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G. L. Olson · SciRah

Researcher profile · Semantic Scholar

G. L. Olson

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G. L. Olson — researcher profile on SciRah

h-index: 19
Works: 56
Citations: 1,215

Most-cited papers

Discovery and clinical introduction of first-in-class imipridone ONC201
J. Allen, C. L. Kline, V. Prabhu, Jessica Wagner +28 more
2016OncoTarget147 citations Open access
Semantic Scholar
Designing isoform-specific peptide disruptors of protein kinase A localization
L. L. Burns-Hamuro, Yuliang Ma, S. Kammerer, U. Reineke +6 more
2003Proceedings of the National Academy of Sciences of the United States of America138 citations Open access
Semantic Scholar
Design and synthesis of a protein. beta. -turn mimetic
G. L. Olson, M. Voss, D. Hill, M. Kahn +2 more
199080 citations
Semantic Scholar
A dopamine receptor model and its application in the design of a new class of rigid pyrrolo[2,3-g]isoquinoline antipsychotics.
G. L. Olson, Hoh Cheung, K. Morgan, John F. Blount +4 more
1981Journal of Medicinal Chemistry75 citations
Semantic Scholar
Preclinical evaluation of the imipridone family, analogs of clinical stage anti-cancer small molecule ONC201, reveals potent anti-cancer effects of ONC212
Jessica Wagner, C. L. Kline, M. Ralff, Avital Lev +10 more
2017Cell Cycle70 citations Open access
Semantic Scholar
Conformational analysis of dipeptide mimetics
P. Gillespie, J. Cicariello, G. L. Olson
199765 citations
Semantic Scholar
Vitamin a synthesis by sulfone alkyaltion-elimination. C15 halide, C5 hydroxy sulfone approach.
G. L. Olson, Ho-Chuen Cheung, K. Morgan, Christian Neukom +1 more
1976Journal of Organic Chemistry65 citations
Semantic Scholar
Peptidomimetic compounds that inhibit antigen presentation by autoimmune disease-associated class II major histocompatibility molecules
F. Falcioni, Kouichi Ito, D. Vidović, C. Belunis +13 more
1999Nature Biotechnology57 citations
Semantic Scholar
Peptide mimetics of thyrotropin-releasing hormone based on a cyclohexane framework: design, synthesis, and cognition-enhancing properties.
G. L. Olson, Hoh Cheung, E. Chiang, V. Madison +4 more
1995Journal of Medicinal Chemistry54 citations
Semantic Scholar
Disruption of Protein Kinase A Localization Using a Trans-activator of Transcription (TAT)-conjugated A-kinase-anchoring Peptide Reduces Cardiac Function*
Hemal H. Patel, Lora Hamuro, Byeongjo Chun, Y. Kawaraguchi +11 more
2010Journal of Biological Chemistry47 citations Open access
Semantic Scholar
The angular structure of ONC201, a TRAIL pathway-inducing compound, determines its potent anti-cancer activity
Jessica Wagner, C. L. Kline, R. Pottorf, B. R. Nallaganchu +4 more
2014OncoTarget42 citations Open access
Semantic Scholar
A stereospecific synthesis of vitamin A from 2,2,6-trimethyl-cyclohexanone.
G. L. Olson, H. Cheung, K. Morgan, R. Borer +1 more
1976Helvetica Chimica Acta33 citations
Semantic Scholar
Design and Synthesis of a Competent Pyrrolinone−Peptide Hybrid Ligand for the Class II Major Histocompatibility Complex Protein HLA-DR1
Amos B. Smith, Andrew B. Benowitz, P. Sprengeler, J. Barbosa +8 more
199932 citations
Semantic Scholar
Small molecule inhibitor of antigen binding and presentation by HLA-DR2b as a therapeutic strategy for the treatment of multiple sclerosis
Nian-Nian Ji, Animesh Somanaboeina, Aakanksha Dixit, K. Kawamura +4 more
2013Journal of Immunology30 citations Open access
Semantic Scholar
Monocyclic and tricyclic analogs of quinolones: mechanism of action
