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Emma M. Carrington · SciRah

Researcher profile · Semantic Scholar

Emma M. Carrington

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Emma M. Carrington — researcher profile on SciRah

h-index: 21
Works: 38
Citations: 1,710

Most-cited papers

Adoptive cellular therapy with T cells expressing the dendritic cell growth factor Flt3L drives epitope spreading and antitumor immunity
Junyun Lai, Sherly Mardiana, Imran G. House, K. Sek +16 more
2020Nature Immunology196 citations
Semantic Scholar
Anti-apoptotic proteins BCL-2, MCL-1 and A1 summate collectively to maintain survival of immune cell populations both in vitro and in vivo
Emma M. Carrington, Y. Zhan, J. Brady, Jian-Guo Zhang +14 more
2017Cell Death and Differentiation149 citations Open access
Semantic Scholar
Selected TLR ligands and viruses promote helper-independent CTL priming by upregulating CD40L (CD154) on dendritic cells
Susan B. Johnson, Y. Zhan, R. Sutherland, A. Mount +7 more
2009Immunity114 citations Open access
Semantic Scholar
GM‐CSF increases cross‐presentation and CD103 expression by mouse CD8+ spleen dendritic cells
Y. Zhan, Emma M. Carrington, A. V. van Nieuwenhuijze, S. Bedoui +7 more
2011European Journal of Immunology109 citations Open access
Semantic Scholar
BH3 mimetics antagonizing restricted prosurvival Bcl-2 proteins represent another class of selective immune modulatory drugs
Emma M. Carrington, I. Vikstrom, A. Light, R. Sutherland +5 more
2010Proceedings of the National Academy of Sciences of the United States of America104 citations Open access
Semantic Scholar
Proapoptotic BH3-Only Protein Bid Is Essential For Death Receptor–Induced Apoptosis of Pancreatic β-Cells
M. McKenzie, Emma M. Carrington, T. Kaufmann, A. Strasser +4 more
2008Diabetes97 citations Open access
Semantic Scholar
Life and Death of Activated T Cells: How Are They Different from Naïve T Cells?
Y. Zhan, Emma M. Carrington, Yu-Xia Zhang, S. Heinzel +1 more
2017Frontiers in Immunology93 citations Open access
Semantic Scholar
Characterisation of mice lacking all functional isoforms of the pro-survival BCL-2 family member A1 reveals minor defects in the haematopoietic compartment
Robyn L. Schenk, Selma Tuzlak, Emma M. Carrington, Y. Zhan +8 more
2017Cell Death and Differentiation72 citations Open access
Semantic Scholar
Mutually exclusive regulation of T cell survival by IL-7R and antigen receptor-induced signals
Paul Koenen, S. Heinzel, Emma M. Carrington, L. Happo +7 more
2013Nature Communications69 citations Open access
Semantic Scholar
MCL-1 is required throughout B-cell development and its loss sensitizes specific B-cell subsets to inhibition of BCL-2 or BCL-XL
I. Vikström, A. Slomp, Emma M. Carrington, Laura M. Moesbergen +10 more
2016Cell Death and Disease54 citations Open access
Semantic Scholar
Prosurvival Bcl-2 family members reveal a distinct apoptotic identity between conventional and plasmacytoid dendritic cells
Emma M. Carrington, Jian-Guo Zhang, R. Sutherland, I. Vikstrom +16 more
2015Proceedings of the National Academy of Sciences of the United States of America54 citations Open access
Semantic Scholar
Resident and Monocyte-Derived Dendritic Cells Become Dominant IL-12 Producers under Different Conditions and Signaling Pathways
Y. Zhan, Yuekang Xu, Shirley G. K. Seah, J. Brady +6 more
2010Journal of Immunology52 citations Open access
Semantic Scholar
Bcl‐2 Antagonists Kill Plasmacytoid Dendritic Cells From Lupus‐Prone Mice and Dampen Interferon‐α Production
Y. Zhan, Emma M. Carrington, Hyun-Ja Ko, I. Vikstrom +11 more
2015Arthritis & Rheumatology51 citations
Semantic Scholar
The inflammatory cytokine, GM‐CSF, alters the developmental outcome of murine dendritic cells
Y. Zhan, J. Vega-Ramos, Emma M. Carrington, J. Villadangos +2 more
2012European Journal of Immunology49 citations Open access
Semantic Scholar
Islet β-Cells Deficient in Bcl-xL Develop but Are Abnormally Sensitive to Apoptotic Stimuli
Emma M. Carrington, M. McKenzie, Elisa S. Jansen, M. Myers +6 more
2009Diabetes49 citations Open access
Semantic Scholar
Rotavirus Infection of Infant and Young Adult Nonobese Diabetic Mice Involves Extraintestinal Spread and Delays Diabetes Onset
K. Graham, J. O'Donnell, Yan Tan, N. Sanders +3 more
2007Journal of Virology48 citations Open access
Semantic Scholar
TNF Receptor 1 Deficiency Increases Regulatory T Cell Function in Nonobese Diabetic Mice
Jonathan Chee, Eveline Angstetra, L. Mariana, K. Graham +7 more
2011Journal of Immunology44 citations Open access
Semantic Scholar
The life and death of immune cell types: the role of BCL‐2 anti‐apoptotic molecules
