Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

D. Welsch · SciRah

Researcher profile · Semantic Scholar

D. Welsch

Share profile

D. Welsch — researcher profile on SciRah

h-index: 21
Works: 49
Citations: 2,518

Most-cited papers

Eradication of Tumors through Simultaneous Ablation of CD276/B7-H3 Positive Tumor Cells and Tumor Vasculature
S. Seaman, Zhong-Yu Zhu, S. Saha, Xiaoyan M Zhang +23 more
2017Cancer Cell374 citations Open access
Semantic Scholar
First-in-Class ERK1/2 Inhibitor Ulixertinib (BVD-523) in Patients with MAPK Mutant Advanced Solid Tumors: Results of a Phase I Dose-Escalation and Expansion Study.
R. Sullivan, J. Infante, F. Janku, D. Wong +23 more
2017Cancer Discovery359 citations Open access
Semantic Scholar
Real-time genomic characterization of advanced pancreatic cancer to enable precision medicine
Andrew J. Aguirre, J. Nowak, Nicholas D. Camarda, R. Moffitt +57 more
2018Cancer Discovery306 citations Open access
Semantic Scholar
Metalloproteases and inhibitors in arthritic diseases.
J. Martel-Pelletier, D. Welsch, J. Pelletier
2001Baillière's Best Practice & Research : Clinical Rheumatology283 citations
Semantic Scholar
Targeting the MAPK Signaling Pathway in Cancer: Promising Preclinical Activity with the Novel Selective ERK1/2 Inhibitor BVD-523 (Ulixertinib)
U. Germann, Brinley F Furey, W. Markland, R. R. Hoover +17 more
2017Molecular Cancer Therapeutics204 citations Open access
Semantic Scholar
Tumor stroma‐targeted antibody‐drug conjugate triggers localized anticancer drug release
C. Szot, S. Saha, Xiaoyan M Zhang, Zhong-Yu Zhu +18 more
2018Journal of Clinical Investigation105 citations Open access
Semantic Scholar
The ligand-dependent interaction of mineralocorticoid receptor with coactivator and corepressor peptides suggests multiple activation mechanisms.
Monica L Hultman, N. V. Krasnoperova, Suzhen Li, Sarah Du +5 more
2005Molecular Endocrinology99 citations Open access
Semantic Scholar
Orally active MMP-1 sparing α-tetrahydropyranyl and α-piperidinyl sulfone matrix metalloproteinase (MMP) inhibitors with efficacy in cancer, arthritis, and cardiovascular disease.
D. Becker, T. Barta, L. Bedell, T. Boehm +23 more
2010Journal of Medicinal Chemistry92 citations Open access
Semantic Scholar
Solution structure and backbone dynamics of the catalytic domain of matrix metalloproteinase-2 complexed with a hydroxamic acid inhibitor.
Yiqing Feng, J. Likos, Leiming Zhu, H. Woodward +8 more
2002Biochimica et Biophysica Acta91 citations
Semantic Scholar
Discovery and development of a type II collagen neoepitope (TIINE) biomarker for matrix metalloproteinase activity: from in vitro to in vivo.
O. Nemirovskiy, D. Dufield, T. Sunyer, P. Aggarwal +2 more
2007Analytical Biochemistry84 citations
Semantic Scholar
Novel, selective delta6 or delta5 fatty acid desaturase inhibitors as antiinflammatory agents in mice.
M. Obukowicz, D. Welsch, W. Salsgiver, C. Martin-Berger +4 more
1999Lipids65 citations
Semantic Scholar
Expression and characterization of human factor IX and factor IX-factor X chimeras in mouse C127 cells.
Shu-Wha Lin, K. J. Smith, D. Welsch, D. W. Stafford
1990Journal of Biological Chemistry52 citations Open access
Semantic Scholar
First-in-human study of IM156, a novel potent biguanide oxidative phosphorylation (OXPHOS) inhibitor, in patients with advanced solid tumors
F. Janku, S. Beom, Y. Moon, Tae Won Kim +13 more
2022Investigational new drugs46 citations Open access
Semantic Scholar
Partial purification and characterization of bovine liver aspartyl beta-hydroxylase.
R. S. Gronke, D. Welsch, W. Vandusen, Victor M. Garsky +3 more
1990Journal of Biological Chemistry44 citations Open access
Semantic Scholar
Association between concentrations of urinary type II collagen neoepitope (uTIINE) and joint space narrowing in patients with knee osteoarthritis.
M. L. le Graverand, K. Brandt, S. Mazzuca, B. P. Katz +6 more
2006Osteoarthritis and Cartilage37 citations Open access
Semantic Scholar
The CTSA Pharmaceutical Assets Portal – a public–private partnership model for drug repositioning
K. Marusina, D. Welsch, Lynn M. Rose, Doug Brock +1 more
2011Drug Discovery Today : Therapeutic Strategies30 citations Open access
Semantic Scholar
