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S. Espinoza · SciRah

Researcher profile · Semantic Scholar

S. Espinoza

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S. Espinoza — researcher profile on SciRah

h-index: 29
Works: 80
Citations: 2,858

Most-cited papers

Dopamine receptors – IUPHAR Review 13
J. Beaulieu, S. Espinoza, R. Gainetdinov
2015British Journal of Pharmacology489 citations Open access
Semantic Scholar
Functional Interaction between Trace Amine-Associated Receptor 1 and Dopamine D2 Receptor
S. Espinoza, A. Salahpour, B. Masri, T. D. Sotnikova +4 more
2011Molecular Pharmacology190 citations Open access
Semantic Scholar
Pronounced Hyperactivity, Cognitive Dysfunctions, and BDNF Dysregulation in Dopamine Transporter Knock-out Rats
D. Leo, I. Sukhanov, Francesca Zoratto, P. Illiano +17 more
2018Journal of Neuroscience186 citations Open access
Semantic Scholar
On the Origin of Extracellular Glutamate Levels Monitored in the Basal Ganglia of the Rat by In Vivo Microdialysis
M. Herrera-Marschitz, Z. You, M. Goiny, J. J. Meana +11 more
1996Journal of Neurochemistry178 citations
Semantic Scholar
Taar1-mediated modulation of presynaptic dopaminergic neurotransmission: role of D2 dopamine autoreceptors.
D. Leo, L. Mus, S. Espinoza, M. Hoener +2 more
2014Neuropharmacology143 citations
Semantic Scholar
BRET biosensors to study GPCR biology, pharmacology, and signal transduction
A. Salahpour, S. Espinoza, B. Masri, Vincent M. Lam +2 more
2012Front. Endocrin.125 citations Open access
Semantic Scholar
TAAR1 Modulates Cortical Glutamate NMDA Receptor Function
S. Espinoza, G. Lignani, L. Caffino, S. Maggi +14 more
2015Neuropsychopharmacology123 citations Open access
Semantic Scholar
The Dopamine Metabolite 3-Methoxytyramine Is a Neuromodulator
T. D. Sotnikova, J. Beaulieu, S. Espinoza, B. Masri +5 more
2010PLoS ONE99 citations Open access
Semantic Scholar
Postsynaptic D2 dopamine receptor supersensitivity in the striatum of mice lacking TAAR1.
S. Espinoza, V. Ghisi, M. Emanuele, D. Leo +4 more
2015Neuropharmacology98 citations
Semantic Scholar
Trace Amine-Associated Receptor 5 Provides Olfactory Input Into Limbic Brain Areas and Modulates Emotional Behaviors and Serotonin Transmission
S. Espinoza, I. Sukhanov, E. Efimova, A. Kozlova +10 more
2020Frontiers in Molecular Neuroscience74 citations Open access
Semantic Scholar
SINEUP Non-coding RNA Targeting GDNF Rescues Motor Deficits and Neurodegeneration in a Mouse Model of Parkinson’s Disease
S. Espinoza, M. Scarpato, Devid Damiani, F. Managò +10 more
2019Molecular Therapy61 citations Open access
Semantic Scholar
Trace amine-associated receptor 1: a multimodal therapeutic target for neuropsychiatric diseases
Michael D Schwartz, J. Canales, R. Zucchi, S. Espinoza +2 more
2018Expert opinion on therapeutic targets60 citations Open access
Semantic Scholar
Insights into the Structure and Pharmacology of the Human Trace Amine‐Associated Receptor 1 (hTAAR1): Homology Modelling and Docking Studies
E. Cichero, S. Espinoza, R. R. Gainetdinov, L. Brasili +1 more
2013Chemical Biology and Drug Design58 citations Open access
Semantic Scholar
Design, Synthesis, and Evaluation of Thyronamine Analogues as Novel Potent Mouse Trace Amine Associated Receptor 1 (mTAAR1) Agonists.
G. Chiellini, Giulia Nesi, M. Digiacomo, Rossella Malvasi +11 more
2015Journal of Medicinal Chemistry50 citations Open access
Semantic Scholar
Altered Sexual Behavior in Dopamine Transporter (DAT) Knockout Male Rats: A Behavioral, Neurochemical and Intracerebral Microdialysis Study
F. Sanna, J. Bratzu, M. Serra, D. Leo +6 more
2020Frontiers in Behavioral Neuroscience47 citations Open access
Semantic Scholar
TAAR1-dependent effects of apomorphine in mice.
I. Sukhanov, S. Espinoza, D. S. Yakovlev, M. Hoener +2 more
2014International Journal of Neuropsychopharmacology47 citations Open access
Semantic Scholar
