Researcher profile · Semantic Scholar

S. Kulkarni

h-index: 25
Works: 36
Citations: 3,744

Most-cited papers

PI 3-kinase p110β: a new target for antithrombotic therapy
S. Jackson, S. Schoenwaelder, Isaac Goncalves, W. Nesbitt +22 more
2005Nature Medicine545 citations
Semantic Scholar
Signaling events underlying thrombus formation
S. Jackson, W. Nesbitt, S. Kulkarni
2003Journal of Thrombosis and Haemostasis413 citations Open access
Semantic Scholar
A revised model of platelet aggregation.
S. Kulkarni, Sacha M. Dopheide, Cindy L. Yap, C. Ravanat +7 more
2000Journal of Clinical Investigation374 citations Open access
Semantic Scholar
SCFAs Induce Mouse Neutrophil Chemotaxis through the GPR43 Receptor
M. Vinolo, G. Ferguson, S. Kulkarni, George Damoulakis +5 more
2011PLoS ONE285 citations Open access
Semantic Scholar
PI 3-kinase p110beta: a new target for antithrombotic therapy.
S. Jackson, S. Schoenwaelder, Isaac Goncalves, W. Nesbitt +22 more
2005Nature Medicine285 citations
Semantic Scholar
Intercellular calcium communication regulates platelet aggregation and thrombus growth
W. Nesbitt, Simon Giuliano, S. Kulkarni, Sacha M. Dopheide +2 more
2003Journal of Cell Biology191 citations Open access
Semantic Scholar
Distinct Glycoprotein Ib/V/IX and Integrin αIIbβ3-dependent Calcium Signals Cooperatively Regulate Platelet Adhesion under Flow*
W. Nesbitt, S. Kulkarni, Simon Giuliano, Isaac Goncalves +5 more
2002Journal of Biological Chemistry169 citations Open access
Semantic Scholar
PI(3)Kγ has an important context-dependent role in neutrophil chemokinesis
G. Ferguson, Laura Milne, S. Kulkarni, T. Sasaki +12 more
2007Nature Cell Biology158 citations
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PI3Kβ Plays a Critical Role in Neutrophil Activation by Immune Complexes
S. Kulkarni, C. Sitaru, Z. Jakus, Karen E. Anderson +18 more
2011Science Signaling147 citations
Semantic Scholar
PI(3)Kgamma has an important context-dependent role in neutrophil chemokinesis.
G. Ferguson, Laura Milne, S. Kulkarni, T. Sasaki +12 more
2007Nature Cell Biology141 citations
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The von Willebrand Factor-Glycoprotein Ib/V/IX Interaction Induces Actin Polymerization and Cytoskeletal Reorganization in Rolling Platelets and Glycoprotein Ib/V/IX-transfected Cells*
Yu-Ping Yuan, S. Kulkarni, P. Ulsemer, S. Cranmer +11 more
1999Journal of Biological Chemistry128 citations Open access
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Synergistic adhesive interactions and signaling mechanisms operating between platelet glycoprotein Ib/IX and integrin alpha IIbbeta 3. Studies in human platelets ans transfected Chinese hamster ovary cells.
Cindy L. Yap, S. Hughan, S. Cranmer, W. Nesbitt +7 more
2000Journal of Biological Chemistry104 citations Open access
Semantic Scholar
CD18-dependent activation of the neutrophil NADPH oxidase during phagocytosis of Escherichia coli or Staphylococcus aureus is regulated by class III but not class I or II PI3Ks.
Karen E. Anderson, Keith B. Boyle, Keith Davidson, Tamara A. M. Chessa +7 more
2008Blood100 citations Open access
Semantic Scholar
Platelet Factor XIII and Calpain Negatively Regulate Integrin αIIbβ3 Adhesive Function and Thrombus Growth*
S. Kulkarni, S. Jackson
2004Journal of Biological Chemistry98 citations Open access
Semantic Scholar
Distinct glycoprotein Ib/V/IX and integrin alpha IIbbeta 3-dependent calcium signals cooperatively regulate platelet adhesion under flow.
W. Nesbitt, S. Kulkarni, Simon Giuliano, Isaac Goncalves +5 more
2002Journal of Biological Chemistry80 citations
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Conversion of platelets from a proaggregatory to a proinflammatory adhesive phenotype: role of PAF in spatially regulating neutrophil adhesion and spreading.
S. Kulkarni, K. Woollard, Stephen Thomas, David Oxley +1 more
2007Blood72 citations
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Distinct Substrate Specificities and Functional Roles for the 78- and 76-kDa Forms of μ-Calpain in Human Platelets*
S. Schoenwaelder, S. Kulkarni, H. Salem, S. Imajoh‐ohmi +3 more
1997Journal of Biological Chemistry67 citations Open access
Semantic Scholar
Coincident signals from GPCRs and receptor tyrosine kinases are uniquely transduced by PI3Kβ in myeloid cells
D. Houslay, Karen E. Anderson, Tamara A. M. Chessa, S. Kulkarni +5 more
2016Science Signaling63 citations Open access
