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W. Frederiks · SciRah

Researcher profile · Semantic Scholar

W. Frederiks

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W. Frederiks — researcher profile on SciRah

h-index: 35
Works: 164
Citations: 4,043

Most-cited papers

The role of gelatinases in colorectal cancer progression and metastasis.
O. Mook, W. Frederiks, C. V. van Noorden
2004Biochimica et Biophysica Acta552 citations
Semantic Scholar
Metastasis is promoted by a bioenergetic switch: New targets for progressive renal cell cancer
S. Langbein, W. Frederiks, A. zur Hausen, J. Popa +4 more
2008International Journal of Cancer132 citations Open access
Semantic Scholar
Metabolic Mapping of Proteinase Activity with Emphasis on In Situ Zymography of Gelatinases
W. Frederiks, O. Mook
2004Journal of Histochemistry and Cytochemistry126 citations Open access
Semantic Scholar
Visualization of early events in tumor formation of eGFP‐transfected rat colon cancer cells in liver
O. Mook, J. van Marle, Heleen Vreeling-Sindelárová, R. Jonges +2 more
2003Hepatology125 citations Open access
Semantic Scholar
Nitric oxide synthase activity.
W. Frederiks
1996Journal of Histochemistry and Cytochemistry125 citations Open access
Semantic Scholar
In Situ Localization of Gelatinolytic Activity in the Extracellular Matrix of Metastases of Colon Cancer in Rat Liver Using Quenched Fluorogenic DQ-gelatin
O. Mook, Claudia Van Overbeek, Eleonora G Ackema, F. van Maldegem +1 more
2003Journal of Histochemistry and Cytochemistry113 citations Open access
Semantic Scholar
Modulation of pentose phosphate pathway during cell cycle progression in human colon adenocarcinoma cell line HT29
Pedro Vizán, G. Alcarraz‐Vizán, S. Díaz‐Moralli, O. Solovjeva +2 more
2009International Journal of Cancer101 citations Open access
Semantic Scholar
Conversion of xanthine dehydrogenase into xanthine oxidase in rat liver and plasma at the onset of reperfusion after ischemia
A. Kooij, Henry J. Schiller, Martin Schijns, C. V. van Noorden +1 more
1994Hepatology91 citations Open access
Semantic Scholar
Tissue-type plasminogen activator modulates inflammatory responses and renal function in ischemia reperfusion injury.
J. Roelofs, K. Rouschop, J. Leemans, N. Claessen +5 more
2005Journal of the American Society of Nephrology85 citations
Semantic Scholar
Intracellular free radical production in synovial T lymphocytes from patients with rheumatoid arthritis.
P. Remans, M. V. van Oosterhout, T. Smeets, M. Sanders +5 more
2005Arthritis & Rheumatism82 citations
Semantic Scholar
Endotoxin and interleukin‐1 related hepatic inflammatory response promotes liver failure after partial hepatectomy
M. Boermeester, Irene H. Straatsburg, A. Houdijk, Catharina L Meyer +4 more
1995Hepatology71 citations
Semantic Scholar
Renal cell carcinoma and oxidative stress: The lack of peroxisomes.
W. Frederiks, K. Bosch, K. Hoeben, J. van Marle +1 more
2010Acta Histochemica57 citations
Semantic Scholar
Kupffer cells and not liver sinusoidal endothelial cells prevent lentiviral transduction of hepatocytes.
N. P. van Til, D. Markusic, R. van der Rijt, C. Kunne +5 more
2005Molecular Therapy56 citations Open access
Semantic Scholar
Elevated activity of the oxidative and non‐oxidative pentose phosphate pathway in (pre)neoplastic lesions in rat liver
W. Frederiks, Pedro Vizán, K. Bosch, Heleen Vreeling-Sindelárová +2 more
2008International journal of experimental pathology (Print)55 citations Open access
Semantic Scholar
Complement activation induced by ischemia-reperfusion in humans: a study in patients undergoing partial hepatectomy.
I. Straatsburg, M. Boermeester, G. Wolbink, T. V. van Gulik +3 more
1998Journal of Hepatology51 citations
Semantic Scholar
UvA-DARE ( Digital Academic Repository ) In situ detection of spontaneous superoxide anion and singlet oxygen production by mitochondria in rat liver and small
I. Vogels, K. Bosch, Heleen Vreeling-Sindelárová, W. Frederiks
199746 citations
Semantic Scholar
Localization of superoxide dismutase activity in rat tissues.
