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K. Kerl · SciRah

Researcher profile · Semantic Scholar

K. Kerl

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K. Kerl — researcher profile on SciRah

h-index: 27
Works: 129
Citations: 3,098

Most-cited papers

Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes.
P. Johann, S. Erkek, M. Zapatka, K. Kerl +54 more
2016Cancer Cell504 citations Open access
Semantic Scholar
Childhood cancer predisposition syndromes—A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology
T. Ripperger, S. Bielack, A. Borkhardt, I. Brecht +72 more
2017American Journal of Medical Genetics. Part A247 citations Open access
Semantic Scholar
The BAF complex in development and disease
Amelie Alfert, N. Moreno, K. Kerl
2019Epigenetics & Chromatin221 citations Open access
Semantic Scholar
Infant high grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes
M. Clarke, A. Mackay, B. Ismer, Jessica C. Pickles +110 more
2020Cancer Discovery215 citations Open access
Semantic Scholar
Age and DNA-methylation subgroup as potential independent risk factors for treatment stratification in children with Atypical Teratoid/Rhabdoid Tumors (ATRT).
M. Frühwald, M. Hasselblatt, K. Nemes, S. Bens +37 more
2019Neuro-Oncology116 citations Open access
Semantic Scholar
EZH2 Inhibition in Ewing Sarcoma Upregulates GD2 Expression for Targeting with Gene-Modified T Cells.
S. Kailayangiri, B. Altvater, S. Lesch, S. Balbach +16 more
2019Molecular Therapy103 citations Open access
Semantic Scholar
Identification and Analyses of Extra-Cranial and Cranial Rhabdoid Tumor Molecular Subgroups Reveal Tumors with Cytotoxic T Cell Infiltration
Hye-Jung E. Chun, P. Johann, K. Milne, M. Zapatka +28 more
2019Cell Reports97 citations Open access
Semantic Scholar
Improved 6‐year overall survival in AT/RT – results of the registry study Rhabdoid 2007
K. Bartelheim, K. Nemes, A. Seeringer, K. Kerl +20 more
2016Cancer Medicine85 citations Open access
Semantic Scholar
Current status and future prospects of nanomedicine for arsenic trioxide delivery to solid tumors
Marthe Sönksen, K. Kerl, Hana Bunzen
2021Medicinal research reviews (Print)53 citations Open access
Semantic Scholar
Zeolitic Imidazolate Framework‐8 as pH‐Sensitive Nanocarrier for “Arsenic Trioxide” Drug Delivery
Romy L. Ettlinger, N. Moreno, D. Volkmer, K. Kerl +1 more
2019Chemistry53 citations Open access
Semantic Scholar
BRD9 Inhibition, Alone or in Combination with Cytostatic Compounds as a Therapeutic Approach in Rhabdoid Tumors
Katja Krämer, N. Moreno, M. Frühwald, K. Kerl
2017International Journal of Molecular Sciences53 citations Open access
Semantic Scholar
Intratumor heterogeneity and T cell exhaustion in primary CNS lymphoma
Michael O. Heming, Svea Haessner, Jolien Wolbert, I-Na Lu +15 more
2022Genome Medicine52 citations Open access
Semantic Scholar
Current recommendations for clinical surveillance and genetic testing in rhabdoid tumor predisposition: a report from the SIOPE Host Genome Working Group
M. Frühwald, K. Nemes, H. Boztug, M. Cornips +15 more
2021Familial Cancer43 citations Open access
Semantic Scholar
MAPK inhibitor sensitivity scores predict sensitivity driven by the immune infiltration in pediatric low-grade gliomas
R. Sigaud, T. Albert, C. Hess, T. Hielscher +32 more
2023Nature Communications36 citations Open access
Semantic Scholar
Metal-organic framework nanoparticles for arsenic trioxide drug delivery.
Romy L. Ettlinger, Marthe Sönksen, M. Graf, N. Moreno +4 more
2018Journal of materials chemistry. B34 citations Open access
Semantic Scholar
Divergent WNT signaling and drug sensitivity profiles within hepatoblastoma tumors and organoids
T. Kluiver, Yuyan Lu, Stephanie A. Schubert, Lianne Kraaier +21 more
2024Nature Communications30 citations Open access
Semantic Scholar
Infants and Newborns with Atypical Teratoid Rhabdoid Tumors (ATRT) and Extracranial Malignant Rhabdoid Tumors (eMRT) in the EU-RHAB Registry: A Unique and Challenging Population
