Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

D. Mastellos · SciRah

Researcher profile · Semantic Scholar

D. Mastellos

Share profile

D. Mastellos — researcher profile on SciRah

h-index: 44
Works: 105
Citations: 9,307

Most-cited papers

Complement and tissue factor-enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis
P. Skendros, Alexandros Mitsios, A. Chrysanthopoulou, D. Mastellos +13 more
2020medRxiv706 citations Open access
Semantic Scholar
A Novel C5a Receptor-Tissue Factor Cross-Talk in Neutrophils Links Innate Immunity to Coagulation Pathways1
K. Ritis, M. Doumas, D. Mastellos, A. Micheli +6 more
2006Journal of Immunology504 citations Open access
Semantic Scholar
Complement as a target in COVID-19?
A. Risitano, D. Mastellos, M. Huber-Lang, Despina Yancopoulou +3 more
2020Nature reviews. Immunology461 citations Open access
Semantic Scholar
The Proinflammatory Mediators C3a and C5a Are Essential for Liver Regeneration
C. Strey, M. Markiewski, D. Mastellos, Ruxandra Tudoran +3 more
2003Journal of Experimental Medicine460 citations Open access
Semantic Scholar
Novel Mechanisms and Functions of Complement
G. Hajishengallis, E. Reis, D. Mastellos, D. Ricklin +1 more
2017Nature Immunology440 citations Open access
Semantic Scholar
Complement component C3 - The “Swiss Army Knife” of innate immunity and host defense
D. Ricklin, E. Reis, D. Mastellos, P. Gros +1 more
2016Immunological Reviews427 citations Open access
Semantic Scholar
Complement in cancer: untangling an intricate relationship
E. Reis, D. Mastellos, D. Ricklin, A. Mantovani +1 more
2017Nature reviews. Immunology394 citations Open access
Semantic Scholar
New Insights into the Immune Functions of Complement
E. Reis, D. Mastellos, G. Hajishengallis, John D Lambris
2019Nature reviews. Immunology388 citations Open access
Semantic Scholar
The renaissance of complement therapeutics
D. Ricklin, D. Mastellos, E. Reis, John D Lambris
2017Nature Reviews Nephrology346 citations Open access
Semantic Scholar
Clinical promise of next-generation complement therapeutics
D. Mastellos, D. Ricklin, John D Lambris
2019Nature reviews. Drug discovery297 citations Open access
Semantic Scholar
A guide to complement biology, pathology and therapeutic opportunity
D. Mastellos, G. Hajishengallis, John D Lambris
2023Nature reviews. Immunology293 citations
Semantic Scholar
The first case of COVID-19 treated with the complement C3 inhibitor AMY-101
S. Mastaglio, Annalisa Ruggeri, A. Risitano, P. Angelillo +8 more
2020Clinical Immunology280 citations Open access
Semantic Scholar
Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1.
R. Reca, D. Mastellos, M. Majka, L. Marquez +8 more
2003Blood241 citations Open access
Semantic Scholar
Increased C5a receptor expression in sepsis.
N. Riedemann, R. Guo, T. Neff, I. J. Laudes +9 more
2002Journal of Clinical Investigation225 citations Open access
Semantic Scholar
Complement
D. Mastellos, D. Morikis, Stuart N. Isaacs, M. C. Holland +2 more
2003Immunologic research222 citations Open access
Semantic Scholar
Complement C3 vs C5 inhibition in severe COVID-19: Early clinical findings reveal differential biological efficacy
D. Mastellos, Bruno G. P. Pires da Silva, Benedito Antonio Lopes da Fonseca, N. P. Fonseca +19 more
2020medRxiv210 citations Open access
Semantic Scholar
Compstatin: a C3-targeted complement inhibitor reaching its prime for bedside intervention
D. Mastellos, Despina Yancopoulou, P. Kokkinos, M. Huber-Lang +7 more
2015European Journal of Clinical Investigation203 citations Open access
Semantic Scholar
Protection of innate immunity by C5aR antagonist in septic mice
M. Huber-Lang, Niels C. Riedeman, J. Sarma, E. Younkin +11 more
2002The FASEB Journal186 citations Open access
Semantic Scholar
C3a and C3b Activation Products of the Third Component of Complement (C3) Are Critical for Normal Liver Recovery after Toxic Injury1
