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Robert L. Eil · SciRah

Researcher profile · Semantic Scholar

Robert L. Eil

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Robert L. Eil — researcher profile on SciRah

h-index: 20
Works: 66
Citations: 4,731

Most-cited papers

Identification of essential genes for cancer immunotherapy
Shashank J. Patel, N. Sanjana, R. Kishton, A. Eidizadeh +20 more
2017Nature786 citations Open access
Semantic Scholar
Ionic immune suppression within the tumour microenvironment limits T cell effector function
Robert L. Eil, S. Vodnala, D. Clever, C. Klebanoff +14 more
2016Nature624 citations Open access
Semantic Scholar
T cell stemness and dysfunction in tumors are triggered by a common mechanism
S. Vodnala, Robert L. Eil, R. Kishton, Madhusudhanan Sukumar +15 more
2019Science505 citations Open access
Semantic Scholar
Mitochondrial membrane potential identifies cells with enhanced stemness for cellular therapy
Madhusudhanan Sukumar, Jie Liu, Gautam U. Mehta, Shashank J. Patel +21 more
2015Cell Metabolism374 citations Open access
Semantic Scholar
Akt inhibition enhances expansion of potent tumor-specific lymphocytes with memory cell characteristics
Joseph G. Crompton, Madhusudhanan Sukumar, R. Roychoudhuri, D. Clever +20 more
2014Cancer Research325 citations Open access
Semantic Scholar
BACH2 regulates CD8+ T cell differentiation by controlling access of AP-1 factors to enhancers
R. Roychoudhuri, D. Clever, Peng Li, Y. Wakabayashi +22 more
2016Nature Immunology306 citations Open access
Semantic Scholar
T cell oxygen-sensing proteins establish an immunologically tolerant metastatic niche
D. Clever, R. Roychoudhuri, Michael G. Constantinides, Michael H. Askenase +13 more
2016Cell225 citations Open access
Semantic Scholar
Memory T cell-driven differentiation of naive cells impairs adoptive immunotherapy.
C. Klebanoff, C. D. Scott, A. Leonardi, Tori N. Yamamoto +23 more
2015Journal of Clinical Investigation223 citations Open access
Semantic Scholar
Inhibition of AKT signaling uncouples T cell differentiation from expansion for receptor-engineered adoptive immunotherapy.
C. Klebanoff, Joseph G. Crompton, A. Leonardi, Tori N. Yamamoto +15 more
2017JCI Insight198 citations Open access
Semantic Scholar
Cish actively silences TCR signaling in CD8+ T cells to maintain tumor tolerance
D. Palmer, G. Guittard, Zulmarie Franco, Joseph G. Crompton +16 more
2015Journal of Experimental Medicine197 citations Open access
Semantic Scholar
Multi-phenotype CRISPR-Cas9 Screen Identifies p38 Kinase as a Target for Adoptive Immunotherapies
Devikala Gurusamy, Amanda N. Henning, Tori N. Yamamoto, Zhi-Ya Yu +14 more
2020Cancer Cell146 citations Open access
Semantic Scholar
The interplay of effector and regulatory T cells in cancer.
R. Roychoudhuri, Robert L. Eil, N. Restifo
2015Current Opinion in Immunology145 citations
Semantic Scholar
T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy
Tori N. Yamamoto, Ping-Hsien Lee, S. Vodnala, Devikala Gurusamy +14 more
2019Journal of Clinical Investigation137 citations Open access
Semantic Scholar
CCR8 marks highly suppressive Treg cells within tumours but is dispensable for their accumulation and suppressive function
Sarah K. Whiteside, F. Grant, David Gyori, Alberto G. Conti +13 more
2021Immunology75 citations Open access
Semantic Scholar
BACH2 drives quiescence and maintenance of resting Treg cells to promote homeostasis and cancer immunosuppression
F. Grant, Jie Yang, Rabab Nasrallah, J. Clarke +14 more
2020Journal of Experimental Medicine66 citations Open access
Semantic Scholar
Fas/CD95 prevents autoimmunity independently of lipid raft localization and efficient apoptosis induction
Anthony C. Cruz, M. Ramaswamy, Claudia Ouyang, C. Klebanoff +12 more
2016Nature Communications62 citations Open access
Semantic Scholar
The transcription factor BACH2 promotes tumor immunosuppression.
R. Roychoudhuri, Robert L. Eil, D. Clever, C. Klebanoff +18 more
2016Journal of Clinical Investigation60 citations Open access
Semantic Scholar
Novel ‘elements’ of immune suppression within the tumor microenvironment
Devikala Gurusamy, D. Clever, Robert L. Eil, N. Restifo
2017Cancer immunology research57 citations Open access
Semantic Scholar
Updated Management of Colorectal Cancer Liver Metastases: Scientific Advances Driving Modern Therapeutic Innovations
Ranish K. Patel, Shahrose Rahman, Issac R. Schwantes, Alexandra Bartlett +11 more