Effect of ulixertinib, a novel ERK1/2 inhibitor, on the QT/QTc interval in patients with advanced solid tumor malignancies
B. Mendzelevski, G. Ferber, F. Janku, Bob T. Li +6 more
2018Cancer Chemotherapy and Pharmacology27 citations Open access
Semantic Scholar
Characterization and Management of ERK Inhibitor Associated Dermatologic Adverse Events: Analysis from a Nonrandomized Trial of Ulixertinib for Advanced Cancers
J. Wu, D. Liu, M. Offin, C. Lezcano +14 more
2021Investigational new drugs25 citations Open access
Semantic Scholar
Comparison of Recombinant Tissue Factor Pathway Inhibitors Expressed in Human SK Hepatoma, Mouse C127, Baby Hamster Kidney, and Chinese Hamster Ovary Cells
T. Wun, K. Kretzmer, M. Palmier, K. Day +20 more
1992Thrombosis and Haemostasis25 citations
Semantic Scholar
Discovery of a novel series of selective MMP inhibitors: Identification of the γ-sulfone-thiols
John N. Freskos, Mischke Brent, G. Decrescenzo, M. HeintzRobert +9 more
199924 citations Open access
Semantic Scholar
Discovery of an Oral Potent Selective Inhibitor of Hematopoietic Prostaglandin D Synthase (HPGDS).
C. Carron, John I. Trujillo, Kirk L. Olson, Wei Huang +31 more
2010ACS Medicinal Chemistry Letters22 citations Open access
Semantic Scholar
Abstract 4693: The selective ERK inhibitor BVD-523 is active in models of MAPK pathway-dependent cancers, including those with intrinsic and acquired drug resistance
U. Germann, Brinley F Furey, J. Roix, W. Markland +17 more
201521 citations
Semantic Scholar
Modulation of Oxidative Phosphorylation with IM156 Attenuates Mitochondrial Metabolic Reprogramming and Inhibits Pulmonary Fibrosis
R. Willette, P. Mangrolia, Stephen M Pondell, C. Lee +4 more
2021Journal of Pharmacology and Experimental Therapeutics17 citations Open access
Semantic Scholar
Dose escalation stage of a first-in-class phase I study of the novel oral ERK 1/2 kinase inhibitor BVD-523 (ulixertinib) in patients with advanced solid tumors.
J. Infante, F. Janku, A. Tolcher, M. Patel +13 more
201517 citations
Semantic Scholar
Renaturation and purification of human tissue factor pathway inhibitor expressed in recombinant E. coli.
M. E. Gustafson, K. D. Junger, Tze-Chein Wun, B. Foy +12 more
1994Protein Expression and Purification17 citations
Semantic Scholar
Lipid remodeling in mouse liver and plasma resulting from Δ6 fatty acid desaturase inhibition
K. Duffin, M. Obukowicz, W. Salsgiver, D. Welsch +3 more
2001Lipids13 citations
Semantic Scholar
First-in-class oral ERK1/2 inhibitor Ulixertinib (BVD-523) in patients with advanced solid tumors: Final results of a phase I dose escalation and expansion study.
Bob T. Li, F. Janku, M. Patel, R. Sullivan +16 more
201712 citations
Semantic Scholar
Letter to the Editor: 1H, 13C and 15N resonance assignments for a truncated and inhibited catalytic domain of matrix metalloproteinase-2
Yiqing Feng, J. Likos, Leiming Zhu, H. Woodward +4 more
20008 citations
Semantic Scholar
Novel, selective delta6 or delta5 fatty acid desaturase inhibitors as antiinflammatory agents in mice.
M. Obukowicz, D. Welsch, W. Salsgiver, C. Martin-Berger +4 more
1998Journal of Pharmacology and Experimental Therapeutics7 citations
Semantic Scholar
Modulation of adjuvant-induced arthritis by dietary arachidonic acid in essential fatty acid-deficient rats
K. Chinn, D. Welsch, W. Salsgiver, Aniali Mehta +2 more
1997Lipids5 citations
Semantic Scholar
Discovery of a novel series of selective MMP inhibitors: identification of the gamma-sulfone-thiols.
J. Freskos, B. Mischke, G. Decrescenzo, R. Heintz +9 more
1999Bioorganic & Medicinal Chemistry Letters3 citations
Semantic Scholar
A phase 1b dose escalation trial of gemcitabine and nab-paclitaxel in combination with lixumistat in patients with advanced pancreatic cancer.
Shubham Pant, B. Smaglo, R. Huey, S. Haldar +15 more
2025Journal of Clinical Oncology2 citations Open access
Semantic Scholar
Serum Matrix Metalloproteinase Levels and Activities in Patients With Glaucoma
J. Yang, K. Zhang, C. Howard, D. Knoerzer +3 more
20032 citations
Semantic Scholar
Therapeutic efficacy of Sunitinib and other broad spectrum receptor tyrosine kinase inhibitors (RTKI) in bleomycin-induced pulmonary fibrosis
