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C. Yapp · SciRah

Researcher profile · Semantic Scholar

C. Yapp

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C. Yapp — researcher profile on SciRah

h-index: 35
Works: 89
Citations: 5,592

Most-cited papers

Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes
Jia-Ren Lin, Benjamin Izar, Shu Wang, C. Yapp +4 more
2018eLife623 citations Open access
Semantic Scholar
The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution
O. Rozenblatt-Rosen, A. Regev, Philipp Oberdoerffer, T. Nawy +362 more
2020Cell514 citations Open access
Semantic Scholar
Immuno-SABER enables highly multiplexed and amplified protein imaging in tissues
Sinem K. Saka, Yu Wang, Jocelyn Y. Kishi, Allen Zhu +14 more
2019Nature Biotechnology435 citations Open access
Semantic Scholar
Multiplexed 3D atlas of state transitions and immune interaction in colorectal cancer
Jia-Ren Lin, Shu Wang, S. Coy, Yu-An Chen +7 more
2023Cell274 citations Open access
Semantic Scholar
Discovery and Optimization of Small-Molecule Ligands for the CBP/p300 Bromodomains
D. Hay, O. Fedorov, Sarah Martin, Dean C. Singleton +16 more
2014Journal of the American Chemical Society272 citations Open access
Semantic Scholar
Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer
A. Färkkilä, D. Gulhan, J. Casado, C. Jacobson +23 more
2020Nature Communications256 citations Open access
Semantic Scholar
Inflammation activation and resolution in human tendon disease
S. Dakin, F. Martínez, C. Yapp, G. Wells +7 more
2015Science Translational Medicine234 citations Open access
Semantic Scholar
MCMICRO: A scalable, modular image-processing pipeline for multiplexed tissue imaging
D. Schapiro, A. Sokolov, C. Yapp, Yu-An Chen +23 more
2021Nature Methods227 citations Open access
Semantic Scholar
Pathogenic variants damage cell composition and single cell transcription in cardiomyopathies
D. Reichart, E. Lindberg, H. Maatz, A. Miranda +50 more
2022Science208 citations Open access
Semantic Scholar
Generation of a selective small molecule inhibitor of the CBP/p300 bromodomain for leukemia therapy
S. Picaud, O. Fedorov, A. Thanasopoulou, K. Leonards +33 more
2015Cancer Research202 citations Open access
Semantic Scholar
The spatial landscape of progression and immunoediting in primary melanoma at single cell resolution
A. J. Nirmal, Z. Maliga, Tuulia Vallius, B. Quattrochi +10 more
2021bioRxiv187 citations Open access
Semantic Scholar
High-plex immunofluorescence imaging and traditional histology of the same tissue section for discovering image-based biomarkers
Jia-Ren Lin, Yu-An Chen, Daniel Campton, J. Cooper +10 more
2023Nature Cancer157 citations Open access
Semantic Scholar
5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation
R. Hopkinson, A. Tumber, C. Yapp, R. Chowdhury +27 more
2013Chemical Science152 citations Open access
Semantic Scholar
Stitching and registering highly multiplexed whole-slide images of tissues and tumors using ASHLAR
J. Muhlich, Yu-An Chen, C. Yapp, Douglas Russell +2 more
2021bioRxiv149 citations Open access
Semantic Scholar
Highly selective inhibition of histone demethylases by de novo macrocyclic peptides
A. Kawamura, M. Münzel, T. Kojima, C. Yapp +15 more
2017Nature Communications126 citations Open access
Semantic Scholar
Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells
A. Tumber, A. Nuzzi, E. Hookway, S. Hatch +24 more
2017Cell Chemical Biology114 citations Open access
Semantic Scholar
Pan-histone demethylase inhibitors simultaneously targeting Jumonji C and lysine-specific demethylases display high anticancer activities.
D. Rotili, Stefano Tomassi, M. Conte, R. Benedetti +15 more
