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G. Douglas · SciRah

Researcher profile · Semantic Scholar

G. Douglas

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G. Douglas — researcher profile on SciRah

h-index: 34
Works: 133
Citations: 5,322

Most-cited papers

IPCS guidelines for the monitoring of genotoxic effects of carcinogens in humans. International Programme on Chemical Safety.
R. Albertini, D. Anderson, G. Douglas, L. Hagmar +8 more
2000Mutation research793 citations
Semantic Scholar
Detailed review of transgenic rodent mutation assays.
I. Lambert, Tim Singer, Sherri E Boucher, G. Douglas
2005Mutation research365 citations
Semantic Scholar
Germ-line mutations, DNA damage, and global hypermethylation in mice exposed to particulate air pollution in an urban/industrial location
C. Yauk, Aris A. Polyzos, A. Rowan-Carroll, C. Somers +8 more
2008Proceedings of the National Academy of Sciences of the United States of America308 citations Open access
Semantic Scholar
Acrylamide: a review of its genotoxicity and an assessment of heritable genetic risk.
K. Dearfield, G. Douglas, U. Ehling, M. Moore +2 more
1995Mutation research303 citations
Semantic Scholar
Comprehensive comparison of six microarray technologies.
C. Yauk, M. Berndt, Andrew Williams, G. Douglas
2004Nucleic Acids Research247 citations Open access
Semantic Scholar
Mutagenicity testing for chemical risk assessment: update of the WHO/IPCS Harmonized Scheme.
D. Eastmond, A. Hartwig, D. Anderson, W. Anwar +6 more
2009Mutagenesis202 citations Open access
Semantic Scholar
In vivo transgenic mutation assays.
V. Thybaud, S. Dean, T. Nohmi, J. de Boer +10 more
2003Mutation research172 citations
Semantic Scholar
Mutagenic and carcinogenic hazards of settled house dust. I: Polycyclic aromatic hydrocarbon content and excess lifetime cancer risk from preschool exposure.
Rebecca M. Maertens, Xiao-Feng Yang, Ji-Ping Zhu, R. Gagné +2 more
2008Environmental Science and Technology157 citations Open access
Semantic Scholar
Mainstream tobacco smoke causes paternal germ-line DNA mutation.
C. Yauk, M. Berndt, Andrew Williams, A. Rowan-Carroll +2 more
2007Cancer Research105 citations Open access
Semantic Scholar
Sequence spectra of spontaneous lacZ gene mutations in transgenic mouse somatic and germline tissues.
G. Douglas, J. Gingerich, Jan A. Gossen, Sheryl A. Barlett
1994Mutagenesis90 citations
Semantic Scholar
In vivo transgenic mutation assays
J. Heddle, S. Dean, T. Nohmi, M. Boerrigter +10 more
2000Environmental and Molecular Mutagenesis89 citations
Semantic Scholar
Approaches for identifying germ cell mutagens: Report of the 2013 IWGT workshop on germ cell assays(☆).
C. Yauk, M. Aardema, J. van Benthem, J. Bishop +11 more
2015Mutation Research. Genetic Toxicology and Environmental Mutagenesis78 citations Open access
Semantic Scholar
Meeting Report: Validation of Toxicogenomics-Based Test Systems: ECVAM–ICCVAM/NICEATM Considerations for Regulatory Use
R. Corvi, H. Ahr, S. Albertini, D. Blakey +20 more
2005Environmental Health Perspectives76 citations Open access
Semantic Scholar
Molecular insight into the effects of hypothyroidism on the developing cerebellum.
Hongyan Dong, M. Wade, Andrew Williams, Alice Lee +2 more
2005Biochemical and Biophysical Research Communications - BBRC75 citations
Semantic Scholar
Bacteriophage Lambda and Plasmid lacZ Transgenic Mice for Studying Mutations in Vivo
J. Vijg, G. Douglas
199674 citations
Semantic Scholar
Databases and software for the analysis of mutations in the human p53 gene, human hprt gene and both the lacI and lacZ gene in transgenic rodents
N. F. Cariello, G. Douglas, N. Gorelick, D. W. Hart +2 more
1998Nucleic Acids Res.66 citations Open access
Semantic Scholar
Detection of induced male germline mutation: correlations and comparisons between traditional germline mutation assays, transgenic rodent assays and expanded simple tandem repeat instability assays.
