Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

H. Schmeiser · SciRah

Researcher profile · Semantic Scholar

H. Schmeiser

Share profile

H. Schmeiser — researcher profile on SciRah

h-index: 61
Works: 237
Citations: 10K

Most-cited papers

The Epidemiology, Diagnosis, and Management of Aristolochic Acid Nephropathy
M. Gökmen, J. Cosyns, V. Arlt, M. Stiborová +7 more
2013Annals of Internal Medicine124 citations
Semantic Scholar
Balkan endemic nephropathy: an update on its aetiology
M. Stiborová, V. Arlt, H. Schmeiser
2016Archives of Toxicology123 citations Open access
Semantic Scholar
Exceptionally long‐term persistence of DNA adducts formed by carcinogenic aristolochic acid I in renal tissue from patients with aristolochic acid nephropathy
H. Schmeiser, J. Nortier, Rajinder Singh, G. Gamboa da Costa +8 more
2014International Journal of Cancer103 citations Open access
Semantic Scholar
Chemical and molecular basis of the carcinogenicity of Aristolochia plants.
H. Schmeiser, M. Stiborová, V. Arlt
2009Current opinion in drug discovery & development97 citations
Semantic Scholar
DNA Adducts Formed by Aristolochic Acid Are Unique Biomarkers of Exposure and Explain the Initiation Phase of Upper Urothelial Cancer
M. Stiborová, V. Arlt, H. Schmeiser
2017International Journal of Molecular Sciences92 citations Open access
Semantic Scholar
Aristolochic acid mutagenesis: molecular clues to the aetiology of Balkan endemic nephropathy-associated urothelial cancer.
V. Arlt, M. Stiborová, Jochen vom Brocke, M. Simões +5 more
2009Carcinogenesis87 citations
Semantic Scholar
The impact of individual cytochrome P450 enzymes on oxidative metabolism of benzo[a]pyrene in human livers
M. Sulc, R. Indra, Michaela Moserová, H. Schmeiser +4 more
2016Environmental and Molecular Mutagenesis73 citations Open access
Semantic Scholar
Bioactivation versus detoxication of the urothelial carcinogen aristolochic acid I by human cytochrome P450 1A1 and 1A2.
M. Stiborová, K. Levova, F. Bárta, Zhan-Quan Shi +5 more
2012Toxicological Sciences73 citations Open access
Semantic Scholar
³²P-postlabeling analysis of DNA adducts.
H. Schmeiser, M. Stiborová, V. Arlt
2013Methods in molecular biology72 citations
Semantic Scholar
Evidence of exposure to aristolochic acid in patients with urothelial cancer from a Balkan endemic nephropathy region of Romania
H. Schmeiser, J. Kucab, V. Arlt, David H. Phillips +7 more
2012Environmental and Molecular Mutagenesis64 citations
Semantic Scholar
Role of cytochromes P450 1A1/2 in detoxication and activation of carcinogenic aristolochic acid I: studies with the hepatic NADPH:cytochrome P450 reductase null (HRN) mouse model.
K. Levova, Michaela Moserová, V. Kotrbová, M. Sulc +8 more
2011Toxicological Sciences63 citations Open access
Semantic Scholar
The human carcinogen aristolochic acid i is activated to form DNA adducts by human NAD(P)H:quinone oxidoreductase without the contribution of acetyltransferases or sulfotransferases
M. Stiborová, Jaroslav Mareîs, E. Frei, V. Arlt +2 more
2011Environmental and Molecular Mutagenesis59 citations
Semantic Scholar
Enzymes metabolizing aristolochic acid and their contribution to the development of aristolochic acid nephropathy and urothelial cancer.
M. Stiborová, Václav Martínek, E. Frei, V. Arlt +1 more
2013Current drug metabolism57 citations
Semantic Scholar
Cytochrome b5 and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions.
M. Stiborová, Michaela Moserová, V. Černá, R. Indra +8 more
2014Toxicology52 citations Open access
Semantic Scholar
Gene expression changes induced by the human carcinogen aristolochic acid I in renal and hepatic tissue of mice
V. Arlt, J. Zuo, K. Trenz, C. Roufosse +5 more
2011International Journal of Cancer51 citations
Semantic Scholar
The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/–) and Trp53(−/−) mice
A. Krais, E. Speksnijder, Joost P. M. Melis, R. Indra +10 more
2015Archives of Toxicology47 citations Open access
Semantic Scholar
Role of P450 1A1 and P450 1A2 in bioactivation versus detoxication of the renal carcinogen aristolochic acid I: studies in Cyp1a1-/-, Cyp1a2-/-, and Cyp1a1/1a2-/- mice.
V. Arlt, K. Levova, F. Bárta, Zhan-Quan Shi +6 more
2011Chemical Research in Toxicology47 citations
Semantic Scholar
Genomic N6‐methyladenine determination by MEKC with LIF
Annette M. Krais, Michael G. Cornelius, H. Schmeiser
2010Electrophoresis47 citations
Semantic Scholar
