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Alejandro P Ugalde · SciRah

Researcher profile · Semantic Scholar

Alejandro P Ugalde

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Alejandro P Ugalde — researcher profile on SciRah

h-index: 22
Works: 36
Citations: 3,440

Most-cited papers

Alternative cleavage and polyadenylation: extent, regulation and function
Ran Elkon, Alejandro P Ugalde, R. Agami
2013Nature reviews genetics771 citations
Semantic Scholar
Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging
I. Varela, Sandrine Pereira, Alejandro P Ugalde, C. Navarro +10 more
2008Nature Medicine422 citations Open access
Semantic Scholar
Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9
Gozde Korkmaz, R. Lopes, Alejandro P Ugalde, E. Nevedomskaya +5 more
2016Nature Biotechnology406 citations
Semantic Scholar
Tumour-specific proline vulnerability uncovered by differential ribosome codon reading
Fabricio Loayza‐Puch, Koos Rooijers, Levi C. M. Buil, Jelle S. Zijlstra +9 more
2016Nature264 citations Open access
Semantic Scholar
Aging and chronic DNA damage response activate a regulatory pathway involving miR‐29 and p53
Alejandro P Ugalde, A. Ramsay, Jorge de la Rosa, I. Varela +5 more
2011EMBO Journal255 citations Open access
Semantic Scholar
Nuclear envelope defects cause stem cell dysfunction in premature-aging mice
J. Espada, I. Varela, Ignacio Flores, Alejandro P Ugalde +7 more
2008Journal of Cell Biology173 citations Open access
Semantic Scholar
Premature aging in mice activates a systemic metabolic response involving autophagy induction.
G. Mariño, Alejandro P Ugalde, Natalia Salvador-Montoliu, I. Varela +5 more
2008Human Molecular Genetics155 citations Open access
Semantic Scholar
Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function
G. Mariño, Alejandro P Ugalde, Álvaro F. Fernández, F. Osorio +3 more
2010Proceedings of the National Academy of Sciences of the United States of America135 citations Open access
Semantic Scholar
SCAF4 and SCAF8, mRNA Anti-Terminator Proteins
L. Gregersen, R. Mitter, Alejandro P Ugalde, Takayuki Nojima +4 more
2019Cell126 citations Open access
Semantic Scholar
3’UTR Shortening Potentiates MicroRNA-Based Repression of Pro-differentiation Genes in Proliferating Human Cells
Yonit Hoffman, D. Bublik, Alejandro P Ugalde, Ran Elkon +4 more
2016PLoS Genetics85 citations Open access
Semantic Scholar
The miR-424(322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland
David Llobet-Navás, R. Rodríguez-Barrueco, Verónica Castro, Alejandro P Ugalde +17 more
2014Genes & Development75 citations Open access
Semantic Scholar
The microRNA-29/PGC1α regulatory axis is critical for metabolic control of cardiac function
Xurde M. Caravia, Víctor Fanjul, Eduardo Oliver, David Roiz-Valle +16 more
2018PLoS Biology70 citations Open access
Semantic Scholar
SLC1A3 contributes to L‐asparaginase resistance in solid tumors
Jian-Hui Sun, Remco Nagel, E. Zaal, Alejandro P Ugalde +11 more
2019EMBO Journal69 citations Open access
Semantic Scholar
Functional CRISPR screen identifies AP1-associated enhancer regulating FOXF1 to modulate oncogene-induced senescence
Rui-Qi Han, Li Li, Alejandro P Ugalde, A. Tal +5 more
2018Genome Biology58 citations Open access
Semantic Scholar
Genome-Wide Polyadenylation Maps Reveal Dynamic mRNA 3'-End Formation in the Failing Human Heart.
E. Creemers, A. Bawazeer, Alejandro P Ugalde, H. W. V. van Deutekom +10 more
2016Circulation Research50 citations Open access
Semantic Scholar
LncRNA-OIS1 regulates DPP4 activation to modulate senescence induced by RAS
Li Li, Pieter C. van Breugel, Fabricio Loayza‐Puch, Alejandro P Ugalde +16 more
2018Nucleic Acids Research48 citations Open access
Semantic Scholar
Metalloproteases and the degradome.
Alejandro P Ugalde, G. Ordóñez, Pedro M. Quirós, X. Puente +1 more
2010Methods in molecular biology45 citations Open access
Semantic Scholar
Identification of Human Aminopeptidase O, a Novel Metalloprotease with Structural Similarity to Aminopeptidase B and Leukotriene A4 Hydrolase*
