Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

A. Borkhardt · SciRah

Researcher profile · Semantic Scholar

A. Borkhardt

Share profile

A. Borkhardt — researcher profile on SciRah

h-index: 71
Works: 527
Citations: 27K

Most-cited papers

The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets
C. van Tilburg, E. Pfaff, K. Pajtler, K. Langenberg +70 more
2021Cancer Discovery206 citations Open access
Semantic Scholar
Induction of trained immunity by influenza vaccination - impact on COVID-19
P. Debisarun, Katharina L. Gössling, O. Bulut, Gizem Kılıç +20 more
2021medRxiv164 citations Open access
Semantic Scholar
Solid-Phase Synthesis of Cereblon-Recruiting Selective Histone Deacetylase 6 Degraders (HDAC6 PROTACs) with Antileukemic Activity.
Laura Sinatra, Jing Yang, Julian Schliehe-Diecks, N. Dienstbier +10 more
2022Journal of Medicinal Chemistry61 citations Open access
Semantic Scholar
Tacedinaline (CI-994), a class I HDAC inhibitor, targets intrinsic tumor growth and leptomeningeal dissemination in MYC-driven medulloblastoma while making them susceptible to anti-CD47-induced macrophage phagocytosis via NF-kB-TGM2 driven tumor inflammation
V. Marquardt, Johanna Theruvath, D. Pauck, D. Picard +34 more
2023Journal for ImmunoTherapy of Cancer55 citations Open access
Semantic Scholar
The long non-coding RNA HOTAIRM1 promotes tumor aggressiveness and radiotherapy resistance in glioblastoma
U. Ahmadov, D. Picard, J. Bartl, M. Silginer +33 more
2021Cell Death and Disease54 citations Open access
Semantic Scholar
Mutational mechanisms shaping the coding and noncoding genome of germinal center derived B-cell lymphomas
D. Hübschmann, K. Kleinheinz, R. Wagener, S. Bernhart +63 more
2021Leukemia54 citations Open access
Semantic Scholar
Toward prevention of childhood ALL by early-life immune training
J. Hauer, U. Fischer, A. Borkhardt
2021Blood51 citations Open access
Semantic Scholar
Clinical relevance of molecular characteristics in Burkitt lymphoma differs according to age
B. Burkhardt, U. Michgehl, Jonas Rohde, T. Erdmann +32 more
2022Nature Communications49 citations Open access
Semantic Scholar
Comprehensive germline-genomic and clinical profiling in 160 unselected children and adolescents with cancer
R. Wagener, Julia Taeubner, C. Walter, Layal Yasin +11 more
2021European Journal of Human Genetics48 citations Open access
Semantic Scholar
4-Acyl Pyrrole Capped HDAC Inhibitors: A New Scaffold for Hybrid Inhibitors of BET Proteins and Histone Deacetylases as Antileukemia Drug Leads.
L. Schäker-Hübner, Robin Warstat, H. Ahlert, Pankaj Mishra +9 more
2021Journal of Medicinal Chemistry42 citations Open access
Semantic Scholar
Hyperdiploidy: the longest known, most prevalent, and most enigmatic form of acute lymphoblastic leukemia in children
O. Haas, A. Borkhardt
2022Leukemia37 citations Open access
Semantic Scholar
The Microbiome in Childhood Acute Lymphoblastic Leukemia
M. Oldenburg, Nadine Rüchel, S. Janssen, A. Borkhardt +1 more
2021Cancers35 citations Open access
Semantic Scholar
The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors
J. Bartl, M. Zanini, Flavia Bernardi, Antoine Forget +44 more
2022Nature Communications30 citations Open access
Semantic Scholar
PAX5 fusion genes are frequent in poor risk childhood acute lymphoblastic leukaemia and can be targeted with BIBF1120
G. Fazio, S. Bresolin, D. Silvestri, M. Quadri +23 more
2022EBioMedicine27 citations Open access
Semantic Scholar
Development of fluorinated peptoid-based histone deacetylase (HDAC) inhibitors for therapy-resistant acute leukemia
Nina Reßing, Julian Schliehe-Diecks, P. Watson, Melf Sönnichsen +8 more
2022Journal of Medicinal Chemistry26 citations Open access
Semantic Scholar
An instructive role for Interleukin-7 receptor α in the development of human B-cell precursor leukemia
I. Geron, A. Savino, H. Fishman, N. Tal +26 more
2022Nature Communications25 citations Open access
Semantic Scholar
Temporal patterns of childhood cancer survival 1991 to 2016: A nationwide register‐study based on data from the German Childhood Cancer Registry
M. Wellbrock, C. Spix, C. Ronckers, D. Grabow +4 more
2023International Journal of Cancer22 citations Open access
Semantic Scholar
Consensus Recommendations for the Clinical Management of Hematological Malignancies in Patients with DNA Double Stranded Break Disorders
