Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

K. Atwal · SciRah

Researcher profile · Semantic Scholar

K. Atwal

Share profile

K. Atwal — researcher profile on SciRah

h-index: 24
Works: 80
Citations: 2,182

Most-cited papers

Substituted 1,4-dihydropyrimidines. 3. Synthesis of selectively functionalized 2-hetero-1,4-dihydropyrimidines
K. Atwal, G. Rovnyak, B. O'Reilly, J. Schwartz
1989337 citations
Semantic Scholar
Dihydropyrimidine calcium channel blockers: 2-heterosubstituted 4-aryl-1,4-dihydro-6-methyl-5-pyrimidinecarboxylic acid esters as potent mimics of dihydropyridines.
K. Atwal, G. Rovnyak, Joseph Schwartz, Suzanne Moreland +4 more
1990Journal of Medicinal Chemistry164 citations Open access
Semantic Scholar
Excessive ATP hydrolysis in ischemic myocardium by mitochondrial F1F0-ATPase: effect of selective pharmacological inhibition of mitochondrial ATPase hydrolase activity.
G. Grover, K. Atwal, P. Sleph, Feng-Li Wang +3 more
2004American Journal of Physiology. Heart and Circulatory Physiology127 citations
Semantic Scholar
Pharmacologic characterization of BMS-191095, a mitochondrial K(ATP) opener with no peripheral vasodilator or cardiac action potential shortening activity.
G. Grover, A. D'Alonzo, K. Garlid, R. Bajgar +7 more
2001Journal of Pharmacology and Experimental Therapeutics99 citations
Semantic Scholar
Cardioselective anti-ischemic ATP-sensitive potassium channel openers.
K. Atwal, G. Grover, S. Z. Ahmed, F. N. Ferrara +6 more
1993Journal of Medicinal Chemistry92 citations
Semantic Scholar
Cardioprotective effects of the potassium channel opener cromakalim: stereoselectivity and effects on myocardial adenine nucleotides.
G. Grover, J. Newburger, P. Sleph, S. Dzwonczyk +3 more
1991Journal of Pharmacology and Experimental Therapeutics90 citations
Semantic Scholar
Pyrrolidine amides of pyrazolodihydropyrimidines as potent and selective KV1.5 blockers.
J. Lloyd, Heather J. Finlay, Wayne Vacarro, Tram Hyunh +11 more
2010Bioorganic & Medicinal Chemistry Letters77 citations Open access
Semantic Scholar
Triphenylphosphine Oxide Is a Potent and Selective Inhibitor of the Transient Receptor Potential Melastatin-5 Ion Channel
R. K. Palmer, K. Atwal, Ivona Bakaj, Stacy Carlucci-Derbyshire +10 more
2010Assay and drug development technologies72 citations
Semantic Scholar
Cardioprotective Profile of the Cardiac‐Selective ATP‐Sensitive Potassium Channel Opener BMS‐180448
G. Grover, J. Mccullough, A. D'Alonzo, C. Sargent +1 more
1995Journal of Cardiovascular Pharmacology68 citations Open access
Semantic Scholar
Dihydropyrimidine calcium channel blockers 51: bicyclic dihydropyrimidines as potent mimics of dihydropyridines
K. Atwal, S. Moreland
199166 citations
Semantic Scholar
Synthesis and biological activity of novel calcium channel blockers: 2,5-dihydro-4-methyl-2-phenyl-1,5-benzothiazepine-3-carboxylic acid esters and 2,5-dihydro-4-methyl-2-phenyl-1,5-benzodiazepine-3-carboxylic acid esters.
K. Atwal, J. L. Bergey, A. Hedberg, Suzanne Moreland
1987Journal of Medicinal Chemistry65 citations Open access
Semantic Scholar
Tryptamine and homotryptamine-based sulfonamides as potent and selective inhibitors of 15-lipoxygenase.
D. S. Weinstein, Wen Liu, Zheng-Xiang Gu, C. Langevine +14 more
2005Bioorganic & Medicinal Chemistry Letters54 citations Open access
Semantic Scholar
A facile synthesis of cyanoguanidines from thioureas
K. Atwal, S. T. Ahmed, B. O'Reilly
198949 citations
Semantic Scholar
Modulation of potassium channels by organic molecules
K. Atwal
1992Medicinal research reviews (Print)44 citations
Semantic Scholar
Synthesis of benzazepinone and 3-methylbenzothiazepinone analogs of diltiazem
D. Floyd, R. Moquin, K. Atwal, Sayed Ahmed +3 more
199040 citations
Semantic Scholar
Synthesis and biological activity of 5-aryl-4-(4-(5-methyl-1H-imidazol-4-yl)piperidin-1-yl)pyrimidine analogs as potent, highly selective, and orally bioavailable NHE-1 inhibitors.
K. Atwal, S. O'Neil, Saleem Ahmad, L. Doweyko +6 more
2006Bioorganic & Medicinal Chemistry Letters39 citations Open access
Semantic Scholar
