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R. Agami · SciRah

Researcher profile · Semantic Scholar

R. Agami

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R. Agami — researcher profile on SciRah

h-index: 68
Works: 190
Citations: 27K

Most-cited papers

Alternative cleavage and polyadenylation: extent, regulation and function
Ran Elkon, Alejandro P Ugalde, R. Agami
2013Nature reviews genetics771 citations
Semantic Scholar
eRNAs are required for p53-dependent enhancer activity and gene transcription.
C. Melo, J. Drost, Patrick J. Wijchers, H. V. D. van de Werken +8 more
2013Molecules and Cells525 citations Open access
Semantic Scholar
Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9
Gozde Korkmaz, R. Lopes, Alejandro P Ugalde, E. Nevedomskaya +5 more
2016Nature Biotechnology406 citations
Semantic Scholar
Transcription Impacts the Efficiency of mRNA Translation via Co-transcriptional N6-adenosine Methylation
B. Slobodin, Rui-Qi Han, V. Calderone, Joachim A. F. Oude Vrielink +3 more
2017Cell399 citations Open access
Semantic Scholar
Tumour-specific proline vulnerability uncovered by differential ribosome codon reading
Fabricio Loayza‐Puch, Koos Rooijers, Levi C. M. Buil, Jelle S. Zijlstra +9 more
2016Nature264 citations Open access
Semantic Scholar
Altered microRNA expression associated with chromosomal changes contributes to cervical carcinogenesis
S. Wilting, P. J. Snijders, W. Verlaat, A. Jaspers +9 more
2013Oncogene178 citations
Semantic Scholar
MIR181A regulates starvation- and rapamycin-induced autophagy through targeting of ATG5
Kumsal Tekirdag, Gozde Korkmaz, D. Ozturk, R. Agami +1 more
2013Autophagy174 citations Open access
Semantic Scholar
Genome-wide profiling of p53-regulated enhancer RNAs uncovers a subset of enhancers controlled by a lncRNA
Nicolas Léveillé, C. Melo, Koos Rooijers, Á. Díaz-Lagares +12 more
2015Nature Communications172 citations Open access
Semantic Scholar
E2F mediates enhanced alternative polyadenylation in proliferation
Ran Elkon, J. Drost, G. van Haaften, Mathias Jenal +3 more
2012Genome Biology154 citations Open access
Semantic Scholar
Anti-tumour immunity induces aberrant peptide presentation in melanoma
O. Bartok, Abhijeet Pataskar, Remco Nagel, Maarja Laos +26 more
2020Nature148 citations Open access
Semantic Scholar
DNA damage induces p53-independent apoptosis through ribosome stalling
Nicolaas J. Boon, Rafaela A. Oliveira, Pierré-René Körner, Adva Kochavi +14 more
2024Science146 citations Open access
Semantic Scholar
BRCA1185delAG tumors may acquire therapy resistance through expression of RING-less BRCA1.
R. Drost, Kiranjit K. Dhillon, H. van der Gulden, I. van der Heijden +25 more
2016Journal of Clinical Investigation131 citations Open access
Semantic Scholar
Tryptophan depletion results in tryptophan-to-phenylalanine substitutants
Abhijeet Pataskar, Julien Champagne, Remco Nagel, J. Kenski +20 more
2022Nature129 citations Open access
Semantic Scholar
Oncogenic miR-181a/b affect the DNA damage response in aggressive breast cancer
A. Bisso, M. Faleschini, Federico Zampa, Valeria Capaci +7 more
2013Cell Cycle128 citations Open access
Semantic Scholar
SCAF4 and SCAF8, mRNA Anti-Terminator Proteins
L. Gregersen, R. Mitter, Alejandro P Ugalde, Takayuki Nojima +4 more
2019Cell126 citations Open access
Semantic Scholar
miR-155 drives telomere fragility in human breast cancer by targeting TRF1.
Roberto Dinami, Cristiana Ercolani, E. Petti, S. Piazza +11 more
2014Cancer Research119 citations Open access
Semantic Scholar
p53 induces transcriptional and translational programs to suppress cell proliferation and growth
Fabricio Loayza‐Puch, J. Drost, Koos Rooijers, R. Lopes +2 more
