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C. Kunne · SciRah

Researcher profile · Semantic Scholar

C. Kunne

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C. Kunne — researcher profile on SciRah

h-index: 28
Works: 57
Citations: 2,355

Most-cited papers

Atp8b1 deficiency in mice reduces resistance of the canalicular membrane to hydrophobic bile salts and impairs bile salt transport
C. Paulusma, A. Groen, C. Kunne, Ho-Mok Kam +11 more
2006Hepatology241 citations Open access
Semantic Scholar
Direct intestinal cholesterol secretion contributes significantly to total fecal neutral sterol excretion in mice.
A. van der Velde, C. Vrins, K. van den Oever, C. Kunne +3 more
2007Gastroenterology218 citations Open access
Semantic Scholar
Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides.
N. Zelcer, K. van de Wetering, R. de Waart, G. Scheffer +9 more
2006Journal of Hepatology189 citations Open access
Semantic Scholar
Complementary functions of the flippase ATP8B1 and the floppase ABCB4 in maintaining canalicular membrane integrity.
A. Groen, M. Romero, C. Kunne, Sarah J. Hoosdally +9 more
2011Gastroenterology119 citations
Semantic Scholar
Activity of the Bile Salt Export Pump (ABCB11) Is Critically Dependent on Canalicular Membrane Cholesterol Content
C. Paulusma, D. D. de Waart, C. Kunne, Kam S. Mok +1 more
2009Journal of Biological Chemistry118 citations Open access
Semantic Scholar
Altered disposition of acetaminophen in mice with a disruption of the Mrp3 gene
J. Manautou, D. D. de Waart, C. Kunne, N. Zelcer +3 more
2005Hepatology114 citations Open access
Semantic Scholar
A mouse genetic model for familial cholestasis caused by ATP8B1 mutations reveals perturbed bile salt homeostasis but no impairment in bile secretion.
Ludmila Pawlikowska, A. Groen, E. Eppens, C. Kunne +7 more
2004Human Molecular Genetics108 citations
Semantic Scholar
Hepatic Transport Mechanisms of Cholyl-l-Lysyl-Fluorescein
D. D. de Waart, S. Häusler, M. Vlaming, C. Kunne +4 more
2010Journal of Pharmacology and Experimental Therapeutics98 citations Open access
Semantic Scholar
Adeno-associated virus vector serotypes mediate sustained correction of bilirubin UDP glucuronosyltransferase deficiency in rats.
J. Seppen, C. Bakker, Berry de Jong, C. Kunne +5 more
2006Molecular Therapy89 citations Open access
Semantic Scholar
Lipotoxicity and steatohepatitis in an overfed mouse model for non-alcoholic fatty liver disease.
I. Gaemers, Jan M. Stallen, C. Kunne, C. Wallner +3 more
2011Biochimica et Biophysica Acta88 citations Open access
Semantic Scholar
Glutamine Synthetase in Muscle Is Required for Glutamine Production during Fasting and Extrahepatic Ammonia Detoxification*
Youji He, T. Hakvoort, S. Köhler, J. Vermeulen +11 more
2010Journal of Biological Chemistry78 citations Open access
Semantic Scholar
Cyclosporin A Induces Peritoneal Fibrosis and Angiogenesis during Chronic Peritoneal Exposure to a Glucose-Based, Lactate-Buffered Dialysis Solution in the Rat
R. van Westrhenen, J. Aten, Najat Hajji, O. D. de Boer +3 more
2007Blood Purification70 citations
Semantic Scholar
The mechanism of ABCG5/ABCG8 in biliary cholesterol secretion in mice1 Published, JLR Papers in Press, June 1, 2006.
A. Kosters, C. Kunne, Norbert A Looije, Shailendra B. Patel +2 more
2006Journal of Lipid Research63 citations Open access
Semantic Scholar
Enhanced Glucocorticoid Feedback Inhibition of Hypothalamo-Pituitary-Adrenal Responses to Stress in Adult Rats Neonatally Treated with Dexamethasone
P. Kamphuis, J. Bakker, M. Broekhoven, C. Kunne +5 more
2002Neuroendocrinology61 citations
Semantic Scholar