Dihydropyrazolopyrimidines containing benzimidazoles as K(V)1.5 potassium channel antagonists.
J. Lloyd, Heather J. Finlay, K. Atwal, A. Kover +11 more
2009Bioorganic & Medicinal Chemistry Letters36 citations Open access
Semantic Scholar
Cardioselective antiischemic ATP-sensitive potassium channel openers. 2. Structure-activity studies on benzopyranylcyanoguanidines: modification of the benzopyran ring.
K. Atwal, Gary J. Grover, F. N. Ferrara, S. T. Ahmed +3 more
1995Journal of Medicinal Chemistry35 citations
Semantic Scholar
Pharmacology and Structure‐Activity Relationships for KATP Modulators: Tissue‐Selective KATP Openers
K. Atwal
1994Journal of Cardiovascular Pharmacology34 citations Open access
Semantic Scholar
Benzopyran sulfonamides as KV1.5 potassium channel blockers.
J. Lloyd, K. Atwal, Heather J. Finlay, M. Nyman +8 more
2007Bioorganic & Medicinal Chemistry Letters30 citations Open access
Semantic Scholar
Design, structure-activity relationships, X-ray crystal structure, and energetic contributions of a critical P1 pharmacophore: 3-chloroindole-7-yl-based factor Xa inhibitors.
Yan Shi, Doree Sitkoff, J. Zhang, H. Klei +16 more
2008Journal of Medicinal Chemistry28 citations Open access
Semantic Scholar
Discovery of ((S)-5-(methoxymethyl)-7-(1-methyl-1H-indol-2-yl)-2-(trifluoromethyl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)((S)-2-(3-methylisoxazol-5-yl)pyrrolidin-1-yl)methanone as a potent and selective I(Kur) inhibitor.
Heather J. Finlay, J. Lloyd, Wayne Vaccaro, A. Kover +16 more
2012Journal of Medicinal Chemistry26 citations Open access
Semantic Scholar
Dihydropyrazolopyrimidine inhibitors of K(V)1.5 (I(Kur)).
Wayne Vaccaro, T. Huynh, J. Lloyd, K. Atwal +6 more
2008Bioorganic & Medicinal Chemistry Letters25 citations Open access
Semantic Scholar
Benzodiazepine-based selective inhibitors of mitochondrial F1F0 ATP hydrolase.
L. Hamann, Charles Z. Ding, A. Miller, C. S. Madsen +6 more
2004Bioorganic & Medicinal Chemistry Letters24 citations Open access
Semantic Scholar
Potent non-nitrile dipeptidic dipeptidyl peptidase IV inhibitors.
L. Simpkins, Scott A. Bolton, Z. Pi, James C. Sutton +18 more
2007Bioorganic & Medicinal Chemistry Letters23 citations Open access
Semantic Scholar
Pharmacologic profile of the selective mitochondrial-K(ATP) opener BMS-191095 for treatment of acute myocardial ischemia.
G. Grover, K. Atwal
2006Cardiovascular Drug Reviews23 citations
Semantic Scholar
Aroylguanidine-based factor Xa inhibitors: the discovery of BMS-344577.
Yan Shi, Chi Li, Stephen P. O'connor, J. Zhang +16 more
2009Bioorganic & Medicinal Chemistry Letters22 citations Open access
Semantic Scholar
One-pot synthesis and conformational features of n,n'-disubstituted ketene aminals.
Yan Shi, J. Zhang, N. Grazier, P. Stein +6 more
2004Journal of Organic Chemistry20 citations
Semantic Scholar
Cardioselective antiischemic ATP-sensitive potassium channel openers. 4. Structure-activity studies on benzopyranylcyanoguanidines: replacement of the benzopyran portion.
K. Atwal, F. N. Ferrara, Charles Z. Ding, Gary J. Grover +4 more
1996Journal of Medicinal Chemistry20 citations
Semantic Scholar
Myocardial Protection with the ATP-Sensitive Potassium Channel Openers
K. Atwal
1996Current Medicinal Chemistry20 citations
Semantic Scholar
Aminoimidazoles as bioisosteres of acylguanidines: novel, potent, selective and orally bioavailable inhibitors of the sodium hydrogen exchanger isoform-1.
Saleem Ahmad, K. Ngu, D. Combs, Shung C. Wu +7 more
2004Bioorganic & Medicinal Chemistry Letters19 citations Open access
Semantic Scholar
One-pot synthesis of N,N′-disubstituted acylguanidines
J. Zhang, Yan Shi, P. Stein, K. Atwal +1 more
200218 citations
Semantic Scholar
Design and synthesis of 4-substituted benzamides as potent, selective, and orally bioavailable IKs blockers
J. Lloyd, Joan B. Schmidt, G. Rovnyak, Saleem Ahmad +16 more
200117 citations Open access
Semantic Scholar
Pyrano-[2,3b]-pyridines as potassium channel antagonists.
Heather J. Finlay, J. Lloyd, M. Nyman, M. Conder +3 more
2008Bioorganic & Medicinal Chemistry Letters16 citations Open access
Semantic Scholar