2013Genome Biology113 citations Open access
Semantic Scholar
Alternative Cleavage and Polyadenylation during Colorectal Cancer Development
A. Morris, Arnold J. Bos, B. Diosdado, Koos Rooijers +5 more
2012Clinical Cancer Research112 citations Open access
Semantic Scholar
Ribosome profiling reveals features of normal and disease-associated mitochondrial translation
Koos Rooijers, Fabricio Loayza‐Puch, L. Nijtmans, R. Agami
2013Nature Communications97 citations Open access
Semantic Scholar
Characterization of noncoding regulatory DNA in the human genome
Ran Elkon, R. Agami
2017Nature Biotechnology90 citations
Semantic Scholar
Noncoding RNAs and cancer.
J. Lieberman, F. Slack, P. Pandolfi, A. Chinnaiyan +2 more
2013Cell88 citations Open access
Semantic Scholar
3’UTR Shortening Potentiates MicroRNA-Based Repression of Pro-differentiation Genes in Proliferating Human Cells
Yonit Hoffman, D. Bublik, Alejandro P Ugalde, Ran Elkon +4 more
2016PLoS Genetics85 citations Open access
Semantic Scholar
Methylation-mediated transcriptional repression of microRNAs during cervical carcinogenesis
S. Wilting, W. Verlaat, A. Jaspers, Nour A. Makazaji +4 more
2013Epigenetics79 citations Open access
Semantic Scholar
SLC1A3 contributes to L‐asparaginase resistance in solid tumors
Jian-Hui Sun, Remco Nagel, E. Zaal, Alejandro P Ugalde +11 more
2019EMBO Journal69 citations Open access
Semantic Scholar
Transcription Dynamics Regulate Poly(A) Tails and Expression of the RNA Degradation Machinery to Balance mRNA Levels.
B. Slobodin, A. Bahat, Urmila Sehrawat, Shirly Becker-Herman +8 more
2020Molecules and Cells68 citations Open access
Semantic Scholar
Translatome analysis reveals altered serine and glycine metabolism in T-cell acute lymphoblastic leukemia cells
K. Kampen, L. Fancello, Tiziana Girardi, Gianmarco Rinaldi +15 more
2019Nature Communications63 citations Open access
Semantic Scholar
Applying CRISPR–Cas9 tools to identify and characterize transcriptional enhancers
R. Lopes, Gozde Korkmaz, R. Agami
2016Nature reviews. Molecular cell biology63 citations
Semantic Scholar
Functional CRISPR screen identifies AP1-associated enhancer regulating FOXF1 to modulate oncogene-induced senescence
Rui-Qi Han, Li Li, Alejandro P Ugalde, A. Tal +5 more
2018Genome Biology58 citations Open access
Semantic Scholar
Long non-coding RNAs in metastasis
Qi-Hong Huang, Jinchun Yan, R. Agami
2017Cancer Metastasis Review54 citations
Semantic Scholar
FcαRI co-stimulation converts human intestinal CD103+ dendritic cells into pro-inflammatory cells through glycolytic reprogramming
I. S. Hansen, L. Krabbendam, J. Bernink, Fabricio Loayza-Puch +14 more
2018Nature Communications51 citations Open access
Semantic Scholar
Oncogene-dependent sloppiness in mRNA translation.
Julien Champagne, Abhijeet Pataskar, N. Blommaert, Remco Nagel +10 more
2021Molecules and Cells50 citations Open access
Semantic Scholar
Genome-Wide Polyadenylation Maps Reveal Dynamic mRNA 3'-End Formation in the Failing Human Heart.
E. Creemers, A. Bawazeer, Alejandro P Ugalde, H. W. V. van Deutekom +10 more
2016Circulation Research50 citations Open access
Semantic Scholar
Proteomic patterns associated with response to breast cancer neoadjuvant treatment
Anjana Shenoy, Nishanth Belugali Nataraj, G. Perry, Fabricio Loayza Puch +11 more
2020Molecular Systems Biology49 citations Open access
Semantic Scholar
LncRNA-OIS1 regulates DPP4 activation to modulate senescence induced by RAS
Li Li, Pieter C. van Breugel, Fabricio Loayza‐Puch, Alejandro P Ugalde +16 more
2018Nucleic Acids Research48 citations Open access
Semantic Scholar
GRO-seq, A Tool for Identification of Transcripts Regulating Gene Expression.
