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G. Bretones · SciRah

Researcher profile · Semantic Scholar

G. Bretones

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G. Bretones — researcher profile on SciRah

h-index: 19
Works: 39
Citations: 1,678

Most-cited papers

Myc and cell cycle control.
G. Bretones, M. Delgado, J. León
2015Biochimica et Biophysica Acta692 citations Open access
Semantic Scholar
Giant tortoise genomes provide insights into longevity and age-related disease
V. Quesada, Sandra Freitas-Rodríguez, J. Miller, J. Pérez-Silva +31 more
2018Nature Ecology & Evolution108 citations Open access
Semantic Scholar
SKP2 Oncogene Is a Direct MYC Target Gene and MYC Down-regulates p27KIP1 through SKP2 in Human Leukemia Cells*
G. Bretones, Juan C. Acosta, J. M. Caraballo, N. Ferrandiz +8 more
2011Journal of Biological Chemistry95 citations Open access
Semantic Scholar
Myc stimulates cell cycle progression through the activation of Cdk1 and phosphorylation of p27
Lucía García-Gutiérrez, G. Bretones, Ester Molina, I. Arechaga +9 more
2018Scientific Reports68 citations Open access
Semantic Scholar
Altered patterns of global protein synthesis and translational fidelity in RPS15-mutated chronic lymphocytic leukemia.
G. Bretones, M. Alvarez, Javier R. Arango, David Rodríguez +13 more
2018Blood66 citations Open access
Semantic Scholar
Mutations in CHD2 cause defective association with active chromatin in chronic lymphocytic leukemia.
David Rodríguez, G. Bretones, V. Quesada, N. Villamor +10 more
2015Blood63 citations Open access
Semantic Scholar
MYC antagonizes the differentiation induced by imatinib in chronic myeloid leukemia cells through downregulation of p27KIP1
M. Gómez-Casares, E. García-Alegría, C. E. López-Jorge, N. Ferrandiz +10 more
2013Oncogene63 citations Open access
Semantic Scholar
Myc Inhibits p27-Induced Erythroid Differentiation of Leukemia Cells by Repressing Erythroid Master Genes without Reversing p27-Mediated Cell Cycle Arrest
Juan C. Acosta, N. Ferrandiz, G. Bretones, V. Torrano +6 more
2008Molecular and Cellular Biology59 citations Open access
Semantic Scholar
Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes.
V. Bhaskar, A. Graff-Meyer, A. Schenk, S. Cavadini +7 more
2020Cell Reports57 citations Open access
Semantic Scholar
Transcription Factors Sp1 and p73 Control the Expression of the Proapoptotic Protein NOXA in the Response of Testicular Embryonal Carcinoma Cells to Cisplatin*
Lara Grande, G. Bretones, M. Rosa-Garrido, E. M. Garrido-Martin +9 more
2012Journal of Biological Chemistry53 citations Open access
Semantic Scholar
p21 as a Transcriptional Co-Repressor of S-Phase and Mitotic Control Genes
N. Ferrandiz, J. M. Caraballo, Lucía García-Gutiérrez, Vikram Devgan +11 more
2012PLoS ONE50 citations Open access
Semantic Scholar
Circulating tumor cells for comprehensive and multiregional non-invasive genetic characterization of multiple myeloma
J. Garcés, G. Bretones, L. Burgos, R. Valdés-Mas +29 more
2020Leukemia45 citations Open access
Semantic Scholar
c-Myc Inhibits Ras-Mediated Differentiation of Pheochromocytoma Cells by Blocking c-Jun Up-Regulation
J. Vaqué, B. Fernández-García, P. García-Sanz, N. Ferrandiz +5 more
2008Molecular Cancer Research42 citations Open access
Semantic Scholar
Comparative genomics of mortal and immortal cnidarians unveils novel keys behind rejuvenation
Maria Pascual-Torner, Dido Carrero, J. Pérez-Silva, Diana Álvarez-Puente +10 more
2022Proceedings of the National Academy of Sciences of the United States of America40 citations Open access
Semantic Scholar
Autophagy‐linked plasma and lysosomal membrane protein PLAC8 is a key host factor for SARS‐CoV‐2 entry into human cells
Alejandro P Ugalde, G. Bretones, David Rodríguez, V. Quesada +15 more
2022EMBO Journal31 citations Open access
Semantic Scholar
High p27 protein levels in chronic lymphocytic leukemia are associated to low Myc and Skp2 expression, confer resistance to apoptosis and antagonize Myc effects on cell cycle
J. M. Caraballo, Juan C. Acosta, M. A. Cortés, M. Albajar +9 more
2014OncoTarget24 citations Open access
Semantic Scholar
ATG4D is the main ATG8 delipidating enzyme in mammalian cells and protects against cerebellar neurodegeneration
Isaac Tamargo-Gómez, Gemma G. Martínez-García, M-Falero B. Suarez, V. Rey +14 more
2021Cell Death and Differentiation22 citations Open access
Semantic Scholar
Molecular pathogenesis of CLL and its evolution
David Rodríguez, G. Bretones, Javier R. Arango, Victor M. Valdespino +3 more
2015International journal of hematology21 citations Open access
Semantic Scholar
MYC accelerates p21CIP‐induced megakaryocytic differentiation involving early mitosis arrest in leukemia cells
María J. Muñoz-Alonso, L. Ceballos, G. Bretones, Pilar Frade +2 more
2012Journal of Cellular Physiology21 citations
Semantic Scholar
The MNT transcription factor autoregulates its expression and supports proliferation in MYC-associated factor X (MAX)-deficient cells