Tim Singer, I. Lambert, Andrew Williams, G. Douglas +1 more
2006Mutation research54 citations
Semantic Scholar
Error-corrected Next Generation Sequencing - Promises and Challenges for Genotoxicity and Cancer Risk Assessment.
F. Marchetti, Renato Cardoso, Connie L. Chen, G. Douglas +16 more
2023Mutation research. Reviews in mutation research51 citations Open access
Semantic Scholar
The genotoxicity of mainstream and sidestream marijuana and tobacco smoke condensates.
Rebecca M. Maertens, P. White, W. Rickert, Geneviève Levasseur +6 more
2009Chemical Research in Toxicology49 citations
Semantic Scholar
A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals.
D. Kirkland, Dan D. Levy, M. J. LeBaron, M. Aardema +23 more
2019Mutation Research. Genetic Toxicology and Environmental Mutagenesis47 citations Open access
Semantic Scholar
In vivo genotoxicity testing strategies: Report from the 7th International workshop on genotoxicity testing (IWGT).
D. Kirkland, Y. Uno, M. Luijten, C. Beevers +13 more
2019Mutation research44 citations
Semantic Scholar
IPCS harmonization of methods for the prediction and quantification of human carcinogenic/mutagenic hazard, and for indicating the probable mechanism of action of carcinogens.
John Ashby, M. Waters, J. Preston, Ilse-Dore Adler +8 more
1996Mutation research41 citations
Semantic Scholar
Error-corrected next-generation sequencing to advance nonclinical genotoxicity and carcinogenicity testing
F. Marchetti, Renato Cardoso, Connie L. Chen, G. Douglas +16 more
2023Nature reviews. Drug discovery40 citations
Semantic Scholar
Mutagenic activity of 3 industrial chemicals in a battery of in vitro and in vivo tests.
D. Blakey, K. Maus, R. Bell, J. Bayley +2 more
1994Mutation research38 citations
Semantic Scholar
Genotoxicity of 3-nitrobenzanthrone and 3-aminobenzanthrone in MutaMouse and lung epithelial cells derived from MutaMouse.
V. Arlt, J. Gingerich, H. Schmeiser, D. Phillips +2 more
2008Mutagenesis37 citations Open access
Semantic Scholar
Characterisation of Muta™Mouse λgt10-lacZ transgene: evidence for in vivo rearrangements
P. Shwed, J. Crosthwait, G. Douglas, V. Seligy
2010Mutagenesis35 citations Open access
Semantic Scholar
Mutagenic and carcinogenic hazards of settled house dust. II: Salmonella mutagenicity.
Rebecca M. Maertens, R. Gagné, G. Douglas, Ji-Ping Zhu +1 more
2008Environmental Science and Technology34 citations Open access
Semantic Scholar
Human mutagens: Evidence from paternal exposure?
S. Narod, G. Douglas, Earle R. Nestmann, D. Blakey
1988Environmental and Molecular Mutagenesis34 citations
Semantic Scholar
Solvent interactions with test compounds and recommendations for testing to avoid artifacts.
Earle R. Nestmann, G. Douglas, D. Kowbel, Tina R. Harrington
1985Environmental Mutagenesis33 citations
Semantic Scholar
Sources of variability in data from a positive selection lacZ transgenic mouse mutation assay: an interlaboratory study.
W. Piegorsch, A. Lockhart, G. Carr, Barry H. Margolin +7 more
1997Mutation research30 citations
Semantic Scholar
Global transcriptional characterization of a mouse pulmonary epithelial cell line for use in genetic toxicology.
M. L. Berndt-Weis, L. Kauri, Andrew Williams, P. White +2 more
2009Toxicology in Vitro29 citations
Semantic Scholar
Analysis of gene expression in two human‐derived cell lines exposed in vitro to a 1.9 GHz pulse‐modulated radiofrequency field
V. Chauhan, Sami S. Qutob, Stephanie W Lui, A. Mariampillai +5 more
2007Proteomics29 citations
Semantic Scholar
Follow-up testing of rodent carcinogens not positive in the standard genotoxicity testing battery: IWGT workgroup report.
P. Kasper, Y. Uno, R. J. Mauthe, N. Asano +7 more
2007Mutation research29 citations
Semantic Scholar
Harnessing genomics to identify environmental determinants of heritable disease
C. Yauk, J. Lucas Argueso, S. Auerbach, P. Awadalla +25 more