A. Pastorczak, A. Attarbaschi, S. Bomken, A. Borkhardt +10 more
2022Cancers22 citations Open access
Semantic Scholar
High-throughput screening as a drug repurposing strategy for poor outcome subgroups of pediatric B-cell precursor Acute Lymphoblastic Leukemia.
Athanasios Oikonomou, Luigia Valsecchi, M. Quadri, Titus Watrin +14 more
2023Biochemical Pharmacology21 citations Open access
Semantic Scholar
Pediatric Patients with Stage IV Rhabdomyosarcoma Significantly Benefit from Long-Term Maintenance Therapy: Results of the CWS-IV 2002 and the CWS DOK IV 2004-Trials
L. Tramsen, K. Bochennek, M. Sparber-Sauer, E. Salzmann-Manrique +14 more
2023Cancers20 citations Open access
Semantic Scholar
Circular RNA profiling distinguishes medulloblastoma groups and shows aberrant RMST overexpression in WNT medulloblastoma
Daniel Rickert, J. Bartl, D. Picard, Flavia Bernardi +13 more
2021Acta Neuropathologica20 citations Open access
Semantic Scholar
Haematological characteristics and spontaneous haematological recovery in Pearson syndrome
A. Yoshimi, S. Grünert, H. Cario, A. Fisch +16 more
2021British Journal of Haematology19 citations Open access
Semantic Scholar
BAFF Attenuates Immunosuppressive Monocytes in the Melanoma Tumor Microenvironment
Wei Liu, P. Stachura, Hai-Feng C. Xu, R. Váraljai +16 more
2021Cancer Research19 citations Open access
Semantic Scholar
Optical Genome Mapping Identifies Novel Recurrent Structural Alterations in Childhood ETV6::RUNX1+ and High Hyperdiploid Acute Lymphoblastic Leukemia
Danielle Brandes, Layal Yasin, K. Nebral, Jana Ebler +13 more
2023HemaSphere18 citations Open access
Semantic Scholar
C2orf69 mutations disrupt mitochondrial function and cause a multisystem human disorder with recurring autoinflammation.
E. Lausberg, Sebastian Giesselmann, J. Dewulf, Elsa Wiame +30 more
2021Journal of Clinical Investigation18 citations Open access
Semantic Scholar
Osteosarcoma and causes of death: A report of 1520 deceased patients from the Cooperative Osteosarcoma Study Group (COSS).
S. Bielack, C. Blattmann, A. Borkhardt, M. Csóka +17 more
2022European Journal of Cancer17 citations Open access
Semantic Scholar
Clinical and immunophenotypic characteristics of familial leukemia predisposition caused by PAX5 germline variants
A. Escudero, M. Takagi, F. Auer, U. Friedrich +11 more
2022Leukemia17 citations
Semantic Scholar
Deep Transfer Learning Approach for Automatic Recognition of Drug Toxicity and Inhibition of SARS-CoV-2
Julia Werner, R. Kronberg, P. Stachura, P. Ostermann +8 more
2021Viruses15 citations Open access
Semantic Scholar
Development of the first geldanamycin-based HSP90 degraders
Silas L. Wurnig, M. Vogt, J. Hogenkamp, N. Dienstbier +3 more
2023Frontiers in Chemistry14 citations Open access
Semantic Scholar
Arenaviruses: Old viruses present new solutions for cancer therapy
P. Stachura, Olivia Stencel, Zhe Lu, A. Borkhardt +1 more
2023Frontiers in Immunology14 citations Open access
Semantic Scholar
Temporal changes of the incidence of childhood cancer in Germany during the COVID-19 pandemic: Updated analyses from the German Childhood Cancer Registry
Friederike Erdmann, C. Spix, M. Schrappe, A. Borkhardt +1 more
2022The Lancet Regional Health - Europe14 citations Open access
Semantic Scholar
Accurate and scalable variant calling from single cell DNA sequencing data with ProSolo
David Lähnemann, J. Köster, U. Fischer, A. Borkhardt +2 more
2021Nature Communications14 citations Open access
Semantic Scholar
Definition and Prognostic Value of Ph-like and IKZF1plus Status in Children With Down Syndrome and B-cell Precursor Acute Lymphoblastic Leukemia
C. Palmi, S. Bresolin, S. Junk, G. Fazio +21 more
2023HemaSphere12 citations Open access
Semantic Scholar
Germline POT1 Deregulation Can Predispose to Myeloid Malignancies in Childhood
P. Michler, A. Schedel, Martha Witschas, U. Friedrich +15 more
2021International Journal of Molecular Sciences12 citations Open access
Semantic Scholar
A clinical screening tool to detect genetic cancer predisposition in pediatric oncology shows high sensitivity but can miss a substantial percentage of affected children.
U. Friedrich, M. Bienias, C. Zinke, M. Prazenicova +15 more
2023Genetics in Medicine11 citations Open access
Semantic Scholar
Functional damaging germline variants in ETV6, IKZF1, PAX5 and RUNX1 predisposing to B-cell precursor acute lymphoblastic leukemia.
