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H. Peterziel · SciRah

Researcher profile · Semantic Scholar

H. Peterziel

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H. Peterziel — researcher profile on SciRah

h-index: 12
Works: 68
Citations: 532

Most-cited papers

PATZ1 fusions define a novel molecularly distinct neuroepithelial tumor entity with a broad histological spectrum
K. Alhalabi, D. Stichel, P. Sievers, H. Peterziel +58 more
2021Acta Neuropathologica71 citations Open access
Semantic Scholar
Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORM
H. Peterziel, N. Jamaladdin, Dina Elharouni, Xenia F. Gerloff +42 more
2022npj Precision Oncology66 citations Open access
Semantic Scholar
Three-dimensional tumor cell growth stimulates autophagic flux and recapitulates chemotherapy resistance
C. Bingel, E. Koeneke, J. Ridinger, A. Bittmann +10 more
2017Cell Death and Disease53 citations Open access
Semantic Scholar
Dual role of HDAC10 in lysosomal exocytosis and DNA repair promotes neuroblastoma chemoresistance
J. Ridinger, E. Koeneke, Fiona R. Kolbinger, Katharina Koerholz +9 more
2018Scientific Reports47 citations Open access
Semantic Scholar
The first-in-class ERK inhibitor ulixertinib shows promising activity in MAPK-driven pediatric low-grade glioma models.
R. Sigaud, Lisa Rösch, Charlotte Gatzweiler, Julia Benzel +25 more
2022Neuro-Oncology35 citations Open access
Semantic Scholar
BH3 mimetics targeting BCL-XL impact the senescent compartment of pilocytic astrocytoma.
F. Selt, R. Sigaud, G. Valinciute, P. Sievers +24 more
2022Neuro-Oncology32 citations Open access
Semantic Scholar
Functional Therapeutic Target Validation Using Pediatric Zebrafish Xenograft Models
Charlotte Gatzweiler, J. Ridinger, Sonja Herter, Xenia F. Gerloff +23 more
2022Cancers29 citations Open access
Semantic Scholar
A kinome-wide RNAi screen identifies ALK as a target to sensitize neuroblastoma cells for HDAC8-inhibitor treatment
Jing-yan Shen, S. Najafi, Sina Stäble, J. Fabian +14 more
2018Cell Death and Differentiation28 citations Open access
Semantic Scholar
Broad-Spectrum HDAC Inhibitors Promote Autophagy through FOXO Transcription Factors in Neuroblastoma
Katharina Körholz, J. Ridinger, D. Krunic, S. Najafi +7 more
2021Cells27 citations Open access
Semantic Scholar
Rapid In Vivo Validation of HDAC Inhibitor-Based Treatments in Neuroblastoma Zebrafish Xenografts
Jagoda K. Wrobel, S. Najafi, Simay Ayhan, Charlotte Gatzweiler +9 more
2020Pharmaceuticals27 citations Open access
Semantic Scholar
iTReX: Interactive exploration of mono- and combination therapy dose response profiling data.
Dina Elharouni, Yannick Berker, H. Peterziel, Apurva Gopisetty +9 more
2021Pharmacological Research23 citations Open access
Semantic Scholar
Key Pharmacokinetic Parameters of 74 Pediatric Anticancer Drugs Providing Assistance in Preclinical Studies
N. Jamaladdin, R. Sigaud, Daniela Kocher, A. Kolodziejczak +10 more
2023Clinical pharmacology and therapy12 citations Open access
Semantic Scholar
Patient-by-Patient Deep Transfer Learning for Drug-Response Profiling Using Confocal Fluorescence Microscopy of Pediatric Patient-Derived Tumor-Cell Spheroids
Yannick Berker, Dina Elharouni, H. Peterziel, P. Fiesel +4 more
2022IEEE Transactions on Medical Imaging12 citations Open access
Semantic Scholar
Combining APR-246 and HDAC-Inhibitors: A Novel Targeted Treatment Option for Neuroblastoma
Michael Müller, Lisa Rösch, S. Najafi, Charlotte Gatzweiler +13 more
2021Cancers12 citations Open access
Semantic Scholar
Combination drug screen identifies synergistic drug interaction of BCL-XL and class I histone deacetylase inhibitors in MYC-amplified medulloblastoma cells
Simon Zeuner, J. Vollmer, R. Sigaud, Sina Oppermann +6 more
2024Journal of Neuro-Oncology10 citations Open access
Semantic Scholar
ERBB and P‐glycoprotein inhibitors break resistance in relapsed neuroblastoma models through P‐glycoprotein
Lisa Rösch, Sonja Herter, S. Najafi, J. Ridinger +6 more
2022Molecular Oncology8 citations Open access
Semantic Scholar