2023Cellular and Molecular Gastroenterology and Hepatology52 citations Open access
Semantic Scholar
Nomogram for predicting the benefit of neoadjuvant chemoradiotherapy for patients with esophageal cancer: A SEER‐Medicare analysis
Robert L. Eil, B. Diggs, Samuel J. Wang, J. P. Dolan +2 more
2014Cancer44 citations
Semantic Scholar
Hepatectomy is associated with improved oncologic outcomes in recurrent colorectal liver metastases: A propensity-matched analysis.
T. Sutton, Liam H. Wong, B. Walker, E. N. Dewey +7 more
2022Surgery19 citations
Semantic Scholar
Surgical and oncologic outcomes following repeat hepatic resection of colorectal liver metastasis: Who benefits?
Liam H. Wong, T. Sutton, B. Walker, C. Lopez +5 more
2021American Journal of Surgery17 citations
Semantic Scholar
Bile duct involvement portends poor prognosis in resected gallbladder carcinoma.
Robert L. Eil, P. Hansen, Maria A. Cassera, S. Orloff +3 more
2013Gastrointestinal cancer research : GCR16 citations
Semantic Scholar
Hepatic signal transducer and activator of transcription‐3 signalling drives early‐stage pancreatic cancer cachexia via suppressed ketogenesis
Paige C. Arneson-Wissink, Heike Mendez, Katherine R. Pelz, J. Dickie +5 more
2024Journal of Cachexia, Sarcopenia and Muscle15 citations Open access
Semantic Scholar
Whole-Exome Sequencing Reveals Frequent Genetic Alterations in BAP 1 , NF 2 , CDKN 2 A , and CUL 1 in Malignant Pleural Mesothelioma
E. Laconi, R. Hegele, Michael W. Lieberman, R. Srinivasan +79 more
201415 citations
Semantic Scholar
Intracellular K+ limits T cell exhaustion and preserves antitumor function
Camille Collier, Kelly Wucherer, Matthew McWhorter, Chelsea Jenkins +3 more
2023bioRxiv10 citations Open access
Semantic Scholar
A Modified Floxuridine Reduced-Dose Protocol for Patients with Unresectable Colorectal Liver Metastases Treated with Hepatic Arterial Infusion
Issac R. Schwantes, Ranish K. Patel, Adel Kardosh, J. Paxton +7 more
2024Annals of Surgical Oncology7 citations
Semantic Scholar
Significance of Pre-operative Radiographic Pancreatic Density in Predicting Pancreatic Fistula after Surgery for Pancreatic Neuroendocrine Tumors
Y. Assadipour, S. Azoury, Nicholas N Schaub, Y. Hong +6 more
2014American Journal of Surgery7 citations Open access
Semantic Scholar
Intracellular K+ limits T-cell exhaustion and preserves antitumor function
Camille Collier, Kelly Wucherer, Matthew McWhorter, Chelsea Jenkins +3 more
2023Cancer immunology research4 citations Open access
Semantic Scholar
Surgical timing after preoperative chemotherapy is associated with oncologic outcomes in resectable colorectal liver metastases
T. Sutton, Liam H. Wong, B. Walker, E. Dewey +6 more
2022Journal of Surgical Oncology4 citations
Semantic Scholar
A phase II trial of induction systemic mFOLFIRINOX followed by hepatic arterial infusion of floxuridine and dexamethasone given concurrently with systemic mFOLFIRI as a first-line therapy in patients with unresectable liver-dominant intrahepatic cholangiocarcinoma (HELIX-1).
S. Mayo, Ranish K. Patel, Brett S Walker, Robert L. Eil +16 more
2024Journal of Clinical Oncology3 citations
Semantic Scholar
Conventional hepatic arterial anatomy? Novel findings and insights of a multi-disciplinary hepatic arterial infusion pump program.
B. Walker, T. Sutton, Robert L. Eil, E. Korngold +3 more
2021American Journal of Surgery3 citations
Semantic Scholar
Elevated potassium levels suppress T cell activation within tumors
Robert L. Eil, R. Roychoudhuri, D. Clever, Shashank J. Patel +5 more
2015Journal of Immunotherapy for Cancer3 citations Open access
Semantic Scholar
Intracranial Hemangiopericytoma Focally Recurrent to the Pelvis
Robert L. Eil, K. Lu, George R. Wettach, V. Tsikitis
20123 citations Open access
Semantic Scholar
255 A novel approach to limit the off-tumor toxicity of tumor-associated antigen specific CAR-T cells
Alexandra Bartlett, Matthew McWhorter, Jessica Briones, Chelsea Jenkins +1 more
2024Regular and Young Investigator Award Abstracts2 citations Open access
Semantic Scholar
Traumatic ventricular septal defect resulting in severe pulmonary hypertension
J. Crompton, Benjamin A. Nacev, Trevor C. Upham, S. Azoury +3 more
2014Journal of Surgical Case Reports2 citations Open access
Semantic Scholar
Tumor-derived antioxidants suppress immunity by depriving T cells of reactive oxygen species.
Alexander J. Wesolowski, Ardon M. Pillay, Panagiota Vardaka, Rabab Nasrallah +28 more
