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S. Vodnala · SciRah

Researcher profile · Semantic Scholar

S. Vodnala

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S. Vodnala — researcher profile on SciRah

h-index: 20
Works: 48
Citations: 3,616

Most-cited papers

Identification of essential genes for cancer immunotherapy
Shashank J. Patel, N. Sanjana, R. Kishton, A. Eidizadeh +20 more
2017Nature786 citations Open access
Semantic Scholar
Ionic immune suppression within the tumour microenvironment limits T cell effector function
Robert L. Eil, S. Vodnala, D. Clever, C. Klebanoff +14 more
2016Nature624 citations Open access
Semantic Scholar
T cell stemness and dysfunction in tumors are triggered by a common mechanism
S. Vodnala, Robert L. Eil, R. Kishton, Madhusudhanan Sukumar +15 more
2019Science505 citations Open access
Semantic Scholar
Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence
Laura Vera-Ramirez, S. Vodnala, Ryan Nini, K. Hunter +1 more
2018Nature Communications401 citations Open access
Semantic Scholar
Inhibition of AKT signaling uncouples T cell differentiation from expansion for receptor-engineered adoptive immunotherapy.
C. Klebanoff, Joseph G. Crompton, A. Leonardi, Tori N. Yamamoto +15 more
2017JCI Insight198 citations Open access
Semantic Scholar
Multi-phenotype CRISPR-Cas9 Screen Identifies p38 Kinase as a Target for Adoptive Immunotherapies
Devikala Gurusamy, Amanda N. Henning, Tori N. Yamamoto, Zhi-Ya Yu +14 more
2020Cancer Cell146 citations Open access
Semantic Scholar
T cells genetically engineered to overcome death signaling enhance adoptive cancer immunotherapy
Tori N. Yamamoto, Ping-Hsien Lee, S. Vodnala, Devikala Gurusamy +14 more
2019Journal of Clinical Investigation137 citations Open access
Semantic Scholar
Multimodel preclinical platform predicts clinical response of melanoma to immunotherapy
Eva Pérez-Guijarro, H. Yang, R. Araya, R. El Meskini +21 more
2020Nature Medicine94 citations Open access
Semantic Scholar
Bioluminescent Imaging of Trypanosoma brucei Shows Preferential Testis Dissemination Which May Hamper Drug Efficacy in Sleeping Sickness
F. Claes, S. Vodnala, N. Van Reet, N. Boucher +5 more
2009PLoS Neglected Tropical Diseases91 citations Open access
Semantic Scholar
Host conditioning with IL-1β improves the antitumor function of adoptively transferred T cells
Ping-Hsien Lee, Tori N. Yamamoto, Devikala Gurusamy, Madhusudhanan Sukumar +10 more
2019Journal of Experimental Medicine77 citations Open access
Semantic Scholar
Nitric Oxide Protects against Infection-Induced Neuroinflammation by Preserving the Stability of the Blood-Brain Barrier
G. Olivera, Xiao-Yuan Ren, S. Vodnala, Jun Lu +5 more
2016PLoS Pathogens62 citations Open access
Semantic Scholar
Structure-activity relationships of synthetic cordycepin analogues as experimental therapeutics for African trypanosomiasis.
S. Vodnala, Thomas Lundbäck, Esther Yeheskieli, Birger Sjöberg +7 more
2013Journal of Medicinal Chemistry62 citations
Semantic Scholar
Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade
D. Palmer, Beau R. Webber, Y. Patel, Matthew J. Johnson +34 more
2020bioRxiv57 citations Open access
Semantic Scholar
Distinct Toll-like receptor signals regulate cerebral parasite load and interferon α/β and tumor necrosis factor α-dependent T-cell infiltration in the brains of Trypanosoma brucei-infected mice.
D. N. Amin, S. Vodnala, W. Masocha, Bo Sun +2 more
2012Journal of Infectious Diseases54 citations Open access
Semantic Scholar
Ebsulfur Is a Benzisothiazolone Cytocidal Inhibitor Targeting the Trypanothione Reductase of Trypanosoma brucei *
Jun Lu, S. Vodnala, Anna-Lena Gustavsson, T. Gustafsson +7 more
2013Journal of Biological Chemistry46 citations Open access
Semantic Scholar
Preclinical Assessment of the Treatment of Second-Stage African Trypanosomiasis with Cordycepin and Deoxycoformycin
S. Vodnala, Marcela Ferella, Hilda Lundén-Miguel, E. Betha +7 more
