K. Garlid

Most-cited papers

Cardioprotective effect of diazoxide and its interaction with mitochondrial ATP-sensitive K+ channels. Possible mechanism of cardioprotection.
K. Garlid, P. Paucek, Vladimir Yarov-Yarovoy, H. Murray +5 more
1997Circulation Research1,121 citations
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ATP-Sensitive potassium channels: a review of their cardioprotective pharmacology.
G. Grover, K. Garlid
2000Journal of Molecular and Cellular Cardiology418 citations
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Bioenergetic consequences of opening the ATP-sensitive K(+) channel of heart mitochondria.
A. Kowaltowski, Subramaniam Seetharaman, P. Paucek, K. Garlid
2001American Journal of Physiology. Heart and Circulatory Physiology372 citations
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Mitochondrial potassium transport: the K(+) cycle.
K. Garlid, P. Paucek
2003Biochimica et Biophysica Acta358 citations Open access
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Mitochondrial potassium transport: the role of the mitochondrial ATP-sensitive K(+) channel in cardiac function and cardioprotection.
K. Garlid, P. Dos Santos, Zi-Jian Xie, A. D. Costa +1 more
2003Biochimica et Biophysica Acta349 citations Open access
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On the Mechanism of Fatty Acid-induced Proton Transport by Mitochondrial Uncoupling Protein (*)
K. Garlid, D. E. Orosz, M. Modriansky, S. Vassanelli +1 more
1996Journal of Biological Chemistry328 citations Open access
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Transport Function and Regulation of Mitochondrial Uncoupling Proteins 2 and 3*
M. Jabůrek, M. Varecha, Ruth E. Gimeno, M. Dembski +5 more
1999Journal of Biological Chemistry325 citations Open access
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The Mitochondrial K Channel as a Receptor for Potassium Channel Openers (*)
K. Garlid, P. Paucek, Vladimir Yarov-Yarovoy, Xiao-Cheng Sun +1 more
1996Journal of Biological Chemistry316 citations Open access
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Protein Kinase G Transmits the Cardioprotective Signal From Cytosol to Mitochondria
A. D. Costa, K. Garlid, I. West, T. Lincoln +3 more
2005Circulation Research311 citations Open access
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Identification and Properties of a Novel Intracellular (Mitochondrial) ATP-sensitive Potassium Channel in Brain*
R. Bajgar, Subramaniam Seetharaman, A. Kowaltowski, K. Garlid +1 more
2001Journal of Biological Chemistry287 citations Open access
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State-dependent inhibition of the mitochondrial KATP channel by glyburide and 5-hydroxydecanoate.
M. Jabůrek, Vladimir Yarov-Yarovoy, P. Paucek, K. Garlid
1998Journal of Biological Chemistry267 citations
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Mechanisms by which opening the mitochondrial ATP- sensitive K(+) channel protects the ischemic heart.
P. Dos Santos, A. Kowaltowski, M. Laclau, S. Seetharaman +5 more
2002American Journal of Physiology. Heart and Circulatory Physiology242 citations
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Intramitochondrial signaling: interactions among mitoKATP, PKCepsilon, ROS, and MPT.
A. D. Costa, K. Garlid
2008American Journal of Physiology. Heart and Circulatory Physiology227 citations Open access
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Opening mitoKATP increases superoxide generation from complex I of the electron transport chain.
A. Andrukhiv, A. D. Costa, I. West, K. Garlid
2006American Journal of Physiology. Heart and Circulatory Physiology222 citations
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Cation transport in mitochondria--the potassium cycle.
K. Garlid
1996Biochimica et Biophysica Acta216 citations Open access
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The Mechanism by Which the Mitochondrial ATP-sensitive K+ Channel Opening and H2O2 Inhibit the Mitochondrial Permeability Transition*
A. D. Costa, Regina Jakob, C. L. Costa, Ksenia Andrukhiv +2 more
2006Journal of Biological Chemistry212 citations Open access
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Fatty acid cycling mechanism and mitochondrial uncoupling proteins.