Abcg5/8 independent biliary cholesterol excretion in Atp8b1-deficient mice.
A. Groen, C. Kunne, G. Jongsma, K. van den Oever +6 more
2008Gastroenterology59 citations
Semantic Scholar
Kupffer cells and not liver sinusoidal endothelial cells prevent lentiviral transduction of hepatocytes.
N. P. van Til, D. Markusic, R. van der Rijt, C. Kunne +5 more
2005Molecular Therapy56 citations Open access
Semantic Scholar
Diosgenin‐induced biliary cholesterol secretion in mice requires Abcg8
A. Kosters, Raoul J. J. M. Frijters, C. Kunne, E. Vink +5 more
2005Hepatology52 citations Open access
Semantic Scholar
Ezetimibe stimulates faecal neutral sterol excretion depending on abcg8 function in mice
L. Jakulj, M. N. Vissers, C. van Roomen, Jelske N. van der Veen +5 more
2010FEBS Letters51 citations Open access
Semantic Scholar
Immune response to lentiviral bilirubin UDP-glucuronosyltransferase gene transfer in fetal and neonatal rats
J. Seppen, N. P. van Til, R. van der Rijt, Johan K. Hiralall +2 more
2006Gene Therapy46 citations Open access
Semantic Scholar
Multidrug resistance associated protein 2 mediates transport of prostaglandin E2
D. D. de Waart, C. Paulusma, C. Kunne, R. O. Oude Elferink
2006Liver international (Print)45 citations
Semantic Scholar
Inefficient chronic activation of parietal cells in Ae2a,b(-/-) mice.
S. Recalde, F. Muruzábal, Norbert A Looije, C. Kunne +8 more
2006American Journal of Pathology40 citations Open access
Semantic Scholar
FXR-dependent reduction of hepatic steatosis in a bile salt deficient mouse model.
C. Kunne, A. Acco, Suzanne Duijst, D. D. de Waart +3 more
2014Biochimica et Biophysica Acta38 citations Open access
Semantic Scholar
Complex Pharmacokinetic Behavior of Ezetimibe Depends on Abcc2, Abcc3, and Abcg2
D. D. de Waart, M. Vlaming, C. Kunne, A. Schinkel +1 more
2009Drug Metabolism And Disposition38 citations
Semantic Scholar
Mycophenolate Mofetil Impairs Transduction of Single-Stranded Adeno-Associated Viral Vectors
Paula S. Montenegro-Miranda, L. ten Bloemendaal, C. Kunne, D. D. de Waart +1 more
2011Human Gene Therapy36 citations
Semantic Scholar
A Pyruvate-Buffered Dialysis Fluid Induces Less Peritoneal Angiogenesis and Fibrosis than a Conventional Solution
R. van Westrhenen, M. M. Zweers, C. Kunne, D. D. de Waart +2 more
2008Peritoneal Dialysis International35 citations Open access
Semantic Scholar
Oral Availability of Cefadroxil Depends on ABCC3 and ABCC4
D. D. de Waart, K. van de Wetering, C. Kunne, Suzanne Duijst +2 more
2012Drug Metabolism And Disposition34 citations
Semantic Scholar
Defective bile salt biosynthesis and hydroxylation in mice with reduced cytochrome P450 activity
C. Kunne, A. Acco, S. Hohenester, Suzanne Duijst +3 more
2013Hepatology31 citations Open access
Semantic Scholar
The role of epoxidation and electrophile-responsive element-regulated gene transcription in the potentially beneficial and harmful effects of the coffee components cafestol and kahweol.
S. T. J. van Cruchten, L. D. de Haan, P. Mulder, C. Kunne +4 more
2010Journal of Nutritional Biochemistry30 citations Open access
Semantic Scholar
Intestinal bile salt absorption in Atp8b1 deficient mice.
A. Groen, C. Kunne, C. Paulusma, W. Kramer +3 more
2007Journal of Hepatology25 citations
Semantic Scholar
Inhibition of miR-142-5P ameliorates disease in mouse models of experimental colitis
N. Duijvis, P. Moerland, C. Kunne, Monique M W Slaman +6 more
2017PLoS ONE24 citations Open access
Semantic Scholar
Actual Usage and Quality of Experimental Colitis Models in Preclinical Efficacy Testing: A Scoping Review
Sophia B Zeeff, C. Kunne, G. Bouma, R. de Vries +1 more
