Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

K. Okkenhaug · SciRah

Researcher profile · Semantic Scholar

K. Okkenhaug

Share profile

K. Okkenhaug — researcher profile on SciRah

h-index: 70
Works: 170
Citations: 22K

Most-cited papers

Ionic immune suppression within the tumour microenvironment limits T cell effector function
Robert L. Eil, S. Vodnala, D. Clever, C. Klebanoff +14 more
2016Nature625 citations Open access
Semantic Scholar
Phosphoinositide 3-kinase δ gene mutation predisposes to respiratory infection and airway damage
I. Angulo, O. Vadas, F. Garçon, E. Banham-Hall +40 more
2013Science620 citations Open access
Semantic Scholar
PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells
D. Finlay, E. Rosenzweig, Linda V. Sinclair, C. Feijoo-Carnero +5 more
2012Journal of Experimental Medicine577 citations Open access
Semantic Scholar
Inactivation of the PI3K p110δ breaks regulatory T cell-mediated immune tolerance to cancer
K. Ali, Dalya R. Soond, R. Piñeiro, T. Hagemann +10 more
2014Nature427 citations Open access
Semantic Scholar
Signalling by the phosphoinositide 3-kinase family in immune cells
K. Okkenhaug
2013Annual Review of Immunology425 citations Open access
Semantic Scholar
Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study
T. Coulter, Anita Chandra, C. Bacon, J. Babar +54 more
2017Journal of Allergy and Clinical Immunology414 citations Open access
Semantic Scholar
PI3K inhibitors are finally coming of age
B. Vanhaesebroeck, M. Perry, Jennifer R. Brown, F. André +1 more
2021Nature reviews. Drug discovery407 citations Open access
Semantic Scholar
Multi-tissue DNA methylation age predictor in mouse
Thomas M. Stubbs, M. Bonder, A. Stark, F. Krueger +22 more
2017Genome Biology371 citations Open access
Semantic Scholar
BACH2 regulates CD8+ T cell differentiation by controlling access of AP-1 factors to enhancers
R. Roychoudhuri, D. Clever, Peng Li, Y. Wakabayashi +22 more
2016Nature Immunology306 citations Open access
Semantic Scholar
PI3Kδ and primary immunodeficiencies
C. Lucas, Anita Chandra, S. Nejentsev, Alison M. Condliffe +1 more
2016Nature reviews. Immunology299 citations Open access
Semantic Scholar
PI3K inhibitors in inflammation, autoimmunity and cancer
A. Stark, S. Sriskantharajah, E. Hessel, K. Okkenhaug
2015Current opinion in pharmacology (Print)265 citations Open access
Semantic Scholar
Targeting PI3K in cancer: impact on tumor cells, their protective stroma, angiogenesis and immunotherapy
K. Okkenhaug, M. Graupera, B. Vanhaesebroeck
2016Cancer Discovery241 citations Open access
Semantic Scholar
Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis
Madhav Kishore, Kenneth C. P. Cheung, H. Fu, F. Bonacina +16 more
2017Immunity189 citations Open access
Semantic Scholar
Gene Targeting in Mice: a Review
H. Bouabe, K. Okkenhaug
2013Methods in molecular biology157 citations Open access
Semantic Scholar
Obesity-Induced Metabolic Stress Leads to Biased Effector Memory CD4+ T Cell Differentiation via PI3K p110δ-Akt-Mediated Signals
C. Mauro, Joanne Smith, D. Cucchi, D. Coe +12 more
2017Cell Metabolism152 citations Open access
Semantic Scholar
PI3Kβ Plays a Critical Role in Neutrophil Activation by Immune Complexes
S. Kulkarni, C. Sitaru, Z. Jakus, Karen E. Anderson +18 more
2011Science Signaling147 citations
Semantic Scholar
Compensation between CSF1R+ macrophages and Foxp3+ Treg cells drives resistance to tumor immunotherapy.
David Gyori, Ee Lyn Lim, F. Grant, Dominik Spensberger +5 more
2018JCI Insight124 citations Open access
Semantic Scholar
The PI3K p110δ Isoform Inhibitor Idelalisib Preferentially Inhibits Human Regulatory T Cell Function
S. Chellappa, K. Kushekhar, L. A. Munthe, G. Tjønnfjord +3 more
2019Journal of Immunology117 citations Open access