M. Markiewski, D. Mastellos, Ruxandra Tudoran, R. Deangelis +5 more
2004Journal of Immunology178 citations Open access
Semantic Scholar
Complement: more than a 'guard' against invading pathogens?
D. Mastellos, John D Lambris
2002Trends in immunology173 citations
Semantic Scholar
Complement Component 3 Is Required for Optimal Expansion of CD8 T Cells During a Systemic Viral Infection1
M. Suresh, H. Molina, M. Salvato, D. Mastellos +2 more
2003Journal of Immunology136 citations Open access
Semantic Scholar
Complement C5a Receptor Is Essential for the Optimal Generation of Antiviral CD8+ T Cell Responses1
A. Kim, I. Dimitriou, M. C. Holland, D. Mastellos +4 more
2004Journal of Immunology119 citations
Semantic Scholar
Herpes Simplex Virus Type 1 Evades the Effects of Antibody and Complement In Vivo
J. Lubinski, Ming Jiang, L. Hook, Yueh J. Chang +6 more
2002Journal of Virology107 citations Open access
Semantic Scholar
Complement in Thrombotic Microangiopathies: Unraveling Ariadne's Thread Into the Labyrinth of Complement Therapeutics
E. Gavriilaki, A. Anagnostopoulos, D. Mastellos
2019Frontiers in Immunology97 citations Open access
Semantic Scholar
Complement-triggered pathways orchestrate regenerative responses throughout phylogenesis
D. Mastellos, R. Deangelis, John D Lambris
2013Seminars in Immunology87 citations Open access
Semantic Scholar
Complement-Dependent Mechanisms and Interventions in Periodontal Disease
G. Hajishengallis, T. Kajikawa, E. Hajishengallis, T. Maekawa +5 more
2019Frontiers in Immunology84 citations Open access
Semantic Scholar
Targeting complement components C3 and C5 for the retina: Key concepts and lingering questions
Benjamin J. Kim, D. Mastellos, Ya-Feng Li, J. Dunaief +1 more
2020Progress in retinal and eye research79 citations Open access
Semantic Scholar
Novel monoclonal antibodies against mouse C3 interfering with complement activation: description of fine specificity and applications to various immunoassays.
D. Mastellos, J. Prechl, G. László, K. Papp +7 more
2004Molecular Immunology71 citations
Semantic Scholar
C5a causes limited, polymorphonuclear cell-independent, mesenteric ischemia/reperfusion-induced injury.
S. Fleming, D. Mastellos, G. Karpel-Massler, T. Shea‐donohue +2 more
2003Clinical Immunology71 citations
Semantic Scholar
Applying Complement Therapeutics to Rare Diseases
E. Reis, D. Mastellos, Despina Yancopoulou, A. Risitano +2 more
2015Clinical Immunology66 citations Open access
Semantic Scholar
Phase 2a clinical trial of complement C3 inhibitor AMY-101 in adults with periodontal inflammation.
H. Hasturk, G. Hajishengallis, John D Lambris, D. Mastellos +1 more
2021Journal of Clinical Investigation62 citations Open access
Semantic Scholar
Compstatins: The dawn of clinical C3-targeted complement inhibition
Christina Lamers, D. Mastellos, D. Ricklin, John D Lambris
2022TIPS - Trends in Pharmacological Sciences60 citations Open access
Semantic Scholar
Complement-mediated clearance of erythrocytes: mechanism and delineation of the regulatory roles of Crry and DAF. Decay-accelerating factor.
H. Molina, T. Miwa, Lin Zhou, Brendan Hilliard +4 more
2002Blood58 citations
Semantic Scholar
Therapeutic targeting of the complement system
D. Ricklin, D. Mastellos, John D Lambris
2019Nature reviews. Drug discovery52 citations Open access
Semantic Scholar
Complement C3 inhibition in severe COVID-19 using compstatin AMY-101
P. Skendros, Georgios S. Germanidis, D. Mastellos, C. Antoniadou +31 more
2022Science Advances51 citations Open access
Semantic Scholar
Complement in paroxysmal nocturnal hemoglobinuria: exploiting our current knowledge to improve the treatment landscape
D. Mastellos, D. Ricklin, Despina Yancopoulou, A. Risitano +1 more
2014Expert Review of Hematology49 citations Open access
Semantic Scholar
