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Andrew Williams · SciRah

Researcher profile · Semantic Scholar

Andrew Williams

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Andrew Williams — researcher profile on SciRah

h-index: 50
Works: 155
Citations: 6,139

Most-cited papers

MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs.
S. S. Poulsen, A. Saber, Andrew Williams, O. Andersen +16 more
2015Toxicology and Applied Pharmacology179 citations Open access
Semantic Scholar
Recommended approaches in the application of toxicogenomics to derive points of departure for chemical risk assessment
Reza Farmahin, Andrew Williams, B. Kuo, N. Chepelev +6 more
2016Archives of Toxicology175 citations Open access
Semantic Scholar
Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[a]pyrene in drinking water
I. Moffat, N. Chepelev, S. Labib, J. Bourdon-Lacombe +13 more
2015Critical Reviews in Toxicology137 citations Open access
Semantic Scholar
Efferocytosis produces a prometastatic landscape during postpartum mammary gland involution.
Jamie C. Stanford, C. Young, D. Hicks, P. Owens +10 more
2014Journal of Clinical Investigation135 citations Open access
Semantic Scholar
Nano-risk Science: application of toxicogenomics in an adverse outcome pathway framework for risk assessment of multi-walled carbon nanotubes
S. Labib, Andrew Williams, C. Yauk, Jake K. Nikota +3 more
2015Particle and Fibre Toxicology123 citations Open access
Semantic Scholar
Intratracheally instilled titanium dioxide nanoparticles translocate to heart and liver and activate complement cascade in the heart of C57BL/6 mice
M. Husain, Dong-Mei Wu, A. Saber, N. Decan +6 more
2015Nanotoxicology110 citations Open access
Semantic Scholar
High-Throughput Transcriptomic Analysis of Human Primary Hepatocyte Spheroids Exposed to Per- and Polyfluoroalkyl Substances as a Platform for Relative Potency Characterization
A. Rowan-Carroll, A. Reardon, K. Leingartner, R. Gagné +11 more
2021Toxicological Sciences89 citations Open access
Semantic Scholar
Development and validation of a high-throughput transcriptomic biomarker to address 21st century genetic toxicology needs
Heng-Hong Li, Ren-Xiang Chen, D. Hyduke, Andrew Williams +6 more
2017Proceedings of the National Academy of Sciences of the United States of America89 citations Open access
Semantic Scholar
Tris(1,3-dichloro-2-propyl) phosphate perturbs the expression of genes involved in immune response and lipid and steroid metabolism in chicken embryos.
Amani Farhat, Julie K. Buick, Andrew Williams, C. Yauk +5 more
2014Toxicology and Applied Pharmacology89 citations
Semantic Scholar
Multi-walled carbon nanotube-induced genotoxic, inflammatory and pro-fibrotic responses in mice: Investigating the mechanisms of pulmonary carcinogenesis.
Luna Rahman, N. Jacobsen, S. Aziz, Dong-Mei Wu +6 more
2017Mutation research84 citations Open access
Semantic Scholar
Gender differences in murine pulmonary responses elicited by cellulose nanocrystals
A. Shvedova, E. Kisin, N. Yanamala, M. Farcas +9 more
2015Particle and Fibre Toxicology80 citations Open access
Semantic Scholar
A Transformative Vision for an Omics-Based Regulatory Chemical Testing Paradigm
K. Johnson, S. Auerbach, Tina Stevens, T. Barton-Maclaren +12 more
2022Toxicological Sciences78 citations Open access
Semantic Scholar
Changes in cholesterol homeostasis and acute phase response link pulmonary exposure to multi-walled carbon nanotubes to risk of cardiovascular disease.
S. S. Poulsen, A. Saber, A. Mortensen, J. Szarek +8 more
2015Toxicology and Applied Pharmacology72 citations Open access
Semantic Scholar
Case study on the utility of hepatic global gene expression profiling in the risk assessment of the carcinogen furan.
A. F. Jackson, Andrew Williams, L. Recio, M. Waters +2 more
2014Toxicology and Applied Pharmacology71 citations Open access
Semantic Scholar
Ozone Inhalation Provokes Glucocorticoid-Dependent and -Independent Effects on Inflammatory and Metabolic Pathways
Errol M. Thomson, S. Pal, J. Guénette, M. Wade +4 more
2016Toxicological Sciences68 citations Open access
Semantic Scholar
IL-1 Receptor Regulates microRNA-135b Expression in a Negative Feedback Mechanism during Cigarette Smoke–Induced Inflammation
S. Halappanavar, Jake K. Nikota, Dong-Mei Wu, Andrew Williams +2 more
2013Journal of Immunology67 citations Open access
Semantic Scholar
Technical guide for applications of gene expression profiling in human health risk assessment of environmental chemicals