W. Frederiks, K. Bosch
1997Free Radical Biology & Medicine45 citations Open access
Semantic Scholar
Measurements of T1 and T2 relaxation times of colon cancer metastases in rat liver at 7 T
G. Gambarota, Andor Veltien, H. V. van Laarhoven, M. Philippens +4 more
2004Magnetic Resonance Materials in Physics, Biology and Medicine44 citations
Semantic Scholar
Metabolic Control Analysis Aimed at the Ribose Synthesis Pathways of Tumor Cells: A New Strategy for Antitumor Drug Development
J. Boren, A. R. Montoya, P. De Atauri, B. Comin-Anduix +5 more
2004Molecular Biology Reports42 citations
Semantic Scholar
Regulation of protein secretion into bile: studies in mice with a disrupted mdr2 p-glycoprotein gene.
A. K. Groen, M. V. van Wijland, W. Frederiks, J. J. Smit +2 more
1995Gastroenterology42 citations Open access
Semantic Scholar
Protective effect of silymarin on rat liver injury induced by ischemia
Chuan-Ging Wu, R. Chamuleau, K. Bosch, W. Frederiks
1993Virchows Archiv B Cell Pathology Including Molecular Pathology42 citations
Semantic Scholar
Quantitative changes in acid phosphatase, alkaline phosphatase and 5'-nucleotidase activity in rat liver after experimentally induced cholestasis.
W. Frederiks, C. V. van Noorden, D. Aronson, F. Marx +4 more
2008Liver39 citations
Semantic Scholar
Hyaluronic acid uptake in the assessment of sinusoidal endothelial cell damage after cold storage and normothermic reperfusion of rat livers
M. Reinders, B. Wagensveld, T. M. Gulik, W. Frederiks +3 more
1996Transplant International39 citations
Semantic Scholar
NADPH Production by the Pentose Phosphate Pathway in the Zona Fasciculata of Rat Adrenal Gland
W. Frederiks, Intan P. Kümmerlin, K. Bosch, Heleen Vreeling-Sindelárová +2 more
2007Journal of Histochemistry and Cytochemistry36 citations Open access
Semantic Scholar
The value of enzyme leakage for the prediction of necrosis in liver ischemia
W. Frederiks, G. Myagkaya, K. Bosch, G. Fronik +3 more
2004Histochemistry36 citations
Semantic Scholar
Ultrastructural localization of xanthine oxidoreductase activity in isolated rat liver cells.
W. Frederiks, H. Vreeling-Sindelárová
2002Acta Histochemica36 citations
Semantic Scholar
Localization of Glucose-6-phosphate Dehydrogenase Activity on Ribosomes of Granular Endoplasmic Reticulum, in Peroxisomes and Peripheral Cytoplasm of Rat Liver Parenchymal Cells
W. Frederiks, Heleen Vreeling-Sindelárová
2001The Histochemical Journal36 citations
Semantic Scholar
Post-translational Regulation of Glucose-6-phosphate Dehydrogenase Activity in (Pre)neoplastic Lesions in Rat Liver
W. Frederiks, K. Bosch, J. D. de Jong, C. V. van Noorden
2003Journal of Histochemistry and Cytochemistry34 citations Open access
Semantic Scholar
A quantitative histochemical study of xanthine oxidase activity in rat liver using the cerium capture method in the presence of polyvinyl alcohol.
W. Frederiks, K. Bosch, R. J. M. Van Den Munckhof, C. V. van Noorden
1994Journal of Histochemistry and Cytochemistry34 citations
Semantic Scholar
Posttranslational Regulation of Glucose-6-phosphate Dehydrogenase Activity in Tongue Epithelium
E. Biagiotti, K. Bosch, P. Ninfali, W. Frederiks +1 more
2000Journal of Histochemistry and Cytochemistry33 citations Open access
Semantic Scholar
Preservation of canine liver grafts using HTK solution.
T. V. van Gulik, M. Reinders, R. Nio, W. Frederiks +2 more
1994Transplantation30 citations
Semantic Scholar
No attenuation of ischemic and reperfusion injury in Kupffer cell-depleted, cold-preserved rat livers.
M. Reinders, B. V. van Wagensveld, T. V. van Gulik, Noortje P. M. Corssmit +4 more
1997Transplantation29 citations Open access
Semantic Scholar
Localization of uric acid oxidase activity in core and matrix of peroxisomes as detected in unfixed cryostat sections of rat liver.
R. J. M. Van Den Munckhof, H. Vreeling-Sindelárová, J. Schellens, W. Frederiks
1994Journal of Histochemistry and Cytochemistry29 citations Open access
Semantic Scholar