Adenylyl cyclase activating polypeptide reduces phosphorylation and toxicity of the polyglutamine-expanded androgen receptor in spinobulbar muscular atrophy
M. J. Polanco, Sara Parodi, Diana Piol, Conor M. Stack +16 more
2016Science Translational Medicine45 citations
Semantic Scholar
Long-term optical stimulation of channelrhodopsin-expressing neurons to study network plasticity
G. Lignani, E. Ferrea, F. Difato, Jessica Amarù +6 more
2013Frontiers in Molecular Neuroscience44 citations Open access
Semantic Scholar
SINEUP non-coding RNAs rescue defective frataxin expression and activity in a cellular model of Friedreich's Ataxia
Carlotta Bon, Riccardo Luffarelli, R. Russo, S. Fortuni +13 more
2019Nucleic Acids Research42 citations Open access
Semantic Scholar
Neuronal hemoglobin affects dopaminergic cells' response to stress
Marta Codrich, M. Bertuzzi, R. Russo, Margherita Francescatto +10 more
2017Cell Death and Disease41 citations Open access
Semantic Scholar
Novel biguanide-based derivatives scouted as TAAR1 agonists: Synthesis, biological evaluation, ADME prediction and molecular docking studies.
M. Tonelli, S. Espinoza, R. Gainetdinov, E. Cichero
2017European journal of medicinal chemistry39 citations Open access
Semantic Scholar
Further Insights Into the Pharmacology of the Human Trace Amine‐Associated Receptors: Discovery of Novel Ligands for TAAR1 by a Virtual Screening Approach
E. Cichero, S. Espinoza, Silvia Franchini, Sara Guariento +3 more
2014Chemical Biology and Drug Design38 citations Open access
Semantic Scholar
Increased context-dependent conditioning to amphetamine in mice lacking TAAR1.
I. Sukhanov, L. Caffino, E. Efimova, S. Espinoza +4 more
2016Pharmacological Research36 citations
Semantic Scholar
Biochemical and Functional Characterization of the Trace Amine-Associated Receptor 1 (TAAR1) Agonist RO5263397
S. Espinoza, D. Leo, T. D. Sotnikova, M. Shahid +2 more
2018Frontiers in Pharmacology34 citations Open access
Semantic Scholar
Role of Dopamine D2/D3 Receptors in Development, Plasticity, and Neuroprotection in Human iPSC-Derived Midbrain Dopaminergic Neurons
Federica Bono, P. Savoia, Adele Guglielmi, M. Gennarelli +9 more
2017Molecular Neurobiology33 citations
Semantic Scholar
In-vivo pharmacology of Trace-Amine Associated Receptor 1.
Vincent M. Lam, S. Espinoza, A. Gerasimov, R. Gainetdinov +1 more
2015European Journal of Pharmacology33 citations
Semantic Scholar
Rational design, chemical synthesis and biological evaluation of novel biguanides exploring species-specificity responsiveness of TAAR1 agonists.
Sara Guariento, M. Tonelli, S. Espinoza, A. Gerasimov +2 more
2018European journal of medicinal chemistry30 citations Open access
Semantic Scholar
A homology modelling-driven study leading to the discovery of the first mouse trace amine-associated receptor 5 (TAAR5) antagonists
E. Cichero, S. Espinoza, M. Tonelli, Silvia Franchini +5 more
201629 citations Open access
Semantic Scholar
Role of catechol-O-methyltransferase (COMT)-dependent processes in Parkinson's disease and L-DOPA treatment.
S. Espinoza, F. Managò, D. Leo, T. D. Sotnikova +1 more
2012CNS and Neurological Disorders - Drug Targets29 citations
Semantic Scholar
SINEUPs: a novel toolbox for RNA therapeutics
S. Espinoza, Carlotta Bon, P. Valentini, Bianca Pierattini +10 more
2021Essays in Biochemistry26 citations Open access
Semantic Scholar
Hit-to-Lead Optimization of Mouse Trace Amine Associated Receptor 1 (mTAAR1) Agonists with a Diphenylmethane-Scaffold: Design, Synthesis, and Biological Study.
G. Chiellini, Giulia Nesi, S. Sestito, S. Chiarugi +11 more
2016Journal of Medicinal Chemistry26 citations Open access
Semantic Scholar
Correction: The Dopamine Metabolite 3-Methoxytyramine Is a Neuromodulator
T. D. Sotnikova, J. Beaulieu, S. Espinoza, B. Masri +5 more
2010PLoS ONE26 citations Open access
Semantic Scholar
