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M. Tonelli · SciRah

Researcher profile · Semantic Scholar

M. Tonelli

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M. Tonelli — researcher profile on SciRah

h-index: 26
Works: 76
Citations: 1,800

Most-cited papers

Antiviral activity of benzimidazole derivatives. II. Antiviral activity of 2-phenylbenzimidazole derivatives.
M. Tonelli, M. Simone, B. Tasso, F. Novelli +10 more
2010Bioorganic & Medicinal Chemistry185 citations
Semantic Scholar
Antiviral and cytotoxic activities of aminoarylazo compounds and aryltriazene derivatives
M. Tonelli, I. Vazzana, B. Tasso, V. Boido +10 more
2009Bioorganic & Medicinal Chemistry89 citations Open access
Semantic Scholar
Antiviral Activity of Benzimidazole Derivatives. I. Antiviral Activity of 1‐Substituted‐2‐[(Benzotriazol‐1/2‐yl)methyl]benzimidazoles
M. Tonelli, G. Paglietti, V. Boido, F. Sparatore +4 more
2008Chemistry and Biodiversity84 citations
Semantic Scholar
Antiviral activity of benzimidazole derivatives. III. Novel anti-CVB-5, anti-RSV and anti-Sb-1 agents.
M. Tonelli, F. Novelli, B. Tasso, I. Vazzana +10 more
2014Bioorganic & Medicinal Chemistry78 citations
Semantic Scholar
Acridine derivatives as anti-BVDV agents.
M. Tonelli, G. Vettoretti, B. Tasso, F. Novelli +8 more
2011Antiviral Research68 citations
Semantic Scholar
Synthesis and Biological Evaluation of Novel (thio)semicarbazone-Based Benzimidazoles as Antiviral Agents against Human Respiratory Viruses
Valeria Francesconi, E. Cichero, S. Schenone, L. Naesens +1 more
2020Molecules63 citations Open access
Semantic Scholar
Quinolizidinyl derivatives of bi- and tricyclic systems as potent inhibitors of acetyl- and butyrylcholinesterase with potential in Alzheimer's disease.
B. Tasso, M. Catto, O. Nicolotti, F. Novelli +7 more
2011European journal of medicinal chemistry63 citations Open access
Semantic Scholar
Journey on Naphthoquinone and Anthraquinone Derivatives: New Insights in Alzheimer’s Disease
Marta Campora, Valeria Francesconi, S. Schenone, B. Tasso +1 more
2021Pharmaceuticals59 citations Open access
Semantic Scholar
Benzimidazole derivatives endowed with potent antileishmanial activity
M. Tonelli, E. Gabriele, F. Piazza, N. Basilico +5 more
2017Journal of Enzyme Inhibition and Medicinal Chemistry48 citations Open access
Semantic Scholar
Multitarget Therapeutic Leads for Alzheimer’s Disease: Quinolizidinyl Derivatives of Bi‐ and Tricyclic Systems as Dual Inhibitors of Cholinesterases and β‐Amyloid (Aβ) Aggregation
M. Tonelli, M. Catto, B. Tasso, F. Novelli +9 more
2015ChemMedChem46 citations Open access
Semantic Scholar
Magnolol and Luteolin Inhibition of α-Glucosidase Activity: Kinetics and Type of Interaction Detected by In Vitro and In Silico Studies
F. Djeujo, E. Ragazzi, Miriana Urettini, Beatrice Sauro +3 more
2022Pharmaceuticals42 citations Open access
Semantic Scholar
Inhibition of Chloride Intracellular Channel 1 (CLIC1) as Biguanide Class-Effect to Impair Human Glioblastoma Stem Cell Viability
F. Barbieri, Roberto Würth, A. Pattarozzi, I. Verduci +9 more
2018Frontiers in Pharmacology42 citations Open access
Semantic Scholar
Pharmacophore modeling, resistant mutant isolation, docking, and MM-PBSA analysis: Combined experimental/computer-assisted approaches to identify new inhibitors of the bovine viral diarrhea virus (BVDV).
M. Tonelli, V. Boido, P. la Colla, R. Loddo +4 more
2010Bioorganic & Medicinal Chemistry41 citations
Semantic Scholar
Novel biguanide-based derivatives scouted as TAAR1 agonists: Synthesis, biological evaluation, ADME prediction and molecular docking studies.