TP53 mutations induced by BPDE in Xpa-WT and Xpa-Null human TP53 knock-in (Hupki) mouse embryo fibroblasts
J. Kucab, H. van Steeg, M. Luijten, H. Schmeiser +3 more
2015Mutation research43 citations Open access
Semantic Scholar
Mechanisms of the different DNA adduct forming potentials of the urban air pollutants 2-nitrobenzanthrone and carcinogenic 3-nitrobenzanthrone.
M. Stiborová, Václav Martínek, Martina Svobodová, J. Sístková +7 more
2010Chemical Research in Toxicology43 citations
Semantic Scholar
NADH:Cytochrome b5 Reductase and Cytochrome b5 Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a]pyrene
M. Stiborová, R. Indra, Michaela Moserová, E. Frei +4 more
2016Chemical Research in Toxicology40 citations Open access
Semantic Scholar
Mechanisms of Enzyme-Catalyzed Reduction of Two Carcinogenic Nitro-Aromatics, 3-Nitrobenzanthrone and Aristolochic Acid I: Experimental and Theoretical Approaches
M. Stiborová, E. Frei, H. Schmeiser, V. Arlt +1 more
2014International Journal of Molecular Sciences39 citations Open access
Semantic Scholar
Aristolochic acid nephropathy revisited: a place for innate and adaptive immunity?
A. Pozdzik, A. Berton, H. Schmeiser, W. Missoum +4 more
2010Histopathology38 citations Open access
Semantic Scholar
The carcinogenic air pollutant 3-nitrobenzanthrone induces GC to TA transversion mutations in human p53 sequences.
Jochen vom Brocke, A. Krais, C. Whibley, M. Hollstein +1 more
2008Mutagenesis38 citations
Semantic Scholar
A Mechanism of O-Demethylation of Aristolochic Acid I by Cytochromes P450 and Their Contributions to This Reaction in Human and Rat Livers: Experimental and Theoretical Approaches
M. Stiborová, F. Bárta, K. Levova, P. Hodek +3 more
2015International Journal of Molecular Sciences37 citations Open access
Semantic Scholar
Gene expression profiles modulated by the human carcinogen aristolochic acid I in human cancer cells and their dependence on TP53.
M. Simões, S. Hockley, T. Schwerdtle, G. Gamboa da Costa +3 more
2008Toxicology and Applied Pharmacology37 citations Open access
Semantic Scholar
The environmental pollutant and carcinogen 3-nitrobenzanthrone induces cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase in rat lung and kidney, thereby enhancing its own genotoxicity.
M. Stiborová, H. Dračínská, Jana Mizerovská, E. Frei +5 more
2008Toxicology37 citations Open access
Semantic Scholar
Knockout and humanized mice as suitable tools to identify enzymes metabolizing the human carcinogen aristolochic acid
M. Stiborová, E. Frei, V. Arlt, H. Schmeiser
2014Xenobiotica; the fate of foreign compounds in biological systems35 citations
Semantic Scholar
Cytochrome b5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b5/P450 reductase null (HBRN) mice
Lindsay Reed, Iveta Mrízová, F. Bárta, R. Indra +8 more
2018Archives of Toxicology34 citations Open access
Semantic Scholar
Determination of genomic 5-hydroxymethyl-2’-deoxycytidine in human DNA by capillary electrophoresis with laser induced fluorescence
A. Krais, Y. Park, C. Plass, H. Schmeiser
2011Epigenetics34 citations Open access
Semantic Scholar
Comparative transcriptomic analyses to scrutinize the assumption that genotoxic PAHs exert effects via a common mode of action
S. Labib, Andrew Williams, Charles Guo, K. Leingartner +5 more
2015Archives of Toxicology33 citations Open access
Semantic Scholar
3-Nitrobenzanthrone and 3-aminobenzanthrone induce DNA damage and cell signalling in Hepa1c1c7 cells.
N. Landvik, V. Arlt, E. Nagy, A. Solhaug +6 more
2010Mutation research32 citations
Semantic Scholar
Human cytochromes P450 1A1 and 1A2 participate in detoxication of carcinogenic aristolochic acid.
J. Sístková, J. Hudeček, P. Hodek, E. Frei +2 more
2008Neuro - endocrinology letters31 citations
Semantic Scholar
Induced expression of cytochrome P450 1A and NAD(P)H:quinone oxidoreductase determined at mRNA, protein, and enzyme activity levels in rats exposed to the carcinogenic azo dye 1-phenylazo-2-naphthol (Sudan I).
M. Stiborová, H. Dračínská, Václav Martínek, Dagmar Svášková +6 more
2013Chemical Research in Toxicology29 citations
Semantic Scholar
Induction of biotransformation enzymes by the carcinogenic air-pollutant 3-nitrobenzanthrone in liver, kidney and lung, after intra-tracheal instillation in rats.
Jana Mizerovská, H. Dračínská, E. Frei, H. Schmeiser +2 more
2011Mutation research28 citations Open access
Semantic Scholar
The influence of ochratoxin A on DNA adduct formation by the carcinogen aristolochic acid in rats
