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S. Cole · SciRah

Researcher profile · Semantic Scholar

S. Cole

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S. Cole — researcher profile on SciRah

h-index: 104
Works: 409
Citations: 47K

Most-cited papers

Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1.
R. Wassermann, M. F. Gulen, C. Sala, Sonia Garcia Perin +7 more
2015Cell Host and Microbe392 citations Open access
Semantic Scholar
Red squirrels in the British Isles are infected with leprosy bacilli
C. Avanzi, J. del-Pozo, Andrej Benjak, K. Stevenson +14 more
2016Science169 citations Open access
Semantic Scholar
Lansoprazole is an antituberculous prodrug targeting cytochrome bc1
J. Rybniker, Anthony Vocat, C. Sala, Philippe Busso +3 more
2015Nature Communications158 citations Open access
Semantic Scholar
Insight into the evolution and origin of leprosy bacilli from the genome sequence of Mycobacterium lepromatosis
Pushpendra Singh, Andrej Benjak, V. Schuenemann, A. Herbig +6 more
2015Proceedings of the National Academy of Sciences of the United States of America152 citations Open access
Semantic Scholar
DprE1 Is a Vulnerable Tuberculosis Drug Target Due to Its Cell Wall Localization.
M. Brecik, Ivana Centárová, R. Mukherjee, Gaëlle S. Kolly +10 more
2015ACS Chemical Biology152 citations Open access
Semantic Scholar
Zoonotic Leprosy in the Southeastern United States
Rahul Sharma, Pushpendra Singh, W. J. Loughry, J. Lockhart +7 more
2015Emerging Infectious Diseases134 citations Open access
Semantic Scholar
2-Carboxyquinoxalines kill mycobacterium tuberculosis through noncovalent inhibition of DprE1.
J. Neres, R. Hartkoorn, L. Chiarelli, Ramakrishna Gadupudi +25 more
2015ACS Chemical Biology131 citations Open access
Semantic Scholar
Mode of Action of Clofazimine and Combination Therapy with Benzothiazinones against Mycobacterium tuberculosis
Benoit Lechartier, S. Cole
2015Antimicrobial Agents and Chemotherapy127 citations Open access
Semantic Scholar
Ancient genomes reveal a high diversity of Mycobacterium leprae in medieval Europe
V. Schuenemann, C. Avanzi, B. Krause-Kyora, Alexander Seitz +26 more
2018PLoS Pathogens124 citations Open access
Semantic Scholar
Phylogenomics and antimicrobial resistance of the leprosy bacillus Mycobacterium leprae
Andrej Benjak, C. Avanzi, Pushpendra Singh, C. Loiseau +39 more
2018Nature Communications109 citations Open access
Semantic Scholar
Essentiality of mmpL3 and impact of its silencing on Mycobacterium tuberculosis gene expression
Giulia Degiacomi, Andrej Benjak, Jan Madacki, Francesca Boldrin +5 more
2017Scientific Reports105 citations Open access
Semantic Scholar
Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis.
Galina Karabanovich, Júlia Zemanová, T. Smutny, R. Székely +15 more
2016Journal of Medicinal Chemistry103 citations Open access
Semantic Scholar
Anticytolytic screen identifies inhibitors of mycobacterial virulence protein secretion.
J. Rybniker, Jeffrey M. Chen, C. Sala, R. Hartkoorn +11 more
2014Cell Host and Microbe95 citations Open access
Semantic Scholar
The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis
Vinayak Singh, S. Donini, A. Pacitto, C. Sala +18 more
2016ACS Infectious Diseases94 citations Open access
Semantic Scholar
Discovery and Biosynthesis of Gladiolin: A Burkholderia gladioli Antibiotic with Promising Activity against Mycobacterium tuberculosis.
Li-Jiang Song, M. Jenner, J. Masschelein, Cerith Jones +14 more
2017Journal of the American Chemical Society91 citations Open access
Semantic Scholar
Evidence of zoonotic leprosy in Pará, Brazilian Amazon, and risks associated with human contact or consumption of armadillos
M. B. da Silva, J. Portela, Wei Li, M. Jackson +14 more
2018PLoS Neglected Tropical Diseases85 citations Open access
Semantic Scholar
Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG
