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G. Marucci · SciRah

Researcher profile · Semantic Scholar

G. Marucci

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G. Marucci — researcher profile on SciRah

h-index: 27
Works: 216
Citations: 3,252

Most-cited papers

Efficacy of acetylcholinesterase inhibitors in Alzheimer's disease.
G. Marucci, M. Buccioni, D. Dal Ben, C. Lambertucci +2 more
2020Neuropharmacology957 citations Open access
Semantic Scholar
Frontal Affinity Chromatography—Mass Spectrometry Useful for Characterization of New Ligands for GPR17 Receptor
Enrica Calieri, S. Ceruti, G. Cristalli, C. Martini +14 more
2010Journal of Medicinal Chemistry67 citations Open access
Semantic Scholar
Innovative functional cAMP assay for studying G protein-coupled receptors: application to the pharmacological characterization of GPR17
M. Buccioni, G. Marucci, D. Dal Ben, D. Giacobbe +5 more
2011Purinergic Signalling Purinergic Signalling52 citations Open access
Semantic Scholar
Fragment optimization for GPCRs by molecular dynamics free energy calculations: Probing druggable subpockets of the A2A adenosine receptor binding site
P. Matricon, Anirudh Ranganathan, Eugene P. Warnick, Zhang-Guo Gao +8 more
2017Scientific Reports48 citations Open access
Semantic Scholar
Medicinal chemistry of P2X receptors: agonists and orthosteric antagonists.
C. Lambertucci, D. Dal Ben, M. Buccioni, G. Marucci +2 more
2015Current Medicinal Chemistry47 citations
Semantic Scholar
Evidence for the Existence of a Specific G Protein‐Coupled Receptor Activated by Guanosine
R. Volpini, G. Marucci, M. Buccioni, D. Dal Ben +5 more
2011ChemMedChem45 citations
Semantic Scholar
Adenosine Receptors as Neuroinflammation Modulators: Role of A1 Agonists and A2A Antagonists
Aleix Martí Navia, D. Dal Ben, C. Lambertucci, A. Spinaci +6 more
2020Cells44 citations Open access
Semantic Scholar
Purinergic P2X receptors: structural models and analysis of ligand-target interaction.
D. Dal Ben, M. Buccioni, C. Lambertucci, G. Marucci +2 more
2015European journal of medicinal chemistry42 citations
Semantic Scholar
Update on novel purinergic P2X3 and P2X2/3 receptor antagonists and their potential therapeutic applications
G. Marucci, D. Dal Ben, M. Buccioni, Aleix Martí Navia +3 more
2019Expert Opinion on Therapeutic Patents41 citations Open access
Semantic Scholar
The G Protein‐Coupled Receptor GPR17: Overview and Update
G. Marucci, D. Dal Ben, C. Lambertucci, Claudia Santinelli +4 more
2016ChemMedChem40 citations Open access
Semantic Scholar
Adenosine receptor modeling: what does the A2A crystal structure tell us?
D. Dal Ben, C. Lambertucci, G. Marucci, R. Volpini +1 more
2010Current Topics in Medicinal Chemistry39 citations
Semantic Scholar
Synthesis and biological evaluation of 2-alkynyl-N6-methyl-5'-N-methylcarboxamidoadenosine derivatives as potent and highly selective agonists for the human adenosine A3 receptor.
R. Volpini, M. Buccioni, D. Dal Ben, C. Lambertucci +5 more
2009Journal of Medicinal Chemistry37 citations Open access
Semantic Scholar
Neuroprotective potential of adenosine A1 receptor partial agonists in experimental models of cerebral ischemia
A. Martire, C. Lambertucci, R. Pepponi, A. Ferrante +7 more
2019Journal of Neurochemistry36 citations Open access
Semantic Scholar
Choline-Containing Phospholipids: Structure-Activity Relationships Versus Therapeutic Applications.
S. Tayebati, G. Marucci, Claudia Santinelli, M. Buccioni +1 more