2009PLoS Neglected Tropical Diseases46 citations Open access
Semantic Scholar
Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade
D. Palmer, Beau R. Webber, Yogin Patel, Matthew J. Johnson +34 more
2022i Medicina40 citations Open access
Semantic Scholar
miR-130a and miR-145 reprogram Gr-1+CD11b+ myeloid cells and inhibit tumor metastasis through improved host immunity
Hiroki Ishii, S. Vodnala, B. Achyut, Jae Young So +4 more
2018Nature Communications40 citations Open access
Semantic Scholar
Self-organized yolk sac-like organoids allow for scalable generation of multipotent hematopoietic progenitor cells from induced pluripotent stem cells
Naritaka Tamaoki, Stefan Siebert, T. Maeda, Ngoc-Han Ha +22 more
2021bioRxiv27 citations Open access
Semantic Scholar
Opposing Contributions of Polynucleotide Phosphorylase and the Membrane Protein NlpI to Biofilm Formation by Salmonella enterica Serovar Typhimurium
Syed Fazle Rouf, I. Ahmad, Naeem Anwar, S. Vodnala +3 more
2010Journal of Bacteriology24 citations Open access
Semantic Scholar
Next generation immunotherapy: enhancing stemness of polyclonal T cells to improve anti-tumor activity.
R. Kishton, S. Vodnala, Raul Vizcardo, N. Restifo
2021Current Opinion in Immunology20 citations Open access
Semantic Scholar
Multi-model preclinical platform predicts clinical response of melanoma to immunotherapy
Eva Pérez-Guijarro, H. Yang, R. Araya, R. El Meskini +19 more
2019bioRxiv14 citations Open access
Semantic Scholar
Aicardi-Goutières syndrome gene Rnaseh2c is a metastasis susceptibility gene in breast cancer
Sarah K. Deasy, R. Uehara, S. Vodnala, H. Yang +5 more
2019bioRxiv14 citations Open access
Semantic Scholar
333 Targeting the apical intracellular checkpoint CISH unleashes T cell neoantigen reactivity and effector program
D. Palmer, Beau R. Webber, Y. Patel, Matthew D. Johnson +34 more
2020Journal for ImmunoTherapy of Cancer13 citations Open access
Semantic Scholar
Cancer genes disfavoring T cell immunity identified via integrated systems approach
R. Kishton, Shashank J. Patel, Amy E. Decker, S. Vodnala +18 more
2022Cell Reports12 citations Open access
Semantic Scholar
In Vitro and In Vivo Activities of 2-Aminopyrazines and 2-Aminopyridines in Experimental Models of Human African Trypanosomiasis
S. Vodnala, T. Lundbäck, Birger Sjöberg, R. Svensson +2 more
2012Antimicrobial Agents and Chemotherapy11 citations Open access
Semantic Scholar
Identification of Small Molecule Enhancers of Immunotherapy for Melanoma
Christopher Dextras, Myagmarjav Dashnyam, L. Griner, J. Sundaresan +12 more
2020Scientific Reports8 citations Open access
Semantic Scholar
370 The Epi-RTMtechnology produces a polyclonal TIL product (LYL845) with a greater expansion success rate across hot and cold tumors, improved product phenotype, and maintenance of TCR diversity
Y. Patel, Benjamin Harris, M. Bedard, J. Kritikou +8 more
2022Regular and Young Investigator Award Abstracts4 citations Open access
Semantic Scholar
Abstract 2754: LYL797, a ROR1 CAR T-cell therapy with genetic and epigenetic reprogramming for solid tumors
Spencer Park, Courtney Simianer, Sydney Spadinger, Xiao Wang +22 more
2022Cancer Research3 citations
Semantic Scholar
340 The Epi-RTMtechnology produces a polyclonal TIL product (LYL845) with diverse tumor-reactive clones that have stem-like qualities and anti-tumor function
Benjamin Harris, Y. Patel, Ngoc-Han Ha, Lora Zhao +7 more
2022Regular and Young Investigator Award Abstracts3 citations Open access
Semantic Scholar
Abstract 1527: Integrated computational and experimental analysis identifies the mitochondrial uncoupling protein 2 (Ucp2) as a key regulator of T cell anti-tumor function
Madhusudhanan Sukumar, Kuo-Yuan Cheng, Arunakumar Gangaplara, Y. Patel +13 more
2021Immunology2 citations
Semantic Scholar
Mono-, di- and trisubstituted derivatives of eflornithine: synthesis for in vivo delivery of DL-α-difluoromethyl-ornithine in plasma
