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D. Aschenbrenner · SciRah

Researcher profile · Semantic Scholar

D. Aschenbrenner

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D. Aschenbrenner — researcher profile on SciRah

h-index: 17
Works: 41
Citations: 1,932

Most-cited papers

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
†. Consortium, D. Ahern, Zhi-Chao Ai, M. Ainsworth +203 more
2021medRxiv310 citations Open access
Semantic Scholar
The gut mycobiome in health, disease, and clinical applications in association with the gut bacterial microbiome assembly.
Fen Zhang, D. Aschenbrenner, Ji Youn Yoo, Tao Zuo
2022The Lancet Microbe304 citations Open access
Semantic Scholar
A biallelic mutation in IL6ST encoding the GP130 co-receptor causes immunodeficiency and craniosynostosis
T. Schwerd, S. Twigg, D. Aschenbrenner, Santiago Manrique +21 more
2017Journal of Experimental Medicine174 citations Open access
Semantic Scholar
Transcriptional signature of human pro-inflammatory TH17 cells identifies reduced IL10 gene expression in multiple sclerosis
Dan Hu, Samuele Notarbartolo, T. Croonenborghs, B. Patel +16 more
2017Nature Communications126 citations Open access
Semantic Scholar
Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome
V. Béziat, S. Tavernier, Yin-Huai Chen, Cindy S. Ma +55 more
2020Journal of Experimental Medicine119 citations Open access
Semantic Scholar
Deconvolution of monocyte responses in inflammatory bowel disease reveals an IL-1 cytokine network that regulates IL-23 in genetic and acquired IL-10 resistance
D. Aschenbrenner, M. Quaranta, S. Banerjee, N. Ilott +15 more
2020Gut104 citations Open access
Semantic Scholar
Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice
Lin Wang, D. Aschenbrenner, Zhiyang Zeng, Xi-Ya Cao +51 more
2021Nature Genetics99 citations Open access
Semantic Scholar
A longitudinal single-cell atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease
Tom Thomas, M. Friedrich, C. Rich-Griffin, M. Pohin +45 more
2024Nature Immunology95 citations Open access
Semantic Scholar
Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis
D. Trzupek, Melanie L. Dunstan, Antony J. Cutler, Mercede Lee +9 more
2019bioRxiv94 citations Open access
Semantic Scholar
Immunoregulatory and tissue-residency programs modulated by c-MAF in human TH17 cells
D. Aschenbrenner, Mathilde Foglierini, D. Jarrossay, Dan Hu +5 more
2018Nature Immunology90 citations Open access
Semantic Scholar
An integrated taxonomy for monogenic inflammatory bowel disease
C. Bolton, C. Smillie, S. Pandey, R. Elmentaite +32 more
2021Gastroenterology88 citations Open access
Semantic Scholar
Selective loss of function variants in IL6ST cause Hyper-IgE syndrome with distinct impairments of T-cell phenotype and function
T. Shahin, D. Aschenbrenner, D. Çağdaş, S. Bal +13 more
2018Haematologica83 citations Open access
Semantic Scholar
Absence of GP130 cytokine receptor signaling causes extended Stüve-Wiedemann syndrome
Yin-Huai Chen, G. Grigelioniene, P. T. Newton, J. Gullander +23 more
2020Journal of Experimental Medicine55 citations Open access
Semantic Scholar
ERK phosphorylation and miR-181a expression modulate activation of human memory TH17 cells
F. Mele, C. Basso, Cristina Leoni, D. Aschenbrenner +5 more
2015Nature Communications41 citations Open access
Semantic Scholar
Immunodeficiency, autoimmune thrombocytopenia and enterocolitis caused by autosomal recessive deficiency of PIK3CD-encoded phosphoinositide 3-kinase δ
D. Swan, D. Aschenbrenner, C. Lamb, Krishnendu Chakraborty +16 more
2019Haematologica32 citations Open access
Semantic Scholar
A variant in IL6ST with a selective IL-11 signaling defect in human and mouse
T. Schwerd, Freia Krause, S. Twigg, D. Aschenbrenner +16 more
2020Bone Research22 citations Open access
Semantic Scholar
Immune–epithelial–stromal networks define the cellular ecosystem of the small intestine in celiac disease
M. FitzPatrick, A. Antanaviciute, Melanie L. Dunstan, Karolina Künnapuu +22 more
2025Nature Immunology19 citations Open access
Semantic Scholar
Pathogenic Interleukin-10 Receptor Alpha Variants in Humans — Balancing Natural Selection and Clinical Implications
D. Aschenbrenner, Zi-Qing Ye, Ying Zhou, Wenhui Hu +11 more
2022Journal of Clinical Immunology18 citations Open access
Semantic Scholar
Hermansky-Pudlak syndrome type 1 causes impaired anti-microbial immunity and inflammation due to dysregulated immunometabolism
Athena Cavounidis, S. Pandey, M. Capitani, M. Friedrich +18 more
2022Mucosal Immunology11 citations Open access
Semantic Scholar
A method for the inference of cytokine interaction networks
Joanneke E Jansen, D. Aschenbrenner, H. Uhlig, M. Coles +1 more