2014Journal of Medicinal Chemistry112 citations Open access
Semantic Scholar
HSF1 phase transition mediates stress adaptation and cell fate decisions
Giorgio Gaglia, R. Rashid, C. Yapp, Gaurav N. Joshi +6 more
2020Nature Cell Biology100 citations Open access
Semantic Scholar
Single cell spatial analysis reveals the topology of immunomodulatory purinergic signaling in glioblastoma
S. Coy, Shu Wang, S. Stopka, Jia-Ren Lin +19 more
2022Nature Communications91 citations Open access
Semantic Scholar
[1,2,4]Triazolo[4,3-a]phthalazines: Inhibitors of Diverse Bromodomains
O. Fedorov, Hannah Lingard, C. Wells, Octovia P. Monteiro +11 more
2013Journal of Medicinal Chemistry85 citations Open access
Semantic Scholar
MITI Minimum Information guidelines for highly multiplexed tissue images
D. Schapiro, C. Yapp, A. Sokolov, S. Reynolds +34 more
2021Nature Methods78 citations Open access
Semantic Scholar
Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching
M. Philpott, Catherine Rogers, C. Yapp, C. Wells +6 more
2014Epigenetics & Chromatin72 citations Open access
Semantic Scholar
Identification and Development of 2,3-Dihydropyrrolo[1,2-a]quinazolin-5(1H)-one Inhibitors Targeting Bromodomains within the Switch/Sucrose Nonfermenting Complex
Charlotte L. Sutherell, C. Tallant, Octovia P. Monteiro, C. Yapp +8 more
2016Journal of Medicinal Chemistry59 citations Open access
Semantic Scholar
Control of synaptic specificity by establishing a relative preference for synaptic partners
Chun-Di Xu, Emma K. Theisen, R. Maloney, Jing Peng +15 more
2019Neuron54 citations Open access
Semantic Scholar
HELZ2 Is an IFN Effector Mediating Suppression of Dengue Virus
D. Fusco, Henry E. Pratt, Stephen Kandilas, Scarlett Se Yun Cheon +14 more
2017Frontiers in Microbiology52 citations Open access
Semantic Scholar
Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 severity
Z. Inde, B. Croker, C. Yapp, Gaurav N. Joshi +27 more
2021Science Advances49 citations Open access
Semantic Scholar
UnMICST: Deep learning with real augmentation for robust segmentation of highly multiplexed images of human tissues
C. Yapp, Edward Novikov, Won-Dong Jang, Tuulia Vallius +8 more
2021bioRxiv48 citations Open access
Semantic Scholar
The Mechanical, Structural, and Compositional Changes of Tendon Exposed to Elastase
T. Grant, C. Yapp, Qi Chen, J. Czernuszka +1 more
2015Annals of Biomedical Engineering47 citations
Semantic Scholar
Spatial intra-tumor heterogeneity is associated with survival of lung adenocarcinoma patients
Hua-Jun Wu, D. Temko, Z. Maliga, A. Moreira +14 more
2022Cell Genomics46 citations Open access
Semantic Scholar
The response of tenocytes to commercial scaffolds used for rotator cuff repair.
R. Smith, Andrew Carr, S. Dakin, Sarah J B Snelling +2 more
2016European Cells & Materials45 citations Open access
Semantic Scholar
Assessing histone demethylase inhibitors in cells: lessons learned
S. Hatch, C. Yapp, R. Montenegro, P. Savitsky +23 more
2017Epigenetics & Chromatin42 citations Open access
Semantic Scholar
Highly multiplexed immunofluorescence images and single-cell data of immune markers in tonsil and lung cancer
R. Rashid, Giorgio Gaglia, Yu-An Chen, Jia-Ren Lin +8 more
2019Scientific Data41 citations Open access
Semantic Scholar
H3K27me3 demethylases regulate in vitro chondrogenesis and chondrocyte activity in osteoarthritis
C. Yapp, A. Carr, A. Price, U. Oppermann +1 more
2016Arthritis Research & Therapy39 citations Open access
Semantic Scholar
Selective Targeting of Bromodomains of the Bromodomain-PHD Fingers Family Impairs Osteoclast Differentiation
J. Meier, C. Tallant, O. Fedorov, H. Witwicka +23 more
2017ACS Chemical Biology38 citations Open access
Semantic Scholar