Semantic Scholar
Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis
Madhav Kishore, Kenneth C. P. Cheung, H. Fu, F. Bonacina +16 more
2018Immunity100 citations Open access
Semantic Scholar
Corrigendum: Inactivation of PI(3)K p110δ breaks regulatory T-cell-mediated immune tolerance to cancer
K. Ali, Dalya R. Soond, R. Piñeiro, T. Hagemann +10 more
2016Nature96 citations Open access
Semantic Scholar
Tumors induce de novo steroid biosynthesis in T cells to evade immunity
B. Mahata, Jhuma Pramanik, L. van der Weyden, K. Polański +13 more
2018Nature Communications95 citations Open access
Semantic Scholar
The Therapeutic Potential for PI3K Inhibitors in Autoimmune Rheumatic Diseases
E. Banham-Hall, M. Clatworthy, K. Okkenhaug
2012Open Rheumatology Journal93 citations Open access
Semantic Scholar
Cholesterol metabolism drives regulatory B cell IL-10 through provision of geranylgeranyl pyrophosphate
Jack A. Bibby, Harriet A. Purvis, T. Hayday, Anita Chandra +8 more
2020Nature Communications90 citations Open access
Semantic Scholar
Intermittent PI3Kδ inhibition sustains anti-tumour immunity and curbs irAEs
S. Eschweiler, C. Ramírez-Suástegui, Yingcong Li, E. King +38 more
2022Nature84 citations Open access
Semantic Scholar
The PI3K p110δ Regulates Expression of CD38 on Regulatory T Cells
D. Patton, M. Wilson, W. Rowan, Dalya R. Soond +1 more
2011PLoS ONE82 citations Open access
Semantic Scholar
Blockade of Phosphatidylinositol 3-Kinase (PI3K)δ or PI3Kγ Reduces IL-17 and Ameliorates Imiquimod-Induced Psoriasis-like Dermatitis
A. Roller, A. Perino, P. Dapavo, E. Soro +3 more
2012Journal of Immunology81 citations Open access
Semantic Scholar
CCR8 marks highly suppressive Treg cells within tumours but is dispensable for their accumulation and suppressive function
Sarah K. Whiteside, F. Grant, David Gyori, Alberto G. Conti +13 more
2021Immunology75 citations Open access
Semantic Scholar
PI3Kδ hyper-activation promotes development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner
A. Stark, Anita Chandra, Krishnendu Chakraborty, Rafeah Alam +12 more
2018Nature Communications70 citations Open access
Semantic Scholar
BACH2 drives quiescence and maintenance of resting Treg cells to promote homeostasis and cancer immunosuppression
F. Grant, Jie Yang, Rabab Nasrallah, J. Clarke +14 more
2020Journal of Experimental Medicine66 citations Open access
Semantic Scholar
PI3K Signaling in Normal B Cells and Chronic Lymphocytic Leukemia (CLL)
K. Okkenhaug, J. Burger
2015Current Topics in Microbiology and Immunology64 citations Open access
Semantic Scholar
The transcription factor BACH2 promotes tumor immunosuppression.
R. Roychoudhuri, Robert L. Eil, D. Clever, C. Klebanoff +18 more
2016Journal of Clinical Investigation60 citations Open access
Semantic Scholar
PI3K induces B-cell development and regulates B cell identity
Hend Abdelrasoul, Markus Werner, Corinna S. Setz, K. Okkenhaug +1 more
2018Scientific Reports55 citations Open access
Semantic Scholar
Phosphoinositide 3-kinase δ inhibition promotes antitumor responses but antagonizes checkpoint inhibitors.
Ee Lyn Lim, F. Cugliandolo, D. Rosner, David Gyori +2 more
2018JCI Insight50 citations Open access
Semantic Scholar
Idelalisib —targeting PI3Kδ in patients with B cell malignancies
J. Burger, K. Okkenhaug
2014Nature Reviews Clinical Oncology46 citations Open access
Semantic Scholar
IL-21 promotes CD4 T cell responses by PI3-kinase dependent upregulation of CD86 on B cells
K. Attridge, R. Kenefeck, Lukasz Wardzinski, O. Qureshi +4 more
2014Journal of Immunology45 citations Open access
Semantic Scholar
PI 3‐kinase delta enhances axonal PIP 3 to support axon regeneration in the adult CNS
Bart Nieuwenhuis, A. Barber, Rachel S. Evans, Craig S. Pearson +17 more