Ultrastructural localization of xanthine oxidase activity in the digestive tract of the rat
R. J. M. Van Den Munckhof, H. Vreeling-Sindelárová, J. Schellens, C. V. van Noorden +1 more
1995The Histochemical Journal28 citations
Semantic Scholar
In Situ Localization of Transketolase Activity in Epithelial Cells of Different Rat Tissues and Subcellularly in Liver Parenchymal Cells
J. Boren, A. Ramos-Montoya, K. Bosch, H. Vreeling +4 more
2006Journal of Histochemistry and Cytochemistry27 citations
Semantic Scholar
In situ substrate specificity and ultrastructural localization of polyamine oxidase activity in unfixed rat tissues.
R. J. M. Van Den Munckhof, M. Denyn, W. Tigchelaar-Gutter, R. Schipper +3 more
1995Journal of Histochemistry and Cytochemistry27 citations Open access
Semantic Scholar
The proportion of xanthine oxidase activity of total xanthine oxidoreductase activity in situ remains constant in rat liver under various (patho)physiological conditions
W. Frederiks, K. Bosch
1996Hepatology26 citations Open access
Semantic Scholar
Interactions between colon cancer cells and hepatocytes in rats in relation to metastasis
O. Mook, J. van Marie, R. Jonges, H. Vreeling-Sindelárová +2 more
2008Journal of Cellular and Molecular Medicine25 citations Open access
Semantic Scholar
Enhanced light microscopic visualization of oxidase activity with the cerium capture method
R. Gossrau, C. V. van Noorden, W. Frederiks
2004Histochemistry23 citations
Semantic Scholar
Alpha glutathione S-transferase as novel parameter for hepatocellular damage in the isolated perfused rat liver.
B. V. van Wagensveld, J. J. G. Scheepers, T. V. van Gulik, W. Frederiks +3 more
1997Transplantation Proceedings23 citations Open access
Semantic Scholar
The role of xanthine oxidase in
W. Frederiks, K. Bosch
199522 citations
Semantic Scholar
Hyperthermia, radiation carcinogenesis and the protective potential of vitamin A and N-acetylcysteine
P. Sminia, A. H. W. van der Kracht, W. Frederiks, W. Jansen
2005Journal of Cancer Research and Clinical Oncology21 citations Open access
Semantic Scholar
Improved Localization of Glucose-6-phosphate Dehydrogenase Activity in Cells with 5-Cyano-2, 3-ditolyl-tetrazolium Chloride as Fluorescent Redox Dye Reveals its Cell Cycle-dependent Regulation
W. Frederiks, J. van Marle, C. V. van Oven, B. Comin-Anduix +1 more
2006Journal of Histochemistry and Cytochemistry19 citations Open access
Semantic Scholar
The role of xanthine oxidase in ischemia/reperfusion damage of rat liver.
W. Frederiks, K. Bosch
1995Histology and Histopathology19 citations
Semantic Scholar
Early effects of high doses of retinol (vitamin A) on the in situ cellular metabolism in rat liver.
K. Lettinga, W. Gutter, C. V. van Noorden, J. Schellens +1 more
2008Liver17 citations
Semantic Scholar
Oxygen Insensitivity of the Histochemical Assay of Glucose-6-phosphate Dehydrogenase Activity for the Detection of (Pre)Neoplasm in Rat Liver
J. D. de Jong, W. Frederiks, C. V. van Noorden
2001Journal of Histochemistry and Cytochemistry17 citations Open access
Semantic Scholar
Loss of Peroxisomes Causes Oxygen Insensitivity of the Histochemical Assay of Glucose-6-Phosphate Dehydrogenase Activity to Detect Cancer Cells
W. Frederiks, Heleen Vreeling-Sindelárová, C. V. van Noorden
2007Journal of Histochemistry and Cytochemistry16 citations Open access
Semantic Scholar
Histochemistry of reactive oxygen-species (ROS)-generating oxidases in cutaneous and mucous epithelia of laboratory rodents with special reference to xanthine oxidase
R. Gossrau, W. Frederiks, C. V. van Noorden
2004Histochemistry15 citations
Semantic Scholar
Influence of nutritional state on ischemic damage in rat liver.
W. Frederiks, G. Fronik, F. Marx, J. James
2008Liver13 citations
Semantic Scholar
Promotion of colon cancer metastases in rat liver by fish oil diet is not due to reduced stroma formation
L. Klieverik, O. Fehres, P. Griffini, C. V. van Noorden +1 more
2004Clinical and Experimental Metastasis13 citations
Semantic Scholar

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