M. Stiborová, F. Bárta, K. Levova, P. Hodek +3 more
2014Archives of Toxicology27 citations
Semantic Scholar
Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone
V. Arlt, W. Meinl, S. Florian, E. Nagy +12 more
2016Archives of Toxicology26 citations Open access
Semantic Scholar
Induction of cytochromes P450 1A1 and 1A2 suppresses formation of DNA adducts by carcinogenic aristolochic acid I in rats in vivo
H. Dračínská, F. Bárta, K. Levova, A. Hudecová +6 more
2016Toxicology26 citations Open access
Semantic Scholar
Bacillus Calmette‐Guerin therapy in non‐muscle‐invasive bladder carcinoma after renal transplantation for end‐stage aristolochic acid nephropathy
T. Roumeguère, Nilufer Broeders, Avinash Jayaswal, S. Rorive +5 more
2015Transplant International26 citations
Semantic Scholar
NAD(P)H:quinone oxidoreductase expression in Cyp1a-knockout and CYP1A-humanized mouse lines and its effect on bioactivation of the carcinogen aristolochic acid I.
K. Levova, Michaela Moserová, D. Nebert, D. Phillips +4 more
2012Toxicology and Applied Pharmacology26 citations Open access
Semantic Scholar
The role of biotransformation enzymes in the development of renal injury and urothelial cancer caused by aristolochic acid: urgent questions and difficult answers.
M. Stiborová, E. Frei, V. Arlt, H. Schmeiser
2009Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia26 citations Open access
Semantic Scholar
Comparison of activation of aristolochic acid I and II with NADPH:quinone oxidoreductase, sulphotransferases and N-acetyltranferases.
Václav Martínek, B. Kubíĉková, V. Arlt, E. Frei +3 more
2011Neuro - endocrinology letters25 citations
Semantic Scholar
Upper urinary tract urothelial cancers: where it is A:T
M. Olivier, M. Hollstein, H. Schmeiser, K. Straif +1 more
2012Nature Reviews. Cancer24 citations
Semantic Scholar
Quantification of 3-nitrobenzanthrone-DNA adducts using online column-switching HPLC-electrospray tandem mass spectrometry.
G. Gamboa da Costa, Rajinder Singh, V. Arlt, Amin Mirza +5 more
2009Chemical Research in Toxicology24 citations
Semantic Scholar
The Histone Deacetylase Inhibitor Valproic Acid Exerts a Synergistic Cytotoxicity with the DNA-Damaging Drug Ellipticine in Neuroblastoma Cells
T. Černá, J. Hraběta, T. Eckschlager, E. Frei +3 more
2018International Journal of Molecular Sciences22 citations Open access
Semantic Scholar
The influence of dicoumarol on the bioactivation of the carcinogen aristolochic acid I in rats.
M. Stiborová, K. Levova, F. Bárta, M. Sulc +3 more
2014Mutagenesis22 citations Open access
Semantic Scholar
The effect of aristolochic acid I on expression of NAD(P)H:quinone oxidoreductase in mice and rats--a comparative study.
F. Bárta, K. Levova, E. Frei, H. Schmeiser +2 more
2014Mutation Research. Genetic Toxicology and Environmental Mutagenesis22 citations Open access
Semantic Scholar
Rat cytochromes P450 oxidize 3-aminobenzanthrone, a human metabolite of the carcinogenic environmental pollutant 3-nitrobenzanthrone
Jana Mizerovská, H. Dračínská, V. Arlt, J. Hudeček +4 more
2008Interdisciplinary Toxicology21 citations Open access
Semantic Scholar
Co-Exposure to Aristolochic Acids I and II Increases DNA Adduct Formation Responsible for Aristolochic Acid I-Mediated Carcinogenicity in Rats
F. Bárta, Alena Dedı́ková, Michaela Bebová, Š. Dušková +5 more
2021International Journal of Molecular Sciences20 citations Open access
Semantic Scholar
Enzymes oxidizing the azo dye 1-phenylazo-2-naphthol (Sudan I) and their contribution to its genotoxicity and carcinogenicity.
M. Stiborová, H. Schmeiser, E. Frei, P. Hodek +1 more
2015Current drug metabolism20 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

V. Arlt×41
Invite
V. Arlt — researcher profile on SciRah
M. Stiborová×37
Invite
M. Stiborová — researcher profile on SciRah
E. Frei×25
Invite
E. Frei — researcher profile on SciRah
D. Phillips×13
Invite
D. Phillips — researcher profile on SciRah

×10

Invite

F. Bárta — researcher profile on SciRah

Invite

K. Levova — researcher profile on SciRah

Michaela Moserová×8

Invite

Michaela Moserová — researcher profile on SciRah

Václav Martínek×8

Invite

Václav Martínek — researcher profile on SciRah

Invite

P. Hodek — researcher profile on SciRah

Invite

J. Nortier — researcher profile on SciRah

M. Hollstein×5

Invite

M. Hollstein — researcher profile on SciRah

Invite

R. Indra — researcher profile on SciRah