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K. von Hoff · SciRah

Researcher profile · Semantic Scholar

K. von Hoff

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K. von Hoff — researcher profile on SciRah

h-index: 41
Works: 172
Citations: 11K

Most-cited papers

DNA methylation-based classification of central nervous system tumours
D. Capper, David T. W. Jones, M. Sill, V. Hovestadt +139 more
2018Nature2,577 citations Open access
Semantic Scholar
The landscape of genomic alterations across childhood cancers
S. Gröbner, Barbara C. Worst, J. Weischenfeldt, I. Buchhalter +80 more
2018Nature1,388 citations Open access
Semantic Scholar
Childhood cancer predisposition syndromes—A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology
T. Ripperger, S. Bielack, A. Borkhardt, I. Brecht +72 more
2017American Journal of Medical Genetics. Part A247 citations Open access
Semantic Scholar
Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.
V. Ramaswamy, T. Hielscher, S. Mack, Á. Lassaletta +111 more
2016Journal of Clinical Oncology173 citations Open access
Semantic Scholar
The Molecular Landscape of ETMR at Diagnosis and Relapse
S. Lambo, S. Gröbner, T. Rausch, S. Waszak +61 more
2019Nature124 citations Open access
Semantic Scholar
Evidence of H3 K27M mutations in posterior fossa ependymomas
M. Gessi, D. Capper, F. Sahm, Kristin Huang +14 more
2016Acta Neuropathologica83 citations
Semantic Scholar
Nonmetastatic Medulloblastoma of Early Childhood: Results From the Prospective Clinical Trial HIT-2000 and An Extended Validation Cohort.
M. Mynarek, K. von Hoff, T. Pietsch, H. Ottensmeier +45 more
2020Journal of Clinical Oncology76 citations Open access
Semantic Scholar
ETMR: a tumor entity in its infancy
S. Lambo, K. von Hoff, A. Korshunov, S. Pfister +1 more
2020Acta Neuropathologica75 citations Open access
Semantic Scholar
PATZ1 fusions define a novel molecularly distinct neuroepithelial tumor entity with a broad histological spectrum
K. Alhalabi, D. Stichel, P. Sievers, H. Peterziel +58 more
2021Acta Neuropathologica71 citations Open access
Semantic Scholar
Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations
E. Pfaff, C. Aichmüller, M. Sill, D. Stichel +25 more
2019Acta Neuropathologica71 citations Open access
Semantic Scholar
Clinical and molecular heterogeneity of pineal parenchymal tumors: a consensus study
A. Liu, Bryan Li, E. Pfaff, B. Gudenas +28 more
2020Acta Neuropathologica64 citations Open access
Semantic Scholar
Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort
S. Waszak, P. Northcott, I. Buchhalter, G. Robinson +83 more
2018The Lancet Oncology47 citations Open access
Semantic Scholar
A mouse model for embryonal tumors with multilayered rosettes uncovers the therapeutic potential of Sonic-hedgehog inhibitors
J. Neumann, Annika K. Wefers, S. Lambo, E. Bianchi +20 more
2017Nature Medicine43 citations
Semantic Scholar
CDKN2A deletion in supratentorial ependymoma with RELA alteration indicates a dismal prognosis: a retrospective analysis of the HIT ependymoma trial cohort
Stephanie T. Jünger, F. Andreiuolo, M. Mynarek, I. Wohlers +12 more
2020Acta Neuropathologica40 citations Open access
Semantic Scholar
Amplification of the PLAG-family genes—PLAGL1 and PLAGL2—is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification
M. Keck, M. Sill, A. Wittmann, P. Joshi +52 more
2022Acta Neuropathologica37 citations Open access
Semantic Scholar
Advancing CNS tumor diagnostics with expanded DNA methylation-based classification.
M. Sill, D. Schrimpf, Areeba Patel, D. Sturm +117 more
2025Cancer Cell35 citations Open access
Semantic Scholar
Therapeutic implications of improved molecular diagnostics for rare CNS-embryonal tumor entities: results of an international, retrospective study.
K. von Hoff, C. Haberler, Felix Schmitt-Hoffner, Elizabeth Schepke +57 more
2021Neuro-Oncology35 citations Open access
Semantic Scholar
Functional loss of a noncanonical BCOR–PRC1.1 complex accelerates SHH-driven medulloblastoma formation
L. Kutscher, K. Okonechnikov, N. Batora, Jessica Clark +23 more
2020bioRxiv30 citations Open access
Semantic Scholar
MRI Phenotype of RELA-fused Pediatric Supratentorial Ependymoma
J. Nowak, S. T. Jünger, H. Huflage, C. Seidel +6 more
2018Clinical Neuroradiology30 citations
Semantic Scholar