Semantic Scholar
Raised Plasma Soluble P-Selectin in Peripheral Arterial Occlusive Disease Enhances Leukocyte Adhesion
Kevin J. Woollard, D. Kling, S. Kulkarni, Anthony M. Dart +2 more
2005Circulation Research63 citations Open access
Semantic Scholar
Platelet factor XIII and calpain negatively regulate integrin alphaIIbbeta3 adhesive function and thrombus growth.
S. Kulkarni, S. Jackson
2004Journal of Biological Chemistry53 citations
Semantic Scholar
Functional Redundancy of Class I Phosphoinositide 3-Kinase (PI3K) Isoforms in Signaling Growth Factor-Mediated Human Neutrophil Survival
J. Juss, R. Hayhoe, C. Owen, I. Bruce +8 more
2012PLoS ONE52 citations Open access
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Quantitation of class IA PI3Ks in mice reveals p110-free-p85s and isoform-selective subunit associations and recruitment to receptors
N. Tsolakos, T. Durrant, Tamara A. M. Chessa, S. Suire +7 more
2018Proceedings of the National Academy of Sciences of the United States of America48 citations Open access
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Techniques to examine platelet adhesive interactions under flow.
S. Kulkarni, W. Nesbitt, Sacha M. Dopheide, S. Hughan +2 more
2004Methods in molecular biology40 citations
Semantic Scholar
The Phosphoinositide 3-Kinase Isoform PI3Kβ Regulates Osteoclast-Mediated Bone Resorption in Humans and Mice
David Gyori, D. Csete, Szilvia Benkő, S. Kulkarni +6 more
2014Arthritis & Rheumatology28 citations Open access
Semantic Scholar
Synergistic Adhesive Interactions and Signaling Mechanisms Operating between Platelet Glycoprotein Ib/IX and Integrin αIIbβ3
Cindy L. Yap, S. Hughan, S. Cranmer, W. Nesbitt +7 more
2000Journal of Biological Chemistry26 citations Open access
Semantic Scholar
CD 18-dependent activation of the neutrophil NADPH oxidase during phagocytosis of Escherichia coli or Staphylococcus aureus is regulated by class III but not class I or II PI 3 Ks
Karen E. Anderson, Keith B. Boyle, Keith Davidson, Tamara A. M. Chessa +7 more
200812 citations
Semantic Scholar
CELL BIOLOGY AND METABOLISM
S. Jackson, H. Salem, F. Lanza, D. Williamson +7 more
20133 citations
Semantic Scholar
CD18-dependent activation of the neutrophil NADPH oxidase during phagocytosis of E.coli or S.aureus is regulated by Class III but not Class I or II PI3Ks
Karen E. Anderson, Keith B. Boyle, Keith Davidson, Tamara A. M. Chessa +8 more
20082 citations
Semantic Scholar
Raised soluble P-selectin in peripheral arterial occlusive disease enhances leukocyte-platelet adhesion independent of circulating microparticle levels
K. Woollard, D. Kling, S. Kulkarni, A. Dart +2 more
20061 citations
Semantic Scholar
or II PI3Ks phagocytosis of E.coli or S.aureus is regulated by Class III but not Class I CD18-dependent activation of the neutrophil NADPH oxidase during
A. Sindrilaru, K. Scharffetter-Kochanek, Oliver Rausch, L. Stephens +2 more
20130 citations
Semantic Scholar
Complexes PI 3 K { beta } Plays a Critical Role in Neutrophil Activation by Immune `
B. Vanhaesebroeck, L. Stephens, P. Hawkins, G. Jarvis +19 more
20110 citations
Semantic Scholar
CD18-dependent activation of the neutrophil NADPH oxidase during phagocytosis of Escherichia coli or Staphylococcus aureus is regulated by class III but not class I or II PI3Ks. Commentary
Adam D. Kennedy, F. DeLeo, Karen E. Anderson, Keith B. Boyle +9 more
20080 citations
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Conversion of Platelets from a Pro-Aggregatory to a Pro- Inflammatory Adhesive Phenotype: ROLE OF PAF IN SPATIALLY
S. Kulkarni, K. Woollard, S. A. Thomas, David Oxley
20070 citations
Semantic Scholar
SOLUBLE P-SELECTIN INCREASES NEUTROPHIL ADHESION TO SPREAD PLATELET MONOLAYERS IN SHEAR FLOW: P1.161
K. Woollard, S. Kulkarni, S. Jackson, A. Dart +2 more
20040 citations
Semantic Scholar
ALPHA M AND ALPHA X BETA2 INTEGRINS CO-OPERATE TO MEDIATE MONOCYTE ADHESION TO PLATELETS UNDER FLOW
V. Kanagasundaram, T. Georgakopoulos, S. Kulkarni, W. Nesbitt +2 more
20040 citations
Semantic Scholar
Synergistic adhesive interactions and signaling mechanisms operating between platelet gp ib/ix and integrin αiibβ3: studies in human platelets and transfected K562 and CHO cells
S. Jackson, T. Domagala, S. Hughan, S. Cranmer +6 more
20000 citations
Semantic Scholar

Sacha M. Dopheide

×12

Cindy L. Yap×10

Karen E. Anderson×10

H. Salem×10

Yu-Ping Yuan×7

Simon Giuliano×7

S. Hughan×7

I. Harper×7