J. Bourdon-Lacombe, I. Moffat, M. Deveau, M. Husain +6 more
2015Regulatory toxicology and pharmacology : RTP66 citations Open access
Semantic Scholar
Maternal inhalation of surface-coated nanosized titanium dioxide (UV-Titan) in C57BL/6 mice: effects in prenatally exposed offspring on hepatic DNA damage and gene expression
P. Jackson, S. Halappanavar, K. Hougaard, Andrew Williams +6 more
2013Nanotoxicology65 citations Open access
Semantic Scholar
Characterization of in vitro genotoxic, cytotoxic and transcriptomic responses following exposures to amorphous silica of different sizes.
N. Decan, Dong-Mei Wu, Andrew Williams, S. Bernatchez +3 more
2016Mutation Research. Genetic Toxicology and Environmental Mutagenesis63 citations Open access
Semantic Scholar
Acute phase response and inflammation following pulmonary exposure to low doses of zinc oxide nanoparticles in mice
N. Hadrup, Feriel Rahmani, N. Jacobsen, A. Saber +6 more
2019Nanotoxicology58 citations Open access
Semantic Scholar
In vitro toxicoproteomic analysis of A549 human lung epithelial cells exposed to urban air particulate matter and its water-soluble and insoluble fractions
N. Vuong, D. Breznan, P. Goegan, Julie S. O'Brien +4 more
2017Particle and Fibre Toxicology57 citations Open access
Semantic Scholar
Transcriptional profiling reveals gene expression changes associated with inflammation and cell proliferation following short‐term inhalation exposure to copper oxide nanoparticles
Pedro M Costa, I. Gosens, Andrew Williams, L. Farcal +6 more
2018Journal of Applied Toxicology56 citations Open access
Semantic Scholar
Toxicogenomic assessment of liver responses following subchronic exposure to furan in Fischer F344 rats
Hongyan Dong, S. Gill, I. Curran, Andrew Williams +3 more
2015Archives of Toxicology56 citations Open access
Semantic Scholar
Meta-analysis of transcriptomic responses as a means to identify pulmonary disease outcomes for engineered nanomaterials
Jake K. Nikota, Andrew Williams, C. Yauk, H. Wallin +2 more
2015Particle and Fibre Toxicology55 citations Open access
Semantic Scholar
ErbB3 downregulation enhances luminal breast tumor response to antiestrogens.
Meghan M. Morrison, K. Hutchinson, M. Williams, Jamie C. Stanford +12 more
2013Journal of Clinical Investigation53 citations Open access
Semantic Scholar
Integration of metabolic activation with a predictive toxicogenomics signature to classify genotoxic versus nongenotoxic chemicals in human TK6 cells
Julie K. Buick, I. Moffat, Andrew Williams, C. Swartz +6 more
2015Environmental and Molecular Mutagenesis52 citations Open access
Semantic Scholar
Application of biclustering of gene expression data and gene set enrichment analysis methods to identify potentially disease causing nanomaterials
Andrew Williams, S. Halappanavar
2015Beilstein Journal of Nanotechnology52 citations Open access
Semantic Scholar
Identification of mechanisms of action of bisphenol a‐induced human preadipocyte differentiation by transcriptional profiling
Jonathan G. Boucher, M. Husain, A. Rowan-Carroll, Andrew Williams +2 more
2014Obesity52 citations Open access
Semantic Scholar
Impact of Cigarette Smoke on the Human and Mouse Lungs: A Gene-Expression Comparison Study
Mathieu C. Morissette, M. Lamontagne, Jean‐Christophe Bérubé, Gordon J. Gaschler +9 more
2014PLoS ONE51 citations Open access
Semantic Scholar
Duplex sequencing identifies genomic features that determine susceptibility to benzo(a)pyrene-induced in vivo mutations
D. LeBlanc, M. Meier, Fang Y. Lo, Elizabeth K. Schmidt +5 more
2022BMC Genomics50 citations Open access
Semantic Scholar
Hepatic miRNA profiles and thyroid hormone homeostasis in rats exposed to dietary potassium perfluorooctanesulfonate (PFOS).
Hongyan Dong, I. Curran, Andrew Williams, G. Bondy +2 more
2016Environmental Toxicology and Pharmacology50 citations
Semantic Scholar
Impact of Genomics Platform and Statistical Filtering on Transcriptional Benchmark Doses (BMD) and Multiple Approaches for Selection of Chemical Point of Departure (PoD)
A. F. Webster, N. Chepelev, R. Gagné, B. Kuo +3 more
2015PLoS ONE50 citations Open access
Semantic Scholar
Integrating toxicogenomics into human health risk assessment: Lessons learned from the benzo[a]pyrene case study
N. Chepelev, I. Moffat, S. Labib, J. Bourdon-Lacombe +7 more
2015Critical Reviews in Toxicology50 citations
Semantic Scholar