Predictive modeling of resistance to SMO inhibition in a patient-derived orthotopic xenograft model of SHH medulloblastoma
Sonja Krausert, S. Brabetz, Norman Mack, Felix Schmitt-Hoffner +11 more
2022Neuro-Oncology Advances8 citations Open access
Semantic Scholar
Synergy of retinoic acid and BH3 mimetics in MYC(N)-driven embryonal nervous system tumours
T. Seiboldt, Constantia Zeiser, Duy Nguyen, Simay Celikyürekli +15 more
2024British Journal of Cancer7 citations Open access
Semantic Scholar
Somatic gene delivery faithfully recapitulates a molecular spectrum of high-risk sarcomas
R. Imle, Daniel Blösel, Felix K. F. Kommoss, Sara Placke +28 more
2025Nature Communications6 citations Open access
Semantic Scholar
High content-imaging drug synergy screening identifies specific senescence-related vulnerabilities of mesenchymal neuroblastomas
Sonja Herter, M. Emperador, Kyriaki Smyrilli, Daniela Kocher +13 more
2025Cell Death and Disease5 citations Open access
Semantic Scholar
Integrative Multiomics and Drug Sensitivity Profiling Reveal Potential Biomarkers and Therapeutic Strategies in Pediatric Solid Tumors
Dina Elharouni, Rosa Hernansaiz-Ballesteros, H. Peterziel, G. Balasubramanian +13 more
2025Cancer Research5 citations
Semantic Scholar
Class I HDAC inhibition reduces DNA damage repair capacity of MYC-amplified medulloblastoma cells
J. Vollmer, J. Ecker, T. Hielscher, G. Valinciute +7 more
2023Journal of Neuro-Oncology4 citations Open access
Semantic Scholar
Chromosome 8 gain drives cancer progression by hijacking the translation factor 4E-BP1 sensitizing for targeted CDK4/6 inhibition
C. Funk, Anna C. Ehlers, M. F. Orth, Karim Aljakouch +30 more
2024bioRxiv3 citations Open access
Semantic Scholar
Evaluation of Antitumor and On-Target Activity of HDAC Inhibitors with the Zebrafish Embryo Xenograft Model.
Charlotte Gatzweiler, J. Ridinger, Simay Ayhan, S. Najafi +3 more
2023Methods in molecular biology3 citations
Semantic Scholar
Somatic gene delivery for flexible in vivo modeling of high-risk sarcoma
R. Imle, Daniel Blösel, F. Kommoss, Eric Zhao +25 more
2024bioRxiv2 citations Open access
Semantic Scholar
Integration and validation of complementary ex vivo assays for functional precision oncology
Anna Loboda, J. Paluncic, M. Freitas, Marko Weidmann +17 more
2026npj Precision Oncology1 citations Open access
Semantic Scholar
Glutaredoxin 3 (GLRX3) confers a fusion oncogene-dependent vulnerability to Ewing sarcoma
Endrit Vinca, Anna C. Ehlers, Alina Ritter, David Obermeier +21 more
2024bioRxiv1 citations Open access
Semantic Scholar
EPEN-20. LEVERAGING ABERRANT EXTRACELLULAR VESICLE SIGNALING FOR TARGETED DRUG REPURPOSING IN PEDIATRIC EPENDYMOMA
K. Maass, Johanna Rettenmeier, J. Sundheimer, M. Roosen +20 more
2024Neuro-Oncology1 citations Open access
Semantic Scholar
Abstract 5221: The first-in-class ERK inhibitor ulixertinib (BVD-523) shows activity in MAPK-driven pediatric low-grade glioma models as single agent and in combination with MEK inhibitors or senolytics
R. Sigaud, Lisa Rösch, Charlotte Gatzweiler, Julia Benzel +19 more
2022Cancer Research1 citations
Semantic Scholar
MODL-15. High-throughput combination drug screening identifies synergism between retinoic acid treatment and BCL-XL-inhibition in MYC(N)-driven medulloblastoma and neuroblastoma models
T. Seiboldt, Constantia Zeiser, Rabia Salem-Altintas, D. Nguyen +4 more
2022Neuro-Oncology1 citations Open access
Semantic Scholar
LGG-25. The first-in-class ERK inhibitor ulixertinib (BVD-523) shows activity in MAPK-driven pediatric low-grade glioma models as single agent and in combination with MEK inhibitors or senolytics
R. Sigaud, Lisa Rösch, Charlotte Gatzweiler, Julia Benzel +21 more
2022Neuro-Oncology1 citations Open access
Semantic Scholar
Cytotoxic activity of selinexor in BRAFV600E-driven pediatric low-grade glioma 3D cultures
Constantia Zeiser, M. Emperador, Sonja Herter, Lisa Sigaud +18 more
2026Acta Neuropathologica Communications0 citations Open access
Semantic Scholar
Ependymoma group-specific blood-brain barrier differences uncovered by a multi-omics approach