G. Mori, L. Chiarelli, M. Esposito, V. Makarov +25 more
2015Chemistry and Biology85 citations Open access
Semantic Scholar
Leprosy in wild chimpanzees
K. Hockings, B. Mubemba, C. Avanzi, Kamilla Pléh +29 more
2020Nature78 citations Open access
Semantic Scholar
Transcription facilitated genome-wide recruitment of topoisomerase I and DNA gyrase
Wareed Ahmed, C. Sala, Shubhada R. Hegde, R. Jha +2 more
2017PLoS Genetics68 citations Open access
Semantic Scholar
Structural studies of Mycobacterium tuberculosis DprE1 interacting with its inhibitors.
J. Piton, C. Foo, S. Cole
2017Drug Discovery Today67 citations Open access
Semantic Scholar
The 8-Pyrrole-Benzothiazinones Are Noncovalent Inhibitors of DprE1 from Mycobacterium tuberculosis
V. Makarov, J. Neres, R. Hartkoorn, O. Ryabova +9 more
2015Antimicrobial Agents and Chemotherapy66 citations Open access
Semantic Scholar
Arylvinylpiperazine Amides, a New Class of Potent Inhibitors Targeting QcrB of Mycobacterium tuberculosis
C. Foo, Andréanne Lupien, M. Kienle, Anthony Vocat +8 more
2018mBio58 citations Open access
Semantic Scholar
Inhibiting Mycobacterium tuberculosis within and without
S. Cole
2016Philosophical Transactions of the Royal Society B: Biological Sciences57 citations Open access
Semantic Scholar
Optimized Background Regimen for Treatment of Active Tuberculosis with the Next-Generation Benzothiazinone Macozinone (PBTZ169)
Andréanne Lupien, Anthony Vocat, C. Foo, Emilyne Blattes +3 more
2018Antimicrobial Agents and Chemotherapy56 citations Open access
Semantic Scholar
Discovery of benzothiazoles as antimycobacterial agents: Synthesis, structure-activity relationships and binding studies with Mycobacterium tuberculosis decaprenylphosphoryl-β-D-ribose 2'-oxidase.
S. Landge, Amrita B Mullick, Kavitha Nagalapur, J. Neres +22 more
2015Bioorganic & Medicinal Chemistry52 citations Open access
Semantic Scholar
Structure of EspB, a secreted substrate of the ESX-1 secretion system of Mycobacterium tuberculosis
N. Korotkova, J. Piton, J. M. Wagner, Stefanie Boy-Röttger +5 more
2015Journal of Structural Biology50 citations Open access
Semantic Scholar
Whole genome sequencing distinguishes between relapse and reinfection in recurrent leprosy cases
M. M. Stefani, C. Avanzi, S. Bührer-Sékula, Andrej Benjak +19 more
2017PLoS Neglected Tropical Diseases49 citations Open access
Semantic Scholar
A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK
L. Chiarelli, G. Mori, B. Orena, M. Esposito +19 more
2018Scientific Reports42 citations Open access
Semantic Scholar
Structure-Based Drug Design and Characterization of Sulfonyl-Piperazine Benzothiazinone Inhibitors of DprE1 from Mycobacterium tuberculosis
J. Piton, Anthony Vocat, Andréanne Lupien, C. Foo +3 more
2018Antimicrobial Agents and Chemotherapy41 citations Open access
Semantic Scholar
Comparison of target enrichment strategies for ancient pathogen DNA
Anja Furtwängler, Judith Neukamm, Lisa Böhme, Ella Reiter +10 more
2020bioRxiv39 citations Open access
Semantic Scholar
Mycobacterium leprae diversity and population dynamics in medieval Europe from novel ancient genomes
S. Pfrengle, Judith Neukamm, Meriam Guellil, Marcel Keller +35 more
2021BMC Biology38 citations Open access
Semantic Scholar
Characterization of DprE1-Mediated Benzothiazinone Resistance in Mycobacterium tuberculosis
C. Foo, Benoit Lechartier, Gaëlle S. Kolly, Stefanie Boy-Röttger +6 more
2016Antimicrobial Agents and Chemotherapy38 citations Open access
Semantic Scholar
New 2-Ethylthio-4-methylaminoquinazoline derivatives inhibiting two subunits of cytochrome bc1 in Mycobacterium tuberculosis
Andréanne Lupien, C. Foo, Svetlana Savina, Anthony Vocat +8 more
2020PLoS Pathogens37 citations Open access
Semantic Scholar
Micrococcin P1 - A bactericidal thiopeptide active against Mycobacterium tuberculosis.
Giulia Degiacomi, Yoann Personne, Guillaume Mondésert, X. Ge +16 more