K. Nemes, P. Johann, Mona Steinbügl, Miriam Gruhle +33 more
2022Cancers30 citations Open access
Semantic Scholar
Atypical teratoid/rhabdoid tumoroids reveal subgroup-specific drug vulnerabilities
Irene Paassen, Justin S. Williams, Carla Ríos Arceo, Femke C. A. Ringnalda +14 more
2023Oncogene28 citations Open access
Semantic Scholar
Macrophage-tumor cell interaction promotes ATRT progression and chemoresistance
V. Melcher, M. Graf, M. Interlandi, N. Moreno +14 more
2019Acta Neuropathologica28 citations
Semantic Scholar
Clinical and genetic risk factors define two risk groups of extracranial malignant rhabdoid tumours (eMRT/RTK).
K. Nemes, S. Bens, D. Kachanov, M. Teleshova +30 more
2020European Journal of Cancer27 citations Open access
Semantic Scholar
Combined BRD4 and CDK9 inhibition as a new therapeutic approach in malignant rhabdoid tumors.
N. Moreno, T. Holsten, J. Mertins, Annabelle Zhogbi +4 more
2017OncoTarget27 citations Open access
Semantic Scholar
Single-cell transcriptomics identifies potential cells of origin of MYC rhabdoid tumors
M. Graf, M. Interlandi, N. Moreno, D. Holdhof +20 more
2022Nature Communications25 citations Open access
Semantic Scholar
In Vitro Studies of Fe3O4‐ZIF‐8 Core–Shell Nanoparticles Designed as Potential Theragnostics
Romy L. Ettlinger, N. Moreno, N. Ziółkowska, A. Ullrich +4 more
2020Particle & particle systems characterization22 citations Open access
Semantic Scholar
InterCellar enables interactive analysis and exploration of cell−cell communication in single-cell transcriptomic data
M. Interlandi, K. Kerl, M. Dugas
2022Communications Biology21 citations Open access
Semantic Scholar
Toxoplasmosis after allogeneic haematopoietic cell transplantation (HCT) - Disease burden and approaches to diagnosis, prevention, and management in adults and children.
Kerstin K Rauwolf, Matthias Floeth, K. Kerl, F. Schaumburg +1 more
2020Clinical Microbiology and Infection20 citations Open access
Semantic Scholar
Biological material collection to advance translational research and treatment of children with CNS tumours: position paper from the SIOPE Brain Tumour Group.
S. Rutkowski, P. Modena, D. Williamson, K. Kerl +29 more
2018The Lancet Oncology18 citations Open access
Semantic Scholar
Multiomic analysis uncovers a continuous spectrum of differentiation and Wnt-MDK-driven immune evasion in hepatoblastoma.
Daniel Münter, F. D. de Faria, M. Richter, Irene Aranda-Pardos +27 more
2025Journal of Hepatology16 citations Open access
Semantic Scholar
Mouse models of pediatric high-grade gliomas with MYCN amplification reveal intratumoral heterogeneity and lineage signatures
M. Schoof, Shweta Godbole, T. Albert, M. Dottermusch +28 more
2023Nature Communications16 citations Open access
Semantic Scholar
Combined BRD4 and CDK9 inhibition as a new therapeutic approach in malignant rhabdoid tumors
N. Moreno, T. Holsten, J. Mertins, Annabelle Zhogbi +4 more
2017OncoTarget14 citations Open access
Semantic Scholar
Brahma-related gene 1 has time-specific roles during brain and eye development.
D. Holdhof, M. Schoof, S. Al-Kershi, M. Spohn +7 more
2021Development13 citations
Semantic Scholar
An extracellular vesicle-related gene expression signature identifies high-risk patients in medulloblastoma.
T. Albert, M. Interlandi, M. Sill, M. Graf +18 more
2020Neuro-Oncology13 citations Open access
Semantic Scholar
The CXCL16/CXCR6 axis is linked to immune effector cell-associated neurotoxicity in chimeric antigen receptor (CAR) T cell therapy
I-Na Lu, L. Müller-Miny, Carolin Krekeler, Phyllis Fung-Yi Cheung +12 more
2025Genome Medicine12 citations Open access
Semantic Scholar
MSH2, MSH6, MLH1, and PMS2 immunohistochemistry as highly sensitive screening method for DNA mismatch repair deficiency syndromes in pediatric high-grade glioma
L. Friker, T. Perwein, Andreas Waha, Evelyn Dörner +34 more
2025Acta Neuropathologica12 citations Open access
Semantic Scholar
