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Katarína Mikušová · SciRah

Researcher profile · Semantic Scholar

Katarína Mikušová

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Katarína Mikušová — researcher profile on SciRah

h-index: 36
Works: 85
Citations: 6,187

Most-cited papers

Sequences Human Induced Pluripotent Stem Cells Free of Vector and Transgene
G. Manina, Katarína Mikušová, U. Möllmann, O. Ryabova +30 more
20121,085 citations
Semantic Scholar
Benzothiazinones Kill Mycobacterium tuberculosis by Blocking Arabinan Synthesis
V. Makarov, G. Manina, Katarína Mikušová, U. Möllmann +33 more
2009Science733 citations Open access
Semantic Scholar
The embAB genes of Mycobacterium avium encode an arabinosyl transferase involved in cell wall arabinan biosynthesis that is the target for the antimycobacterial drug ethambutol.
Aimee E. Belanger, G. Besra, Michael E. Ford, Katarína Mikušová +3 more
1996Proceedings of the National Academy of Sciences of the United States of America485 citations Open access
Semantic Scholar
Biogenesis of the mycobacterial cell wall and the site of action of ethambutol
Katarína Mikušová, R. Slayden, G. Besra, P. Brennan
1995Antimicrobial Agents and Chemotherapy291 citations Open access
Semantic Scholar
University of Birmingham Identification of a small molecule with activity against drug-resistant and persistent tuberculosis
Feng Sambandan, Dhinakaran Halder, R.-A. Wang, Jianing Batt +30 more
2013211 citations
Semantic Scholar
Decaprenylphosphoryl Arabinofuranose, the Donor of the d-Arabinofuranosyl Residues of Mycobacterial Arabinan, Is Formed via a Two-Step Epimerization of Decaprenylphosphoryl Ribose
Katarína Mikušová, Hairong Huang, T. Yagi, M. Holsters +6 more
2005Journal of Bacteriology207 citations Open access
Semantic Scholar
Benzothiazinones are suicide inhibitors of mycobacterial decaprenylphosphoryl-β-D-ribofuranose 2'-oxidase DprE1.
Claudia Trefzer, Henrieta Škovierová, S. Buroni, Adela Bobovská +9 more
2012Journal of the American Chemical Society175 citations Open access
Semantic Scholar
Definition of the First Mannosylation Step in Phosphatidylinositol Mannoside Synthesis
J. Korduláková, M. Gilleron, Katarína Mikušová, G. Puzo +3 more
2002Journal of Biological Chemistry173 citations Open access
Semantic Scholar
Biosynthesis of the Linkage Region of the Mycobacterial Cell Wall (*)
Katarína Mikušová, M. Mikuš, G. Besra, I. Hancock +1 more
1996Journal of Biological Chemistry167 citations Open access
Semantic Scholar
DprE1 Is a Vulnerable Tuberculosis Drug Target Due to Its Cell Wall Localization.
M. Brecik, Ivana Centárová, R. Mukherjee, Gaëlle S. Kolly +10 more
2015ACS Chemical Biology152 citations Open access
Semantic Scholar
Recognition of multiple effects of ethambutol on metabolism of mycobacterial cell envelope
L. Deng, Katarína Mikušová, K. G. Robuck, Michael S. Scherman +2 more
1995Antimicrobial Agents and Chemotherapy140 citations Open access
Semantic Scholar
Molecular Recognition and Interfacial Catalysis by the Essential Phosphatidylinositol Mannosyltransferase PimA from Mycobacteria*
M. Guerin, J. Korduláková, F. Schaeffer, Zuzana Svetlíková +6 more
2007Journal of Biological Chemistry129 citations Open access
Semantic Scholar
Synthesis of the Arabinose Donor .beta.-D-Arabinofuranosyl-1-monophosphoryldecaprenol, Development of a Basic Arabinosyl-Transferase Assay, and Identification of Ethambutol as an Arabinosyl Transferase Inhibitor
R. Lee, Katarína Mikušová, P. Brennan, G. Besra
1995123 citations
Semantic Scholar
Identification of the Required Acyltransferase Step in the Biosynthesis of the Phosphatidylinositol Mannosides of Mycobacterium Species*
J. Korduláková, M. Gilleron, G. Puzo, P. Brennan +3 more
2003Journal of Biological Chemistry107 citations Open access
Semantic Scholar
Biosynthesis of the Galactan Component of the Mycobacterial Cell Wall*
Katarína Mikušová, T. Yagi, Richard J. Stern, M. Mcneil +3 more
2000Journal of Biological Chemistry107 citations Open access
Semantic Scholar
Truncated Structural Variants of Lipoarabinomannan in Ethambutol Drug-resistant Strains of Mycobacterium smegmatis
