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Heather J. Finlay · SciRah

Researcher profile · Semantic Scholar

Heather J. Finlay

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Heather J. Finlay — researcher profile on SciRah

h-index: 17
Works: 54
Citations: 1,418

Most-cited papers

Novel triterpenoids suppress inducible nitric oxide synthase (iNOS) and inducible cyclooxygenase (COX-2) in mouse macrophages.
N. Suh, T. Honda, Heather J. Finlay, A. Barchowsky +6 more
1998Cancer Research355 citations
Semantic Scholar
Synthetic oleanane and ursane triterpenoids with modified rings A and C: a series of highly active inhibitors of nitric oxide production in mouse macrophages.
T. Honda, BarbieAnn V. Rounds, L. Bore, Heather J. Finlay +5 more
2000Journal of Medicinal Chemistry256 citations
Semantic Scholar
Novel synthetic oleanane and ursane triterpenoids with various enone functionalities in ring A as inhibitors of nitric oxide production in mouse macrophages.
T. Honda, G. Gribble, N. Suh, Heather J. Finlay +5 more
2000Journal of Medicinal Chemistry129 citations
Semantic Scholar
New enone derivatives of oleanolic acid and ursolic acid as inhibitors of nitric oxide production in mouse macrophages
T. Honda, Heather J. Finlay, G. Gribble, N. Suh +1 more
199778 citations Open access
Semantic Scholar
Pyrrolidine amides of pyrazolodihydropyrimidines as potent and selective KV1.5 blockers.
J. Lloyd, Heather J. Finlay, Wayne Vacarro, Tram Hyunh +11 more
2010Bioorganic & Medicinal Chemistry Letters77 citations Open access
Semantic Scholar
Dihydropyrazolopyrimidines containing benzimidazoles as K(V)1.5 potassium channel antagonists.
J. Lloyd, Heather J. Finlay, K. Atwal, A. Kover +11 more
2009Bioorganic & Medicinal Chemistry Letters36 citations Open access
Semantic Scholar
In Vitro and In Vivo Evaluation of a Small-Molecule APJ (Apelin Receptor) Agonist, BMS-986224, as a Potential Treatment for Heart Failure
Peter S. Gargalovic, P. Wong, J. Onorato, Heather J. Finlay +12 more
2021Circulation: Heart Failure35 citations Open access
Semantic Scholar
Benzopyran sulfonamides as KV1.5 potassium channel blockers.
J. Lloyd, K. Atwal, Heather J. Finlay, M. Nyman +8 more
2007Bioorganic & Medicinal Chemistry Letters30 citations Open access
Semantic Scholar
Novel A-ring cleaved analogs of oleanolic and ursolic acids which affect growth regulation in NRP.152 prostate cells
Heather J. Finlay, T. Honda, G. Gribble, D. Danielpour +4 more
199730 citations Open access
Semantic Scholar
Diphenylpyridylethanamine (DPPE) derivatives as cholesteryl ester transfer protein (CETP) inhibitors.
L. Harikrishnan, Heather J. Finlay, Jennifer X. Qiao, Muthoni G. Kamau +22 more
2012Journal of Medicinal Chemistry26 citations Open access
Semantic Scholar
Discovery of ((S)-5-(methoxymethyl)-7-(1-methyl-1H-indol-2-yl)-2-(trifluoromethyl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)((S)-2-(3-methylisoxazol-5-yl)pyrrolidin-1-yl)methanone as a potent and selective I(Kur) inhibitor.
Heather J. Finlay, J. Lloyd, Wayne Vaccaro, A. Kover +16 more
2012Journal of Medicinal Chemistry26 citations Open access
Semantic Scholar
Dihydropyrazolopyrimidine inhibitors of K(V)1.5 (I(Kur)).
Wayne Vaccaro, T. Huynh, J. Lloyd, K. Atwal +6 more
2008Bioorganic & Medicinal Chemistry Letters25 citations Open access
Semantic Scholar
Expedient synthesis of unsaturated amide alkaloids from Piper spp: Exploring the scope of recent methodology
G. Strunz, Heather J. Finlay
199622 citations Open access
Semantic Scholar
Concise, efficient new synthesis of pipercide, an insecticidal unsaturated amide from Piper nigrum, and related compounds
G. Strunz, Heather J. Finlay
199420 citations
Semantic Scholar
Selective IKur Inhibitors for the Potential Treatment of Atrial Fibrillation: Optimization of the Phenyl Quinazoline Series Leading to Clinical Candidate 5-[5-Phenyl-4-(pyridin-2-ylmethylamino)quinazolin-2-yl]pyridine-3-sulfonamide.
P. Gunaga, J. Lloyd, S. Mummadi, A. Banerjee +27 more
2017Journal of Medicinal Chemistry19 citations Open access
Semantic Scholar