M. Tonelli, S. Espinoza, R. Gainetdinov, E. Cichero
2017European journal of medicinal chemistry39 citations Open access
Semantic Scholar
Chloride intracellular channel 1 activity is not required for glioblastoma development but its inhibition dictates glioma stem cell responsivity to novel biguanide derivatives
F. Barbieri, A. Bosio, A. Pattarozzi, M. Tonelli +17 more
2022Journal of experimental & clinical cancer research : CR37 citations Open access
Semantic Scholar
Multitarget Biological Profiling of New Naphthoquinone and Anthraquinone-Based Derivatives for the Treatment of Alzheimer’s Disease
Marta Campora, C. Canale, Elena Gatta, B. Tasso +5 more
2021ACS Chemical Neuroscience37 citations Open access
Semantic Scholar
Synergistic experimental/computational studies on arylazoenamine derivatives that target the bovine viral diarrhea virus RNA-dependent RNA polymerase.
G. Giliberti, Cristina Ibba, Esther Marongiu, R. Loddo +6 more
2010Bioorganic & Medicinal Chemistry35 citations
Semantic Scholar
Host dihydrofolate reductase (DHFR)-directed cycloguanil analogues endowed with activity against influenza virus and respiratory syncytial virus
M. Tonelli, L. Naesens, Sabrina Gazzarrini, M. Santucci +5 more
2017European journal of medicinal chemistry32 citations Open access
Semantic Scholar
Rational design, chemical synthesis and biological evaluation of novel biguanides exploring species-specificity responsiveness of TAAR1 agonists.
Sara Guariento, M. Tonelli, S. Espinoza, A. Gerasimov +2 more
2018European journal of medicinal chemistry30 citations Open access
Semantic Scholar
Anti-α-Glucosidase and Antiglycation Activities of α-Mangostin and New Xanthenone Derivatives: Enzymatic Kinetics and Mechanistic Insights through In Vitro Studies
F. Djeujo, Valeria Francesconi, Maddalena Gonella, E. Ragazzi +2 more
2022Molecules29 citations Open access
Semantic Scholar
Probing In Silico the Benzimidazole Privileged Scaffold for the Development of Drug-like Anti-RSV Agents
E. Cichero, Alessio Calautti, Valeria Francesconi, M. Tonelli +2 more
2021Pharmaceuticals29 citations Open access
Semantic Scholar
A homology modelling-driven study leading to the discovery of the first mouse trace amine-associated receptor 5 (TAAR5) antagonists
E. Cichero, S. Espinoza, M. Tonelli, Silvia Franchini +5 more
201629 citations Open access
Semantic Scholar
Efficacy of Novel Acridine Derivatives in the Inhibition of hPrP90-231 Prion Protein Fragment Toxicity
V. Villa, M. Tonelli, S. Thellung, A. Corsaro +12 more
2011Neurotoxicity research29 citations
Semantic Scholar
Antitarget, Anti-SARS-CoV-2 Leads, Drugs, and the Drug Discovery–Genetics Alliance Perspective
C. Pozzi, A. Vanet, Valeria Francesconi, Lorenzo Tagliazucchi +6 more
2023Journal of Medicinal Chemistry28 citations Open access
Semantic Scholar
Novel celecoxib analogues inhibit glial production of prostaglandin E2, nitric oxide, and oxygen radicals reverting the neuroinflammatory responses induced by misfolded prion protein fragment 90-231 or lipopolysaccharide.
V. Villa, S. Thellung, A. Bajetto, E. Gatta +5 more
2016Pharmacological Research26 citations
Semantic Scholar
Clofazimine analogs with antileishmanial and antiplasmodial activity.
A. Barteselli, Manolo Casagrande, N. Basilico, S. Parapini +6 more
2015Bioorganic & Medicinal Chemistry26 citations
Semantic Scholar
Antimicrobial and cytotoxic arylazoenamines. Part III: antiviral activity of selected classes of arylazoenamines.
M. Tonelli, V. Boido, C. Canu, A. Sparatore +9 more
2008Bioorganic & Medicinal Chemistry26 citations
Semantic Scholar