M. Lafita-Navarro, J. Liaño-Pons, A. Quintanilla, I. Varela +12 more
2020Journal of Biological Chemistry15 citations Open access
Semantic Scholar
CD3ε recruits Numb to promote TCR degradation.
N. Martín-Blanco, Daniel Jiménez Teja, G. Bretones, A. Borroto +5 more
2016International Immunology13 citations Open access
Semantic Scholar
Analysis of ATG4C function in vivo
Isaac Tamargo-Gómez, Gemma G. Martínez-García, M-Falero B. Suarez, Pablo Mayoral +8 more
2023Autophagy10 citations Open access
Semantic Scholar
Mutations in CHD 2 cause defective association with active chromatin in chronic lymphocytic leukemia
David Rodríguez, G. Bretones, V. Quesada, N. Villamor +10 more
20158 citations
Semantic Scholar
The Mithralog EC-7072 Induces Chronic Lymphocytic Leukemia Cell Death by Targeting Tonic B-Cell Receptor Signaling
Seila Lorenzo-Herrero, Christian Sordo-Bahamonde, G. Bretones, Á. Payer +8 more
2019Frontiers in Immunology5 citations Open access
Semantic Scholar
Genomic Profiles of Bone Marrow (BM) Clonal Plasma Cells (PCs) Vs Circulating Tumor Cells (CTCs) and Extramedullary (EM) Plasmacytomas in Multiple Myeloma (MM)
G. Bretones, B. Paiva, R. Valdés-Mas, D. Alignani +7 more
20165 citations
Semantic Scholar
USP49 deubiquitinase regulates the mitotic spindle checkpoint and prevents aneuploidy
Diana Campos-Iglesias, Julia M. Fraile, G. Bretones, A. Montero +4 more
2023Cell Death and Disease2 citations Open access
Semantic Scholar
Host factor PLAC8 is required for pancreas infection by SARS-CoV-2
Lesly Ibargüen-González, S. Heller, Darío López-García, Hanna Dietenberger +13 more
2025Communications Medicine1 citations Open access
Semantic Scholar
Circulating Tumor Cells (CTCs) for Comprehensive and Multiregional Non-Invasive Genetic Characterization of Multiple Myeloma (MM)
J. Garcés, G. Bretones, L. Burgos, R. Valdés-Mas +23 more
2019Blood1 citations Open access
Semantic Scholar
Myc-dependent cell cycle progression through the activation of CDK1 and phosphorylation of p27
Lucía García-Gutiérrez, G. Bretones, I. Arechaga, David Santamaría +2 more
20161 citations
Semantic Scholar
Abstract 3080: MYC antagonizes imatinib-induced differentiation in chronic myeloid leukemia cells through downregulation of p27KIP1
J. León, M. Gómez-Casares, N. Ferrandiz, C. López +5 more
20121 citations
Semantic Scholar
Correction for Pascual-Torner et al., Comparative genomics of mortal and immortal cnidarians unveils novel keys behind rejuvenation
Maria Pascual-Torner, Dido Carrero, J. Pérez-Silva, Diana Álvarez-Puente +10 more
2023Proceedings of the National Academy of Sciences of the United States of America0 citations Open access
Semantic Scholar
Correction to: ATG4D is the main ATG8 delipidating enzyme in mammalian cells and protects against cerebellar neurodegeneration
Isaac Tamargo-Gómez, Gemma G. Martínez-García, M-Falero B. Suarez, V. Rey +14 more
2021Cell Death and Differentiation0 citations Open access
Semantic Scholar
The MYC antagonist MNT autoregulates its expression and supports proliferation in MAX deficient cells
M. Lafita-Navarro, J. Liaño-Pons, A. Quintanilla, I. Varela +9 more
2017bioRxiv0 citations Open access
Semantic Scholar
304: Myc mediates the phosphorylation and degradation of p27 through activation of Cyclin A/CDK1
Lucía García-Gutiérrez, G. Bretones, I. Arechaga, David Santamaría +2 more
20140 citations
Semantic Scholar
Induction of p27 degradation by Myc through CyclinA/CDK1 complexes
Lucía García-Gutiérrez, G. Bretones, I. Arechaga, David Santamaría +2 more
20140 citations
Semantic Scholar
358 MYC Impairs the Differentiation but not the Growth Arrest Induced by Bcr-Abl Inhibitors in Chronic Myelouid Leukemia Cells Through P27KIP1 Down-regulation
E. Alegría, M. Gómez-Casares, C. E. López Jorge, N. Ferrandiz +6 more
20120 citations
Semantic Scholar
669 P21WAF1 Represses Cell Cycle Genes in K562 Cells Acting as a Transcriptional Modulator
L. García, N. Ferrandiz, J. M. Caraballo, M. Lafita +6 more
20120 citations Open access
Semantic Scholar
661 SKP2 oncogene is a MYC target gene in human leukemia cells
J. León, G. Bretones, J. Acosta, J. M. Caraballo +3 more
20100 citations Open access
Semantic Scholar
MYC inhibition of p27-induced erythroid differentiation is mediated by the repression of erythroid master genes and uncoupled from its cell cycle promoting activity
N. Ferrandiz, J. Acosta, G. Bretones, V. Torrano +6 more
20080 citations
Semantic Scholar

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J. León×20
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C. López-Otín×15
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M. Delgado×10
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N. Ferrandiz×10
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J. M. Caraballo×7

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David Rodríguez×7

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Javier R. Arango×5

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