R. Lopes, R. Agami, Gozde Korkmaz
2017Methods in molecular biology43 citations
Semantic Scholar
Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers
Tom Van Nyen, M. Planque, L. van Wagensveld, J. Duarte +21 more
2022Nature Communications42 citations Open access
Semantic Scholar
A fragment-like approach to PYCR1 inhibition.
Kirsty Milne, Jian-Hui Sun, E. Zaal, J. Mowat +7 more
2019Bioorganic & Medicinal Chemistry Letters33 citations Open access
Semantic Scholar
Enhancer-associated RNAs as therapeutic targets
Nicolas Léveillé, C. Melo, R. Agami
2015Expert Opinion on Biological Therapy33 citations Open access
Semantic Scholar
Arginine deprivation enriches lung cancer proteomes with cysteine by inducing arginine-to-cysteine substitutants
Chao Yang, Abhijeet Pataskar, Xiao-Dong Feng, Jasmine Montenegro Navarro +6 more
2024Molecules and Cells32 citations Open access
Semantic Scholar
An adverse tumor-protective effect of IDO1 inhibition
J. Kenski, Xin-Yao Huang, David W. Vredevoogd, B. de Bruijn +19 more
2023Cell Reports Medicine31 citations Open access
Semantic Scholar
A p53-bound enhancer region controls a long intergenic noncoding RNA required for p53 stress response
C. Melo, N. Léveillé, K. Rooijers, PJ Wijchers +5 more
2016Oncogene27 citations Open access
Semantic Scholar
The phosphatase inhibitor LB-100 creates neoantigens in colon cancer cells through perturbation of mRNA splicing
M. H. Dias, Vladyslava Liudkovska, Jasmine Montenegro Navarro, Lisanne Giebel +7 more
2024EMBO Reports26 citations Open access
Semantic Scholar
Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma
Najla El Hachem, Marine Leclercq, Miguel Susaeta Ruiz, Raphael Vanleyssem +19 more
2024Nature Cell Biology26 citations Open access
Semantic Scholar
A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation
Gozde Korkmaz, Zohar Manber, R. Lopes, S. Preković +9 more
2019Nucleic Acids Research24 citations Open access
Semantic Scholar
Proteome diversification by mRNA translation in cancer.
Adva Kochavi, Domenica Lovecchio, W. Faller, R. Agami
2022Molecules and Cells23 citations Open access
Semantic Scholar
Exposure to arginine analog canavanine induces aberrant mitochondrial translation products, mitoribosome stalling, and instability of the mitochondrial proteome.
S. Konovalova, T. Hilander, Fabricio Loayza‐Puch, Koos Rooijers +2 more
2015International Journal of Biochemistry and Cell Biology23 citations
Semantic Scholar
Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair
Michal Gavish-Izakson, Bhagya Bhavana Velpula, Ran Elkon, Rosario Prados-Carvajal +7 more
2017Nucleic Acids Research22 citations Open access
Semantic Scholar
MYC is a clinically significant driver of mTOR inhibitor resistance in breast cancer
J. Bhin, Julia Yemelyanenko, Xue Chao, S. Klarenbeek +20 more
2023Journal of Experimental Medicine21 citations Open access
Semantic Scholar
Alternative cleavage and polyadenylation generates downstream uncapped RNA isoforms with translation potential
Y. Malka, F. Alkan, Shinyeong Ju, Pierré-René Körner +9 more
2022Molecules and Cells21 citations Open access
Semantic Scholar
Slippy-Sloppy translation: a tale of programmed and induced-ribosomal frameshifting.
Julien Champagne, Kelly Mordente, Remco Nagel, R. Agami
2022Trends in Genetics20 citations Open access
Semantic Scholar

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Alejandro P Ugalde×10
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Fabricio Loayza‐Puch×10
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Gozde Korkmaz — researcher profile on SciRah

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E. Zaal — researcher profile on SciRah