P. Ježek, H. Engstová, M. Z̆ác̆ková, A. Vercesi +3 more
1998Biochimica et Biophysica Acta209 citations Open access
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The direct physiological effects of mitoK(ATP) opening on heart mitochondria.
A. D. Costa, Casey L. Quinlan, A. Andrukhiv, I. West +2 more
2006American Journal of Physiology. Heart and Circulatory Physiology208 citations
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The mitochondrial ROMK channel is a molecular component of Mitokatp
D. B. Foster, A. Ho, J. Rucker, A. Garlid +4 more
2012Circulation Research201 citations Open access
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Cardioprotective Signaling to Mitochondria
K. Garlid, A. D. Costa, Casey L. Quinlan, S. Pierre +1 more
2008Journal of Molecular and Cellular Cardiology196 citations Open access
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Opening mitochondrial KATP in the heart – what happens, and what does not happen
K. Garlid
2000Basic Research in Cardiology195 citations
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The mechanism of proton transport mediated by mitochondrial uncoupling proteins
K. Garlid, M. Jabůrek, P. Ježek
1998FEBS Letters170 citations
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Mitochondrial PKC&egr; and Mitochondrial ATP-Sensitive K+ Channel Copurify and Coreconstitute to Form a Functioning Signaling Module in Proteoliposomes
M. Jabůrek, A. D. Costa, Jana R. Burton, C. L. Costa +1 more
2006Circulation Research158 citations
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Opening of ATP-sensitive potassium channels causes generation of free radicals in vascular smooth muscle cells
M. Krenz, O. Oldenburg, Holly Wimpee, M. Cohen +4 more
2002Basic Research in Cardiology146 citations
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cGMP signalling in pre- and post-conditioning: the role of mitochondria.
A. D. Costa, S. Pierre, M. Cohen, J. Downey +1 more
2008Cardiovascular Research144 citations Open access
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Mitochondrial Uncoupling Proteins: Subtle Regulators of Cellular Redox Signaling
P. Ježek, B. Holendová, K. Garlid, M. Jabůrek
2018Antioxidants and Redox Signaling137 citations Open access
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How do uncoupling proteins uncouple?
K. Garlid, M. Jabůrek, Petr Ježek, Miroslav Vařecha
2000Biochimica et Biophysica Acta129 citations Open access
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Cardioprotection by ischemic preconditioning preserves mitochondrial function and functional coupling between adenine nucleotide translocase and creatine kinase.
M. Laclau, S. Boudina, J. Thambo, L. Tariosse +5 more
2001Journal of Molecular and Cellular Cardiology119 citations
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Transport of anions and protons by the mitochondrial uncoupling protein and its regulation by nucleotides and fatty acids. A new look at old hypotheses.
Petr Ježek, D. E. Orosz, M. Modriansky, K. Garlid
1994Journal of Biological Chemistry116 citations Open access
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Involvement of mitogen-activated protein kinases and reactive oxygen species in the inotropic action of ouabain on cardiac myocytes. A potential role for mitochondrial KATP channels
Jiang Tian, Jiang Liu, K. Garlid, J. Shapiro +1 more
2004Molecular and Cellular Biochemistry112 citations
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Inhibition of the Mitochondrial KATP Channel by Long-chain Acyl-CoA Esters and Activation by Guanine Nucleotides*
P. Paucek, Vladimir Yarov-Yarovoy, Xiao-Cheng Sun, K. Garlid
1996Journal of Biological Chemistry106 citations Open access
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Functional Distinctions between the Mitochondrial ATP-dependent K+ Channel (mitoKATP) and Its Inward Rectifier Subunit (mitoKIR)*
G. Mironova, A. Negoda, B. Marinov, P. Paucek +4 more
2004Journal of Biological Chemistry104 citations Open access
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Pharmacologic characterization of BMS-191095, a mitochondrial K(ATP) opener with no peripheral vasodilator or cardiac action potential shortening activity.