2022PLoS Comput. Biol.10 citations Open access
Semantic Scholar
A longitudinal single-cell therapeutic atlas of anti-tumour necrosis factor treatment in inflammatory bowel disease
T. Thomas, C. Rich-Griffin, M. Pohin, M. Friedrich +30 more
2023bioRxiv9 citations Open access
Semantic Scholar
Negative regulation of ACE2 by interferons in vivo and its genetic control
M. Ansari, E. Marchi, N. Ramamurthy, D. Aschenbrenner +19 more
20209 citations Open access
Semantic Scholar
A gene locus that controls expression of ACE2 in virus infection
M. Ansari, E. Marchi, N. Ramamurthy, D. Aschenbrenner +20 more
2020medRxiv7 citations Open access
Semantic Scholar
A variant in IL6ST with a selective IL-11 signaling defect in human and mouse.
T. Schwerd, Freia Krause, S. Twigg, D. Aschenbrenner +16 more
2020Bone Research6 citations Open access
Semantic Scholar
An isoform quantitative trait locus in SBNO2 links genetic susceptibility to Crohn’s disease with defective antimicrobial activity
D. Aschenbrenner, I. Nassiri, S. Venkateswaran, S. Pandey +6 more
2024Nature Communications4 citations Open access
Semantic Scholar
Publisher Correction: An immunoregulatory and tissue-residency program modulated by c-MAF in human TH17 cells
D. Aschenbrenner, Mathilde Foglierini, D. Jarrossay, Dan Hu +5 more
2018Nature Immunology4 citations Open access
Semantic Scholar
Blood characteristics of patients with type 2 diabetes and response of their peripheral blood mononuclear cells to inhibitors of the NLRP3-inflammasome and caspase-1.
J. de Paula Souza, Justus S. Fischer, Karine Jeanneau, C. Allard +15 more
2025Canadian Journal of Diabetes3 citations Open access
Semantic Scholar
Author Correction: Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice
Lin Wang, D. Aschenbrenner, Zhiyang Zeng, Xi-Ya Cao +52 more
2022Nature Genetics2 citations Open access
Semantic Scholar
In vivo negative regulation of SARS-CoV-2 receptor, ACE2, by interferons and its genetic control
M. Ansari, E. Marchi, N. Ramamurthy, D. Aschenbrenner +21 more
2021Wellcome Open Research2 citations Open access
Semantic Scholar
Simultaneous mRNA and protein quantification at the single-cell level delineates trajectories of CD4+ T-cell differentiation
D. Trzupek, Melanie L. Dunstan, Antony J. Cutler, Mercede Lee +6 more
20192 citations Open access
Semantic Scholar
BCG Vaccine–Associated Complications in Patients with PTEN Hamartoma Tumor Syndrome
H. Taylor, D. Aschenbrenner, M. Thomson, Hannah H. Chen +1 more
2021Journal of Clinical Immunology1 citations
Semantic Scholar
Discovery of CD80 and CD86 as recent activation markers on regulatory T cells by protein-RNA single-cell analysis
D. Trzupek, Melanie L. Dunstan, Antony J. Cutler, Mercede Lee +9 more
2020Genome Medicine1 citations Open access
Semantic Scholar
Correction: Dominant-negative mutations in human IL6ST underlie hyper-IgE syndrome
V. Béziat, S. Tavernier, Yin-Huai Chen, Cindy S. Ma +56 more
2020Journal of Experimental Medicine1 citations Open access
Semantic Scholar
Systems-level analysis of monocyte responses in inflammatory bowel disease identifies IL-10 and IL-1 cytokine networks that regulate IL-23
D. Aschenbrenner, M. Quaranta, S. Banerjee, N. Ilott +15 more
2019bioRxiv1 citations Open access
Semantic Scholar
Translating from mouse to man to better understand immune-mediated inflammatory diseases
D. Aschenbrenner, R. Siegel
2023Cell Reports Medicine0 citations Open access
Semantic Scholar
A method for the inference of cytokine interaction networks – Supporting information
J. Jansen, D. Aschenbrenner, H. Uhlig, M. Coles +1 more
20220 citations
Semantic Scholar
Author Correction: Gain-of-function variants in SYK cause immune dysregulation and systemic inflammation in humans and mice
Lin Wang, D. Aschenbrenner, Zhiyang Zeng, Xi-Ya Cao +53 more
2022Nature Genetics0 citations Open access
Semantic Scholar
Su1800 CHARACTERIZING THE ROLE OF GAIN-OF-FUNCTION SYK MUTATIONS IN THE PATHOGENESIS OF INFLAMMATORY DISEASES.
M. Mehta, Lin Wang, D. Aschenbrenner, N. Warner +11 more
20200 citations
Semantic Scholar
P037 Bacterial handling defect in macrophages of patients with defects in glucose-6-phosphate metabolism and Crohn’s disease like intestinal inflammation
S. Pandey, K. Balagopal, D. Aschenbrenner, M. Capitani +7 more
20180 citations
Semantic Scholar
Transcriptional regulation and epigenetic control of human TH17 effector function
D. Aschenbrenner
20150 citations
Semantic Scholar
Evaluating IC31-induced cellular and mucosal humoral immune protective mechanisms against intracellular bacterial infections using a well established Chlamydia pneumoniae model
D. Aschenbrenner
20100 citations
Semantic Scholar

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