Identification of TAAR5 Agonist Activity of Alpha-NETA and Its Effect on Mismatch Negativity Amplitude in Awake Rats
A. Aleksandrov, V. Knyazeva, A. Volnova, E. Dmitrieva +4 more
2018Neurotoxicity research22 citations
Semantic Scholar
BRET approaches to characterize dopamine and TAAR1 receptor pharmacology and signaling.
S. Espinoza, B. Masri, A. Salahpour, R. Gainetdinov
2013Methods in molecular biology22 citations
Semantic Scholar
The role of GRK6 in animal models of Parkinson's Disease and L-DOPA treatment
F. Managò, S. Espinoza, A. Salahpour, T. D. Sotnikova +3 more
2012Scientific Reports22 citations Open access
Semantic Scholar
Recombinant Adeno-Associated Virus-mediated rescue of function in a mouse model of Dopamine Transporter Deficiency Syndrome
P. Illiano, C. Bass, L. Fichera, L. Mus +5 more
2017Scientific Reports20 citations Open access
Semantic Scholar
Trace Amine Associate Receptor 1 (TAAR1) as a New Target for the Treatment of Cognitive Dysfunction in Alzheimer’s Disease
D. Leo, G. Targa, S. Espinoza, Agnès Villers +2 more
2022International Journal of Molecular Sciences19 citations Open access
Semantic Scholar
Discovery of Novel Trace Amine-Associated Receptor 5 (TAAR5) Antagonists Using a Deep Convolutional Neural Network
Carlotta Bon, T. Chern, E. Cichero, T. O'Brien +3 more
2022International Journal of Molecular Sciences17 citations Open access
Semantic Scholar
Functional interaction between Trace Amine Associated Receptor 1 (TAAR1) and dopamine D2 receptor
S. Espinoza, A. Salahpour, B. Masri, T. D. Sotnikova +4 more
201115 citations
Semantic Scholar
A Metabologenomic approach reveals alterations in the gut microbiota of a mouse model of Alzheimer’s disease
Francesco Favero, E. Barberis, M. Gagliardi, S. Espinoza +12 more
2022PLoS ONE14 citations Open access
Semantic Scholar
Improved cognitive performance in trace amine-associated receptor 5 (TAAR5) knock-out mice
S. Maggi, Carlotta Bon, S. Gustincich, Valter Tucci +2 more
2022Scientific Reports13 citations Open access
Semantic Scholar
Dopamine receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
J. Beaulieu, E. Borrelli, A. Carlsson, M. Caron +17 more
2019IUPHAR/BPS Guide to Pharmacology CITE12 citations Open access
Semantic Scholar
Neuronal Functions and Emerging Pharmacology of TAAR1
S. Espinoza, R. Gainetdinov
201412 citations
Semantic Scholar
SINEUP non-coding RNA activity depends on specific N6-methyladenosine nucleotides
Bianca Pierattini, S. D’Agostino, Carlotta Bon, Omar Peruzzo +11 more
2023Molecular Therapy: Nucleic Acids11 citations Open access
Semantic Scholar
Behavioral Effects of a Potential Novel TAAR1 Antagonist
Vincent M. Lam, C. Mielnik, C. Baimel, Pieter Beerepoot +7 more
2018Frontiers in Pharmacology10 citations Open access
Semantic Scholar
TAAR1 modulates cortical glutamate NMDA receptor function
S. Espinoza
201610 citations
Semantic Scholar
Antipsychotic-like effects of the N-methyl-D-aspartate receptor modulator neboglamine: an immunohistochemical and behavioural study in the rat.
R. Chiusaroli, P. Garofalo, S. Espinoza, E. Neri +2 more
2010Pharmacological Research10 citations
Semantic Scholar
Towards SINEUP-based therapeutics: Design of an in vitro synthesized SINEUP RNA
P. Valentini, Bianca Pierattini, E. Zacco, D. Mangoni +7 more
2022Molecular Therapy: Nucleic Acids9 citations Open access
Semantic Scholar
Neuronal haemoglobin induces loss of dopaminergic neurons in mouse Substantia nigra, cognitive deficits and cleavage of endogenous α-synuclein
Chiara Santulli, Carlotta Bon, Elena de Cecco, Marta Codrich +8 more
2022Cell Death and Disease8 citations Open access
Semantic Scholar
The after-hours circadian mutant has reduced phenotypic plasticity in behaviors at multiple timescales and in sleep homeostasis
S. Maggi, E. Balzani, G. Lassi, Celina García-García +9 more
2017Scientific Reports8 citations Open access
Semantic Scholar

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