2026Science1 citations
Semantic Scholar
Interleukin 6 Drives Durable T Cell-Mediated Immunity to Pancreatic Cancer
Paige C. Arneson-Wissink, Alexandra Bartlett, Heike Mendez, Xin-Xia Zhu +12 more
2024bioRxiv1 citations Open access
Semantic Scholar
Concurrent preoperative eribulin and radiation for resectable retroperitoneal liposarcoma: a phase 1B study
Lara E. Davis, Limin Zhu, S. Mayo, Emile Latour +13 more
2024Research Square1 citations Open access
Semantic Scholar
Abstract 1463: Ionic immune suppression within the tumor microenvironment limits T cell effector function
Robert L. Eil, R. Roychoudhuri, Madhu Sukumar, D. Clever +4 more
20161 citations
Semantic Scholar
New methodology, tools, and protocolized analysis are needed to advance individualized treatment paradigms in esophageal cancer.
Robert L. Eil, C. R. Thomas
2014Diseases of the esophagus1 citations
Semantic Scholar
CAR T-Cell Therapy for Solid Tumors: Clinical Challenges and Current Advancements.
A. Gutierrez, Robert L. Eil
2026Surgical Oncology Clinics of North America0 citations
Semantic Scholar
The post-transcriptional regulator HuR promotes immune evasion in pancreatic ductal adenocarcinoma.
Yi-Fei Guo, Jennifer M. Finan, Alexandra Q. Bartlett, Katherine R. Pelz +20 more
2026Cancer immunology research0 citations
Semantic Scholar
34A Single-Center Preliminary Experience with Systemic Chemo-Immunotherapy in Combination with Hepatic Arterial Infusion Floxuridine in Patients with Liver-Confined Intrahepatic Cholangiocarcinoma
Adel Kardosh, Ranish K. Patel, S. Smith, Kathryn L Fowler +9 more
2026The Oncologist0 citations Open access
Semantic Scholar
Increased Glucose Availability Sensitizes Pancreatic Cancer to Macrophage-Targeting Immunotherapies
Jonathan J. Hue, Mehrdad Zarei, Priyashree Sunita, Sami O. Abul-Khoudoud +15 more
2026Cancer Research Communications0 citations Open access
Semantic Scholar
Concurrent preoperative eribulin and radiation for resectable retroperitoneal liposarcoma: a phase 1B study.
Lara E. Davis, Limin Zhu, S. Mayo, Emile Latour +13 more
2026Cancer Treatment and Research Communications0 citations Open access
Semantic Scholar
1250 Post-transcriptional regulator HuR promotes immune evasion in pancreatic ductal adenocarcinoma
Yi-Fei Guo, Jennifer M. Finan, Alexandra Bartlett, S. Sivagnanam +14 more
2025Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
388 Antigen-dependent CAR T cell toxicity is amplified by neutrophil-mediated crosstalk in epithelial cancers
Alexandra Bartlett, Yi-Fei Guo, Matthew McWhorter, Olivia Huber +7 more
2025Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
Abstract 4819: Pulmonary neutrophil-CAR T cell crosstalk amplifies antigen-specific off tumor toxicity
Robert L. Eil, Alexandra Q. Bartlett, Matthew McWhorter, Chelsea Jenkins +1 more
2025Cancer Research0 citations
Semantic Scholar
Abstract 906: High K+ in tumors impairs T cell effector activity via lysosomal acidification-induced autophagy
Robert L. Eil, Chelsea Jenkins, Jessica Briones, Matthew McWhorter +1 more
2025Cancer Research0 citations
Semantic Scholar

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N. Restifo×19
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N. Restifo — researcher profile on SciRah
R. Roychoudhuri×17
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R. Roychoudhuri — researcher profile on SciRah
C. Klebanoff×14
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C. Klebanoff — researcher profile on SciRah
Madhusudhanan Sukumar×13
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Madhusudhanan Sukumar — researcher profile on SciRah

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D. Clever — researcher profile on SciRah

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D. Palmer — researcher profile on SciRah

Shashank J. Patel×11

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Shashank J. Patel — researcher profile on SciRah

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Zhi-Ya Yu — researcher profile on SciRah

L. Gattinoni×10

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L. Gattinoni — researcher profile on SciRah

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S. Mayo — researcher profile on SciRah

Tori N. Yamamoto×8

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Tori N. Yamamoto — researcher profile on SciRah

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J. Pan — researcher profile on SciRah