2015Current Medicinal Chemistry36 citations
Semantic Scholar
Synthesis, biological evaluation, and docking studies of tetrahydrofuran- cyclopentanone- and cyclopentanol-based ligands acting at adrenergic α₁- and serotonine 5-HT1A receptors.
A. Prandi, Silvia Franchini, Leda Ivanova Manasieva, P. Fossa +6 more
2012Journal of Medicinal Chemistry36 citations Open access
Semantic Scholar
The 1,2,4-Triazolo[4,3-a]pyrazin-3-one as a Versatile Scaffold for the Design of Potent Adenosine Human Receptor Antagonists. Structural Investigations to Target the A2A Receptor Subtype.
M. Falsini, L. Squarcialupi, D. Catarzi, F. Varano +8 more
2017Journal of Medicinal Chemistry31 citations Open access
Semantic Scholar
1,3‐Dioxolane‐Based Ligands as Rigid Analogues of Naftopidil: Structure–Affinity/Activity Relationships at α1 and 5‐HT1A Receptors
C. Sorbi, Silvia Franchini, A. Tait, A. Prandi +6 more
2009ChemMedChem30 citations Open access
Semantic Scholar
Adenosine A2A Receptor Antagonists: New 8‐Substituted 9‐Ethyladenines as Tools for in vivo Rat Models of Parkinson's Disease
R. Volpini, D. Dal Ben, C. Lambertucci, G. Marucci +6 more
2009ChemMedChem27 citations
Semantic Scholar
Blockage of A2A and A3 adenosine receptors decreases the desensitization of human GABAA receptors microtransplanted to Xenopus oocytes
Cristina Roseti, E. Palma, K. Martinello, S. Fucile +16 more
2009Proceedings of the National Academy of Sciences of the United States of America26 citations Open access
Semantic Scholar
P2X3 Receptor Ligands: Structural Features and Potential Therapeutic Applications
A. Spinaci, M. Buccioni, D. Dal Ben, G. Marucci +2 more
2021Frontiers in Pharmacology24 citations Open access
Semantic Scholar
Antiproliferative Evaluation of Isofuranodiene on Breast and Prostate Cancer Cell Lines
M. Buccioni, D. Dal Ben, C. Lambertucci, F. Maggi +4 more
2014TheScientificWorldJournal24 citations Open access
Semantic Scholar
1,3-Dioxolane-based ligands incorporating a lactam or imide moiety: structure-affinity/activity relationship at alpha1-adrenoceptor subtypes and at 5-HT1A receptors.
Silvia Franchini, A. Prandi, A. Baraldi, C. Sorbi +8 more
2010European journal of medicinal chemistry24 citations Open access
Semantic Scholar
Molecular modeling study on potent and selective adenosine A(3) receptor agonists.
D. Dal Ben, M. Buccioni, C. Lambertucci, G. Marucci +3 more
2010Bioorganic & Medicinal Chemistry24 citations Open access
Semantic Scholar
Acetylshikonin isolated from Lithospermum erythrorhizon roots inhibits dihydrofolate reductase and hampers autochthonous mammary carcinogenesis in Δ16HER2 transgenic mice.
Jun-Biao Wang, R. Iannarelli, S. Pucciarelli, E. Laudadio +14 more
2020Pharmacological Research22 citations Open access
Semantic Scholar
Adenine-based acyclic nucleotides as novel P2X3 receptor ligands.
R. Volpini, R. Mishra, Dhuldeo D. Kachare, D. Dal Ben +7 more
2009Journal of Medicinal Chemistry20 citations
Semantic Scholar
A2A Adenosine Receptor Antagonists and their Potential in Neurological Disorders.
C. Lambertucci, G. Marucci, D. Catarzi, V. Colotta +4 more
2022Current Medicinal Chemistry19 citations
Semantic Scholar
The Anti-Inflammatory and Pain-Relieving Effects of AR170, an Adenosine A3 Receptor Agonist, in a Rat Model of Colitis
L. Antonioli, E. Lucarini, C. Lambertucci, M. Fornai +9 more
2020Cells19 citations Open access
Semantic Scholar
