantic Scholar
Genome-wide meta-analysis and omics integration identifies novel genes associated with diabetic kidney disease
N. Sandholm, Joanne B. Cole, V. Nair, Xin Sheng +27 more
2021Diabetologia57 citations Open access
Semantic Scholar
Therapeutic Potential of Pro-Resolving Mediators in Diabetic Kidney Disease.
T. Vartak, C. Godson, E. Brennan
2021Advanced Drug Delivery Reviews53 citations Open access
Semantic Scholar
Assessment of differentially methylated loci in individuals with end-stage kidney disease attributed to diabetic kidney disease: an exploratory study
L. Smyth, J. Kilner, V. Nair, H. Liu +24 more
2021Clinical Epigenetics53 citations Open access
Semantic Scholar
Epigenome-wide meta-analysis identifies DNA methylation biomarkers associated with diabetic kidney disease
L. Smyth, E. Dahlström, A. Syreeni, K. Kerr +24 more
2022Nature Communications49 citations Open access
Semantic Scholar
Liraglutide Attenuates Preestablished Atherosclerosis in Apolipoprotein E–Deficient Mice via Regulation of Immune Cell Phenotypes and Proinflammatory Mediators
R. Bruen, S. Curley, S. Kajani, G. Lynch +7 more
2019Journal of Pharmacology and Experimental Therapeutics48 citations Open access
Semantic Scholar
Lipoxin Mimetics and the Resolution of Inflammation.
C. Godson, P. Guiry, E. Brennan
2023Annual Review of Pharmacology and Toxicology47 citations Open access
Semantic Scholar
microRNA-155 Is Decreased During Atherosclerosis Regression and Is Increased in Urinary Extracellular Vesicles During Atherosclerosis Progression
Stephen Fitzsimons, S. Oggero, R. Bruen, Cathal M. McCarthy +7 more
2020Frontiers in Immunology46 citations Open access
Semantic Scholar
NR4A Receptors Differentially Regulate NF-κB Signaling in Myeloid Cells
C. Mcevoy, M. de Gaetano, Hugh E. Giffney, B. Bahar +7 more
2017Frontiers in Immunology45 citations Open access
Semantic Scholar
Asymmetric synthesis and biological evaluation of imidazole- and oxazole-containing synthetic lipoxin A4 mimetics (sLXms).
M. de Gaetano, E. Butler, Kevin Gahan, Andrea Zanetti +13 more
2019European journal of medicinal chemistry44 citations Open access
Semantic Scholar
Specialized Pro-resolving Lipid Mediators: Modulation of Diabetes-Associated Cardio-, Reno-, and Retino-Vascular Complications
M. de Gaetano, C. Mcevoy, D. Andrews, Antonino Cacace +3 more
2018Frontiers in Pharmacology39 citations Open access
Semantic Scholar
The dual role of lipids in chronic kidney disease: Pathogenic culprits and therapeutic allies.
E. Giardini, D. Moore, D. Sadlier, C. Godson +1 more
2024Atherosclerosis38 citations Open access
Semantic Scholar
The Atlas of Inflammation-Resolution (AIR)
C. Serhan, S. Gupta, M. Perretti, C. Godson +25 more
2020bioRxiv38 citations Open access
Semantic Scholar
Therapeutic potential of the FPR2/ALX agonist AT-01-KG in the resolution of articular inflammation.
I. Galvão, Eliza M. Melo, V. D. de Oliveira, J. Vago +7 more
2021Pharmacological Research36 citations Open access
Semantic Scholar
Specialized pro-resolving mediators in renal fibrosis.
E. Brennan, Antonino Cacace, C. Godson
2017Molecular Aspects of Medicine35 citations
Semantic Scholar
Quantum Contextuality with Stabilizer States
Mark Howard, E. Brennan, J. Vala
2013Entropy27 citations Open access
Semantic Scholar
Dysregulation of the interleukin-17A pathway in endometrial tissue from women with unexplained infertility affects pregnancy outcome following assisted reproductive treatment.