State-of-the-art Review on the Antiparasitic Activity of Benzimidazole-based Derivatives: Facing Malaria, Leishmaniasis, and Trypanosomiasis
Valeria Francesconi, Marco Rizzo, Silvia Schenone, Anna Carbone +1 more
2023Current Medicinal Chemistry24 citations Open access
Semantic Scholar
Pyrazole and imidazo[1,2-b]pyrazole Derivatives as New Potential Antituberculosis Agents.
Elda Meta, C. Brullo, M. Tonelli, S. Franzblau +6 more
2019Medicinal chemistry24 citations
Semantic Scholar
Synthesis, biological evaluation and molecular modeling of novel azaspiro dihydrotriazines as influenza virus inhibitors targeting the host factor dihydrofolate reductase (DHFR)
Valeria Francesconi, L. Giovannini, M. Santucci, E. Cichero +4 more
2018European Journal of Medicinal Chemistry23 citations Open access
Semantic Scholar
Fight Against H1N1 Influenza A Virus: Recent Insights Towards the Development of Druggable Compounds.
M. Tonelli, E. Cichero
2016Current Medicinal Chemistry23 citations
Semantic Scholar
Thioxanthenone-based derivatives as multitarget therapeutic leads for Alzheimer's disease.
M. Tonelli, M. Catto, R. Sabaté, Valeria Francesconi +11 more
2023European journal of medicinal chemistry22 citations Open access
Semantic Scholar
Novel 1-Amidino-4-Phenylpiperazines as Potent Agonists at Human TAAR1 Receptor: Rational Design, Synthesis, Biological Evaluation and Molecular Docking Studies
Valeria Francesconi, E. Cichero, Evgeny V. Kanov, E. Laurini +3 more
2020Pharmaceuticals22 citations Open access
Semantic Scholar
Antiviral activity of benzotriazole derivatives. 5-[4-(Benzotriazol-2-yl)phenoxy]-2,2-dimethylpentanoic acids potently and selectively inhibit Coxsackie Virus B5.
R. Loddo, F. Novelli, A. Sparatore, B. Tasso +7 more
2015Bioorganic & Medicinal Chemistry21 citations Open access
Semantic Scholar
Celecoxib Inhibits Prion Protein 90-231-Mediated Pro-inflammatory Responses in Microglial Cells
V. Villa, S. Thellung, A. Corsaro, F. Novelli +5 more
2014Molecular Neurobiology21 citations
Semantic Scholar
Evidence of Pyrimethamine and Cycloguanil Analogues as Dual Inhibitors of Trypanosoma brucei Pteridine Reductase and Dihydrofolate Reductase
G. Tassone, G. Landi, P. Linciano, Valeria Francesconi +5 more
2021Pharmaceuticals18 citations Open access
Semantic Scholar
Synthesis and Antiplasmodial Activity of Novel Chloroquine Analogues with Bulky Basic Side Chains
B. Tasso, F. Novelli, M. Tonelli, A. Barteselli +5 more
2015ChemMedChem18 citations
Semantic Scholar
Optimization of the clofazimine structure leads to a highly water-soluble C3-aminopyridinyl riminophenazine endowed with improved anti-Wnt and anti-cancer activity in vitro and in vivo.
A. Koval, I. Bassanini, Jia-Bing Xu, M. Tonelli +7 more
2021European journal of medicinal chemistry16 citations Open access
Semantic Scholar
Trace amine associated receptor 1 (TAAR1) modulators: a patent review (2010-present)
M. Tonelli, E. Cichero
2019Expert Opinion on Therapeutic Patents16 citations
Semantic Scholar
New insights into the structure of the trace amine‐associated receptor 2: Homology modelling studies exploring the binding mode of 3‐iodothyronamine
E. Cichero, M. Tonelli
2017Chemical Biology and Drug Design16 citations
Semantic Scholar
Targeting species-specific trace amine-associated receptor 1 ligands: to date perspective of the rational drug design process.
E. Cichero, M. Tonelli
2017Future Medicinal Chemistry16 citations
Semantic Scholar
Novel Thiazole-Based SIRT2 Inhibitors Discovered via Molecular Modelling Studies and Enzymatic Assays
Elena Abbotto, Beatrice Casini, Francesco Piacente, Naomi Scarano +7 more
