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S. F. Brady · SciRah

Researcher profile · Semantic Scholar

S. F. Brady

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S. F. Brady — researcher profile on SciRah

h-index: 22
Works: 50
Citations: 1,725

Most-cited papers

Specific membrane receptors for atrial natriuretic factor in renal and vascular tissues.
M. Napier, Richard L. Vandlen, Georg Albers-Schönberg, R. Nutt +6 more
1984Proceedings of the National Academy of Sciences of the United States of America228 citations Open access
Semantic Scholar
Highly active cyclic and bicyclic somatostatin analogues of reduced ring size
D. Veber, F. W. Holly, R. Nutt, S. J. Bergstrand +4 more
1979Nature193 citations
Semantic Scholar
Amino acid sequence of homologous rat atrial peptides: natriuretic activity of native and synthetic forms.
N. Seidah, Claude Lazure, M. Chrétien, G. Thibault +6 more
1984Proceedings of the National Academy of Sciences of the United States of America188 citations Open access
Semantic Scholar
A super active cyclic hexapeptide analog of somatostatin.
D. F. Veber, R. Saperstein, R. Nutt, Roger M. Freidinger +15 more
1984Life Science130 citations
Semantic Scholar
Practical synthesis of cyclic peptides, with an example of dependence of cyclization yield upon linear sequence
S. F. Brady, S. L. Varga, R. Freidinger, D. Schwenk +3 more
197997 citations
Semantic Scholar
A highly stereoselective synthesis of trans-trisubstituted olefinic bonds
S. F. Brady, M. Ilton, W. S. Johnson
196895 citations
Semantic Scholar
Design and synthesis of a series of potent and orally bioavailable noncovalent thrombin inhibitors that utilize nonbasic groups in the P1 position.
T. Tucker, S. F. Brady, W. C. Lumma, S. Lewis +17 more
1998Journal of Medicinal Chemistry91 citations Open access
Semantic Scholar
Design of novel, potent, noncovalent inhibitors of thrombin with nonbasic P-1 substructures: rapid structure-activity studies by solid-phase synthesis.
W. C. Lumma, K. M. Witherup, T. J. Tucker, S. F. Brady +5 more
1998Journal of Medicinal Chemistry70 citations Open access
Semantic Scholar
Large-scale synthesis of a cyclic hexapeptide analog of somatostatin
S. F. Brady, R. Freidinger, W. J. Paleveda, C. Colton +5 more
198763 citations
Semantic Scholar
Discovery and development of the novel potent orally active thrombin inhibitor N-(9-hydroxy-9-fluorenecarboxy)prolyl trans-4-aminocyclohexylmethyl amide (L-372,460): coapplication of structure-based design and rapid multiple analogue synthesis on solid support.
S. F. Brady, K. J. Stauffer, W. C. Lumma, Graham M. Smith +15 more
1998Journal of Medicinal Chemistry61 citations Open access
Semantic Scholar
Design and synthesis of a pro-drug of vinblastine targeted at treatment of prostate cancer with enhanced efficacy and reduced systemic toxicity.
S. F. Brady, J. Pawluczyk, P. Lumma, D. Feng +9 more
2002Journal of Medicinal Chemistry47 citations
Semantic Scholar
A prostate-specific antigen (PSA)-activated vinblastine prodrug selectively kills PSA-secreting cells in vivo.
D. Defeo-jones, S. F. Brady, D. Feng, Brad Wong +16 more
2002Molecular Cancer Therapeutics46 citations
Semantic Scholar
Approaches to peptidomimetics which serve as surrogates for the cis amide bond: novel disulfide-constrained bicyclic hexapeptide analogs of somatostatic.
S. F. Brady, W. J. Paleveda, B. Arison, R. Saperstein +5 more
199338 citations
Semantic Scholar
Rational design and synthesis of selective BACE-1 inhibitors.
S. F. Brady, S. Singh, Ming-Chih Crouthamel, M. Holloway +7 more
2004Bioorganic & Medicinal Chemistry Letters32 citations Open access
Semantic Scholar
On the low energy solution conformation of somatostatin.
Byron H. Arison, Ralph Hirschmann, William J. Paleveda, S. F. Brady +1 more
1981Biochemical and Biophysical Research Communications - BBRC32 citations
Semantic Scholar