2016Inflammatory Bowel Diseases18 citations Open access
Semantic Scholar
Increased serum concentrations of secondary bile salts during cholate feeding are due to coprophagy. A study with wild-type and Atp8b1-deficient mice.
A. Groen, C. Kunne, R. O. Oude Elferink
2006Molecular Pharmaceutics15 citations
Semantic Scholar
Bone marrow-derived multidrug resistance protein ABCB4 protects against atherosclerotic lesion development in LDL receptor knockout mice.
M. Pennings, R. B. Hildebrand, D. Ye, C. Kunne +3 more
2007Cardiovascular Research14 citations Open access
Semantic Scholar
The mechanism of ABCG 5 / ABCG 8 in biliary cholesterol secretion in mice 1
A. Kosters, C. Kunne, Norbert A Looije, Shailendra B. Patel +2 more
20069 citations
Semantic Scholar
Hepatic cytochrome p 450 deficiency in mouse models for intrahepatic cholestasis predispose to bile salt induced cholestasis
C. Kunne
20135 citations
Semantic Scholar
Hepatic cytochrome P450 deficiency in mouse models for intrahepatic cholestasis predispose to bile salt-induced cholestasis
C. Kunne, M. de Graaff, Suzanne Duijst, D. D. de Waart +2 more
2014Laboratory Investigation2 citations Open access
Semantic Scholar
TRANS INTESTINAL CHOLESTEROL EFFLUX PATHWAY IS REDUCED IN APOE KNOCKOUT MICE
C. Vrins, A. van der Velde, K. van den Oever, C. Kunne +3 more
20081 citations
Semantic Scholar
Subject Index Vol. 25, 2007
A. Ramunni, P. Brescia, D. Quaranta, M. Plantamura +109 more
2007Blood Purification1 citations Open access
Semantic Scholar
872. AAV 1 and 8 Have Higher Efficacy Than AAV 2 in Correction of Hyperbilirubinemia in the Gunn Rat, the Animal Model for the Metabolic Liver Dissorder Crigler-Najjar Syndrome
P. Bosma, Berry de Jong, Norbert A Looije, C. Kunne +2 more
20041 citations Open access
Semantic Scholar
Mouse models of cholestatic liver disease: PFIC revisited
C. Kunne, M. de Graaff, Suzanne Duijst, D. D. de Waart +2 more
20130 citations
Semantic Scholar
Mouse models of cholestatic liver disease: PFIC revisited
C. Kunne
20130 citations
Semantic Scholar
Neural control of hepatic lipid metabolism : A ( patho ) physiological perspective
C. Kunne, R. O. Oude Elferink, A. Kalsbeek
20130 citations
Semantic Scholar
Microsoft Word-11741847-file00
D. D. de Waart, S. Häusler, M. Vlaming, C. Kunne +5 more
20100 citations
Semantic Scholar
Membrane asymmetry and the regulation of bile formation
R. O. Oude Elferink, A. Groen, Kam S. Mok, C. Kunne +4 more
20090 citations
Semantic Scholar
ATP8B1, a phosphatidylserine flippase deficient in inherited intrahepatic cholestasis
C. Paulusma, A. Groen, C. Kunne, Kam S. Mok +4 more
20090 citations
Semantic Scholar
The molecular mechanism of Atp 8 b 1-deficiency
A. Groen, C. Kunne, G. Jongsma, K. van den Oever +6 more
20090 citations
Semantic Scholar
Bone marrow derived multidrug restistance protein ABCB4 protects against atherosclerotic lesion development in LDL receptor knock out mice
M. Pennings, R. B. Hildebrand, D. Ye, C. Kunne +4 more
20080 citations
Semantic Scholar
Chapterr 8 PYRUVATE-BUFFEREDD DIALYSATE FLUIDS INDUCE LESS PERITONEALL ANGIOGENESIS AND FIBROSIS THAN CONVENTIONAL SOLUTIONS
R. van Westrhenen, M. M. Zweers, C. Kunne, D. D. de Waart +2 more
20080 citations
Semantic Scholar
Chapterr 6 LISINOPRILL IN A CHRONIC PERITONEAL EXPOSURE MODEL INN THE RAT
R. van Westrhenen, C. Dragt, C. Kunne, J. +2 more
20080 citations
Semantic Scholar
Understanding and preventing the peritoneal damage caused by conventional dialysis solutions
R. van Westrhenen, J. Aten, Najat Hajji, O. D. de Boer +3 more
20080 citations
Semantic Scholar

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