D. Knoerzer, T. Baginski, K. Wade, C. Fan +6 more
2013Journal of Inflammation1 citations Open access
Semantic Scholar
Inhibition Of Activated Thrombin Activatable Fibrinolysis Inhibitor (TAFI) Demonstrates Therapeutic Efficacy In Bleomycin-Induced Pulmonary Fibrosis In Mice
D. Knoerzer, T. Baginski, K. Wade, C. Fan +7 more
2010Asian Test Symposium1 citations
Semantic Scholar
Erratum to “Discovery and development of a type II collagen neoepitope (TIINE) biomarker for matrix metalloproteinase activity: From in vitro to in vivo” [Anal. Biochem. 361 (2007) 93–113]
O. Nemirovskiy, D. Dufield, T. Sunyer, P. Aggarwal +2 more
20071 citations
Semantic Scholar
831 Targeting tumor oxidative metabolism to overcome hypoxia-induced immunotherapy resistance in prostate cancer
P. Jayaprakash, Michael Curran, Brittany Morrow, J. Marszalek +6 more
2022Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
DISRUPTED OXYGEN SUPPLY AND TUMOR HYPER-OXYGEN CONSUMPTION CONTRIBUTE INDEPENDENTLY TO PROSTATE CANCER IMMUNE PRIVILEGE
P. Jayaprakash, Meghan A. Rice, Krithikaa Rajkumar Bhanu, Brittany Morrow +6 more
20210 citations
Semantic Scholar
622 Disrupted oxygen supply and tumor hyper- oxygen consumption contribute independently to prostate cancer immune privilege
P. Jayaprakash, Meghan A. Rice, Krithikaa Rajkumar Bhanu, Brittany Morrow +6 more
2021Journal for ImmunoTherapy of Cancer0 citations Open access
Semantic Scholar
Abstract B085: Preclinical pharmacokinetic/pharmacodynamic (PK/PD) relationship demonstrated for BVD-723, a potent and selective phosphoinositide 3-kinase gamma (PI3Kγ) inhibitor
D. Knoerzer, M. Teresk, Peter O. Krutzik, E. O'Donnell +3 more
20180 citations
Semantic Scholar
Abstract CT003: Activity of the ERK1/2 inhibitor ulixertinib (BVD-523) in patients withBRAFandNRASmutant melanoma
R. Sullivan, F. Janku, Bob T. Li, D. Wong +16 more
20170 citations
Semantic Scholar
Anticorps anti-cd276 (b7h3)
D. Dimitrov, Zhong-Yu Zhu, B. St Croix, S. Seaman +4 more
20150 citations
Semantic Scholar
Evaluation of 1-(2-deoxy-2-fluoro-1-d-arabinofuranosyl)-5-iodouracil (FIAU) as an ex vivo bacterial detection agent
David Tung, G. Decrescenzo, D. Welsch, Peter H. Cheung +2 more
2014World Journal of Microbiology & Biotechnology0 citations
Semantic Scholar
Partnerships for Drug Repositioning: Lessons from the CTSA Pharmaceutical Assets Portal
K. Marusina, D. Welsch, Lynn M. Rose, Doug Brock +8 more
20140 citations
Semantic Scholar
Therapeutic Efficacy Of Sutent® And Other Broad Spectrum Receptor Tyrosine Kinase Inhibitors (RTKi) In Bleomycin-Induced Pulmonary Fibrosis In Mice
D. Knoerzer, T. Baginski, K. Wade, C. Fan +6 more
2010Asian Test Symposium0 citations
Semantic Scholar
Therapeutic Efficacy Of Sutent® In A Preclinical Model Of Pulmonary Arterial Hypertension (PAH)
S. Rapp, H. Meade, D. Knoerzer, K. Shevlin +6 more
2010Asian Test Symposium0 citations
Semantic Scholar
SOLUTION STRUCTURE OF A CATALYTIC DOMAIN OF MMP-2 COMPLEXED WITH SC-74020
Y. Feng, J. Likos, L. Zhu, H. Woodward +8 more
20010 citations
Semantic Scholar
1H, 13C and 15N resonance assignments for a truncated and inhibited catalytic domain of matrix metalloproteinase-2.
Y. Feng, J. Likos, L. Zhu, H. Woodward +4 more
2000Journal of Biomolecular NMR0 citations
Semantic Scholar
Anti-CD 276-drug conjugates display potent anti-tumor and anti-metastatic activity d Pyrrolobenzodiazepine dimers are optimal warheads for targeting tumor
S. Seaman, Zhong-Yu Zhu, S. Saha, Xiaoyan M Zhang +23 more
0 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

G. Decrescenzo×12
Invite
G. Decrescenzo — researcher profile on SciRah
S. Saha×9
Invite
S. Saha — researcher profile on SciRah
F. Janku×7
Invite
F. Janku — researcher profile on SciRah
D. Knoerzer×7
Invite
D. Knoerzer — researcher profile on SciRah

×7

Invite

J. Mcdonald — researcher profile on SciRah

Invite

R. Sullivan — researcher profile on SciRah

Invite

S. Seaman — researcher profile on SciRah

Zhong-Yu Zhu×4

Invite

Zhong-Yu Zhu — researcher profile on SciRah

Xiaoyan M Zhang×4

Invite

Xiaoyan M Zhang — researcher profile on SciRah

Invite

D. Dimitrov — researcher profile on SciRah

Invite

B. St Croix — researcher profile on SciRah

Invite

J. Infante — researcher profile on SciRah