Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

S. Mack · SciRah

Researcher profile · Semantic Scholar

S. Mack

Share profile

S. Mack — researcher profile on SciRah

h-index: 54
Works: 157
Citations: 15K

Most-cited papers

Childhood Cerebellar Tumors Mirror Conserved Fetal Transcriptional Programs
Maria C. Vladoiu, Ibrahim El-Hamamy, L. Donovan, H. Farooq +35 more
2019Nature370 citations Open access
Semantic Scholar
Targeting Glioma Stem Cells through Combined BMI1 and EZH2 Inhibition
Xun Jin, Leo J. Y. Kim, Qiulian Wu, Lisa C. Wallace +13 more
2017Nature Medicine334 citations Open access
Semantic Scholar
Divergent clonal selection dominates medulloblastoma at recurrence
A. Morrissy, L. Garzia, D. Shih, S. Zuyderduyn +134 more
2016Nature322 citations Open access
Semantic Scholar
Functional enhancers shape extrachromosomal oncogene amplifications
A. Morton, Nergiz Dogan-Artun, Z. Faber, G. Macleod +15 more
2019Cell297 citations Open access
Semantic Scholar
N6-methyladenine DNA Modification in Glioblastoma
Qi Xie, Tao P. Wu, R. Gimple, Zheng Li +25 more
2018Cell272 citations Open access
Semantic Scholar
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock
Zhen Dong, Guoxin Zhang, Meng Qu, R. Gimple +16 more
2019Cancer Discovery255 citations Open access
Semantic Scholar
AMPK/FIS1-mediated mitophagy is required for self-renewal of human AML stem cells
Shanshan Pei, Mohammad Minhajuddin, Biniam Adane, Nabilah Khan +14 more
2018Cell Stem Cell254 citations Open access
Semantic Scholar
Reciprocal signaling between Glioblastoma Stem Cells and Differentiated Tumor Cells Promotes Malignant Progression
Xiu-Xing Wang, B. Prager, Qiulian Wu, Leo J Y Kim +25 more
2018Cell Stem Cell233 citations Open access
Semantic Scholar
Locoregional delivery of CAR T-cells to the cerebrospinal fluid for treatment of metastatic medulloblastoma and ependymoma
L. Donovan, A. Delaidelli, Sujith K. Joseph, K. Bielamowicz +52 more
2020Nature Medicine206 citations Open access
Semantic Scholar
Therapeutic Targeting of Ependymoma as Informed by Oncogenic Enhancer Profiling
S. Mack, K. Pajtler, L. Chavez, K. Okonechnikov +71 more
2017Nature200 citations Open access
Semantic Scholar
Transcription elongation factors represent in vivo cancer dependencies in glioblastoma
Tyler E. Miller, Brian B Liau, Lisa C. Wallace, A. Morton +20 more
2017Nature190 citations Open access
Semantic Scholar
Purine synthesis promotes maintenance of brain tumor initiating cells in glioma
Xiu-Xing Wang, Kailin Yang, Qi Xie, Qiulian Wu +18 more
2017Nature Neuroscience189 citations Open access
Semantic Scholar
Therapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.
V. Ramaswamy, T. Hielscher, S. Mack, Á. Lassaletta +111 more
2016Journal of Clinical Oncology173 citations Open access
Semantic Scholar
Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells
Xiu-Xing Wang, Kailin Yang, Qiulian Wu, Leo J Y Kim +18 more
2019Science Translational Medicine172 citations Open access
Semantic Scholar
Histone H3.3G34-mutant interneuron progenitors co-opt PDGFRA for gliomagenesis
Carol C. L. Chen, Shriya Deshmukh, Selin Jessa, D. Hadjadj +60 more
2020Cell148 citations Open access
Semantic Scholar
Glioma Stem Cell Specific Super Enhancer Promotes Polyunsaturated Fatty Acid Synthesis to Support EGFR Signaling
R. Gimple, Reilly L. Kidwell, Leo J. Y. Kim, Teng-Qian Sun +23 more
2019Cancer Discovery145 citations Open access
Semantic Scholar
Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas
Brian Krug, N. De Jay, A. Harutyunyan, Shriya Deshmukh +24 more
2019Cancer Cell144 citations Open access
Semantic Scholar
Deubiquitinase USP13 maintains glioblastoma stem cells by antagonizing FBXL14-mediated Myc ubiquitination
X. Fang, Wenchao Zhou, Qiulian Wu, Zhi Huang +13 more
2017Journal of Experimental Medicine143 citations Open access
Semantic Scholar