Inhibition of Thrombin by Peptides Containing Lysyl-α-Keto Carbonyl Derivatives
S. Lewis, A. S. Ng, E. A. Lyle, M. Mellott +11 more
1995Thrombosis and Haemostasis30 citations
Semantic Scholar
Amide and α-keto carbonyl inhibitors of thrombin based on arginine and lysine: Synthesis, stability and biological characterization
S. F. Brady, J. Sisko, K. J. Stauffer, C. Colton +7 more
199527 citations
Semantic Scholar
Nonenzymic, biogenetic-like cyclization of a tetraenic acetal to produce the D-homosteroid nucleus
W. S. Johnson, K. Wiedhaup, S. F. Brady, G. L. Olson
197426 citations
Semantic Scholar
Chemical synthesis of rat atrial natriuretic factor by fragment assembly on a solid support
T. Lyle, S. F. Brady, T. Ciccarone, C. Colton +3 more
198725 citations
Semantic Scholar
Recombinant leech antiplatelet protein prevents collagen-mediated platelet aggregation but not collagen graft thrombosis in baboons.
L. Schaffer, John T. Davidson, Peter K. S. Siegl, Robert J. Gould +3 more
1993Arteriosclerosis and Thrombosis A Journal of Vascular Biology24 citations Open access
Semantic Scholar
The Total Synthesis of (±)-Hinesol
J. A. Marshall, S. F. Brady
197024 citations
Semantic Scholar
Some novel, acid-labile amine protecting groups
S. F. Brady, R. Hirschmann, D. Veber
197723 citations
Semantic Scholar
Synthesis and conformational study of a cyclic hexapeptide analog of somatostatin containing dehydrophenylalanine.
S. F. Brady, D. Cochran, R. Nutt, F. W. Holly +6 more
2009International journal of peptide & protein research21 citations
Semantic Scholar
The nonenzymic, biogenetic-like cyclization of a tetraenic acetal
W. S. Johnson, K. Wiedhaup, S. F. Brady, G. L. Olson
196819 citations
Semantic Scholar
The solution conformation Ac‐Pen‐Arg‐Gly‐Asp‐Cys‐OH, a potent fibrinogen receptor antagonist
M. Bogusky, A. M. Naylor, Michael E. Mertzman, S. Pitzenberger +4 more
1993Biopolymers14 citations
Semantic Scholar
Characterization of the Two-step Pathway for Inhibition of Thrombin by α-Ketoamide Transition State Analogs*
S. Lewis, B. J. Lucas, S. F. Brady, J. Sisko +6 more
1998Journal of Biological Chemistry13 citations Open access
Semantic Scholar
The chemistry of spiro(4.5)decane sesquiterpenes.
J. A. Marshall, S. F. Brady, N. Andersen
1974Fortschritte der Chemie organischer Naturstoffe = Progress in the chemistry of organic natural products. Progres dans la chimie des substances organiques naturelles12 citations
Semantic Scholar
The Electronic Absorption Spectra of Carboxylate Derivatives. III. Effects of Solvent and Structure on the Absorption Spectra of α,β-Unsaturated Esters1,2
W. Closson, S. F. Brady, P. J. Orenski
196510 citations
Semantic Scholar
Stereochemical relationships in spirovetivane sesquiterpenes: the total synthesis of hinesol.
J. A. Marshall, S. F. Brady
1969Tetrahedron Letters9 citations
Semantic Scholar
Studies of acetamidomethyl as cysteine protection: Application in synthesis of ANF analogs
S. F. Brady, W. J. Paleveda, R. Nutt
19888 citations
Semantic Scholar
Synthesis and solution conformation of c(D-Trp-D-Cys(SO3-Na+)-Pro-D-Val-Leu), a potent endothelin-A receptor antagonist.
M. Bogusky, S. F. Brady, J. Sisko, R. Nutt +1 more
2009International journal of peptide & protein research6 citations
Semantic Scholar
Development of Novel, Highly Selective Fibrinogen Receptor Antagonists as Potentially Useful Antithrombotic Agents,
R. Nutt, S. F. Brady, C. Colton, J. Sisko +1 more
19926 citations
Semantic Scholar
Structure- and conformation-activity studies leading to potent fibrinogen receptor antagonists containing Arg-Gly-Asp
R. Nutt, S. F. Brady, J. Sisko, T. Ciccarone +6 more
19915 citations
Semantic Scholar
Structure-activity studies of atrial natriuretic factor
R. Nutt, T. Ciccarone, S. F. Brady, C. Colton +6 more
19884 citations
Semantic Scholar
Large-Scale Synthesis of a Cyclic Hexapeptide Analogue of Somatostatin.