Ketene aminal-based lactam derivatives as a novel class of orally active FXa inhibitors.
Yan Shi, J. Zhang, P. Stein, Mengxiao Shi +18 more
2005Bioorganic & Medicinal Chemistry Letters16 citations Open access
Semantic Scholar
An isomerization—claisen rearrangement route to olefinic dicarbonyl starting materials for conjugate cyclization
G. Stork, K. Atwal
198216 citations
Semantic Scholar
Arylsulfonamidopiperidone derivatives as a novel class of factor Xa inhibitors.
Yan Shi, Stephen P. O'connor, Doree Sitkoff, J. Zhang +17 more
2011Bioorganic & Medicinal Chemistry Letters15 citations Open access
Semantic Scholar
Cyanoguanidine-based lactam derivatives as a novel class of orally bioavailable factor Xa inhibitors.
Yan Shi, J. Zhang, Mengxiao Shi, Stephen P. O'connor +15 more
2009Bioorganic & Medicinal Chemistry Letters15 citations Open access
Semantic Scholar
N-[1-Aryl-2-(1-imidazolo)ethyl]-guanidine derivatives as potent inhibitors of the bovine mitochondrial F1F0 ATP hydrolase.
K. Atwal, Saleem Ahmad, Charles Z. Ding, P. Stein +14 more
2004Bioorganic & Medicinal Chemistry Letters15 citations Open access
Semantic Scholar
Advances in the structure‐activity relationships, mechanisms of action, and therapeutic utilities of ATP‐sensitive potassium channel openers
K. Atwal
199415 citations
Semantic Scholar
Acid catalyzed intramolecular conjugate addition as a route to trans hydrindane systems
G. Stork, K. Atwal
198314 citations
Semantic Scholar
Phenacein--an angiotensin-converting enzyme inhibitor produced by a streptomycete. II. Isolation, structure determination and synthesis.
Wen-Chih Liu, W. Parker, S. S. Brandt, K. Atwal +1 more
1984Journal of antibiotics (Tokyo. 1968)13 citations Open access
Semantic Scholar
Triazolo and imidazo dihydropyrazolopyrimidine potassium channel antagonists.
Heather J. Finlay, Ji Jiang, Y. Caringal, A. Kover +9 more
2013Bioorganic & Medicinal Chemistry Letters12 citations Open access
Semantic Scholar
Tetrahydronaphthalene-derived amino alcohols and amino ketones as potent and selective inhibitors of the delayed rectifier potassium current IKs.
Saleem Ahmad, L. Doweyko, A. Ashfaq, F. N. Ferrara +13 more
2004Bioorganic & Medicinal Chemistry Letters12 citations
Semantic Scholar
(cis)-3-methyl-1,5-benzothiazepine-4-ones: potent analogs of the calcium channel blocker diltiazen
K. Atwal, S. T. Ahmed, D. Floyd, S. Moreland +1 more
199311 citations
Semantic Scholar
Aryl cyanoguanidine potassium channel openers
K. Atwal, S. Moreland, J. Mccullough, B. O'Reilly +2 more
199211 citations
Semantic Scholar
Synthesis and evaluation of acylguanidine FXa inhibitors.
Stephen P. O'connor, K. Atwal, Chi Li, E. Liu +5 more
2008Bioorganic & Medicinal Chemistry Letters10 citations Open access
Semantic Scholar
The discovery of a novel calcium channel blocker related to the structure of potassium channel opener cromakalim
K. Atwal, J. Mccullough, A. Hedberg, M. Conder +3 more
199210 citations
Semantic Scholar
Dihydropyrimidine Calcium Channel Blockers. Part 3. 3‐Carbamoyl‐4‐aryl‐1,2,3,4‐tetrahydro‐6‐methyl‐5‐pyrimidinecarboxylic Acid Esters as Orally Effective Antihypertensive Agents.
K. Atwal, B. Swanson, S. Unger, D. Floyd +3 more
199110 citations
Semantic Scholar
Amino(methyl) pyrrolidines as novel scaffolds for factor Xa inhibitors.
Yan Shi, Doree Sitkoff, J. Zhang, W. Han +13 more
2007Bioorganic & Medicinal Chemistry Letters9 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

P. Stein×13
Invite
P. Stein — researcher profile on SciRah
J. Lloyd×10
Invite
J. Lloyd — researcher profile on SciRah
M. Conder×10
Invite
M. Conder — researcher profile on SciRah
P. Levesque×9
Invite
P. Levesque — researcher profile on SciRah

×8

Invite

Yan Shi — researcher profile on SciRah

Invite

J. Zhang — researcher profile on SciRah

Heather J. Finlay×7

Invite

Heather J. Finlay — researcher profile on SciRah

Doree Sitkoff×7

Invite

Doree Sitkoff — researcher profile on SciRah

Saleem Ahmad×7

Invite

Saleem Ahmad — researcher profile on SciRah

Invite

E. Liu — researcher profile on SciRah

Invite

S. Seiler — researcher profile on SciRah

Invite

S. Bisaha — researcher profile on SciRah