Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

Silvia Franchini · SciRah

Researcher profile · Semantic Scholar

Silvia Franchini

Share profile

Silvia Franchini — researcher profile on SciRah

h-index: 20
Works: 93
Citations: 1,596

Most-cited papers

A Novel Role of Complement: Mice Deficient in the Fifth Component of Complement (C5) Exhibit Impaired Liver Regeneration1
D. Mastellos, J. Papadimitriou, Silvia Franchini, P. Tsonis +1 more
2001Journal of Immunology271 citations Open access
Semantic Scholar
Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1.
R. Reca, D. Mastellos, M. Majka, L. Marquez +8 more
2003Blood241 citations Open access
Semantic Scholar
C3a and C3b Activation Products of the Third Component of Complement (C3) Are Critical for Normal Liver Recovery after Toxic Injury1
M. Markiewski, D. Mastellos, Ruxandra Tudoran, R. Deangelis +5 more
2004Journal of Immunology178 citations Open access
Semantic Scholar
Kinetic Analysis of the Interactions of Complement Receptor 2 (CR2, CD21) with Its Ligands C3d, iC3b, and the EBV Glycoprotein gp350/2201
M. Sarrias, Silvia Franchini, G. Canziani, Emelia Argyropoulos +3 more
2001Journal of Immunology87 citations Open access
Semantic Scholar
Novel monoclonal antibodies against mouse C3 interfering with complement activation: description of fine specificity and applications to various immunoassays.
D. Mastellos, J. Prechl, G. László, K. Papp +7 more
2004Molecular Immunology71 citations
Semantic Scholar
Cloning and purification of the rainbow trout fifth component of complement (C5).
Silvia Franchini, I. Zarkadis, G. Sfyroera, A. Sahu +4 more
2000Developmental and Comparative Immunology63 citations
Semantic Scholar
Cell-Cycle Inhibition by Helicobacter pylori L-Asparaginase
C. Scotti, P. Sommi, M. Pasquetto, Donata Cappelletti +17 more
2010PLoS ONE53 citations Open access
Semantic Scholar
Further Insights Into the Pharmacology of the Human Trace Amine‐Associated Receptors: Discovery of Novel Ligands for TAAR1 by a Virtual Screening Approach
E. Cichero, S. Espinoza, Silvia Franchini, Sara Guariento +3 more
2014Chemical Biology and Drug Design38 citations Open access
Semantic Scholar
Synthesis, biological evaluation, and docking studies of tetrahydrofuran- cyclopentanone- and cyclopentanol-based ligands acting at adrenergic α₁- and serotonine 5-HT1A receptors.
A. Prandi, Silvia Franchini, Leda Ivanova Manasieva, P. Fossa +6 more
2012Journal of Medicinal Chemistry36 citations Open access
Semantic Scholar
1,2,4-Benzothiadiazine derivatives as α1 and 5-HT1A receptor ligands
A. Tait, Amedeo Luppi, Silvia Franchini, E. Preziosi +6 more
200534 citations Open access
Semantic Scholar
Synthesis, biological evaluation and molecular modeling of 1-oxa-4-thiaspiro- and 1,4-dithiaspiro[4.5]decane derivatives as potent and selective 5-HT1A receptor agonists.
Silvia Franchini, Leda Ivanova Manasieva, C. Sorbi, U. Battisti +9 more
2017European journal of medicinal chemistry33 citations Open access
Semantic Scholar
1,3-dioxolane-based ligands as a novel class of alpha1-adrenoceptor antagonists.
L. Brasili, C. Sorbi, Silvia Franchini, M. Manicardi +4 more
2003Journal of Medicinal Chemistry33 citations Open access
Semantic Scholar
1,3‐Dioxolane‐Based Ligands as Rigid Analogues of Naftopidil: Structure–Affinity/Activity Relationships at α1 and 5‐HT1A Receptors
