Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

D. Markusic · SciRah

Researcher profile · Semantic Scholar

D. Markusic

Share profile

D. Markusic — researcher profile on SciRah

h-index: 27
Works: 79
Citations: 3,081

Most-cited papers

The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9-dependent innate immune responses in the liver.
Ashley T. Martino, Masataka Suzuki, D. Markusic, I. Zolotukhin +6 more
2011Blood235 citations Open access
Semantic Scholar
Clinical development of gene therapy: results and lessons from recent successes
Sandeep R. P. Kumar, D. Markusic, Moanaro Biswas, K. High +1 more
2016Molecular Therapy: Methods & Clinical Development229 citations Open access
Semantic Scholar
Mitochondrial DNA polymerase γ deficiency and mtDNA depletion in a child with Alpers' syndrome
R. Naviaux, W. Nyhan, B. Barshop, J. Poulton +3 more
1999176 citations Open access
Semantic Scholar
Autism Associated With the Mitochondrial DNA G8363A Transfer RNALys Mutation
W. D. Graf, J. Marín-García, H.-G. Gao, S. Pizzo +5 more
2000Journal of Child Neurology170 citations
Semantic Scholar
Engineered AAV vector minimizes in vivo targeting of transduced hepatocytes by capsid-specific CD8+ T cells.
Ashley T. Martino, E. Basner-Tschakarjan, D. Markusic, Jonathan D. Finn +9 more
2013Blood164 citations Open access
Semantic Scholar
Update on clinical gene therapy for hemophilia.
G. Perrin, R. Herzog, D. Markusic
2019Blood158 citations Open access
Semantic Scholar
High-efficiency transduction and correction of murine hemophilia B using AAV2 vectors devoid of multiple surface-exposed tyrosines.
D. Markusic, R. Herzog, G. Aslanidi, Brad E. Hoffman +9 more
2010Molecular Therapy137 citations Open access
Semantic Scholar
Effective gene therapy for haemophilic mice with pathogenic factor IX antibodies
D. Markusic, Brad E. Hoffman, G. Perrin, Sushrusha Nayak +4 more
2013EMBO Molecular Medicine119 citations Open access
Semantic Scholar
Mitochondrial DNA polymerase gamma deficiency and mtDNA depletion in a child with Alpers' syndrome.
R. Naviaux, W. Nyhan, B. Barshop, J. Poulton +3 more
1999Annals of Neurology119 citations
Semantic Scholar
Tolerance Induction to Factor VIII by Transient Co-administration with Rapamycin
B. Moghimi, B. Sack, Sushrusha Nayak, D. Markusic +2 more
2011Journal of Thrombosis and Haemostasis97 citations Open access
Semantic Scholar
Gene Therapy-Induced Antigen-Specific Tregs Inhibit Neuro-inflammation and Reverse Disease in a Mouse Model of Multiple Sclerosis
G. Keeler, Sandeep R. P. Kumar, Brett Palaschak, Emily L. Silverberg +3 more
2017Molecular Therapy92 citations Open access
Semantic Scholar
Comparison of single regulated lentiviral vectors with rtTA expression driven by an autoregulatory loop or a constitutive promoter
D. Markusic, R. Oude-Elferink, Atze T. Das, B. Berkhout +1 more
2005Nucleic Acids Research88 citations Open access
Semantic Scholar
Immune Response Mechanisms against AAV Vectors in Animal Models
Ashley T. Martino, D. Markusic
2019Molecular Therapy: Methods & Clinical Development85 citations Open access
Semantic Scholar
Unique roles of TLR9- and MyD88-dependent and -independent pathways in adaptive immune responses to AAV-mediated gene transfer
G. Rogers, Masataka Suzuki, I. Zolotukhin, D. Markusic +4 more
2015Journal of Innate Immunity82 citations Open access
Semantic Scholar
Transient B Cell Depletion or Improved Transgene Expression by Codon Optimization Promote Tolerance to Factor VIII in Gene Therapy
B. Sack, SHERIN. N. Merchant, D. Markusic, A. Nathwani +3 more
2012PLoS ONE79 citations Open access
Semantic Scholar
Liver Induced Transgene Tolerance with AAV Vectors
G. Keeler, D. Markusic, Brad E. Hoffman
2017Cellular Immunology73 citations Open access
Semantic Scholar
Vector design Tour de Force: integrating combinatorial and rational approaches to derive novel adeno-associated virus variants.
Damien Marsic, L. Govindasamy, Seth Currlin, D. Markusic +4 more
2014Molecular Therapy73 citations Open access
Semantic Scholar
Development of Gene Transfer for Induction of Antigen-specific Tolerance