Antioxidant-conjugated 1,2,4-Triazolo[4,3-a]pyrazin-3-one Derivatives: Highly Potent and Selective Human A2A Adenosine Receptor Antagonists Possessing Protective Efficacy in Neuropathic Pain.
M. Falsini, D. Catarzi, F. Varano, Costanza Ceni +10 more
2019Journal of Medicinal Chemistry19 citations Open access
Semantic Scholar
Comparison and optimization of transient transfection methods at human astrocytoma cell line 1321N1.
G. Marucci, C. Lammi, M. Buccioni, D. Dal Ben +8 more
2011Analytical Biochemistry19 citations
Semantic Scholar
The possible role of the nucleoside adenosine in countering skin aging: A review
G. Marucci, M. Buccioni, V. Varlaro, R. Volpini +1 more
2022Biofactors18 citations Open access
Semantic Scholar
Butter oil (ghee) enrichment with aromatic plants: Chemical characterization and effects on fibroblast migration in anin-vitro wound healing model
Afraa Maiza, Franks Kamgang Nzekoue, Tesmine Ghazouani, M. Afif +8 more
202018 citations Open access
Semantic Scholar
GPR17 receptor modulators and their therapeutic implications: review of recent patents
G. Marucci, D. Dal Ben, C. Lambertucci, Aleix Martí Navia +3 more
2019Expert Opinion on Therapeutic Patents18 citations Open access
Semantic Scholar
Anticancer activity study of A3 adenosine receptor agonists☆
G. Marucci, Claudia Santinelli, M. Buccioni, Aleix Martí Navia +5 more
2018Life Science18 citations Open access
Semantic Scholar
Different efficacy of adenosine and NECA derivatives at the human A3 adenosine receptor: insight into the receptor activation switch.
D. Dal Ben, M. Buccioni, C. Lambertucci, Sonja Kachler +6 more
2014Biochemical Pharmacology18 citations
Semantic Scholar
Development of new chromatographic tools based on A2A adenosine receptor subtype for ligand characterization and screening by FAC-MS
C. Temporini, G. Massolini, G. Marucci, C. Lambertucci +3 more
2012Analytical and Bioanalytical Chemistry18 citations
Semantic Scholar
New potent and selective A1 adenosine receptor antagonists as potential tools for the treatment of gastrointestinal diseases.
C. Lambertucci, G. Marucci, D. Dal Ben, M. Buccioni +4 more
2018European journal of medicinal chemistry17 citations Open access
Semantic Scholar
“Dual Anta-Inhibitors” of the A2A Adenosine Receptor and Casein Kinase CK1delta: Synthesis, Biological Evaluation, and Molecular Modeling Studies
A. Spinaci, M. Buccioni, D. Catarzi, Chang Cui +14 more
2023Pharmaceuticals14 citations Open access
Semantic Scholar
Novel 8-amino-1,2,4-triazolo[4,3-a]pyrazin-3-one derivatives as potent human adenosine A1 and A2A receptor antagonists. Evaluation of their protective effect against β-amyloid-induced neurotoxicity in SH-SY5Y cells.
M. Falsini, D. Catarzi, F. Varano, D. Dal Ben +6 more
2019Bioorganic chemistry (Print)14 citations Open access
Semantic Scholar
Neuropeptide S Receptor: Recent Updates on Nonpeptide Antagonist Discovery
D. Dal Ben, I. Antonini, M. Buccioni, C. Lambertucci +4 more
2011ChemMedChem14 citations
Semantic Scholar
Molecular Modeling Studies on the Human Neuropeptide S Receptor and Its Antagonists
D. Dal Ben, I. Antonini, M. Buccioni, C. Lambertucci +4 more
2010ChemMedChem14 citations
Semantic Scholar
Non-Nucleoside Agonists of the Adenosine Receptors: An Overview
D. Dal Ben, C. Lambertucci, M. Buccioni, Aleix Martí Navia +3 more
2019Pharmaceuticals13 citations Open access
Semantic Scholar
Ex‐vivo absorption study of lysine R‐lipoate salt, a new pharmaceutical form of R‐ALA
F. Amenta, M. Buccioni, D. Dal Ben, C. Lambertucci +6 more
2018European Journal of Pharmaceutical Sciences13 citations Open access
