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Ding-Zhou Li · SciRah

Researcher profile · Semantic Scholar

Ding-Zhou Li

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Ding-Zhou Li — researcher profile on SciRah

h-index: 14
Works: 40
Citations: 1,362

Most-cited papers

The effect of plasma protein binding on in vivo efficacy: misconceptions in drug discovery
Dennis A. Smith, Ding-Zhou Li, E. Kerns
2010Nature reviews. Drug discovery839 citations
Semantic Scholar
Assessment of serum bile acid profiles as biomarkers of liver injury and liver disease in humans
Lina Luo, J. Aubrecht, Ding-Zhou Li, R. Warner +3 more
2018PLoS ONE144 citations Open access
Semantic Scholar
Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells
James W. Kramer, H. Himmel, A. Lindqvist, S. Stoelzle-Feix +18 more
2020Scientific Reports56 citations Open access
Semantic Scholar
Development and validation of an in vitro micronucleus assay platform in TK6 cells.
Z. Sobol, M. Homiski, Donna A. Dickinson, R. Spellman +9 more
2012Mutation research36 citations
Semantic Scholar
Best practice considerations for nonclinical in vivo cardiovascular telemetry studies in non-rodent species: Delivering high quality QTc data to support ICH E14/S7B Q&As.
E. Rossman, Todd A. Wisialowski, H. Vargas, J. Valentin +13 more
2023Journal of pharmacological and toxicological methods31 citations
Semantic Scholar
Seizure prediction using scalp electroencephalogram.
I. Drury, Brien Smith, Ding-Zhou Li, R. Savit
2003Experimental Neurology29 citations
Semantic Scholar
Assessing the Quality and Making Appropriate Use of Historical Negative Control Data: A Report of the International Workshop on Genotoxicity Testing (IWGT)
S. Dertinger, Ding-Zhou Li, C. Beevers, G. Douglas +9 more
2023Environmental and Molecular Mutagenesis22 citations Open access
Semantic Scholar
Biology and postnatal development of organ systems of cynomolgus monkeys (Macaca fascicularis)
Xian-Tang Li, Rosemary Santos, Jan Bernal, Ding-Zhou Li +2 more
2022Journal of medical primatology22 citations Open access
Semantic Scholar
Age‐ and sex‐related changes in body weights and clinical pathology analytes in cynomolgus monkeys (Macaca Fascicularis) of Mauritius origin
Xian-Tang Li, Ding-Zhou Li, Kathleen E. Biddle, S. Portugal +4 more
2022Veterinary clinical pathology18 citations Open access
Semantic Scholar
Preclinical to Clinical Translation of Hemodynamic Effects in Cardiovascular Safety Pharmacology Studies.
Siddharth Bhatt, Carrie A. Northcott, Todd A. Wisialowski, Ding-Zhou Li +1 more
2019Toxicological Sciences17 citations Open access
Semantic Scholar
Recommendations to qualify biomarker candidates of drug-induced liver injury.
J. Ozer, R. Chetty, G. Kenna, N. Koppiker +6 more
2010Biomarkers in Medicine17 citations
Semantic Scholar
Non-linear, non-invasive method for seizure anticipation in focal epilepsy.
Ding-Zhou Li, Wei-Ping Zhou, I. Drury, R. Savit
2003Mathematical Biosciences17 citations
Semantic Scholar
Characterization of a high throughput human stem cell cardiomyocyte assay to predict drug-induced changes in clinical electrocardiogram parameters.
Peter Kilfoil, Shuyun Feng, Asser Bassyouni, Tiffany Lee +6 more
2021European Journal of Pharmacology14 citations Open access
Semantic Scholar
Understanding Dynamic State Changes in Temporal Lobe Epilepsy
R. Savit, Ding-Zhou Li, Wei-Ping Zhou, I. Drury
2001Journal of clinical neurophysiology14 citations
Semantic Scholar
Statistical power analysis of cardiovascular safety pharmacology studies in conscious rats.
Siddharth Bhatt, Ding-Zhou Li, Declan Flynn, Todd A. Wisialowski +2 more
2016Journal of pharmacological and toxicological methods10 citations
Semantic Scholar
Measuring T-cell responses against LCV and CMV in cynomolgus macaques using ELISPOT: Potential application to non-clinical testing of immunomodulatory therapeutics
Cris Kamperschroer, L. O’Donnell, Patricia A. Schneider, Ding-Zhou Li +3 more
2014Journal of Immunotoxicology10 citations Open access
Semantic Scholar
Consideration of the unbound drug concentration in enzyme kinetics.
N. Waters, R. Obach, Ding-Zhou Li
2014Methods in molecular biology10 citations
Semantic Scholar
Linear and Nonlinear Measures and Seizure Anticipation in Temporal Lobe Epilepsy
Ding-Zhou Li, Wei-Ping Zhou, I. Drury, R. Savit
2003Journal of Computational Neuroscience10 citations Open access
Semantic Scholar
Development and partial validation of a mouse model for predicting drug hypersensitivity reactions
Jessica Whritenour, S. Cole, X. Zhu, Ding-Zhou Li +1 more
2014Journal of Immunotoxicology8 citations Open access