N. Georgopapadakou, B. A. Dix, P. Angehrn, A. Wick +1 more
1987Antimicrobial Agents and Chemotherapy29 citations Open access
Semantic Scholar
Letter: Allenic retinals and visual pigment analogues.
K. Nakanishi, A. Yudd, Rosalie K. Crouch, G. L. Olson +4 more
1976Journal of the American Chemical Society28 citations
Semantic Scholar
Nonenzymic, biogenetic-like cyclization of a tetraenic acetal to produce the D-homosteroid nucleus
W. S. Johnson, K. Wiedhaup, S. F. Brady, G. L. Olson
197426 citations
Semantic Scholar
Synthesis of 1,2,5‐Thiadiazolidin‐3‐one 1,1‐Dioxide Derivatives and Evaluation of Their Affinity for MHC Class‐II Proteins
L. Ducry, Stefan Reinelt, P. Seiler, F. Diederich +3 more
199920 citations
Semantic Scholar
Structure activity of C-terminal modified analogs of Ac-CCK-7.
J. Tilley, W. Danho, Shian-Jan Shiuey, Irina Kulesha +12 more
2009International journal of peptide & protein research19 citations
Semantic Scholar
The nonenzymic, biogenetic-like cyclization of a tetraenic acetal
W. S. Johnson, K. Wiedhaup, S. F. Brady, G. L. Olson
196819 citations
Semantic Scholar
DESIGN, SYNTHESIS, AND EVALUATION OF A PYRROLINONE-PEPTIDE HYBRID LIGAND FOR THE CLASS II MHC PROTEIN HLA-DR1
Amos B. Smith, Andrew B. Benowitz, M. Guzmán, P. Sprengeler +7 more
199818 citations
Semantic Scholar
Design, synthesis, and three-dimensional structural characterization of a constrained Ω-loop excised from interleukin-1α
R. Sarabu, Kathleen Lovey, V. Madison, D. Fry +3 more
199314 citations
Semantic Scholar
Neuropathology and amphetamine-induced turning resulting from AF64A injections into the striatum of the rat.
S. A. Stwertka, G. L. Olson
1986Life Science14 citations
Semantic Scholar
A New Vanadium (V)-Catalyzed Rearrangement of 17α-Ethynyl-17β-hydroxy Steroids to 17(20)-En-21-al Compounds - Key Intermediates in the Synthesis of the Corticosteroid Side Chain.
G. L. Olson, K. Morgan, G. Saucy
197614 citations
Semantic Scholar
Inhibition of amyloid β‐peptide production by blockage of β‐secretase cleavage site of amyloid precursor protein
Chan Hyun Na, S. Jeon, Guangtao Zhang, G. L. Olson +1 more
200713 citations
Semantic Scholar
The Crystal Structure of a Pyrrolinone−Peptide Hybrid Ligand Bound to the Human Class II MHC Protein HLA-DR1
Kon-Ho Lee, G. L. Olson, D. Bolin, Andrew B. Benowitz +4 more
200011 citations
Semantic Scholar
Syntheses of an antipsychotic pyrrolo[2,3-g]isoquinoline from areca alkaloids
D. L. Coffen, U. Hengartner, D. A. Katonak, Mary E. Mulligan +3 more
198411 citations
Semantic Scholar
A new synthesis of .alpha.-tocopherol
G. L. Olson, Ho-Chuen Cheung, K. Morgan, G. Saucy
198010 citations
Semantic Scholar
HLA-DR15-specific inhibition attenuates autoreactivity to the Goodpasture antigen.
M. Huynh, P. Eggenhuizen, G. L. Olson, N. B. Rao +5 more
2019Journal of Autoimmunity8 citations
Semantic Scholar
Detonation associated with oxidations of tetrahydropyranyl ether derivatives. A serious note of caution
A. Meyers, S. Schwartzman, G. L. Olson, Ho-Chuen Cheung
19768 citations
Semantic Scholar
Conformationally Defined Pyrroloisoquinoline Antipsychotics: Implications for the Mode of Interaction of Antipsychotic Drugs with the Dopamine Receptor
G. L. Olson, H. Cheung, E. Chiang, L. Berger
19835 citations
Semantic Scholar
Synthesis and reactions of cobalt complexes: A laboratory experiment
G. L. Olson
19694 citations
Semantic Scholar
Correction: Discovery and clinical introduction of first-in-class imipridone ONC201
J. Allen, C. L. Kline, V. Prabhu, Jessica Wagner +28 more
2021OncoTarget2 citations Open access
Semantic Scholar