B. Sack, R. Herzog, C. Terhorst, D. Markusic
2014Molecular Therapy: Methods & Clinical Development71 citations Open access
Semantic Scholar
Ex vivo expanded autologous polyclonal regulatory T cells suppress inhibitor formation in hemophilia
Debalina Sarkar, Moanaro Biswas, Gongxian Liao, Howard R. Seay +6 more
2014Molecular Therapy: Methods & Clinical Development70 citations Open access
Semantic Scholar
Type I IFN Sensing by cDCs and CD4+ T Cell Help Are Both Requisite for Cross-Priming of AAV Capsid-Specific CD8+ T Cells.
Jamie L. Shirley, G. Keeler, A. Sherman, I. Zolotukhin +6 more
2019Molecular Therapy69 citations Open access
Semantic Scholar
Synergy between rapamycin and FLT3 ligand enhances plasmacytoid dendritic cell-dependent induction of CD4+CD25+FoxP3+ Treg.
Moanaro Biswas, Debalina Sarkar, Sandeep R. P. Kumar, Sushrusha Nayak +5 more
2015Blood67 citations Open access
Semantic Scholar
Tolerance Induction to Cytoplasmic β-Galactosidase by Hepatic AAV Gene Transfer — Implications for Antigen Presentation and Immunotoxicity
Ashley T. Martino, Sushrusha Nayak, Brad E. Hoffman, Mario Cooper +5 more
2009PLoS ONE59 citations Open access
Semantic Scholar
Potential for cellular stress response to hepatic factor VIII expression from AAV vector
I. Zolotukhin, D. Markusic, Brett Palaschak, Brad E. Hoffman +2 more
2016Molecular Therapy: Methods & Clinical Development56 citations Open access
Semantic Scholar
Kupffer cells and not liver sinusoidal endothelial cells prevent lentiviral transduction of hepatocytes.
N. P. van Til, D. Markusic, R. van der Rijt, C. Kunne +5 more
2005Molecular Therapy56 citations Open access
Semantic Scholar
Synthetic Gene Regulation Circuits for Control of Cell Expansion
T. May, Milada Butueva, Sara Bantner, D. Markusic +5 more
2009Tissue Engineering. Part A54 citations
Semantic Scholar
Liver-Directed Adeno-Associated Viral Gene Therapy for Hemophilia
D. Markusic, R. Herzog
2012Journal of genetic syndrome & gene therapy32 citations Open access
Semantic Scholar
Combination Therapy for Inhibitor Reversal in Haemophilia A Using Monoclonal Anti-CD20 and Rapamycin
Moanaro Biswas, G. Rogers, A. Sherman, B. Byrne +3 more
2016Thrombosis and Haemostasis28 citations Open access
Semantic Scholar
AAV-Mediated Gene Delivery to the Liver: Overview of Current Technologies and Methods.
Brett Palaschak, R. Herzog, D. Markusic
2019Methods in molecular biology27 citations
Semantic Scholar
Sand DNA—a genetic library of life at the water's edge
R. Naviaux, B. Good, J. Mcpherson, D. Steffen +3 more
200525 citations
Semantic Scholar
B Cell Depletion Eliminates FVIII Memory B Cells and Enhances AAV8-coF8 Immune Tolerance Induction When Combined With Rapamycin
Moanaro Biswas, Brett Palaschak, Sandeep R. P. Kumar, J. Rana +1 more
2020Frontiers in Immunology23 citations Open access
Semantic Scholar
Sensitive Assay for Mitochondrial DNA Polymerase γ
R. Naviaux, D. Markusic, B. Barshop, W. Nyhan +1 more
199922 citations
Semantic Scholar
Evaluation of engineered AAV capsids for hepatic factor IX gene transfer in murine and canine models
D. Markusic, T. Nichols, E. Merricks, Brett Palaschak +5 more
2017Journal of Translational Medicine20 citations Open access
Semantic Scholar
Separating Lentiviral Vector Injection and Induction of Gene Expression in Time, Does Not Prevent an Immune Response to rtTA in Rats
D. Markusic, D. D. de Waart, J. Seppen
2010PLoS ONE20 citations Open access
Semantic Scholar
B cell focused transient immune suppression protocol for efficient AAV readministration to the liver
J. Rana, Roland W. Herzog, Maite Muñoz-Melero, Kentaro Yamada +8 more
2024Molecular Therapy: Methods & Clinical Development19 citations Open access
Semantic Scholar
Preferential Gene Transfer of Lentiviral Vectors to Liver-Derived Cells, Using a Hepatitis B Peptide Displayed on GP64
D. Markusic, A. Kanitz, R. Oude-Elferink, J. Seppen
2007Human Gene Therapy19 citations
Semantic Scholar
Alteration of viral lipid composition by expression of the phospholipid floppase ABCB4 reduces HIV vector infectivity
N. P. van Til, K. Heutinck, R. van der Rijt, C. Paulusma +4 more