Spatial heterogeneity in medulloblastoma
A. Morrissy, F. Cavalli, M. Remke, V. Ramaswamy +75 more
2017Nature Genetics126 citations Open access
Semantic Scholar
Nicotinamide metabolism regulates glioblastoma stem cell maintenance.
Jinkyu Jung, Leo J. Y. Kim, Xiu-Xing Wang, Qiulian Wu +7 more
2017JCI Insight120 citations Open access
Semantic Scholar
Chromatin landscapes reveal developmentally encoded transcriptional states that define human glioblastoma
S. Mack, I. Singh, Xiu-Xing Wang, Rachel A. Hirsch +23 more
2019Journal of Experimental Medicine118 citations Open access
Semantic Scholar
Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma
K. Michealraj, Sachin A. Kumar, Leo J Y Kim, F. Cavalli +62 more
2020Cell113 citations Open access
Semantic Scholar
Hotspots of aberrant enhancer activity punctuate the colorectal cancer epigenome
Andrea J. Cohen, Alina R. Saiakhova, Olivia Corradin, Jennifer M. Luppino +15 more
2017Nature Communications111 citations Open access
Semantic Scholar
MYC-regulated Mevalonate Metabolism Maintains Brain Tumor Initiating Cells
Xiu-Xing Wang, Zhi Huang, Qiulian Wu, B. Prager +17 more
2017Cancer Research110 citations Open access
Semantic Scholar
Heterogeneity within the PF-EPN-B Ependymoma Subgroup
F. Cavalli, Jens-Martin Hübner, T. Sharma, B. Luu +53 more
2018Acta Neuropathologica99 citations Open access
Semantic Scholar
K27M in canonical and noncanonical H3 variants occurs in distinct oligodendroglial cell lineages in brain midline gliomas
Selin Jessa, Abdulshakour Mohammadnia, A. Harutyunyan, Maud Hulswit +30 more
2022Nature Genetics93 citations Open access
Semantic Scholar
A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor.
P. Sin‐Chan, Iqra Mumal, Tannu Suwal, Ben Ho +50 more
2019Cancer Cell74 citations Open access
Semantic Scholar
ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma
A. Arabzade, Yan-Hua Zhao, S. Varadharajan, Hsiao-Chi Chen +37 more
2021Cancer Discovery70 citations Open access
Semantic Scholar
OpenPBTA: The Open Pediatric Brain Tumor Atlas
Joshua A. Shapiro, Krutika S. Gaonkar, S. Spielman, Candace Savonen +62 more
2023Cell Genomics62 citations Open access
Semantic Scholar
Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome
B. Golbourn, Matthew E. Halbert, Katharine E. Halligan, S. Varadharajan +45 more
2022Nature Cancer56 citations Open access
Semantic Scholar
Cross-species genomics reveals oncogenic dependencies in ZFTA/C11orf95 fusion-positive supratentorial ependymomas.
T. Zheng, David R. Ghasemi, K. Okonechnikov, A. Korshunov +45 more
2021Cancer Discovery56 citations Open access
Semantic Scholar
H3 K27M mutations are extremely rare in posterior fossa group A ependymoma
S. Ryall, Miguel A. Guzmán, S. Elbabaa, B. Luu +5 more
2017Child's Nervous System52 citations
Semantic Scholar
Childhood Medulloblastoma: Current Therapies, Emerging Molecular Landscape and Newer Therapeutic Insights
S. Khatua, A. Song, Divyaswathi Citla Sridhar, S. Mack
2018Current Neuropharmacology49 citations Open access
Semantic Scholar
ZFTA-translocations constitute ependymoma chromatin remodeling and transcription factors
R. Kupp, Lisa Ruff, Sabrina Terranova, E. Nathan +20 more
2021Cancer Discovery47 citations Open access
Semantic Scholar
Dual role of CXCL8 in maintaining the mesenchymal state of glioblastoma stem cells and M2-like tumor-associated macrophages.
Wei Yuan, Qian Zhang, Danling Gu, Chen-Fei Lu +39 more
2023Clinical Cancer Research42 citations Open access
Semantic Scholar
Cancer-predicting transcriptomic and epigenetic signatures revealed for ulcerative colitis in patient-derived epithelial organoids
S. K. Sarvestani, S. Signs, V. Lefebvre, S. Mack +14 more
2018OncoTarget36 citations Open access
Semantic Scholar
H3.3G34W promotes growth and impedes differentiation of osteoblast-like mesenchymal progenitors in Giant Cell Tumour of Bone