S. F. Brady, R. Freidinger, W. J. Paleveda, C. Colton +5 more
19873 citations
Semantic Scholar
Inhibition of thrombin by peptides containing Lysyl-alpha-keto carbonyl derivatives.
S. Lewis, A. S. Ng, E. A. Lyle, M. Mellott +6 more
1995Thrombosis and Haemostasis1 citations
Semantic Scholar
Approaches to Peptidomimetics Which Serve as Surrogates for the cis Amide Bond: Novel Disulfide-Constrained Bicyclic Hexapeptide Analogues of Somatostatin.
S. F. Brady, W. J. Jun. Paleveda, B. Arison, R. Saperstein +5 more
19931 citations
Semantic Scholar
Chemical Synthesis of Rat Atrial Natriuretic Factor by Fragment Assembly on a Solid Support.
T. Lyle, S. F. Brady, T. Ciccarone, C. Colton +3 more
19881 citations
Semantic Scholar
Some novel, acid-labile amine protecting groups 1.
S. F. Brady, R. Hirschmann, D. Veber
1977Journal of Organic Chemistry1 citations
Semantic Scholar
Crystal structure of thrombin in complex with compound 14b
T. Tucker, S. F. Brady, W. C. Lumma, S. Lewis +17 more
20040 citations
Semantic Scholar
Crystal structure of thrombin in complex with compound 1
T. Tucker, S. F. Brady, W. C. Lumma, S. Lewis +17 more
20040 citations
Semantic Scholar
The Solution Conformation of Ac-Pen-Arg-Cly-Asp-Cys-
Michael, J., Bocusky, Adel +9 more
20030 citations
Semantic Scholar
Inhibiteurs de pyridinone thrombine
P. E. Sanderson, Terry A. Lyle, J. Vacca, William C. Lumma +2 more
19970 citations
Semantic Scholar
Amide and alpha-keto carbonyl inhibitors of thrombin based on arginine and lysine: synthesis, stability and biological characterization.
S. F. Brady, J. Sisko, K. J. Stauffer, C. Colton +6 more
1995Bioorganic & Medicinal Chemistry0 citations
Semantic Scholar
Large-Scale Synthesis of L-367,073, a Potent Cyclic Heptapeptide Platelet Fibrinogen Receptor Antagonist,
S. F. Brady, J. Sisko, T. Ciccarone, C. Colton +1 more
19920 citations
Semantic Scholar
Cyclic fibrinogen receptor antagonist
S. F. Brady, R. Nutt, D. Veber
19900 citations
Semantic Scholar
Renin inhibitors containing 2-substituted statine.
D. Veber, M. Bock, S. F. Brady, E. Ulm +6 more
1984Biochemical Society Transactions0 citations
Semantic Scholar
SYNTHESIS AND CONFORMATIONAL STUDY OF A CYCLIC HEXAPEPTIDE ANALOG OF SOMATOSTATIN CONTAINING DEHYDROPHENYLALANINE
S. F. Brady, D. Cochran, R. Nutt, F. W. Holly +6 more
19840 citations
Semantic Scholar
suitable for increasing the feed utilization cyclic hexapeptide
D. Veber, S. F. Brady, S. L. Varga
19770 citations
Semantic Scholar
the same synthetic polypeptide and methods for preparing
D. Veber, S. F. Brady
19730 citations
Semantic Scholar

Frequent co-authors

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R. Nutt×21
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R. Nutt — researcher profile on SciRah
D. Veber×20
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D. Veber — researcher profile on SciRah
J. Sisko×13
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J. Sisko — researcher profile on SciRah
C. Colton×12
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C. Colton — researcher profile on SciRah

×9

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R. Freidinger — researcher profile on SciRah

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S. Lewis — researcher profile on SciRah

K. J. Stauffer×8

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W. J. Paleveda×8

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W. J. Paleveda — researcher profile on SciRah

R. Saperstein×6

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R. Saperstein — researcher profile on SciRah

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E. A. Lyle — researcher profile on SciRah

T. Ciccarone×6

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T. Ciccarone — researcher profile on SciRah

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T. Lyle — researcher profile on SciRah