K. Khoo, E. Douglas, P. Azadi, J. M. Inamine +4 more
1996Journal of Biological Chemistry107 citations Open access
Semantic Scholar
Development of 3,5-Dinitrobenzylsulfanyl-1,3,4-oxadiazoles and Thiadiazoles as Selective Antitubercular Agents Active Against Replicating and Nonreplicating Mycobacterium tuberculosis.
Galina Karabanovich, Júlia Zemanová, T. Smutny, R. Székely +15 more
2016Journal of Medicinal Chemistry103 citations Open access
Semantic Scholar
Galactosyl Transferases in Mycobacterial Cell Wall Synthesis
Martina Beláňová, Petronela Dianišková, P. Brennan, Gladys C. Completo +3 more
2007Journal of Bacteriology100 citations Open access
Semantic Scholar
The complex mechanism of antimycobacterial action of 5-fluorouracil.
Vinayak Singh, M. Brecik, R. Mukherjee, Joanna C. Evans +7 more
2015Chemistry and Biology99 citations Open access
Semantic Scholar
Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG
G. Mori, L. Chiarelli, M. Esposito, V. Makarov +25 more
2015Chemistry and Biology85 citations Open access
Semantic Scholar
Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance
G. Manina, M. Bellinzoni, M. Pasca, J. Neres +19 more
2010Molecular Microbiology79 citations Open access
Semantic Scholar
Identification of a Novel Galactosyl Transferase Involved in Biosynthesis of the Mycobacterial Cell Wall
Katarína Mikušová, Martina Beláňová, J. Korduláková, K. Honda +4 more
2006Journal of Bacteriology69 citations Open access
Semantic Scholar
The 8-Pyrrole-Benzothiazinones Are Noncovalent Inhibitors of DprE1 from Mycobacterium tuberculosis
V. Makarov, J. Neres, R. Hartkoorn, O. Ryabova +9 more
2015Antimicrobial Agents and Chemotherapy66 citations Open access
Semantic Scholar
Assembling of the Mycobacterium tuberculosis Cell Wall Core*
A. Grzegorzewicz, Célia de Sousa-d'Auria, M. Mcneil, E. Huc-Claustre +14 more
2016Journal of Biological Chemistry63 citations Open access
Semantic Scholar
Development of Macozinone for TB treatment: An Update
V. Makarov, Katarína Mikušová
2020Applied Sciences58 citations Open access
Semantic Scholar
DprE1--from the discovery to the promising tuberculosis drug target.
Katarína Mikušová, V. Makarov, J. Neres
2013Current pharmaceutical design57 citations Open access
Semantic Scholar
Design, Syntheses, and Anti-TB Activity of 1,3-Benzothiazinone Azide and Click Chemistry Products Inspired by BTZ043.
R. Tiwari, Patricia A. Miller, L. Chiarelli, G. Mori +7 more
2016ACS Medicinal Chemistry Letters56 citations Open access
Semantic Scholar
Drugging the Folate Pathway in Mycobacterium Tuberculosis: The Role of Multi-Targeting Agents
B. Hajian, Eric Scocchera, Carolyn Shoen, J. Krucinska +8 more
2019Cell Chemical Biology55 citations Open access
Semantic Scholar
Fragment-Based Design of Mycobacterium tuberculosis InhA Inhibitors
M. Sabbah, Vítor Mendes, Robert G. Vistal, David M. G. Dias +6 more
2019Journal of Medicinal Chemistry46 citations Open access
Semantic Scholar
Synthetic UDP-furanoses as potent inhibitors of mycobacterial galactan biogenesis
Pauline Peltier, Martina Beláňová, Petronela Dianišková, Ruokun Zhou +9 more
2010Chemistry and Biology46 citations Open access
Semantic Scholar
Development of 3,5-Dinitrophenyl-Containing 1,2,4-Triazoles and their Trifluoromethyl Analogues as Highly Efficient Antitubercular Agents Inhibiting Decaprenylphosphoryl-β-D-ribofuranose 2'-Oxidase.
Galina Karabanovich, J. Dušek, Karin Savková, O. Pavliš +16 more
2019Journal of Medicinal Chemistry44 citations
Semantic Scholar
The Phosphatidyl-myo-Inositol Mannosyltransferase PimA Is Essential for Mycobacterium tuberculosis Growth In Vitro and In Vivo
Francesca Boldrin, M. Ventura, Giulia Degiacomi, S. Ravishankar +15 more
2014Journal of Bacteriology43 citations Open access
Semantic Scholar
A multitarget approach to drug discovery inhibiting Mycobacterium tuberculosis PyrG and PanK
L. Chiarelli, G. Mori, B. Orena, M. Esposito +19 more
2018Scientific Reports42 citations Open access
Semantic Scholar
Biosynthetic Origin of the Galactosamine Substituent of Arabinogalactan in Mycobacterium tuberculosis*