David A. Crosby, L. Glover, E. Brennan, P. Kelly +10 more
2020Human Reproduction26 citations Open access
Semantic Scholar
Macrophage DNases Limit Neutrophil Extracellular Trap–Mediated Defective Efferocytosis in Atherosclerosis
U. Dhawan, T. Vartak, H. Englert, Stefan Russo +13 more
2025Circulation Research24 citations
Semantic Scholar
Asymmetric Synthesis and Biological Screening of Quinoxaline-Containing Synthetic Lipoxin A4 Mimetics (QNX-sLXms)
M. de Gaetano, Catherine Tighe, Kevin Gahan, Andrea Zanetti +13 more
2021Journal of Medicinal Chemistry23 citations Open access
Semantic Scholar
Lipoxin A4 improves cardiac remodeling and function in diabetes-associated cardiac dysfunction
Ting Fu, Muthukumar Mohan, Madhura Bose, E. Brennan +11 more
2024Cardiovascular Diabetology22 citations Open access
Semantic Scholar
RAGE Deletion Confers Renoprotection by Reducing Responsiveness to Transforming Growth Factor-β and Increasing Resistance to Apoptosis
Shinji Hagiwara, K. Sourris, M. Ziemann, Tieqiao Wu +14 more
2018Diabetes22 citations Open access
Semantic Scholar
Study of microRNA in diabetic nephropathy: Isolation, quantification and biological function
P. Kantharidis, Shinji Hagiwara, E. Brennan, A. McClelland
2015Nephrology22 citations
Semantic Scholar
Paricalcitol protects against TGF-β1-induced fibrotic responses in hypoxia and stabilises HIF-α in renal epithelia.
K. Nolan, E. Brennan, Carsten C. Scholz, C. Cullen +3 more
2015Experimental Cell Research22 citations
Semantic Scholar
Specialized pro-resolving mediators in diabetes: novel therapeutic strategies.
E. Brennan, Muthukumar Mohan, D. Andrews, Madhura Bose +1 more
2019Clinical science20 citations
Semantic Scholar
Decoding microRNA drivers in atherosclerosis
T. Vartak, Soundharya Kumaresan, E. Brennan
2022Bioscience Reports18 citations Open access
Semantic Scholar
High sensitivity DNA detection based on regioselectively decorated electrocatalytic nanoparticles.
Elaine Spain, E. Brennan, H. McArdle, T. Keyes +1 more
2012Analytical Chemistry17 citations
Semantic Scholar
Profibrotic IHG-1 complexes with renal disease associated HSPA5 and TRAP1 in mitochondria.
Úna Bhreathnach, B. Griffin, E. Brennan, Leah M Ewart +2 more
2017Biochimica et Biophysica Acta - Molecular Basis of Disease16 citations Open access
Semantic Scholar
Induction of let-7d-5p miRNA modulates aortic smooth muscle inflammatory signaling and phenotypic switching.
T. Vartak, E. Giardini, D P Kelly, B. Moran +4 more
2024Atherosclerosis14 citations Open access
Semantic Scholar
Dietary Restriction and Medical Therapy Drives PPARα-Regulated Improvements in Early Diabetic Kidney Disease in Male Rats
William P. Martin, M. Nair, Y. H. D. Chuah, Daniel Malmodin +12 more
2022Clinical science14 citations Open access
Semantic Scholar
Diagnostic utility of genetic testing in patients undergoing renal biopsy
K. Benson, S. Murray, Ross Doyle, B. Doyle +7 more
2020Cold Spring Harbor molecular case studies13 citations Open access
Semantic Scholar
TRIB3 Links Endoplasmic Reticulum Stress to Impaired Efferocytosis in Atherosclerosis
A. Singhal, Stefan Russo, U. Dhawan, Kunzangla Bhutia +14 more
2025Circulation Research12 citations Open access
Semantic Scholar

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