C. Sorbi, Silvia Franchini, A. Tait, A. Prandi +6 more
2009ChemMedChem30 citations Open access
Semantic Scholar
A homology modelling-driven study leading to the discovery of the first mouse trace amine-associated receptor 5 (TAAR5) antagonists
E. Cichero, S. Espinoza, M. Tonelli, Silvia Franchini +5 more
201629 citations Open access
Semantic Scholar
Scouting new sigma receptor ligands: Synthesis, pharmacological evaluation and molecular modeling of 1,3-dioxolane-based structures and derivatives.
Silvia Franchini, U. Battisti, A. Prandi, A. Tait +9 more
2016European journal of medicinal chemistry25 citations Open access
Semantic Scholar
Novel S1R agonists counteracting NMDA excitotoxicity and oxidative stress: A step forward in the discovery of neuroprotective agents.
P. Linciano, C. Sorbi, G. Rossino, D. Rossi +10 more
2023European journal of medicinal chemistry24 citations Open access
Semantic Scholar
1,3-Dioxolane-based ligands incorporating a lactam or imide moiety: structure-affinity/activity relationship at alpha1-adrenoceptor subtypes and at 5-HT1A receptors.
Silvia Franchini, A. Prandi, A. Baraldi, C. Sorbi +8 more
2010European journal of medicinal chemistry24 citations Open access
Semantic Scholar
1,3-Dioxane as a scaffold for potent and selective 5-HT1AR agonist with in-vivo anxiolytic, anti-depressant and anti-nociceptive activity.
Silvia Franchini, C. Sorbi, P. Linciano, G. Carnevale +9 more
2019European journal of medicinal chemistry23 citations Open access
Semantic Scholar
Discovery of a new series of 5-HT1A receptor agonists.
Silvia Franchini, A. Prandi, C. Sorbi, A. Tait +7 more
2010Bioorganic & Medicinal Chemistry Letters22 citations Open access
Semantic Scholar
Discovery of potent pyrrolo-pyrimidine and purine HDAC inhibitors for the treatment of advanced prostate cancer.
D. Moi, D. Bonanni, Silvia Belluti, P. Linciano +6 more
2023European journal of medicinal chemistry21 citations Open access
Semantic Scholar
Investigation of the effect of different linker chemotypes on the inhibition of histone deacetylases (HDACs).
P. Linciano, R. Benedetti, Luca Pinzi, Fabiana Russo +6 more
2020Bioorganic chemistry (Print)19 citations Open access
Semantic Scholar
Multitarget 1,4-Dioxane Compounds Combining Favorable D2-like and 5-HT1A Receptor Interactions with Potential for the Treatment of Parkinson’s Disease or Schizophrenia
F. Del Bello, Dario Ambrosini, A. Bonifazi, A. Newman +8 more
2019ACS Chemical Neuroscience18 citations Open access
Semantic Scholar
Insights into the Structural Conformations of the Tau Protein in Different Aggregation Status
Luca Pinzi, Nicolò Bisi, C. Sorbi, Silvia Franchini +2 more
2023Molecules16 citations Open access
Semantic Scholar
Identification of a Potent and Selective 5-HT1A Receptor Agonist with In Vitro and In Vivo Antinociceptive Activity
P. Linciano, C. Sorbi, A. Comitato, A. Leśniak +16 more
2020ACS Chemical Neuroscience14 citations Open access
Semantic Scholar
Novel Dithiolane-Based Ligands Combining Sigma and NMDA Receptor Interactions as Potential Neuroprotective Agents.
Silvia Franchini, P. Linciano, G. Puja, A. Tait +5 more
2020ACS Medicinal Chemistry Letters13 citations Open access
Semantic Scholar
Structure-affinity/activity relationships of 1,4-dioxa-spiro[4.5]decane based ligands at α1 and 5-HT1A receptors.