Clinical evidence for a biological effect of epigenetically active decitabine in relapsed or progressive rhabdoid tumors
Mona Steinbügl, K. Nemes, P. Johann, T. Kröncke +16 more
2021Pediatric Blood & Cancer12 citations Open access
Semantic Scholar
Three-Dimensional Cell Culture Systems in Pediatric and Adult Brain Tumor Precision Medicine
Nicole C. Riedel, F. D. de Faria, Amelie Alfert, J. Bruder +1 more
2022Cancers11 citations Open access
Semantic Scholar
The Growing Relevance of Immunoregulation in Pediatric Brain Tumors
V. Melcher, K. Kerl
2021Cancers11 citations Open access
Semantic Scholar
Clinically relevant molecular hallmarks of PFA ependymomas display intratumoral heterogeneity and correlate with tumor morphology
Swenja Gödicke, C. Kresbach, M. Ehlert, D. Obrecht +13 more
2024Acta Neuropathologica8 citations Open access
Semantic Scholar
Lack of SMARCB1 expression characterizes a subset of human and murine peripheral T-cell lymphomas
A. Fischer, T. Albert, N. Moreno, M. Interlandi +51 more
2024Nature Communications8 citations Open access
Semantic Scholar
Single-cell transcriptomics link gene expression signatures to clinicopathological features of gonadotroph and lactotroph PitNET
T. E. Potthoff, C. Walter, Daniela Jeising, Daniel Münter +12 more
2024Journal of Translational Medicine8 citations Open access
Semantic Scholar
The tumor suppressor CREBBP and the oncogene MYCN cooperate to induce malignant brain tumors in mice
M. Schoof, Gefion Dorothea Epplen, C. Walter, Annika Ballast +7 more
2023Oncogenesis8 citations Open access
Semantic Scholar
Group-specific cellular metabolism in Medulloblastoma
Viktoria L. E. Funke, C. Walter, V. Melcher, Lan-Ying Wei +17 more
2023Journal of Translational Medicine7 citations Open access
Semantic Scholar
Toxicity Reduction after Craniospinal Irradiation via Helical Tomotherapy in Patients with Medulloblastoma: A Unicentric Retrospective Analysis
Anil Öztunali, K. Elsayad, S. Scobioala, Mohammed Channaoui +7 more
2021Cancers7 citations Open access
Semantic Scholar
A Carboxy-terminal Smarcb1 Point Mutation Induces Hydrocephalus Formation and Affects AP-1 and Neuronal Signalling Pathways in Mice
Aliska K Brugmans, C. Walter, N. Moreno, Carolin Göbel +14 more
2023Cellular and molecular neurobiology6 citations Open access
Semantic Scholar
ETMR stem-like state and chemo-resistance are supported by perivascular cells at single-cell resolution
F. D. de Faria, Nicole C. Riedel, Daniel Münter, M. Interlandi +35 more
2025Nature Communications5 citations Open access
Semantic Scholar
Smarcb1 Loss Results in a Deregulation of esBAF Binding and Impacts the Expression of Neurodevelopmental Genes
Amelie Alfert, C. Walter, N. Moreno, V. Melcher +5 more
2022Cells5 citations Open access
Semantic Scholar
Investigation of a global mouse methylome atlas reveals subtype-specific copy number alterations in pediatric cancer models
M. Schoof, T. Zheng, M. Sill, R. Imle +50 more
2025Nature Genetics4 citations Open access
Semantic Scholar
Multi-dimensional profiling of hepatoblastomas and patient-derived tumor organoids uncovers tumor subpopulations with divergent WNT activation profiles and identifies pan-hepatoblastoma drug sensitivities
T. Kluiver, Yuyan Lu, Stephanie A. Schubert, Lianne Kraaier +21 more
2023bioRxiv4 citations Open access
Semantic Scholar
Mitochondrial DNA mutations in Medulloblastoma
Viktoria L. E. Funke, S. Sandmann, V. Melcher, Jochen Seggewiss +17 more
2023Acta Neuropathologica Communications4 citations Open access
Semantic Scholar
ATRT-09. Outcome and therapeutic interventions in relapsed and refractory ATRT – The EU-RHAB perspective
Mona Steinbügl, K. Nemes, Miriam Gruhle, P. Johann +17 more
2022Neuro-Oncology4 citations Open access
Semantic Scholar
Primary cilia contribute to the aggressiveness of atypical teratoid/rhabdoid tumors
Lena Blümel, N. Qin, J. Berlandi, E. Paisana +25 more
2022Cell Death and Disease4 citations Open access
Semantic Scholar

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