Discovery of a Hydroxypyridinone APJ Receptor Agonist as a Clinical Candidate.
James A. Johnson, Soong-Hoon Kim, Ji Jiang, Monique Phillips +14 more
2021Journal of Medicinal Chemistry18 citations Open access
Semantic Scholar
Oral Delivery of Highly Lipophilic, Poorly Water-Soluble Drugs: Self-Emulsifying Drug Delivery Systems to Improve Oral Absorption and Enable High-Dose Toxicology Studies of a Cholesteryl Ester Transfer Protein Inhibitor in Preclinical Species.
Xue-Qing Chen, T. Ziemba, Christine S. Huang, Ming Chang +8 more
2018Journal of Pharmacy and Science18 citations
Semantic Scholar
Synthesis of tertiary carbinamines
Muthoni G. Kamau, L. Harikrishnan, Heather J. Finlay, Jennifer X. Qiao +5 more
201216 citations
Semantic Scholar
Pyrano-[2,3b]-pyridines as potassium channel antagonists.
Heather J. Finlay, J. Lloyd, M. Nyman, M. Conder +3 more
2008Bioorganic & Medicinal Chemistry Letters16 citations Open access
Semantic Scholar
Synthesis of novel [3,2-b]indole fused oleanolic acids as potential inhibitors of cell proliferation
Heather J. Finlay, T. Honda, G. Gribble
200315 citations Open access
Semantic Scholar
Linking (Pyr)1apelin-13 pharmacokinetics to efficacy: Stabilization and measurement of a high clearance peptide in rodents.
J. Onorato, Carrie Xu, Xue-Qing Chen, Anne V. Rose +18 more
2019Analytical Biochemistry14 citations
Semantic Scholar
Identification of a Hydroxypyrimidinone Compound (21) as a Potent APJ Receptor Agonist for the Potential Treatment of Heart Failure.
Wei Meng, Z. Pi, R. Brigance, Karen A. Rossi +9 more
2021Journal of Medicinal Chemistry12 citations Open access
Semantic Scholar
Discovery of 5-Phenyl-N-(pyridin-2-ylmethyl)-2-(pyrimidin-5-yl)quinazolin-4-amine as a Potent I Kur Inhibitor.
Heather J. Finlay, James A. Johnson, J. Lloyd, Ji Jiang +11 more
2016ACS Medicinal Chemistry Letters12 citations Open access
Semantic Scholar
Triazolo and imidazo dihydropyrazolopyrimidine potassium channel antagonists.
Heather J. Finlay, Ji Jiang, Y. Caringal, A. Kover +9 more
2013Bioorganic & Medicinal Chemistry Letters12 citations Open access
Semantic Scholar
Partial Synthesis of Krukovines A and B, Triterpene Ketones Isolated from the Brazilian Medicinal Plant Maytenus krukovii
T. Honda, Heather J. Finlay, G. Gribble
199712 citations
Semantic Scholar
Identification of 6-Hydroxypyrimidin-4(1H)-one-3-carboxamides as Potent and Orally Active APJ Receptor Agonists.
Z. Pi, James A. Johnson, Wei Meng, Monique Phillips +10 more
2021ACS Medicinal Chemistry Letters11 citations Open access
Semantic Scholar
Synthesis of sarmentosine, an amide alkaloid from Piper sarmentosum
G. Strunz, Heather J. Finlay
199511 citations
Semantic Scholar
Triphenylethanamine Derivatives as Cholesteryl Ester Transfer Protein Inhibitors: Discovery of N-[(1R)-1-(3-Cyclopropoxy-4-fluorophenyl)-1-[3-fluoro-5-(1,1,2,2-tetrafluoroethoxy)phenyl]-2-phenylethyl]-4-fluoro-3-(trifluoromethyl)benzamide (BMS-795311).
Jennifer X. Qiao, Tammy C. Wang, L. Adam, A. Y. Chen +29 more
2015Journal of Medicinal Chemistry10 citations
Semantic Scholar
Identification of 6-Hydroxy-5-phenylsulfonylpyrimidin-4(1H)-one APJ Receptor Agonists.
George O. Tora, Ji Jiang, J. Bostwick, Peter S. Gargalovic +9 more
2021Bioorganic & Medicinal Chemistry Letters8 citations Open access
Semantic Scholar
Discovery and synthesis of tetrahydropyrimidinedione-4-carboxamides as endothelial lipase inhibitors.
Carol H. Hu, Tammy C. Wang, Jennifer X. Qiao, Lauren E. Haque +14 more
2018Bioorganic & Medicinal Chemistry Letters8 citations Open access
Semantic Scholar
Identification of Reversible Small Molecule Inhibitors of Endothelial Lipase (EL) which Demonstrate HDL-C Increase In Vivo.
George O. Tora, Soong-Hoon Kim, Z. Pi, James A. Johnson +23 more
2020Journal of Medicinal Chemistry7 citations Open access
Semantic Scholar
Sulfonylated Benzothiazoles as Inhibitors of Endothelial Lipase.
James A. Johnson, George O. Tora, Z. Pi, Monique Phillips +19 more
2018ACS Medicinal Chemistry Letters7 citations Open access
Semantic Scholar