Silvia Franchini, U. Battisti, A. Baraldi, A. Prandi +8 more
2014European journal of medicinal chemistry13 citations Open access
Semantic Scholar
(2,2‐Diphenyl‐[1,3]oxathiolan‐5‐ylmethyl)‐(3‐phenyl‐propyl)‐amine: a Potent and Selective 5‐HT1A Receptor Agonist
Silvia Franchini, A. Tait, A. Prandi, C. Sorbi +6 more
2009ChemMedChem12 citations
Semantic Scholar
Helichrysum stoechas (L.) Moench reduces body weight gain and modulates mood disorders via inhibition of silent information regulator 1 (SIRT1) by arzanol
V. Borgonetti, Clarissa Caroli, P. Governa, Brighenti Virginia +7 more
2023Phytotherapy Research11 citations Open access
Semantic Scholar
Synthesis and Antimuscarinic Activity of Derivatives of 2-Substituted-1,3-Dioxolanes
G. Marucci, P. Angeli, L. Brasili, M. Buccioni +5 more
2005Medicinal Chemistry Research11 citations Open access
Semantic Scholar
Structure-Based Discovery of Hsp90/HDAC6 Dual Inhibitors Targeting Aggressive Prostate Cancer
Andrea Citarella, Silvia Belluti, D. Bonanni, Davide Moi +15 more
2025Journal of Medicinal Chemistry10 citations Open access
Semantic Scholar
Exhaustive CoMFA and CoMSIA analyses around different chemical entities: a ligand-based study exploring the affinity and selectivity profiles of 5-HT1A ligands
Sara Guariento, Silvia Franchini, M. Tonelli, P. Fossa +3 more
2017Journal of Enzyme Inhibition and Medicinal Chemistry10 citations Open access
Semantic Scholar
Synthesis and biological evaluation of 1,3-dioxolane-based 5-HT1A receptor agonists for CNS disorders and neuropathic pain.
Silvia Franchini, L. Bencheva, U. Battisti, A. Tait +10 more
2018Future Medicinal Chemistry9 citations
Semantic Scholar
Design and characterization of a mutation outside the active site of human thymidylate synthase that affects ligand binding.
D. Cardinale, O. Salo-Ahen, Giambattista Guaitoli, S. Ferrari +6 more
2010Protein engineering, design & selection : PEDS9 citations Open access
Semantic Scholar
Structure–Activity Relationships within a Series of σ1 and σ2 Receptor Ligands: Identification of a σ2 Receptor Agonist (BS148) with Selective Toxicity against Metastatic Melanoma
Silvia Franchini, C. Sorbi, U. Battisti, A. Tait +12 more
2017ChemMedChem8 citations Open access
Semantic Scholar
Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth
L. Costantino, S. Ferrari, M. Santucci, O. Salo-Ahen +35 more
2022eLife6 citations Open access
Semantic Scholar
Inhibitors of histone deacetylase 6 based on a novel 3-hydroxy-isoxazole zinc binding group
P. Linciano, Luca Pinzi, Silvia Belluti, U. Chianese +7 more
2021Journal of Enzyme Inhibition and Medicinal Chemistry6 citations Open access
Semantic Scholar
Structure-activity relationship at alpha-adrenergic receptors within a series of imidazoline analogues of cirazoline.
M. Pigini, W. Quaglia, Francesco Gentili, G. Marucci +4 more
2000Bioorganic & Medicinal Chemistry6 citations
Semantic Scholar
BS148 Reduces the Aggressiveness of Metastatic Melanoma via Sigma-2 Receptor Targeting
C. Sorbi, Silvia Belluti, C. G. Atene, F. Marocchi +11 more
2023International Journal of Molecular Sciences5 citations Open access
Semantic Scholar
Pharmacological properties and biochemical mechanisms of μ-opioid receptor ligands might be due to different binding poses: MD Studies.
S. Ronsisvalle, Federica Panarello, A. Spadaro, Silvia Franchini +3 more