Theunis T. Cloete, Carl C Johansson, D. N'Da, S. Vodnala +3 more
2011Arzneimittelforschung2 citations
Semantic Scholar
Abstract 2944: miR-130a and -145 reprogram myeloid derived suppressor cells and enhance anti-tumor immunity
Hiroki Ishii, S. Vodnala, B. Achyut, Christine M. Hollander +2 more
20171 citations
Semantic Scholar
From prediction to engagement: defining tumor-reactive T cells through biological interaction
Nicholas P. Restifo, S. Vodnala, David B. Thompson, Nicholas D. Klemen +2 more
2026bioRxiv0 citations Open access
Semantic Scholar
Aicardi-Goutières Syndrome gene Rnaseh2c is a metastasis susceptibility gene in breast
Sarah K. Deasy, R. Uehara, S. Vodnala, H. Yang +5 more
20230 citations
Semantic Scholar
Abstract A54: Epi-RTM (epigenetic reprogramming) technology improves stemness, preserves polyclonality and enhances antitumor functionality of tumor infiltrating lymphocytes in nonclinical studies
Y. Patel, Ngoc-Han Ha, M. Bedard, J. Kritikou +2 more
2022Cancer immunology research0 citations
Semantic Scholar
Genome-wide profiling of druggable active tumor defense mechanisms to enhance cancer immunotherapy
R. Kishton, Shashank J. Patel, S. Vodnala, Amy E. Decker +15 more
2019bioRxiv0 citations Open access
Semantic Scholar
Abstract 5678: Developing a preclinical immunotherapy platform using syngeneic mouse models of human melanoma
C. Rauck, Eva Pérez-Guijarro, Z. Ohler, R. El Meskini +11 more
2018Immunology0 citations
Semantic Scholar
Abstract 57: Survival of dormant breast cancer cells and metastatic tumor recurrence is dependent upon the activation of autophagy
Laura Vera Ramirez, S. Vodnala, Ryan Nini, K. Hunter +1 more
2018Tumor Biology0 citations
Semantic Scholar
Abstract 5720: Functional characterization of neoantigens determining immune checkpoint blockade response in mouse models of human melanoma
E. Guijarro, Chi-Ping Day, Z. Ohler, R. El Meskini +10 more
2018Immunology0 citations
Semantic Scholar
Peptide-based polymer Toll-Like Receptor 7/8 agonist nanoparticles increase the breadth of anti-tumor CD8 T cell immunity
Andrei Ramirez-Valdez, Nicolas J. Blobel, A. Ishizuka, J. Pan +4 more
2017Journal of Immunology0 citations
Semantic Scholar
Abstract 2623: Identification of neo-antigens driving melanoma response to immune checkpoint blockers viain vivoscreening
Chi-Ping Day, Eva Pérez-Guijarro, R. El Meskini, Z. Ohler +5 more
20170 citations
Semantic Scholar
Abstract 4034: Immunotherapy generates selective pressure to create an escape tumor with increased susceptibility to treatment with T cell based therapies
J. Pan, S. Vodnala, Robert L. Eil, Zhi-Ya Yu +8 more
20160 citations
Semantic Scholar
Abstract 3128: MicroRNA-mediated reprogramming of myeloid cells by targeting TGFβ signaling and its associated molecular network
S. Vodnala
20150 citations
Semantic Scholar
Immunotherapy generates selective pressure for acquisition of immunogenic neoantigens in escape tumors
J. Pan, S. Vodnala, Robert L. Eil, Zhi-Ya Yu +8 more
2015Journal of Immunotherapy for Cancer0 citations Open access
Semantic Scholar
Novel Treatment of African Trypanosomiasis
S. Vodnala
20130 citations
Semantic Scholar
Ebsulfur: a novel Trypanosoma brucei cytocidal inhibitor targeting the trypanothione metabolism
Jun Lu, S. Vodnala, L. Gustavsson, M. Rottenberg +1 more
20120 citations
Semantic Scholar
1 In vitro and In vivo Activity of 2-Aminopyrazines / 2-1 Aminopyridines in Experimental Models of Human African 2 Trypanosomiasis 3
S. Vodnala, Thomas Lundbäck, Birger Sjöberg, R. Svensson +2 more
20120 citations
Semantic Scholar

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N. Restifo×22
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R. Kishton×14
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Shashank J. Patel×11
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Devikala Gurusamy×9

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Robert L. Eil×8

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