R. Wagener, S. Elitzur, T. Brozou, A. Borkhardt
2023European Journal of Medical Genetics11 citations
Semantic Scholar
In Utero Development and Immunosurveillance of B Cell Acute Lymphoblastic Leukemia
Nadine Rüchel, V. Jepsen, D. Hein, U. Fischer +2 more
2022Current Treatment Options in Oncology11 citations Open access
Semantic Scholar
28-year incidence and time trends of childhood leukaemia in former East Germany compared to West Germany after German reunification: A study from the German Childhood Cancer Registry.
M. Wellbrock, C. Spix, D. Grabow, A. Borkhardt +2 more
2021Cancer Epidemiology11 citations
Semantic Scholar
The CHK2 kinase is recurrently mutated and functionally impaired in the germline of pediatric cancer patients
R. Wagener, C. Walter, F. Auer, Deya Alzoubi +6 more
2022International Journal of Cancer10 citations Open access
Semantic Scholar
Results from a pilot study on the oral microbiome in children and adolescents with chronic nonbacterial osteomyelitis
Mona Zeus, S. Janssen, H. Laws, U. Fischer +2 more
2021Zeitschrift für Rheumatologie (Print)10 citations Open access
Semantic Scholar
Unleashing T cell anti-tumor immunity: new potential for 5-Nonloxytryptamine as an agent mediating MHC-I upregulation in tumors
P. Stachura, W. Liu, Hai-Feng C. Xu, Agnès Wlodarczyk +12 more
2023Molecular Cancer9 citations Open access
Semantic Scholar
The Growing Spectrum of DADA2 Manifestations—Diagnostic and Therapeutic Challenges Revisited
Carolin S Escherich, B. Bötticher, S. Harmsen, Marc Hömberg +5 more
2022Frontiers in Pediatrics9 citations Open access
Semantic Scholar
Intratumoral heterogeneity of MYC drives medulloblastoma metastasis and angiogenesis.
N. Qin, E. Paisana, M. Langini, D. Picard +24 more
2022Neuro-Oncology9 citations Open access
Semantic Scholar
Single MHC‐I Expression Promotes Virus‐Induced Liver Immunopathology
Hai-Feng C. Xu, Jun Huang, A. Pandyra, Piyush Pandey +14 more
2022Hepatology Communications9 citations Open access
Semantic Scholar
Second-look surgery after pediatric brain tumor resection – Single center analysis of morbidity and volumetric efficacy
A. K. Schmitz, C. Munoz-Bendix, M. Remke, T. Brozou +3 more
2022Brain and Spine9 citations Open access
Semantic Scholar
Increasing incidence and survival of paediatric and adolescent thyroid cancer in Cyprus 1998-2017: A population-based study from the Cyprus Pediatric Oncology Registry.
L. Loizou, A. Demetriou, Friederike Erdman, A. Borkhardt +3 more
2021Cancer Epidemiology9 citations Open access
Semantic Scholar
Chemotherapy-related hyperbilirubinemia in pediatric acute lymphoblastic leukemia: a genome-wide association study from the AIEOP-BFM ALL study group
S. Junk, E. Schaeffeler, M. Zimmermann, A. Möricke +21 more
2023Journal of experimental & clinical cancer research : CR8 citations Open access
Semantic Scholar
Synthesis, Antiplasmodial, and Antileukemia Activity of Dihydroartemisinin–HDAC Inhibitor Hybrids as Multitarget Drugs
Lukas von Bredow, T. M. Schäfer, J. Hogenkamp, Maik Tretbar +8 more
2022Pharmaceuticals8 citations Open access
Semantic Scholar
The impact of the COVID‐19 pandemic on the future incidence of acute lymphoblastic leukaemia in children: Projections for Germany under a COVID‐19 related scenario
J. Schüz, A. Borkhardt, L. Bouaoun, Friederike Erdmann
2022International Journal of Cancer8 citations Open access
Semantic Scholar
Oxa Analogues of Nexturastat A Demonstrate Improved HDAC6 Selectivity and Superior Antileukaemia Activity
Marc Pflieger, Melf Sönnichsen, Nadine Horstick-Muche, Jing Yang +8 more
2021ChemMedChem8 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

U. Fischer×13
Invite
U. Fischer — researcher profile on SciRah
S. Bhatia×11
Invite
S. Bhatia — researcher profile on SciRah
D. Picard×8
Invite
D. Picard — researcher profile on SciRah
M. Remke×8
Invite
M. Remke — researcher profile on SciRah

×8

Invite

T. Brozou — researcher profile on SciRah

Invite

F. Hansen — researcher profile on SciRah

Invite

J. Hauer — researcher profile on SciRah

Invite

R. Wagener — researcher profile on SciRah

Julian Schliehe-Diecks×5

Invite

Julian Schliehe-Diecks — researcher profile on SciRah

Invite

K. Stühler — researcher profile on SciRah

Andrea Schöler×5

Invite

Andrea Schöler — researcher profile on SciRah

Invite

N. Qin — researcher profile on SciRah