Stat-6 signaling pathway and not Interleukin-1 mediates multi-walled carbon nanotube-induced lung fibrosis in mice: insights from an adverse outcome pathway framework
Jake K. Nikota, Allyson Banville, L. Goodwin, Dong-Mei Wu +5 more
2017Particle and Fibre Toxicology48 citations Open access
Semantic Scholar
Mapping Indicators of Toxicity for Polycyclic Aromatic Compounds in the Atmosphere of the Athabasca Oil Sands Region.
N. Jariyasopit, T. Harner, Dong-Mei Wu, Andrew Williams +2 more
2016Environmental Science and Technology48 citations Open access
Semantic Scholar
A comparison of transgenic rodent mutation and in vivo comet assay responses for 91 chemicals.
D. Kirkland, Dan D. Levy, M. J. LeBaron, M. Aardema +23 more
2019Mutation Research. Genetic Toxicology and Environmental Mutagenesis47 citations Open access
Semantic Scholar
A Modern Genotoxicity Testing Paradigm: Integration of the High-Throughput CometChip® and the TGx-DDI Transcriptomic Biomarker in Human HepaRG™ Cell Cultures
Julie K. Buick, Andrew Williams, M. Meier, C. Swartz +5 more
2021Frontiers in Public Health45 citations Open access
Semantic Scholar
In vivo genotoxicity testing strategies: Report from the 7th International workshop on genotoxicity testing (IWGT).
D. Kirkland, Y. Uno, M. Luijten, C. Beevers +13 more
2019Mutation research44 citations
Semantic Scholar
Characterizing Benzo[a]pyrene-induced lacZ mutation spectrum in transgenic mice using next-generation sequencing
Marc A. Beal, R. Gagné, Andrew Williams, F. Marchetti +1 more
2015BMC Genomics44 citations Open access
Semantic Scholar
TGx-DDI, a Transcriptomic Biomarker for Genotoxicity Hazard Assessment of Pharmaceuticals and Environmental Chemicals
Heng-Hong Li, C. Yauk, Ren-Xiang Chen, D. Hyduke +6 more
2019Frontiers in Big Data41 citations Open access
Semantic Scholar
Proteomic changes in human lung epithelial cells (A549) in response to carbon black and titanium dioxide exposures.
N. Vuong, P. Goegan, Susantha Mohottalage, D. Breznan +6 more
2016Journal of Proteomics39 citations Open access
Semantic Scholar
Application of the TGx‐28.65 transcriptomic biomarker to classify genotoxic and non‐genotoxic chemicals in human TK6 cells in the presence of rat liver S9
C. Yauk, Julie K. Buick, Andrew Williams, C. Swartz +5 more
2016Environmental and Molecular Mutagenesis39 citations Open access
Semantic Scholar
Assessment of the performance of the TGx‐DDI biomarker to detect DNA damage‐inducing agents using quantitative RT‐PCR in TK6 cells
E. Cho, Julie K. Buick, Andrew Williams, Ren-Xiang Chen +5 more
2018Environmental and Molecular Mutagenesis37 citations Open access
Semantic Scholar
Using a gene expression biomarker to identify DNA damage‐inducing agents in microarray profiles
J. Corton, Andrew Williams, C. Yauk
2018Environmental and Molecular Mutagenesis37 citations Open access
Semantic Scholar
Flow cytometric micronucleus assay and TGx-DDI transcriptomic biomarker analysis of ten genotoxic and non-genotoxic chemicals in human HepaRG™ cells
Julie K. Buick, Andrew Williams, R. Gagné, C. Swartz +3 more
2020Genes and Environment36 citations Open access
Semantic Scholar
Ranking of nanomaterial potency to induce pathway perturbations associated with lung responses
S. Halappanavar, Luna Rahman, Jake K. Nikota, S. S. Poulsen +6 more
2019NanoImpact35 citations Open access
Semantic Scholar
Mining the Archives: A Cross-Platform Analysis of Gene Expression Profiles in Archival Formalin-Fixed Paraffin-Embedded Tissues
A. F. Webster, P. Zumbo, J. Fostel, J. Gandara +6 more
2015Toxicological Sciences34 citations Open access
Semantic Scholar
A transcriptomic overview of lung and liver changes one day after pulmonary exposure to graphene and graphene oxide.
S. S. Poulsen, S. Bengtson, Andrew Williams, N. Jacobsen +3 more
2020Toxicology and Applied Pharmacology32 citations Open access
Semantic Scholar
Ozone increases plasma kynurenine-tryptophan ratio and impacts hippocampal serotonin receptor and neurotrophic factor expression: Role of stress hormones.
Mercedes Rose, Alain Filiatreault, J. Guénette, Andrew Williams +1 more
2020Environmental Research30 citations Open access
Semantic Scholar
Hepatic transcriptional dose-response analysis of male and female Fischer rats exposed to hexabromocyclododecane.
Reza Farmahin, A. Gannon, R. Gagné, A. Rowan-Carroll +4 more
2019Food and Chemical Toxicology30 citations Open access
Semantic Scholar

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