2019bioRxiv44 citations Open access
Semantic Scholar
Cowden’s syndrome with immunodeficiency
M. Browning, Anita Chandra, V. Carbonaro, K. Okkenhaug +1 more
2015Journal of Medical Genetics44 citations Open access
Semantic Scholar
Does the PI3K pathway promote or antagonize regulatory T cell development and function?
Dalya R. Soond, E. C. M. Slack, O. Garden, D. Patton +1 more
2012Front. Immun.43 citations Open access
Semantic Scholar
Autoimmunity or Lymphoma Helper Function but Does Not Lead to Pten Loss in CD4 T Cells Enhances Their
Dalya R. Soond, F. Garçon, D. Patton, J. Rolf +4 more
201240 citations
Semantic Scholar
PI3K in T Cell Adhesion and Trafficking
K. Johansen, Dominic P. Golec, Julie H. Thomsen, P. Schwartzberg +1 more
2021Frontiers in Immunology39 citations Open access
Semantic Scholar
Class IA PI3Ks regulate subcellular and functional dynamics of IDO1
Alberta Iacono, A. Pompa, F. De Marchis, E. Panfili +31 more
2020EMBO Reports39 citations Open access
Semantic Scholar
PI3Kδ regulates the magnitude of CD8+ T cell responses after challenge with Listeria monocytogenes
V. Q. Pearce, H. Bouabe, Amy R. MacQueen, V. Carbonaro +1 more
2015Journal of Immunology37 citations Open access
Semantic Scholar
Intravital Imaging of Adoptive T-Cell Morphology, Mobility and Trafficking Following Immune Checkpoint Inhibition in a Mouse Melanoma Model
Doreen Lau, F. Garçon, Anita Chandra, Laura M. Lechermann +5 more
2020Frontiers in Immunology36 citations Open access
Semantic Scholar
Phosphoinositide 3‐kinase δ is a regulatory T‐cell target in cancer immunotherapy
Ee Lyn Lim, K. Okkenhaug
2019Immunology35 citations Open access
Semantic Scholar
C5a impairs phagosomal maturation in the neutrophil through phosphoproteomic remodeling
Alexander J. T. Wood, A. Vassallo, M. Ruchaud-Sparagano, J. Scott +10 more
2020JCI Insight33 citations Open access
Semantic Scholar
Immunodeficiency, autoimmune thrombocytopenia and enterocolitis caused by autosomal recessive deficiency of PIK3CD-encoded phosphoinositide 3-kinase δ
D. Swan, D. Aschenbrenner, C. Lamb, Krishnendu Chakraborty +16 more
2019Haematologica32 citations Open access
Semantic Scholar
A CRISPR screen targeting PI3K effectors identifies RASA3 as a negative regulator of LFA-1–mediated adhesion in T cells
K. Johansen, Dominic P. Golec, Bonnie Huang, Chung Park +14 more
2022Science Signaling30 citations Open access
Semantic Scholar
Rules of engagement: distinct functions for the four class I PI3K catalytic isoforms in immunity
K. Okkenhaug
2013Annals of the New York Academy of Sciences28 citations Open access
Semantic Scholar
BACH2 restricts NK cell maturation and function, limiting immunity to cancer metastasis
C. Imianowski, Sarah K. Whiteside, T. Lozano, Alexander C. Evans +16 more
2022Journal of Experimental Medicine27 citations Open access
Semantic Scholar
PI3K Signaling in B Cell and T Cell Biology
K. Okkenhaug, M. Turner, M. Gold
2014Frontiers in Immunology27 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

R. Roychoudhuri×8
Invite
R. Roychoudhuri — researcher profile on SciRah
Anita Chandra×8
Invite
Anita Chandra — researcher profile on SciRah
B. Vanhaesebroeck×7
Invite
B. Vanhaesebroeck — researcher profile on SciRah
Robert L. Eil×5
Invite
Robert L. Eil — researcher profile on SciRah

×5

Invite

Dalya R. Soond — researcher profile on SciRah

Invite

Ee Lyn Lim — researcher profile on SciRah

Invite

F. Grant — researcher profile on SciRah

V. Carbonaro×4

Invite

V. Carbonaro — researcher profile on SciRah

Invite

F. Garçon — researcher profile on SciRah

Invite

P. Hawkins — researcher profile on SciRah

Alison M. Condliffe×4

Invite

Alison M. Condliffe — researcher profile on SciRah

S. Nejentsev×4

Invite

S. Nejentsev — researcher profile on SciRah