2008Retrovirology18 citations Open access
Semantic Scholar
An Immune-Competent Murine Model to Study Elimination of AAV-Transduced Hepatocytes by Capsid-Specific CD8+ T Cells
Brett Palaschak, Damien Marsic, R. Herzog, S. Zolotukhin +1 more
2017Molecular Therapy: Methods & Clinical Development17 citations Open access
Semantic Scholar
Comprehensive Comparison of AAV Purification Methods: Iodixanol Gradient Centrifugation vs. Immuno-Affinity Chromatography
Anh K. Lam, P. Mulcrone, Dylan A. Frabutt, Junping Zhang +8 more
2023Advances in Cell and Gene Therapy16 citations Open access
Semantic Scholar
Tolerance Induction to Cytoplasmic \(\beta\)-galactosidase by Hepatic Aav Gene Transfer — Implications for Antigen Presentation and Immunotoxicity Tolerance Induction to Cytoplasmic B-galactosidase by Hepatic Aav Gene Transfer — Implications for Antigen Presentation and Immunotoxicity
C. Martino, A. T, Sushrusha Nayak, Brad E. Hoffman +7 more
16 citations
Semantic Scholar
Coagulation factor IX gene transfer to non-human primates using engineered AAV3 capsid and hepatic optimized expression cassette
Sandeep R. P. Kumar, Jun Xie, Shi Hu, Jihye Ko +9 more
2021Molecular Therapy: Methods & Clinical Development13 citations Open access
Semantic Scholar
Sensitive assay for mitochondrial DNA polymerase gamma.
R. Naviaux, D. Markusic, B. Barshop, W. Nyhan +1 more
1999Clinical Chemistry11 citations
Semantic Scholar
Inhibition of IFNAR-JAK signaling enhances tolerability and transgene expression of systemic non-viral DNA delivery
Sujata Senapati, Thais B. Bertolini, Michael Minnier, M. Yazicioglu +8 more
2025Molecular Therapy: Nucleic Acids10 citations Open access
Semantic Scholar
Editorial: Immunogenicity and toxicity of AAV gene therapy
Allison M. Bradbury, D. Markusic, Manish Muhuri, Li Ou
2023Frontiers in Immunology10 citations Open access
Semantic Scholar
Manipulating the microbiome to enhance oral tolerance in food allergy.
Miguel Gonzalez-Visiedo, M. Kulis, D. Markusic
2022Cellular Immunology10 citations Open access
Semantic Scholar
AAV vector biology in primates: finding the missing link?
R. Herzog, A. Davidoff, D. Markusic, A. Nathwani
2011Molecular Therapy7 citations Open access
Semantic Scholar
Doxycycline regulated lentiviral vectors.
D. Markusic, J. Seppen
2010Methods in molecular biology6 citations
Semantic Scholar
Viral Vector Based Immunotherapy for Peanut Allergy
Miguel Gonzalez-Visiedo, Roland W. Herzog, Maite Muñoz-Melero, S. Blessinger +3 more
2024Viruses5 citations Open access
Semantic Scholar
Adeno-Associated Virus D-Sequence-Mediated Suppression of Expression of a Human Major Histocompatibility Class II Gene: Implications in the Development of Adeno-Associated Virus Vectors for Modulating Humoral Immune Response
Hyung-Joo Kwon, Keyun Qing, S. Ponnazhagan, Xu-Shan Wang +4 more
2020Human Gene Therapy5 citations Open access
Semantic Scholar
Immunology of Gene and Cell Therapy.
D. Markusic, Ashley T. Martino, C. Porada, T. VandenDriessche
2020Molecular Therapy5 citations Open access
Semantic Scholar
Single-dose AAV vector gene immunotherapy to treat food allergy
Miguel Gonzalez-Visiedo, Xin Li, Maite Muñoz-Melero, M. Kulis +2 more
2022Molecular Therapy: Methods & Clinical Development3 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

R. Herzog×24
Invite
R. Herzog — researcher profile on SciRah
Brad E. Hoffman×9
Invite
Brad E. Hoffman — researcher profile on SciRah
Moanaro Biswas×7
Invite
Moanaro Biswas — researcher profile on SciRah
C. Terhorst×7
Invite
C. Terhorst — researcher profile on SciRah

×7

Invite

J. Seppen — researcher profile on SciRah

Ashley T. Martino×6

Invite

Ashley T. Martino — researcher profile on SciRah

I. Zolotukhin×6

Invite

I. Zolotukhin — researcher profile on SciRah

Sandeep R. P. Kumar×6

Invite

Sandeep R. P. Kumar — researcher profile on SciRah

Invite

R. Naviaux — researcher profile on SciRah

Brett Palaschak×6

Invite

Brett Palaschak — researcher profile on SciRah

Invite

R. Haas — researcher profile on SciRah

Sushrusha Nayak×5

Invite

Sushrusha Nayak — researcher profile on SciRah