A. Díaz-Perales, V. Quesada, L. M. Sánchez, Alejandro P Ugalde +3 more
2005Journal of Biological Chemistry42 citations Open access
Semantic Scholar
Autophagy‐linked plasma and lysosomal membrane protein PLAC8 is a key host factor for SARS‐CoV‐2 entry into human cells
Alejandro P Ugalde, G. Bretones, David Rodríguez, V. Quesada +15 more
2022EMBO Journal31 citations Open access
Semantic Scholar
Micromanaging aging with miRNAs
Alejandro P Ugalde, Y. Español, C. López-Otín
2011The Nucleus29 citations Open access
Semantic Scholar
Identification and Characterization of Human Archaemetzincin-1 and -2, Two Novel Members of a Family of Metalloproteases Widely Distributed in Archaea*
A. Díaz-Perales, V. Quesada, J. Peinado, Alejandro P Ugalde +4 more
2005Journal of Biological Chemistry29 citations Open access
Semantic Scholar
Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair
Michal Gavish-Izakson, Bhagya Bhavana Velpula, Ran Elkon, Rosario Prados-Carvajal +7 more
2017Nucleic Acids Research22 citations Open access
Semantic Scholar
Cell autonomous and systemic factors in progeria development.
F. Osorio, Alejandro P Ugalde, G. Mariño, X. Puente +2 more
2011Biochemical Society Transactions22 citations Open access
Semantic Scholar
A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis
Li Li, Alejandro P Ugalde, C. Scheele, S. Dieter +18 more
2021Genome Biology19 citations Open access
Semantic Scholar
Rejuvenating somatotropic signaling: a therapeutical opportunity for premature aging?
Alejandro P Ugalde, G. Mariño, C. López-Otín
2010Aging16 citations Open access
Semantic Scholar
TGFβ1‐induced leucine limitation uncovered by differential ribosome codon reading
Fabricio Loayza-Puch, Koos Rooijers, Jelle S. Zijlstra, Behzad Moumbeini +6 more
2017EMBO Reports11 citations Open access
Semantic Scholar
Correction: 3'UTR Shortening Potentiates MicroRNA-Based Repression of Pro-differentiation Genes in Proliferating Human Cells
Alejandro P Ugalde
2016PLoS Genetics11 citations Open access
Semantic Scholar
The Emergence of GeroMIRs: A Group of MicroRNAs Implicated in Aging
Alejandro P Ugalde, Agnieszka Kwarciak, Xurde M. Caravia, C. López-Otín +1 more
20134 citations
Semantic Scholar
Identification of Human Aminopeptidase O, a Novel Metalloprotease with Structural Similarity to Aminopeptidase B and Leukotriene a 4 Hydrolase*
A. Díaz-Perales, Víctor Quesada, L. M. Sánchez, Alejandro P Ugalde +6 more
3 citations
Semantic Scholar
Host factor PLAC8 is required for pancreas infection by SARS-CoV-2
Lesly Ibargüen-González, S. Heller, Darío López-García, Hanna Dietenberger +13 more
2025Communications Medicine1 citations Open access
Semantic Scholar
Current advances and future prospects of cell reprogramming in progeroid syndromes
Lucas Moledo-Nodar, Víctor Celemín-Capaldi, Alejandro P Ugalde, J. Freije
2025Frontiers in Cell and Developmental Biology1 citations Open access
Semantic Scholar
Withdrawal: Identification of human aminopeptidase O, a novel metalloprotease with structural similarity to aminopeptidase B and leukotriene A4 hydrolase.
A. Díaz-Perales, V. Quesada, L. M. Sánchez, Alejandro P Ugalde +3 more
2019Journal of Biological Chemistry0 citations Open access
Semantic Scholar
Withdrawal: Identification and characterization of human archaemetzincin-1 and -2, two novel members of a family of metalloproteases widely distributed in Archaea.
A. Díaz-Perales, V. Quesada, J. Peinado, Alejandro P Ugalde +4 more
2019Journal of Biological Chemistry0 citations Open access
Semantic Scholar
epithelium in the involuting mammary gland cluster orchestrates remodeling of the miR-424 ( 322 ) / 503 The Material Supplemental
David Llobet-Navás, R. Rodríguez-Barrueco, Verónica Castro, Alejandro P Ugalde +17 more
20140 citations
Semantic Scholar
Chapter 88 – Aminopeptidase O
Alejandro P Ugalde
20130 citations
Semantic Scholar
Aging and DNA-damage response activate a regulatory pathway involving miR-29 and p 53
Alejandro P Ugalde, A. Ramsay, Jorge de la Rosa, I. Varela +5 more
20110 citations
Semantic Scholar

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