Oxazole- and imidazole-based Ser-Leu dipeptide mimetics in potent inhibitors of antigen presentation by MHC class II DR molecules.
R. Sarabu, D. Bolin, R. Campbell, J. R. Cooper +5 more
2002Drug Design and Discovery2 citations
Semantic Scholar
Allenic retinals and visual pigment analogues
K. Nakanishi, A. Yudd, R. Crouch, G. L. Olson +4 more
19762 citations
Semantic Scholar
Inhibition of amyloid beta-peptide production by blockage of beta-secretase cleavage site of amyloid precursor protein.
Chan Hyun Na, S. Jeon, Guangtao Zhang, G. L. Olson +1 more
2007Journal of Neurochemistry1 citations
Semantic Scholar
Synthesis of 1,2,5-Thiadiazolidin-3-one 1,1-Dioxide Derivatives and Evaluation of Their Affinity for MHC Class-II Proteins.
L. Ducry, Stefan Reinelt, P. Seiler, F. Diederich +3 more
20001 citations
Semantic Scholar
An ‘Umpolung’ Route to Peptide Mimetics of Thyrotropin-Releasing Hormone based on a cyclohexane framework†
M. Bös, G. L. Olson, G. Vincent
19941 citations
Semantic Scholar
A NEW SYNTHESIS OF α-TOCOPHEROL
G. L. Olson, H. Cheung, K. Morgan, G. Saucy
19801 citations
Semantic Scholar
Abstract 3245: Preclinical evaluation of the imipridone family of small molecules, including analogues of clinical-stage anti-cancer small molecule ONC201, reveals potent anti-cancer effects of ONC212
Jessica Wagner, C. L. Kline, G. L. Olson, B. R. Nallaganchu +5 more
20170 citations
Semantic Scholar
PROCESS FOR THE PREPARATION OF ESTERS OF 5-FORMYL-3-METHYL-2 , 4-PENTADIEN-1-OL 75 ) Inventor :
G. L. Olson, Bernard S. Leon, G. Johnston
20170 citations
Semantic Scholar
Structure-activity relationships (SAR) and mechanistic analysis of clinical-stage anti-cancer small molecule ONC201 analogues.
Jessica Wagner, G. L. Olson, B. R. Nallaganchu, R. Pottorf +9 more
20160 citations
Semantic Scholar
Abstract 4826: ONC212 exhibits increased cytotoxicity relative to ONC201 in a subset of human pancreatic cancer cell lines
Avital Lev, Jessica Wagner, D. Dicker, M. Stogniew +5 more
20160 citations
Semantic Scholar
Abstract 349: Structure-activity relationships and mechanistic analysis of analogues of the clinical-stage anti-cancer small molecule ONC201
Jessica Wagner, G. L. Olson, Nallaganchu Rao Bhaskara, R. Pottorf +8 more
20160 citations
Semantic Scholar
Abstract 4499: Cytotoxicity, biochemical activity, and structural analysis of ONC201 and comparisons to a biologically inactive isomer
Jessica Wagner, C. L. Kline, R. Pottorf, B. R. Nallaganchu +4 more
20150 citations
Semantic Scholar
Multiple Sclerosis Therapeutic Strategy for the Treatment of and Presentation by HLA-DR2b as a Small Molecule Inhibitor of Antigen Binding
Nian-Nian Ji, Animesh Somanaboeina, Aakanksha Dixit, K. Kawamura +4 more
20130 citations
Semantic Scholar
An “Umpolung” Route to Peptide Mimetics of Thyrotropin-Releasing Hormone Based on a Cyclohexane Framework.
M. Boes, G. L. Olson, G. Vincent
20100 citations
Semantic Scholar
Peptide Mimetics of Thyrotropin‐Releasing Hormone Based on a Cyclohexane Framework: Design, Synthesis, and Cognition‐Enhancing Properties.
G. L. Olson, H. Cheung, E. Chiang, V. Madison +4 more
20100 citations
Semantic Scholar
Beta-amyloid peptide aggregation regulating peptide with d-amino acids
M. Findeis, G. L. Olson, K. Phillips, C. Self
20000 citations
Semantic Scholar
Bioorganic Chemistry: Peptides and Proteins Edited by Sidney M. Hecht. Oxford University Press, New York. 1998. x + 532 pp. 17 × 24.5 cm. ISBN 0-19-508468-3. $75.00.
J. Freundlich, G. L. Olson
19990 citations
Semantic Scholar

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