Semantic Scholar
Nonclinical species sensitivity to convulsions: An IQ DruSafe consortium working group initiative.
Jamie K. DaSilva, L. Breidenbach, Tracy Deats, Ding-Zhou Li +6 more
2020Journal of pharmacological and toxicological methods7 citations
Semantic Scholar
Heartbeat dynamics in adrenergic blocker treated conscious beagle dogs.
Ding-Zhou Li, Alan Y. Chiang, Christine A. Clawson, B. Main +1 more
2008Journal of pharmacological and toxicological methods7 citations
Semantic Scholar
Seizure anticipation, states of consciousness and marginal predictability in temporal lobe epilepsy.
Ding-Zhou Li, Wei-Ping Zhou, I. Drury, R. Savit
2006Epilepsy Research6 citations
Semantic Scholar
Cross-company evaluation of the human lymphocyte activation assay
M. Collinge, Patricia A. Schneider, Ding-Zhou Li, Stanley T. Parish +10 more
2020Journal of Immunotoxicology5 citations Open access
Semantic Scholar
Publisher Correction: Cross-site and cross-platform variability of automated patch clamp assessments of drug effects on human cardiac currents in recombinant cells
James W. Kramer, H. Himmel, A. Lindqvist, S. Stoelzle-Feix +18 more
2020Scientific Reports3 citations Open access
Semantic Scholar
Development of a screening assay to evaluate the potential of drugs to cause immune-mediated hypersensitivity reactions
Q. You, Linling Cheng, Ding-Zhou Li, Jessica Whritenour +2 more
2014Journal of Immunotoxicology3 citations Open access
Semantic Scholar
Survey and Recommendations on the Use of P-Values Driving Decisions in Nonclinical Pharmaceutical Applications
S. Altan, D. Amaratunga, Javier Cabrera, Jeonifer M. Garren +18 more
2022Statistics in Biopharmaceutical Research2 citations
Semantic Scholar
Characterizing intra-tumor and inter-tumor variability of immune cell infiltrates in murine syngeneic tumors
S. Mojtahedzadeh, A. Opsahl, Joan-Kristel Aguilar, Ding-Zhou Li +7 more
2020bioRxiv2 citations Open access
Semantic Scholar
Reprint of: Nonclinical species sensitivity to convulsions: An IQ DruSafe consortium working group initiative.
Jamie K. DaSilva, L. Breidenbach, Tracy Deats, Ding-Zhou Li +6 more
2020Journal of pharmacological and toxicological methods2 citations
Semantic Scholar
General Toxicology, Safety Pharmacology, Reproductive Toxicology, and Juvenile Toxicology Studies
S. Bailey, Ding-Zhou Li, D. Potter
20162 citations
Semantic Scholar
Quantitative association analyses of CNS safety pharmacology parameters to clinical observations in toxicology studies.
Jamie K. DaSilva, Enoch Cobbina, Cheryl Tyszkiewicz, Ding-Zhou Li +1 more
2019Journal of pharmacological and toxicological methods1 citations
Semantic Scholar
QUANTIFYING LONG-RANGE HEART RATE VARIABILITY
Alan Y. Chiang, Ding-Zhou Li, D. Leishman
20071 citations
Semantic Scholar
Semiclassical Theory of Excitonic Polaritons in a Planar Semiconductor Microcavity
Gu Xu, Ding-Zhou Li, Bing-Shen Wang, Zhao-bin Su
19991 citations Open access
Semantic Scholar
Characterization of low-incidence cardiac arrhythmias in chaired cynomolgus monkeys and the utility of Bayesian statistics to determine a relationship to test article
Peter D. Harris, Ding-Zhou Li, Corey Petrella, Jill Nichols +2 more
2018Journal of pharmacological and toxicological methods0 citations
Semantic Scholar
Blood pressure and heart rate measures: How well do pre‐clinical models translate? (681.7)
J. Steidl-Nichols, Siddharth Bhatt, M. Hemkens, J. Heyen +5 more
20140 citations
Semantic Scholar
Characterization of CMV- and LCV-specific T cell responses and their sensitivity to immunosuppression in cynomolgus macaques (P6367)
Cris Kamperschroer, L. O’Donnell, Patricia A. Schneider, Ding-Zhou Li +1 more
2013Journal of Immunology0 citations
Semantic Scholar
Effect of chair-restraint on cardiac troponin levels in nonhuman primates
R. Barnes, Peter D. Harris, Todd A. Wisialowski, Ding-Zhou Li +3 more
20130 citations
Semantic Scholar
Validation of JET™ (Jacketed External Telemetry) technology for ECG and blood pressure assessment in the dog
S. Foote, Jacob B. Holloway, A. Foote, Peter D. Harris +4 more
20110 citations
Semantic Scholar
The use of alternate QRS measurement methods to improve detection of propafenone-induced QRS prolongation
Peter D. Harris, S. Foote, Ding-Zhou Li, B. Fermini +1 more
20110 citations
Semantic Scholar
Statistical considerations on the power of cardiovascular safety pharmacology studies
Ding-Zhou Li
20100 citations
Semantic Scholar
Nonlinear times series analysis of epileptic human electroencephalogram (EEG)
Ding-Zhou Li
20050 citations
Semantic Scholar

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