2020Future Medicinal Chemistry5 citations Open access
Semantic Scholar
Fluorometric detection of protein‐ligand engagement: The case of phosphodiesterase5
G. di Rocco, Ilaria Martinelli, S. Pacifico, R. Guerrini +7 more
2018Journal of Pharmaceutical and Biomedical Analysis5 citations Open access
Semantic Scholar
Synthesis of Heteroaryl ortho-Phenoxyethylamines via Suzuki Cross-Coupling: Easy Access to New Potential Scaffolds in Medicinal Chemistry
Leda Ivanova Manasieva, Battisti Umberto Maria, A. Prandi, L. Brasili +1 more
2015Synthesis5 citations Open access
Semantic Scholar
Correction: Cell-Cycle Inhibition by Helicobacter pylori L-Asparaginase
C. Scotti, P. Sommi, M. Pasquetto, Donata Cappelletti +17 more
2012PLoS ONE5 citations Open access
Semantic Scholar
Diastereoselective Synthesis of (1,3‐Dioxan‐4‐yl)pyrimidine and Purin Nucleoside Analogues
U. Battisti, C. Sorbi, A. Quotadamo, Silvia Franchini +6 more
20154 citations Open access
Semantic Scholar
Transacetalization of Acetals with Butane-1,2,4-triol Using Cobalt(II) Chloride and Chlorotrimethylsilane
U. Battisti, C. Sorbi, Silvia Franchini, A. Tait +1 more
2014Synthesis4 citations Open access
Semantic Scholar
Characterization of factor H-like molecules in rainbow trout
K. I. Zarkadis, G. Sfyroera, Silvia Franchini, A. Sahu +1 more
20004 citations
Semantic Scholar
Synthesis and antimuscarinic activity of some ether- and thioether-bearing 1,3-dioxolanes and related sulfoxides and sulfones.
L. Malmusi, Silvia Franchini, A. Mucci, L. Schenetti +3 more
1998Bioorganic & Medicinal Chemistry4 citations Open access
Semantic Scholar
Molecular modeling and biological studies show that some μ-opioid receptor agonists might elicit analgesia acting as MMP-9 inhibitors.
S. Ronsisvalle, A. Spadaro, Barbara Tomasello, L. Basile +6 more
2019Future Medicinal Chemistry3 citations Open access
Semantic Scholar
Synthesis, structural characterization and biological evaluation of 4′-C-methyl- and phenyl-dioxolane pyrimidine and purine nucleosides
Silvia Franchini, U. Battisti, C. Sorbi, A. Tait +8 more
2017Archives of pharmacal research3 citations Open access
Semantic Scholar
Enantiomeric resolution of [(2,2-diphenyl-1,3-dioxolan-4-yl)methyl](2-phenoxyethyl)amine, a potent α1 and 5-HT1A receptor ligand: an in vitro and computational study
Silvia Franchini, A. Baraldi, C. Sorbi, F. Pellati +5 more
20153 citations Open access
Semantic Scholar
A role of complement component C5 in liver regeneration
D. Mastellos, J. Papadimitriou, Silvia Franchini, P. Tsonis +1 more
20003 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

L. Brasili×28
Invite
L. Brasili — researcher profile on SciRah
C. Sorbi×25
Invite
C. Sorbi — researcher profile on SciRah
A. Tait×14
Invite
A. Tait — researcher profile on SciRah
E. Cichero×13
Invite
E. Cichero — researcher profile on SciRah

×13

Invite

P. Fossa — researcher profile on SciRah

Invite

A. Cilia — researcher profile on SciRah

Invite

G. Marucci — researcher profile on SciRah

Invite

U. Battisti — researcher profile on SciRah

S. Ronsisvalle×9

Invite

S. Ronsisvalle — researcher profile on SciRah

Invite

P. Linciano — researcher profile on SciRah

John D Lambris×8

Invite

John D Lambris — researcher profile on SciRah

Invite

A. Prandi — researcher profile on SciRah