J. Sundheimer, Julia Benzel, A. Federico, S. Volz +19 more
2026Scientific Reports0 citations Open access
Semantic Scholar
CpG hypermethylation and WNT/AP-1 cooperativity define the epigenetic landscape and a clinical subgroup of high-risk pediatric adrenocortical carcinoma
V. Fincke, Maurice Loßner, M. Kunstreich, N. Reitsam +25 more
2026Nature Communications0 citations Open access
Semantic Scholar
Sensitivity profiling reveals consistent drug responses across preclinical neuroblastoma models
Marlinde C. Schoonbeek, Marloes van Luik, H. Peterziel, D. Gürgen +26 more
2026bioRxiv0 citations
Semantic Scholar
BH3-mimetics to overcome radioresistance in pediatric ependymoma
L. Bamberg, J. Schmiedel, E. Brost, H. Peterziel +6 more
2026Klinische Pädiatrie0 citations
Semantic Scholar
ID #824 Innovative precision-guided MAPK inhibition: expanding therapeutic benefits in pediatric glioma
G. Tax, Jie Mao, R. Cadiz, H. Peterziel +17 more
2026Neuro-Oncology Pediatrics0 citations Open access
Semantic Scholar
EPEN-08. Combinatorial screening approach to identify radiosensitizers in aggressive ependymoma
L. Bamberg, J. Sundheimer, Selina Faoual, Sonja Herter +14 more
2025Neuro-Oncology Pediatrics0 citations Open access
Semantic Scholar
EPEN-11. Understanding and overcoming mechanisms of dormancy in ependymoma
T. Fischer, L. Bamberg, J. Sundheimer, K. Okonechnikov +15 more
2025Neuro-Oncology Pediatrics0 citations Open access
Semantic Scholar
Abstract B006: Employing fresh tumor samples and long-term cultures for personalized drug response profiling in childhood solid cancers
L. Becker, Anna Loboda, K. Schramm, R. Autry +6 more
2025Cancer Research0 citations
Semantic Scholar
High 4E-BP1 expression associates with chromosome 8 gain and CDK4/6 sensitivity in Ewing sarcoma
C. Funk, Anna C. Ehlers, M. F. Orth, Karim Aljakouch +31 more
2025Journal of Clinical Investigation0 citations Open access
Semantic Scholar
Remission instead of eradication? MEK inhibition in primary refractory childhood LCH
Alexander Desuki, C. Paret, I. Oehme, H. Peterziel +12 more
2025Blood0 citations
Semantic Scholar
DMG-10. Synergistic CDK9 and BET inhibition overcomes therapeutic resistance in H3K27M pediatric diffuse midline gliomas by reprogramming DNA damage response
Simay Celikyurekli, T. Holland-Letz, Duy Nguyen, S. Calderazzo +6 more
2025Neuro-Oncology Pediatrics0 citations Open access
Semantic Scholar
Development of a ROS- and lysosome-addressing combination treatment for relapsed Neuroblastoma
K. Smyrilli, S. Herter, M. Emperador, H. Peterziel +4 more
2025Klinische Pädiatrie0 citations
Semantic Scholar
New cell lines expanding the diversity of Ewing sarcoma models
Maximilian Kerkhoff, C. Schaefer, W. Dirks, Dawid Krzeciesa +10 more
2025International Journal of Cancer0 citations
Semantic Scholar
Clinical evaluation of ex vivo drug sensitivity profiling in the pediatric precision oncology program INFORM
A. Schmidt, H. Peterziel, L. Becker, R. Autry +4 more
2025Klinische Pädiatrie0 citations
Semantic Scholar
Abstract A013: Functional profiling in pediatric precision medicine: global collaboration to drive clinical implementation
E. Looze, Jie Mao, H. Peterziel, Marlinde C. Schoonbeek +10 more
2025Cancer Research0 citations
Semantic Scholar
Abstract 7203: Systematic pan-cancer functional patient stratification to advance therapy personalization in rare solid tumors
J. Paluncic, Z. Carrero, Juliana Schulz, Attila Jády +27 more
2025Cancer Research0 citations
Semantic Scholar
Preclinical drug screen identifies WEE1 inhibitor and vinca alkaloid as a combination treatment concept for Li-Fraumeni syndrome medulloblastoma
A. Kolodziejczak, F. Selt, H. Peterziel, N. Jamaladdin +21 more
2025iScience0 citations
Semantic Scholar
HGG-14. COMPARING THE RADIOSENSITIZATION POTENTIAL OF VARIOUS COMPOUND CLASSES IN PEDIATRIC-TYPE DIFFUSE HIGH-GRADE GLIOMA
Alessia Cais, S. Lipiec, Kenneth Chun-Ho Chan, Nina Hofmann +16 more
2024Neuro-Oncology0 citations Open access
Semantic Scholar

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