Discovery of a Highly Selective Cell‐Active Inhibitor of the Histone Lysine Demethylases KDM2/7
P. Gerken, Jamie R. Wolstenhulme, A. Tumber, S. Hatch +16 more
2017Angewandte Chemie37 citations Open access
Semantic Scholar
An In Vitro Model for the Development of Mature Bone Containing an Osteocyte Network
Alexandra Iordachescu, H. Amin, S. Rankin, Richard L. Williams +6 more
201833 citations Open access
Semantic Scholar
Betti reaction enables efficient synthesis of 8-hydroxyquinoline inhibitors of 2-oxoglutarate oxygenases.
C. Thinnes, A. Tumber, C. Yapp, G. Scozzafava +14 more
2015Chemical Communications33 citations Open access
Semantic Scholar
Torin2 exploits replication and checkpoint vulnerabilities to cause death of PI3K-activated triple-negative breast cancer cells
S. Chopra, Anne Jenney, A. Palmer, M. Niepel +9 more
2019Cell Systems29 citations Open access
Semantic Scholar
Inhibition of Haspin kinase promotes cell-intrinsic and extrinsic anti-tumor activity
Johannes C. Melms, S. Vallabhaneni, Caitlin E. Mills, C. Yapp +20 more
2019Cancer Research28 citations Open access
Semantic Scholar
Multiplexed and reproducible high content screening of live and fixed cells using Dye Drop
Caitlin E. Mills, K. Subramanian, M. Hafner, M. Niepel +8 more
2022Nature Communications26 citations Open access
Semantic Scholar
A multi-omic analysis of MCF10A cells provides a resource for integrative assessment of ligand-mediated molecular and phenotypic responses
Sean M. Gross, Mark A. Dane, Rebecca Smith, Kaylyn L. Devlin +46 more
2022Communications Biology24 citations Open access
Semantic Scholar
Superresolution microscopy of the β-carboxysome reveals a homogeneous matrix
M. Niederhuber, Talley J. Lambert, C. Yapp, P. Silver +1 more
2017Molecular Biology of the Cell22 citations Open access
Semantic Scholar
Functional assessment of gap junctions in monolayer and three-dimensional cultures of human tendon cells using fluorescence recovery after photobleaching
M. Kuzma-Kuzniarska, C. Yapp, Thomas W. Pearson-Jones, Andrew K. Jones +1 more
2014Journal of Biomedical Optics20 citations Open access
Semantic Scholar
Ascorbic acid is essential for significant collagen deposition by human tenocytes in vitro
O. Hakimi, R. Poulson, D. Thakkar, C. Yapp +1 more
201420 citations Open access
Semantic Scholar
Highly Multiplexed Fluorescence in Situ Hybridization for in Situ Genomics.
M. Onozato, C. Yapp, Douglas S. Richardson, T. Sundaresan +14 more
2019Journal of Molecular Diagnostics18 citations Open access
Semantic Scholar
Age-dependent regulation of SARS-CoV-2 cell entry genes and cell death programs correlates with COVID-19 disease severity
Z. Inde, C. Yapp, Gaurav N. Joshi, J. Spetz +10 more
2020bioRxiv17 citations Open access
Semantic Scholar
A novel in vitro loading system for high frequency loading of cultured tendon fascicles.
I. Adekanmbi, N. Z. Baboldashti, C. Yapp, S. Franklin +1 more
2013Medical Engineering and Physics9 citations
Semantic Scholar
Author Correction: Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer
A. Färkkilä, D. Gulhan, J. Casado, C. Jacobson +23 more
2020Nature Communications7 citations Open access
Semantic Scholar
Highly multiplexed in situ protein imaging with signal amplification by Immuno-SABER
Sinem K. Saka, Yu Wang, Jocelyn Y. Kishi, Allen Zhu +14 more
2018bioRxiv7 citations Open access
Semantic Scholar
Multi-modal digital pathology for colorectal cancer diagnosis by high-plex immunofluorescence imaging and traditional histology of the same tissue section
Jia-Ren Lin, Yu-An Chen, Daniel Campton, J. Cooper +10 more
2023bioRxiv6 citations Open access
Semantic Scholar

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