2023Pharmaceuticals15 citations Open access
Semantic Scholar
Novel quinolizidinyl derivatives as antiarrhythmic agents: 2. Further investigation.
B. Tasso, R. Budriesi, I. Vazzana, Pierfranco Ioan +6 more
2010Journal of Medicinal Chemistry15 citations Open access
Semantic Scholar
Deciphering the landscape of allosteric glutaminase 1 inhibitors as anticancer agents.
C. Vagaggini, Pasqualina D’Ursi, F. Poggialini, Paola Fossa +7 more
2025Bioorganic chemistry (Print)13 citations Open access
Semantic Scholar
9-Aminoacridine-based agents impair the bovine viral diarrhea virus (BVDV) replication targeting the RNA-dependent RNA polymerase (RdRp).
R. Loddo, Valeria Francesconi, E. Laurini, Silvia Boccardo +4 more
2018Bioorganic & Medicinal Chemistry13 citations Open access
Semantic Scholar
High-Throughput Phenotypic Screening and Machine Learning Methods Enabled the Selection of Broad-Spectrum Low-Toxicity Antitrypanosomatidic Agents
P. Linciano, A. Quotadamo, R. Luciani, M. Santucci +18 more
2023Journal of Medicinal Chemistry12 citations Open access
Semantic Scholar
Benzimidazole-based derivatives as privileged scaffold developed for the treatment of the RSV infection: a computational study exploring the potency and cytotoxicity profiles
E. Cichero, M. Tonelli, F. Novelli, B. Tasso +4 more
2017Journal of Enzyme Inhibition and Medicinal Chemistry11 citations Open access
Semantic Scholar
Exhaustive CoMFA and CoMSIA analyses around different chemical entities: a ligand-based study exploring the affinity and selectivity profiles of 5-HT1A ligands
Sara Guariento, Silvia Franchini, M. Tonelli, P. Fossa +3 more
2017Journal of Enzyme Inhibition and Medicinal Chemistry10 citations Open access
Semantic Scholar
Molecular Docking and QSAR Studies as Computational Tools Exploring the Rescue Ability of F508del CFTR Correctors
Giada Righetti, M. Casale, N. Liessi, B. Tasso +6 more
2020International Journal of Molecular Sciences9 citations Open access
Semantic Scholar
Exploring the effectiveness of novel benzimidazoles as CB2 ligands: synthesis, biological evaluation, molecular docking studies and ADMET prediction.
M. Tonelli, E. Cichero, Ali Mokhtar Mahmoud, Alessandro Rabbito +3 more
2018MedChemComm9 citations Open access
Semantic Scholar

Frequent co-authors

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B. Tasso×19
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B. Tasso — researcher profile on SciRah
E. Cichero×18
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E. Cichero — researcher profile on SciRah
F. Sparatore×16
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F. Sparatore — researcher profile on SciRah
V. Boido×14
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V. Boido — researcher profile on SciRah

Valeria Francesconi

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Valeria Francesconi — researcher profile on SciRah

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F. Novelli — researcher profile on SciRah

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R. Loddo — researcher profile on SciRah

A. Sparatore×11

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A. Sparatore — researcher profile on SciRah

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S. Pricl — researcher profile on SciRah

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P. la Colla — researcher profile on SciRah

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P. Fossa — researcher profile on SciRah

G. Giliberti×5

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G. Giliberti — researcher profile on SciRah