Newly Diagnosed Metastatic Intracranial Ependymoma in Children: Frequency, Molecular Characteristics, Treatment, and Outcome in the Prospective HIT Series.
M. Benesch, M. Mynarek, H. Witt, M. Warmuth-Metz +22 more
2019The Oncologist28 citations Open access
Semantic Scholar
Local and Systemic Therapy of Recurrent Ependymoma in Children and Adolescents: Short- and Long-term Results of the E-HIT-REZ 2005 Study.
Jonas E. Adolph, G. Fleischhack, Ruth Mikasch, J. Zeller +20 more
2020Neuro-Oncology27 citations Open access
Semantic Scholar
Author Correction: The landscape of genomic alterations across childhood cancers
S. Gröbner, Barbara C. Worst, J. Weischenfeldt, I. Buchhalter +80 more
2018Nature24 citations Open access
Semantic Scholar
Pediatric pineoblastoma: A pooled outcome study of North American and Australian therapeutic data
J. Hansford, Jie Huang, R. Endersby, A. Dodgshun +18 more
2022Neuro-Oncology Advances22 citations Open access
Semantic Scholar
Treatment of children under 4 years of age with medulloblastoma and ependymoma in the HIT2000/HIT-REZ 2005 trials: Neuropsychological outcome 5 years after treatment
H. Ottensmeier, P. Schlegel, M. Eyrich, J. Wolff +15 more
2020PLoS ONE21 citations Open access
Semantic Scholar
Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts
M. Mynarek, D. Obrecht, M. Sill, D. Sturm +20 more
2022Acta Neuropathologica20 citations Open access
Semantic Scholar
Evaluation of Prognostic Factors and Role of Participation in a Randomized Trial or a Prospective Registry in Pediatric and Adolescent Nonmetastatic Medulloblastoma – A Report From the HIT 2000 Trial
S. Dietzsch, Felix Placzek, K. Pietschmann, A. V. von Bueren +34 more
2020Advances in Radiation Oncology20 citations Open access
Semantic Scholar
Improved risk-stratification for posterior fossa ependymoma of childhood considering clinical, histological and genetic features – a retrospective analysis of the HIT ependymoma trial cohort
Stephanie T. Jünger, M. Mynarek, I. Wohlers, Evelyn Dörner +11 more
2019Acta Neuropathologica Communications20 citations Open access
Semantic Scholar
Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome.
A. Kolodziejczak, L. Guerrini-Rousseau, J. M. Planchon, J. Ecker +69 more
2023Neuro-Oncology19 citations Open access
Semantic Scholar
Treatment of Embryonal Tumours with Multilayered Rosettes with Carboplatin/Etoposide Induction and High-dose Chemotherapy within the Prospective P-HIT Trial.
B. Juhnke, M. Gessi, N. Gerber, Carsten Friedrich +15 more
2021Neuro-Oncology19 citations Open access
Semantic Scholar
Advancing CNS tumor diagnostics with expanded DNA methylation-based classification
M. Sill, D. Schrimpf, Areeba Patel, D. Sturm +117 more
2025medRxiv18 citations Open access
Semantic Scholar
Biological material collection to advance translational research and treatment of children with CNS tumours: position paper from the SIOPE Brain Tumour Group.
S. Rutkowski, P. Modena, D. Williamson, K. Kerl +29 more
2018The Lancet Oncology18 citations Open access
Semantic Scholar
Quality of survival and cognitive performance in children treated for medulloblastoma in the PNET 4 randomized controlled trial.
H. Câmara-Costa, K. Bull, C. Kennedy, A. Wiener +14 more
2017Neuro-Oncology Practice14 citations Open access
Semantic Scholar
Rapid DNA methylation-based classification of pediatric brain tumors from ultrasonic aspirate specimens
M. Simon, L. P. Kuschel, K. von Hoff, D. Yuan +7 more
2023bioRxiv11 citations Open access
Semantic Scholar
A multi-institutional retrospective pooled outcome analysis of molecularly annotated pediatric supratentorial ZFTA-fused ependymoma
C. Ng, D. Obrecht, O. Wells, M. Zápotocký +26 more
2023Neuro-Oncology Advances10 citations Open access
Semantic Scholar
PLAG1 fusions define a third subtype of CNS embryonal tumor with PLAG family gene alteration
Michaela-Kristina Keck, M. Al-Hussaini, N. Amayiri, A. B. Yiadom +32 more
2025Acta Neuropathologica9 citations Open access
Semantic Scholar
Risk factors for domain-specific neurocognitive outcome in pediatric survivors of a brain tumor in the posterior fossa - Results of the HIT 2000 trial.
M. Mynarek, Anne Rossius, Anika Guiard, H. Ottensmeier +19 more
2024Neuro-Oncology9 citations Open access
Semantic Scholar
Evidence of neural crest cell origin of a DICER1 mutant CNS sarcoma in a child with DICER1 syndrome and NRAS‐mutant neurocutaneous melanosis