Semantic Scholar
The Length and Flexibility of the 2‐Substituent of 9‐Ethyladenine Derivatives Modulate Affinity and Selectivity for the Human A2A Adenosine Receptor
Ajiroghene Thomas, M. Buccioni, D. Dal Ben, C. Lambertucci +6 more
2016ChemMedChem13 citations Open access
Semantic Scholar
Structure-affinity/activity relationships of 1,4-dioxa-spiro[4.5]decane based ligands at α1 and 5-HT1A receptors.
Silvia Franchini, U. Battisti, A. Baraldi, A. Prandi +8 more
2014European journal of medicinal chemistry13 citations Open access
Semantic Scholar
Novel human adenosine receptor antagonists based on the 7-amino-thiazolo[5,4-d]pyrimidine scaffold. Structural investigations at the 2-, 5- and 7-positions to enhance affinity and tune selectivity.
F. Varano, D. Catarzi, M. Falsini, D. Dal Ben +4 more
2019Bioorganic & Medicinal Chemistry Letters12 citations Open access
Semantic Scholar
Investigation on 2',3'-O-Substituted ATP Derivatives and Analogs as Novel P2X3 Receptor Antagonists.
D. Dal Ben, M. Buccioni, C. Lambertucci, G. Marucci +6 more
2018ACS Medicinal Chemistry Letters12 citations Open access
Semantic Scholar
High affinity ligands and potent antagonists for the α1D-adrenergic receptor. Novel 3,8-disubstituted [1]benzothieno[3,2-d]pyrimidine derivatives.
G. Romeo, L. Salerno, V. Pittalà, M. Modica +5 more
2014European journal of medicinal chemistry12 citations Open access
Semantic Scholar
Combined Therapy of A1AR Agonists and A2AAR Antagonists in Neuroinflammation
G. Marucci, D. Dal Ben, C. Lambertucci, Aleix Martí Navia +3 more
2021Molecules11 citations Open access
Semantic Scholar
2′,3′-O-Substituted ATP derivatives as potent antagonists of purinergic P2X3 receptors and potential analgesic agents
D. Dal Ben, A. Marchenkova, Ajiroghene Thomas, C. Lambertucci +4 more
2017Purinergic Signalling Purinergic Signalling10 citations Open access
Semantic Scholar
Identification of alpha1-adrenoceptor subtypes involved in contraction of young CD rat epididymal vas deferens.
M. Buccioni, M. Kandhavelu, P. Angeli, G. Cristalli +6 more
2009European Journal of Pharmacology10 citations
Semantic Scholar

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R. Volpini×40
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R. Volpini — researcher profile on SciRah
M. Buccioni×39
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M. Buccioni — researcher profile on SciRah
C. Lambertucci×37
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C. Lambertucci — researcher profile on SciRah
D. Dal Ben×36
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D. Dal Ben — researcher profile on SciRah

×15

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A. Spinaci — researcher profile on SciRah

G. Cristalli×14

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G. Cristalli — researcher profile on SciRah

Ajiroghene Thomas×11

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Ajiroghene Thomas — researcher profile on SciRah

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K. Klotz — researcher profile on SciRah

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D. Catarzi — researcher profile on SciRah

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F. Varano — researcher profile on SciRah

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V. Colotta — researcher profile on SciRah

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Aleix Martí Navia — researcher profile on SciRah