A modular integrated lab-on-a-chip platform for fast and highly efficient sample preparation for foodborne pathogen screening
K. Tsougeni, Athina S. Kastania, Georgia Kaprou, Michael J. Eck +6 more
2019Sensors and actuators. B, Chemical48 citations
Semantic Scholar
C3-targeted therapy in periodontal disease: moving closer to the clinic
G. Hajishengallis, H. Hasturk, John D Lambris, D. Apatzidou +29 more
2021Trends in immunology47 citations Open access
Semantic Scholar
Novel biological networks modulated by complement.
D. Mastellos, C. Andronis, Andreas Persidis, John D Lambris
2005Clinical Immunology46 citations
Semantic Scholar
Safety Profile After Prolonged C3 Inhibition
E. Reis, Nadja Berger, Xin Wang, S. Koutsogiannaki +17 more
2018Clinical Immunology45 citations Open access
Semantic Scholar
Complement C3-Targeted Therapy: Replacing Long-Held Assertions with Evidence-Based Discovery
D. Mastellos, E. Reis, D. Ricklin, Richard J. H. Smith +1 more
2017Trends in immunology43 citations Open access
Semantic Scholar
Bactericidal Action of Smooth and Plasma Micro‐Nanotextured Polymeric Surfaces with Varying Wettability, Enhanced by Incorporation of a Biocidal Agent
P. Dimitrakellis, K. Ellinas, G. Kaprou, D. Mastellos +2 more
202140 citations
Semantic Scholar
Complement therapeutics in inflammatory diseases: promising drug candidates for C3-targeted intervention
D. Mastellos, D. Ricklin, E. Hajishengallis, G. Hajishengallis +1 more
2015Molecular Oral Microbiology40 citations Open access
Semantic Scholar
Complement emerges as a masterful regulator of CNS homeostasis, neural synaptic plasticity and cognitive function.
D. Mastellos
2014Experimental Neurology40 citations
Semantic Scholar
3,4-diaminobenzoic acid derivatives as inhibitors of the oxytocinase subfamily of M1 aminopeptidases with immune-regulating properties.
A. Papakyriakou, E. Zervoudi, Sofia Tsoukalidou, François-Xavier Mauvais +6 more
2015Journal of Medicinal Chemistry39 citations Open access
Semantic Scholar
Expanding complement therapeutics for the treatment of paroxysmal nocturnal hemoglobinuria
D. Mastellos, E. Reis, Despina Yancopoulou, A. Risitano +1 more
2018Seminars in hematology (Print)36 citations Open access
Semantic Scholar
From discovery to approval: A brief history of the compstatin family of complement C3 inhibitors.
D. Mastellos, D. Ricklin, G. Sfyroera, A. Sahu
2021Clinical Immunology32 citations
Semantic Scholar
cDNA cloning and phylogenetic analysis of the sixth complement component in rainbow trout.
M. Chondrou, D. Mastellos, I. Zarkadis
2006Molecular Immunology32 citations
Semantic Scholar
Is complement the culprit behind COVID-19 vaccine-related adverse reactions?
D. Mastellos, P. Skendros, John D Lambris
2021Journal of Clinical Investigation31 citations Open access
Semantic Scholar
Complement: an inflammatory pathway fulfilling multiple roles at the interface of innate immunity and development.
D. Mastellos, A. E. Germenis, John D Lambris
2005Current drug targets. Inflammation & allergy28 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

John D Lambris×43
Invite
John D Lambris — researcher profile on SciRah
D. Ricklin×13
Invite
D. Ricklin — researcher profile on SciRah
Despina Yancopoulou×12
Invite
Despina Yancopoulou — researcher profile on SciRah
E. Reis×10
Invite
E. Reis — researcher profile on SciRah

G. Hajishengallis

×9

Invite

G. Hajishengallis — researcher profile on SciRah

Invite

A. Risitano — researcher profile on SciRah

M. Huber-Lang×6

Invite

M. Huber-Lang — researcher profile on SciRah

Invite

B. Nilsson — researcher profile on SciRah

Invite

P. Skendros — researcher profile on SciRah

Invite

K. Ritis — researcher profile on SciRah

M. Markiewski×4

Invite

M. Markiewski — researcher profile on SciRah

A. Chrysanthopoulou×3

Invite

A. Chrysanthopoulou — researcher profile on SciRah