Sima Khazaei, N. De Jay, Shriya Deshmukh, Liam D. Hendrikse +27 more
2020Cancer Discovery32 citations Open access
Semantic Scholar
The Meningioma Enhancer Landscape Delineates Novel Subgroups and Drives Druggable Dependencies
B. Prager, H. Vasudevan, Deobrat Dixit, Jean A. Bernatchez +20 more
2020Cancer Discovery32 citations Open access
Semantic Scholar
A neurodevelopmental epigenetic programme mediated by SMARCD3–DAB1–Reelin signalling is hijacked to promote medulloblastoma metastasis
Han Zou, Brad Poore, Emily Brown, Jieqi Qian +36 more
2023Nature Cell Biology31 citations Open access
Semantic Scholar
Genomic Analysis of Childhood Brain Tumors: Methods for Genome-Wide Discovery and Precision Medicine Become Mainstream.
S. Mack, P. Northcott
2017Journal of Clinical Oncology30 citations
Semantic Scholar
SREBP2 maintains glioblastoma stem cells through keeping the balance between cholesterol biosynthesis and uptake.
Danling Gu, Feng-Qi Zhou, Hao You, Jiancheng Gao +26 more
2023Neuro-Oncology29 citations Open access
Semantic Scholar
Impact of radiation therapy and extent of resection for ependymoma in young children: A population‐based study
C. Snider, K. Yang, S. Mack, J. H. Suh +3 more
2018Pediatric Blood & Cancer26 citations
Semantic Scholar
Put away your microscopes: The ependymoma molecular era has begun
S. Mack, Michael D. Taylor
2017Current Opinion in Oncology23 citations Open access
Semantic Scholar
miR miR on the wall, who’s the most malignant medulloblastoma miR of them all?
X. Wang, B. Holgado, V. Ramaswamy, S. Mack +7 more
2017Neuro-Oncology19 citations Open access
Semantic Scholar
Sox9 directs divergent epigenomic states in brain tumor subtypes
Debosmita Sardar, Hsiao-Chi Chen, Amanda Reyes, S. Varadharajan +11 more
2022Proceedings of the National Academy of Sciences of the United States of America18 citations Open access
Semantic Scholar
Pediatric ependymoma: current treatment and newer therapeutic insights.
S. Khatua, Ross Mangum, K. Bertrand, W. Zaky +2 more
2018Future Oncology18 citations
Semantic Scholar
Targeting NAD+ biosynthesis overcomes panobinostat and bortezomib-induced malignant glioma resistance
Esther P. Jane, Daniel R. Premkumar, Swetha Thambireddy, B. Golbourn +9 more
2020Molecular Cancer Research15 citations Open access
Semantic Scholar
Why haven't we solved intracranial pediatric ependymoma? Current questions and barriers to treatment advances.
E. Hwang, D. Hanson, M. Filbin, S. Mack
2023Neoplasia12 citations Open access
Semantic Scholar
Maternal and perinatal factors are associated with risk of pediatric central nervous system tumors and poorer survival after diagnosis
Maral Adel Fahmideh, E. Peckham-Gregory, Jeremy M. Schraw, M. Chintagumpala +3 more
2021Scientific Reports8 citations Open access
Semantic Scholar
Durable Response to Larotrectinib in a Child With Histologic Diagnosis of Recurrent Disseminated Ependymoma Discovered to Harbor an NTRK2 Fusion: The Impact of Integrated Genomic Profiling.
Ross Mangum, J. Reuther, K. Bertrand, Raghu Chandramohan +15 more
2021JCO Precision Oncology8 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

J. Rich×17
Invite
J. Rich — researcher profile on SciRah
Qiulian Wu×16
Invite
Qiulian Wu — researcher profile on SciRah
Xiu-Xing Wang×16
Invite
Xiu-Xing Wang — researcher profile on SciRah
Michael D. Taylor×14
Invite
Michael D. Taylor — researcher profile on SciRah

×13

Invite

N. Jabado — researcher profile on SciRah

Invite

B. Prager — researcher profile on SciRah

Invite

R. Gimple — researcher profile on SciRah

V. Ramaswamy×11

Invite

V. Ramaswamy — researcher profile on SciRah

Invite

L. Garzia — researcher profile on SciRah

Invite

B. Luu — researcher profile on SciRah

Invite

P. Dirks — researcher profile on SciRah

Leo J. Y. Kim×9

Invite

Leo J. Y. Kim — researcher profile on SciRah