2016Tuberculosis36 citations Open access
Semantic Scholar
Genomic Characterization of Mycobacterium leprae to Explore Transmission Patterns Identifies New Subtype in Bangladesh
M. Tió-Coma, C. Avanzi, Els M. Verhard, Louise Pierneef +9 more
2020Frontiers in Microbiology34 citations Open access
Semantic Scholar
EspL is essential for virulence and stabilizes EspE, EspF and EspH levels in Mycobacterium tuberculosis
C. Sala, N. Odermatt, Paloma Soler-Arnedo, M. F. Gulen +3 more
2018PLoS Pathogens34 citations Open access
Semantic Scholar
Lead selection and characterization of antitubercular compounds using the Nested Chemical Library.
Anna Sipos, J. Pató, R. Székely, R. Hartkoorn +13 more
2015Tuberculosis32 citations Open access
Semantic Scholar
Bioluminescence for Assessing Drug Potency against Nonreplicating Mycobacterium tuberculosis
Anthony Vocat, R. Hartkoorn, Benoit Lechartier, Ming Zhang +3 more
2015Antimicrobial Agents and Chemotherapy32 citations Open access
Semantic Scholar
Whole cell screen based identification of spiropiperidines with potent antitubercular properties.
S. Tantry, Giulia Degiacomi, Sreevalli Sharma, L. K. Jena +23 more
2015Bioorganic & Medicinal Chemistry Letters32 citations Open access
Semantic Scholar
Transmission of Drug-Resistant Leprosy in Guinea-Conakry Detected Using Molecular Epidemiological Approaches.
C. Avanzi, Philippe Busso, Andrej Benjak, C. Loiseau +11 more
2016Clinical Infectious Diseases31 citations Open access
Semantic Scholar
British Red Squirrels Remain the Only Known Wild Rodent Host for Leprosy Bacilli
Anna-Katarina Schilling, C. Avanzi, R. Ulrich, Philippe Busso +15 more
2019Frontiers in Veterinary Science30 citations Open access
Semantic Scholar
NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans
M. Gengenbacher, María A. Duque-Correa, P. Kaiser, S. Schuerer +9 more
2017Scientific Reports30 citations Open access
Semantic Scholar
GtrA Protein Rv3789 Is Required for Arabinosylation of Arabinogalactan in Mycobacterium tuberculosis
Gaëlle S. Kolly, R. Mukherjee, Emöke Kilacsková, L. Abriata +6 more
2015Journal of Bacteriology28 citations Open access
Semantic Scholar
Essential Nucleoid Associated Protein mIHF (Rv1388) Controls Virulence and Housekeeping Genes in Mycobacterium tuberculosis
N. Odermatt, C. Sala, Andrej Benjak, S. Cole
2018Scientific Reports27 citations Open access
Semantic Scholar
High resolution CryoEM structure of the ring-shaped virulence factor EspB from Mycobacterium tuberculosis
J. Piton, F. Pojer, S. Wakatsuki, C. Gati +1 more
2020Journal of Structural Biology: X25 citations Open access
Semantic Scholar
Population Genomics of Mycobacterium leprae Reveals a New Genotype in Madagascar and the Comoros
C. Avanzi, E. Lécorché, F. Rakotomalala, Andrej Benjak +24 more
2020Frontiers in Microbiology23 citations Open access
Semantic Scholar
Mycobacterium tuberculosis EspK Has Active but Distinct Roles in the Secretion of EsxA and EspB
Ze-Long Lim, K. Drever, Neeraj Dhar, S. Cole +1 more
2022Journal of Bacteriology22 citations Open access
Semantic Scholar
Evaluation of Auramine O staining and conventional PCR for leprosy diagnosis: A comparative cross-sectional study from Ethiopia
Selfu Girma, C. Avanzi, K. Bobosha, Kassu Desta +7 more
2018PLoS Neglected Tropical Diseases22 citations Open access
Semantic Scholar
Fluorescent Benzothiazinone Analogues Efficiently and Selectively Label Dpre1 in Mycobacteria and Actinobacteria.
Raphael Sommer, J. Neres, J. Piton, Neeraj Dhar +8 more
2018ACS Chemical Biology21 citations Open access
Semantic Scholar
Total Synthesis of Ripostatin B and Structure-Activity Relationship Studies on Ripostatin Analogs.
F. Glaus, Darija Dedić, Priyanka Tare, V. Nagaraja +7 more
2018Journal of Organic Chemistry19 citations Open access
Semantic Scholar

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