2012Mutation research28 citations Open access
Semantic Scholar
Transgenic Rodent Assay for Quantifying Male Germ Cell Mutant Frequency
J. O'Brien, Marc A. Beal, J. Gingerich, L. M. Soper +3 more
2014Journal of Visualized Experiments26 citations Open access
Semantic Scholar
Cytogenetic mapping of λgt10 lacZ sequences in the transgenic mouse strain 40.6 (MutaTMMouse)
D. Blakey, G. Douglas, Kathy Huang, H. Winter
199526 citations
Semantic Scholar
Strategies in case of positive in vivo results in genotoxicity testing.
V. Thybaud, J. T. Macgregor, L. Müller, R. Crebelli +12 more
2011Mutation research25 citations
Semantic Scholar
International Commission for Protection against Environmental Mutagens and Carcinogens. ICPEMC working paper No. 5. Genotoxicity tests as predictors of carcinogens: an analysis.
G. Douglas, D. Blakey, D. Clayson
1988Mutation research25 citations
Semantic Scholar
Transgenic Rodent Gene Mutation Assay in Somatic Tissues
J. Gingerich, L. M. Soper, C. Lemieux, F. Marchetti +1 more
201424 citations
Semantic Scholar
Hepatic gene expression changes in hypothyroid juvenile mice: characterization of a novel negative thyroid-responsive element.
Hongyan Dong, C. Yauk, Andrew Williams, Alice Lee +2 more
2007Endocrinology24 citations Open access
Semantic Scholar
Assessing the Quality and Making Appropriate Use of Historical Negative Control Data: A Report of the International Workshop on Genotoxicity Testing (IWGT)
S. Dertinger, Ding-Zhou Li, C. Beevers, G. Douglas +9 more
2023Environmental and Molecular Mutagenesis22 citations Open access
Semantic Scholar
Identifying germ cell mutagens using OECD test guideline 488 (transgenic rodent somatic and germ cell gene mutation assays) and integration with somatic cell testing.
F. Marchetti, M. Aardema, C. Beevers, J. van Benthem +5 more
2018Mutation Research. Genetic Toxicology and Environmental Mutagenesis22 citations Open access
Semantic Scholar
Simulation of mouse and rat spermatogenesis to inform genotoxicity testing using OECD test guideline 488.
F. Marchetti, M. Aardema, C. Beevers, J. van Benthem +5 more
2018Mutation Research. Genetic Toxicology and Environmental Mutagenesis22 citations Open access
Semantic Scholar
A Return to the Origin of the EMGS: Rejuvenating the Quest for Human Germ Cell Mutagens and Determining the Risk to Future Generations
F. Marchetti, G. Douglas, C. Yauk
2020Environmental and Molecular Mutagenesis21 citations Open access
Semantic Scholar
Mutagenicity and chemical analysis of sequential organic extracts of airborne particulates.
S. Savard, R. Otson, G. Douglas
1992Mutation research21 citations
Semantic Scholar
Contribution of chlorination to the mutagenic activity of drinking water extracts in Salmonella and Chinese hamster ovary cells.
G. Douglas, E. R. Nestmann, G. Lebel
1986Environmental Health Perspectives21 citations Open access
Semantic Scholar
Epithelial and fibroblast cell lines cultured from the transgenic BigBlue rat: an in vitro mutagenesis assay.
Heather McDiarmid, G. Douglas, B. Coomber, P. Josephy
2001Mutation research19 citations
Semantic Scholar
In utero Exposure to Genotoxicants Leading to Genetic Mosaicism: An Overlooked Window of Susceptibility in Genetic Toxicology Testing?
R. Godschalk, C. Yauk, J. van Benthem, G. Douglas +1 more
2019Environmental and Molecular Mutagenesis18 citations Open access
Semantic Scholar
Sublinear response in lacZ mutant frequency of Muta™Mouse spermatogonial stem cells after low dose subchronic exposure to N‐ethyl‐N‐nitrosourea
J. O'Brien, M. Walker, A. Sivathayalan, G. Douglas +2 more
2015Environmental and Molecular Mutagenesis18 citations Open access
Semantic Scholar
Suitable top concentration for tests with mammalian cells: mouse lymphoma assay workgroup.
M. Moore, M. Honma, J. Clements, T. Awogi +8 more
2011Mutation research17 citations
Semantic Scholar

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