Henrieta Škovierová, G. Larrouy-Maumus, H. Pham, Martina Beláňová +9 more
2010Journal of Biological Chemistry42 citations Open access
Semantic Scholar
A Phenotypic Based Target Screening Approach Delivers New Antitubercular CTP Synthetase Inhibitors.
M. Esposito, Sára Szádocka, Giulia Degiacomi, B. Orena +15 more
2017ACS Infectious Diseases38 citations Open access
Semantic Scholar
New lipophilic isoniazid derivatives and their 1,3,4-oxadiazole analogues: Synthesis, antimycobacterial activity and investigation of their mechanism of action.
Rudolf Vosátka, M. Krátký, Markéta Švarcová, J. Janoušek +7 more
2018European journal of medicinal chemistry36 citations
Semantic Scholar
Polymerization of Mycobacterial Arabinogalactan and Ligation to Peptidoglycan*
T. Yagi, S. Mahapatra, Katarína Mikušová, D. Crick +1 more
2003Journal of Biological Chemistry36 citations Open access
Semantic Scholar
Synthesis of 1,2,3-triazolo-linked octyl (1→6)-α-D-oligomannosides and their evaluation in mycobacterial mannosyltransferase assay.
M. Poláková, Martina Beláňová, Katarína Mikušová, E. Lattová +1 more
2011Bioconjugate chemistry33 citations
Semantic Scholar
Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA
D. Albesa-Jové, Zuzana Svetlíková, M. Tersa, E. Sancho-Vaello +10 more
2016Nature Communications32 citations Open access
Semantic Scholar
Lead selection and characterization of antitubercular compounds using the Nested Chemical Library.
Anna Sipos, J. Pató, R. Székely, R. Hartkoorn +13 more
2015Tuberculosis32 citations Open access
Semantic Scholar
N-Acetylglucosamine-1-Phosphate Transferase, WecA, as a Validated Drug Target in Mycobacterium tuberculosis
Stanislav Huszár, Vinayak Singh, Alica Polčicová, P. Baráth +6 more
2017Antimicrobial Agents and Chemotherapy29 citations Open access
Semantic Scholar
A Small Multidrug Resistance-like Transporter Involved in the Arabinosylation of Arabinogalactan and Lipoarabinomannan in Mycobacteria*
G. Larrouy-Maumus, Henrieta Škovierová, R. Dhouib, S. K. Angala +12 more
2012Journal of Biological Chemistry29 citations Open access
Semantic Scholar
Design, synthesis and evaluation of covalent inhibitors of DprE1 as antitubercular agents.
Ling-Hsuan Liu, Chengcheng Kong, M. Fumagalli, Karin Savková +8 more
2020European journal of medicinal chemistry28 citations Open access
Semantic Scholar
GtrA Protein Rv3789 Is Required for Arabinosylation of Arabinogalactan in Mycobacterium tuberculosis
Gaëlle S. Kolly, R. Mukherjee, Emöke Kilacsková, L. Abriata +6 more
2015Journal of Bacteriology28 citations Open access
Semantic Scholar
Learning from the past for TB drug discovery in the future
Katarína Mikušová, S. Ekins
2016Drug Discovery Today27 citations Open access
Semantic Scholar
Identification of aminopyrimidine‐sulfonamides as potent modulators of Wag31‐mediated cell elongation in mycobacteria
Vinayak Singh, Neeraj Dhar, J. Pató, Gaëlle S. Kolly +27 more
2017Molecular Microbiology25 citations Open access
Semantic Scholar
Biosynthesis of Galactan in Mycobacterium tuberculosis as a Viable TB Drug Target?
Zuzana Konyariková, Karin Savková, S. Kozmon, Katarína Mikušová
2020Antibiotics24 citations Open access
Semantic Scholar
Synthesis of alkyl and cycloalkyl alpha-d-mannopyranosides and derivatives thereof and their evaluation in the mycobacterial mannosyltransferase assay.
M. Poláková, Martina Beláňová, L. Petruš, Katarína Mikušová
2010Carbohydrate Research24 citations
Semantic Scholar
Investigation of ABC transporter from mycobacterial arabinogalactan biosynthetic cluster
Petronela Dianišková, J. Korduláková, Henrieta Škovierová, D. Kaur +3 more
2011General Physiology and Biophysics22 citations Open access
Semantic Scholar
An ethA-ethR-Deficient Mycobacterium bovis BCG Mutant Displays Increased Adherence to Mammalian Cells and Greater Persistence In Vivo, Which Correlate with Altered Mycolic Acid Composition
M. Ang, Zarina Zainul Rahim Siti, Guang-Hou Shui, Petronela Dianišková +11 more
2014Infection and Immunity19 citations Open access
Semantic Scholar

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