PK/PD Disconnect Observed with a Reversible Endothelial Lipase Inhibitor.
J. Hangeland, Lynn M. Abell, L. Adam, Ji Jiang +16 more
2018ACS Medicinal Chemistry Letters6 citations Open access
Semantic Scholar
Design, synthesis and evaluation of phenethylaminoheterocycles as K(v)1.5 inhibitors.
James A. Johnson, N. Xu, Y. Jeon, Heather J. Finlay +9 more
2014Bioorganic & Medicinal Chemistry Letters6 citations Open access
Semantic Scholar
New Enone Derivatives of Oleanolic Acid and Ursolic Acid as Inhibitors of Nitric Oxide Production in Mouse Macrophages.
T. Honda, Heather J. Finlay, G. Gribble, N. Suh +1 more
19976 citations
Semantic Scholar
Pseudosaccharin amines as potent and selective KV1.5 blockers.
J. Lloyd, Heather J. Finlay, A. Kover, James A. Johnson +13 more
2015Bioorganic & Medicinal Chemistry Letters5 citations Open access
Semantic Scholar
Diphenylpyridylethanamine (DPPE)-based aminoheterocycles as cholesteryl ester transfer protein inhibitors.
Yufeng Wang, Wu Yang, Heather J. Finlay, L. Harikrishnan +14 more
2014Bioorganic & Medicinal Chemistry Letters5 citations Open access
Semantic Scholar
Benzothiazole-based compounds as potent endothelial lipase inhibitors.
W. Meng, L. Adam, Kamelia Behnia, Lei Zhao +7 more
2019Bioorganic & Medicinal Chemistry Letters3 citations Open access
Semantic Scholar
Identification of substituted benzothiazole sulfones as potent and selective inhibitors of endothelial lipase.
Soong-Hoon Kim, James A. Johnson, Ji Jiang, Brandon L. Parkhurst +22 more
2019Bioorganic & Medicinal Chemistry Letters3 citations Open access
Semantic Scholar
Discovery of hydroxyl 1,2-diphenylethanamine analogs as potent cholesterol ester transfer protein inhibitors.
Ji Jiang, Heather J. Finlay, James A. Johnson, L. Harikrishnan +11 more
2016Bioorganic & Medicinal Chemistry Letters3 citations Open access
Semantic Scholar
Abstract 2515: A Selective IKur Blocker, BMS-394136 Selectively Prolongs Atrial APD and Refractoriness in Beagles and Rabbits
D. Xing, Hua-Bin Sun, Jia-Long Zhu, Heather J. Finlay +2 more
20093 citations
Semantic Scholar
Discovery of Potent, Selective and Efficacious Aminopyrazole Inhibitors of PLK4.
Joon Won Jeong, Trevor Y. Chang, Jeremy M. Murray, Ryan L. Gonciarz +17 more
2025Journal of Medicinal Chemistry2 citations
Semantic Scholar
Chapter Eight - Current Approaches to the Treatment of Atrial Fibrillation
Heather J. Finlay
20142 citations
Semantic Scholar
Concise, Efficient New Synthesis of Pipercide, an Insecticidal Unsaturated Amide from Piper nigrum, and Related Compounds.
G. Strunz, Heather J. Finlay
19952 citations
Semantic Scholar
Discovery of a Lead Triphenylethanamine Cholesterol Ester Transfer Protein (CETP) Inhibitor.
Heather J. Finlay, Ji Jiang, R. Rampulla, M. Salvati +17 more
2019ACS Medicinal Chemistry Letters1 citations Open access
Semantic Scholar
Synthesis of Tertiary Carbinamines.
Muthoni G. Kamau, L. Harikrishnan, Heather J. Finlay, Jennifer X. Qiao +5 more
20121 citations
Semantic Scholar
Lead Optimization of an Aminopyrazole Scaffold to EXEL-1855, a Highly Selective PLK4 Inhibitor with Potent Antitumor Efficacy
Ryan L. Gonciarz, Trevor Y. Chang, A. S. St. Amant, Joon Won Jeong +22 more
2026Journal of Medicinal Chemistry0 citations
Semantic Scholar
Design and preparation of N-linked hydroxypyridine-based APJ agonists.
J. M. Richter, J. Bates, Peter S. Gargalovic, J. Onorato +5 more
2022Bioorganic & Medicinal Chemistry Letters0 citations Open access
Semantic Scholar
The Discovery and Chemical Development of BMS-919373: A Selective I Kur Inhibitor for the Potential Treatment of Atrial Fibrillation
Heather J. Finlay, Scott A. Savage, Jason M. Stevens, S. Wisniewski +1 more
20200 citations
Semantic Scholar
Corrigendum to "Identification of substituted benzothiazole sulfones as potent and selective inhibitors of endothelial lipase" [Bioorg. Med. Chem. Lett. 29 (2019) 1918-1921].
Soong-Hoon Kim, James A. Johnson, Ji Jiang, Brandon L. Parkhurst +22 more
2019Bioorganic & Medicinal Chemistry Letters0 citations
Semantic Scholar

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