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K. J. Stauffer · SciRah

Researcher profile · Semantic Scholar

K. J. Stauffer

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K. J. Stauffer — researcher profile on SciRah

h-index: 10
Works: 18
Citations: 411

Most-cited papers

Design and synthesis of a series of potent and orally bioavailable noncovalent thrombin inhibitors that utilize nonbasic groups in the P1 position.
T. Tucker, S. F. Brady, W. C. Lumma, S. Lewis +17 more
1998Journal of Medicinal Chemistry91 citations Open access
Semantic Scholar
Discovery and evaluation of potent P1 aryl heterocycle-based thrombin inhibitors.
M. Young, J. Barrow, K. L. Glass, G. F. Lundell +22 more
2004Journal of Medicinal Chemistry85 citations Open access
Semantic Scholar
Discovery and development of the novel potent orally active thrombin inhibitor N-(9-hydroxy-9-fluorenecarboxy)prolyl trans-4-aminocyclohexylmethyl amide (L-372,460): coapplication of structure-based design and rapid multiple analogue synthesis on solid support.
S. F. Brady, K. J. Stauffer, W. C. Lumma, Graham M. Smith +15 more
1998Journal of Medicinal Chemistry61 citations Open access
Semantic Scholar
9-hydroxyazafluorenes and their use in thrombin inhibitors.
K. J. Stauffer, Peter D. Williams, H. Selnick, P. Nantermet +21 more
2005Journal of Medicinal Chemistry33 citations Open access
Semantic Scholar
Inhibition of Thrombin by Peptides Containing Lysyl-α-Keto Carbonyl Derivatives
S. Lewis, A. S. Ng, E. A. Lyle, M. Mellott +11 more
1995Thrombosis and Haemostasis30 citations
Semantic Scholar
Specific N-methylations of HPV-16 E7 peptides alter binding to the retinoblastoma suppressor protein.
Raymond E. Jones, D. Heimbrook, Hans E. Huber, R. Wegrzyn +5 more
1992Journal of Biological Chemistry30 citations Open access
Semantic Scholar
Amide and α-keto carbonyl inhibitors of thrombin based on arginine and lysine: Synthesis, stability and biological characterization
S. F. Brady, J. Sisko, K. J. Stauffer, C. Colton +7 more
199527 citations
Semantic Scholar
Low molecular weight thrombin inhibitors with excellent potency, metabolic stability, and oral bioavailability.
M. Morrissette, K. J. Stauffer, Peter D. Williams, T. Lyle +13 more
2004Bioorganic & Medicinal Chemistry Letters18 citations Open access
Semantic Scholar
Nonpeptide oxytocin antagonists: analogs of L-371,257 with improved potency.
P. D. Williams, Mark G. Bock, B. E. Evans, Roger M. Freidinger +15 more
1999Bioorganic & Medicinal Chemistry Letters15 citations Open access
Semantic Scholar
Synthesis, structure, and reactivity of (eta/sup 5/-indenyl)tetracarbonylvanadium(I)
R. Kowaleski, D. Kipp, K. J. Stauffer, P. N. Swepston +1 more
198513 citations
Semantic Scholar
Design, synthesis and SAR of a series of 1,3,5-trisubstituted benzenes as thrombin inhibitors.
R. C. A. Isaacs, C. L. Newton, Kellie J. Cutrona, Swati P. Mercer +13 more
2011Bioorganic & Medicinal Chemistry Letters5 citations Open access
Semantic Scholar
Poly‐Bis(Thiocyanato‐N)Bis‐μ‐(1H‐1,2,4‐Triazole‐N2,N4)Metal(II) Complexes with Manganese, Iron, Cobalt, Nickel, Copper and Zinc, and Bis[Tris(Thiocyanato‐N)Tris(μ‐4H‐1,2,4‐Triazole‐N1)Nickel(II)‐N2,N2′,N2″]Nickel(II)
J. Haasnoot, D. W. Engelfriet, J. Reedijk, J. Cronin +4 more
20072 citations
Semantic Scholar
Inhibition of thrombin by peptides containing Lysyl-alpha-keto carbonyl derivatives.
S. Lewis, A. S. Ng, E. A. Lyle, M. Mellott +6 more
1995Thrombosis and Haemostasis1 citations
Semantic Scholar
Thrombin in complex with an azafluorenyl inhibitor 23b
K. J. Stauffer, Peter D. Williams, H. Selnick, P. Nantermet +21 more
20050 citations
Semantic Scholar
Crystal structure of thrombin in complex with compound 14b
T. Tucker, S. F. Brady, W. C. Lumma, S. Lewis +17 more
20040 citations
Semantic Scholar
crystal structue of Thrombin in complex with a potent P1 heterocycle-Aryl based inhibitor
M. Young, J. Barrow, K. L. Glass, G. F. Lundell +17 more
20040 citations
Semantic Scholar
Crystal structure of thrombin in complex with compound 1
T. Tucker, S. F. Brady, W. C. Lumma, S. Lewis +17 more
20040 citations
Semantic Scholar
Amide and alpha-keto carbonyl inhibitors of thrombin based on arginine and lysine: synthesis, stability and biological characterization.
S. F. Brady, J. Sisko, K. J. Stauffer, C. Colton +6 more
1995Bioorganic & Medicinal Chemistry0 citations
Semantic Scholar

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S. Lewis×11
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J. Cook×10
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E. A. Lyle×10
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