L. Schweizer, W. Hartmann, A. Koch, Maximilian Nunninger +12 more
2022Neuropathology and Applied Neurobiology9 citations Open access
Semantic Scholar
Clinically relevant molecular hallmarks of PFA ependymomas display intratumoral heterogeneity and correlate with tumor morphology
Swenja Gödicke, C. Kresbach, M. Ehlert, D. Obrecht +13 more
2024Acta Neuropathologica8 citations Open access
Semantic Scholar
Radiotherapy plays an important role in the treatment of atypical teratoid/rhabdoid tumors - analysis of the EU-RHAB cohorts and their precursors.
S. Frisch, Hanna Libuschewski, S. Peters, Joachim Gerss +8 more
2024International Journal of Radiation Oncology, Biology, Physics8 citations Open access
Semantic Scholar
Refining M1 stage in medulloblastoma: criteria for cerebrospinal fluid cytology and implications for improved risk stratification from the HIT-2000 trial.
C. Hagel, Veronika Sloman, M. Mynarek, K. Petrasch +14 more
2022European Journal of Cancer8 citations Open access
Semantic Scholar
Developing an advanced risk stratification model for pediatric intracranial ependymoma based on the prospective trial E-HIT2000 and subsequent registries.
K. von Hoff, Denise Obrecht-Sturm, David R. Ghasemi, Janna Wenning +49 more
2025Neuro-Oncology6 citations Open access
Semantic Scholar
CNS Embryonal Tumor with PLAGL Amplification, a New Tumor in Children and Adolescents: Insights from a Comprehensive MRI Analysis
A. Tietze, B. Bison, J. Engelhardt, T. Fenouil +19 more
2024American Journal of Neuroradiology6 citations Open access
Semantic Scholar
Risk prediction in early childhood SHH medulloblastoma treated with radiation-avoiding chemotherapy: Evidence for more than two subgroups.
Svenja Tonn, A. Korshunov, D. Obrecht, M. Sill +22 more
2023Neuro-Oncology6 citations Open access
Semantic Scholar
Distinct relapse pattern across molecular ependymoma types.
Denise Obrecht-Sturm, M. Schoof, Alicia Eckhardt, M. Mynarek +23 more
2024Neuro-Oncology5 citations
Semantic Scholar
Comparative Clinical and Imaging‐Based Evaluation of Therapeutic Modalities in CNS Embryonal Tumours With PLAGL Amplification
Michaela-Kristina Keck, A. Tietze, B. Bison, Shivaram Avula +33 more
2025Neuropathology and Applied Neurobiology4 citations Open access
Semantic Scholar
MBCL-07. NON-METASTATIC MEDULLOBLASTOMA OF EARLY CHILDHOOD: RESULTS FROM THE PROSPECTIVE CLINICAL TRIAL HIT-2000 AND AN EXTENDED VALIDATION COHORT
M. Mynarek, K. von Hoff, T. Pietsch, H. Ottensmeier +44 more
2020Neuro-Oncology4 citations Open access
Semantic Scholar
ETMR-06. PNOC031 - INTERNATIONAL TRIAL FOR EMBRYONAL TUMOR WITH MULTILAYERED ROSETTES
Derek Hanson, Susan N. Chi, S. Braunstein, H. Elhalawani +10 more
2024Neuro-Oncology3 citations Open access
Semantic Scholar
Correction to: Amplification of the PLAG-family genes—PLAGL1 and PLAGL2—is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification
M. Keck, M. Sill, A. Wittmann, P. Joshi +52 more
2023Acta Neuropathologica3 citations Open access
Semantic Scholar
Focal versus craniospinal radiation for disseminated atypical teratoid/rhabdoid tumor following favorable response to systemic therapy
P. Aridgides, A. Mahajan, B. Eaton, Dong-Liang Wang +9 more
2023Pediatric Blood & Cancer3 citations
Semantic Scholar
Clinical and molecular characterization of isolated M1 disease in pediatric medulloblastoma: experience from the German HIT-MED studies
D. Obrecht, M. Mynarek, C. Hagel, R. Kwiecien +20 more
2022Journal of Neuro-Oncology3 citations Open access
Semantic Scholar

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S. Rutkowski×33
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S. Pfister×26
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S. Pfister — researcher profile on SciRah
M. Mynarek×23
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M. Mynarek — researcher profile on SciRah
U. Schüller×22
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M. Kool — researcher profile on SciRah

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T. Pietsch — researcher profile on SciRah

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F. Sahm — researcher profile on SciRah

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G. Fleischhack — researcher profile on SciRah

A. von Deimling×17

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D. Sturm — researcher profile on SciRah