G. Grover, A. D'Alonzo, K. Garlid, R. Bajgar +7 more
2001Journal of Pharmacology and Experimental Therapeutics99 citations
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Hydroperoxy Fatty Acid Cycling Mediated by Mitochondrial Uncoupling Protein UCP2*
M. Jabůrek, S. Miyamoto, P. di Mascio, K. Garlid +1 more
2004Journal of Biological Chemistry98 citations Open access
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Mammalian mitochondrial uncoupling proteins.
P. Ježek, K. Garlid
1998International Journal of Biochemistry and Cell Biology97 citations
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Identification by Site-directed Mutagenesis of Three Arginines in Uncoupling Protein That Are Essential for Nucleotide Binding and Inhibition*
M. Modriansky, D. L. Murdza-Inglis, H. Patel, K. B. Freeman +1 more
1997Journal of Biological Chemistry97 citations Open access
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Ouabain protects rat hearts against ischemia-reperfusion injury via pathway involving src kinase, mitoKATP, and ROS.
P. Pasdois, Casey L. Quinlan, Abraham Rissa, L. Tariosse +5 more
2007American Journal of Physiology. Heart and Circulatory Physiology95 citations
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On the regulation of K+ uniport in intact mitochondria by adenine nucleotides and nucleotide analogs.
A. Beavis, Yun Lu, K. Garlid
1993Journal of Biological Chemistry94 citations Open access
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Evidence that spermine, spermidine, and putrescine are transported electrophoretically in mitochondria by a specific polyamine uniporter.
Antonio Toninello, L. D. Via, D. Siliprandi, K. Garlid
1992Journal of Biological Chemistry91 citations Open access
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The mitochondrial KATP channel – fact or fiction?
K. Garlid, A. Halestrap
2012Journal of Molecular and Cellular Cardiology86 citations Open access
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Conditioning the heart induces formation of signalosomes that interact with mitochondria to open mitoKATP channels.
Casey L. Quinlan, A. D. Costa, C. L. Costa, S. Pierre +2 more
2008American Journal of Physiology. Heart and Circulatory Physiology81 citations Open access
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Reconstitution of Recombinant Uncoupling Proteins
M. Jabůrek, K. Garlid
2003Journal of Biological Chemistry81 citations Open access
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AA1, a newly synthesized monovalent lipophilic cation, expresses potent in vivo antitumor activity.
Xiao-Cheng Sun, James R. Wong, Kai-Li Song, Julian Hu +2 more
1994Cancer Research81 citations
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Ouabain triggers preconditioning through activation of the Na+,K+-ATPase signaling cascade in rat hearts.
S. Pierre, Chang-Jun Yang, Zhaokan Yuan, J. Seminerio +4 more
2007Cardiovascular Research80 citations Open access
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Mechanism of uncoupling protein action.
K. Garlid, M. Jabůrek, Petr Ježek
2001Biochemical Society Transactions78 citations
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Reconstitution, identification, purification, and immunological characterization of the 110-kDa Na+/Ca2+ antiporter from beef heart mitochondria.
Wei-Hua Li, Zia Shariat-Madar, M. Powers, Xiao-Cheng Sun +2 more
1992Journal of Biological Chemistry75 citations Open access
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A structure–activity study of fatty acid interaction with mitochondrial uncoupling protein
P. Ježek, M. Modriansky, K. Garlid
1997FEBS Letters72 citations Open access
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Mitochondrial reactive oxygen species: which ROS signals cardioprotection?
A. Garlid, M. Jabůrek, Jeremy P. Jacobs, K. Garlid
2013American Journal of Physiology. Heart and Circulatory Physiology68 citations Open access
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Inactive fatty acids are unable to flip‐flop across the lipid bilayer
P. Ježek, M. Modriansky, K. Garlid
1997FEBS Letters68 citations Open access
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On the mechanism by which bupivacaine conducts protons across the membranes of mitochondria and liposomes.
X. Sun, K. Garlid
1992Journal of Biological Chemistry63 citations Open access
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