Emma M. Carrington, D. Tarlinton, D. Gray, N. Huntington +2 more
2017Immunology and Cell Biology43 citations Open access
Semantic Scholar
GM-CSF Quantity Has a Selective Effect on Granulocytic vs. Monocytic Myeloid Development and Function
Li Sun, J. Rautela, Rebecca B Delconte, F. Souza-Fonseca-Guimaraes +7 more
2018Frontiers in Immunology42 citations Open access
Semantic Scholar
Defects in the ‘Bcl-2-regulated’ apoptotic pathway leads to preferential increase of CD25lowFoxP3+ anergic CD4+ T cells
Y. Zhan, Yuxia Zhang, D. Gray, Emma M. Carrington +6 more
2011Journal of Immunology38 citations Open access
Semantic Scholar
The Closely Related CD103+ Dendritic Cells (DCs) and Lymphoid-Resident CD8+ DCs Differ in Their Inflammatory Functions
Z. Jiao, S. Bedoui, J. Brady, A. Walter +9 more
2014PLoS ONE33 citations Open access
Semantic Scholar
Role of regulatory T cells in xenotransplantation
P. O'Connell, S. Yi, Emma M. Carrington, A. Lew
2010Current Opinion in Organ Transplantation19 citations
Semantic Scholar
In Situ Protection Against Islet Allograft Rejection by CTLA4Ig Transduction
Sarah L. Londrigan, R. Sutherland, J. Brady, Emma M. Carrington +5 more
2010Transplantation18 citations Open access
Semantic Scholar
Unlike CD4+ T‐cell help, CD28 costimulation is necessary for effective primary CD8+ T‐cell influenza‐specific immunity
Shirley G. K. Seah, Emma M. Carrington, W. Ng, G. Belz +8 more
2012European Journal of Immunology16 citations Open access
Semantic Scholar
Recipient BCL2 inhibition and NK cell ablation form part of a reduced intensity conditioning regime that improves allo-bone marrow transplantation outcomes
Yu-hao Jiao, Joanne E. Davis, J. Rautela, Emma M. Carrington +11 more
2018Cell Death and Differentiation15 citations Open access
Semantic Scholar
BCL-XL antagonism selectively reduces neutrophil life span within inflamed tissues without causing neutropenia.
Emma M. Carrington, Cynthia Louis, T. Kratina, Manuela S. Hancock +22 more
2021Blood Advances13 citations Open access
Semantic Scholar
Reducing or increasing β‐cell apoptosis without inflammation does not affect diabetes initiation in neonatal NOD mice
Emma M. Carrington, Cameron Kos, Y. Zhan, B. Krishnamurthy +1 more
2011European Journal of Immunology13 citations
Semantic Scholar
Influenza‐induced, helper‐independent CD8+ T cell responses use CD40 costimulation at the late phase of the primary response
Shirley G. K. Seah, J. Brady, Emma M. Carrington, W. Ng +7 more
2013Journal of Leukocyte Biology12 citations
Semantic Scholar
DNA-binding of the Tet-transactivator curtails antigen-induced lymphocyte activation in mice
E. Ottina, V. Peperzak, K. Schoeler, Emma M. Carrington +6 more
2017Nature Communications9 citations Open access
Semantic Scholar
Selective Depletion of Cross-Presenting Dendritic Cells Enhances Islet Allograft Survival
R. Sutherland, Y. Zhan, Emma M. Carrington, Sarah L. Londrigan +1 more
2011Cell Transplantation9 citations Open access
Semantic Scholar
Cognate antigen engagement on parenchymal cells stimulates CD8+ T cell proliferation in situ
R. Sutherland, Sarah L. Londrigan, J. Brady, Emma M. Carrington +7 more
2017Nature Communications8 citations Open access
Semantic Scholar
Monocyte-Derived Dendritic Cells Impair Early Graft Function following Allogeneic Islet Transplantation
K. Chow, Emma M. Carrington, Y. Zhan, A. Lew +1 more
2017Cell Transplantation7 citations Open access
Semantic Scholar
Shutdown of immunological priming and presentation after in vivo administration of adenovirus
RM Sutherland, SL Londrigan, JL Brady, H. Azher +5 more
2011Gene Therapy5 citations Open access
Semantic Scholar
The linear range for accurately quantifying antigen‐specific T‐cell frequencies by tetramer staining during natural immune responses
Shirley G. K. Seah, R. Sutherland, N. L. La Gruta, L. Brown +6 more
2011European Journal of Immunology5 citations
Semantic Scholar
Characterisation of mice lacking all functional isoforms of the pro-survival BCL-2 family member A1 reveals minor defects in the haematopoietic compartment
Robyn L. Schenk, Selma Tuzlak, Emma M. Carrington, Y. Zhan +8 more
2017Cell Death and Differentiation1 citations Open access
Semantic Scholar
Diabetic mice Regulatory T Cell Function in Nonobese TNF Receptor 1 Deficiency Increases
B. Krishnamurthy, H. Thomas, Santamaría, J. Allison +7 more
20110 citations
Semantic Scholar
GENERATING EFFECTIVE LOCAL IMMUNOSUPPRESSION: PROTECTION OF ISLET ALLOGRAFTS WITHOUT COMPROMISING SYSTEMIC IMMUNITY: 465
Sarah L. Londrigan, R. Sutherland, J. Brady, Y. Zhan +2 more
20080 citations Open access
Semantic Scholar
IN VIVO SUPPRESSION OF THE CD8 T CELL RESPONSE BY SELECTIVE DEPLETION OF CROSS-PRESENTING DENDRITIC CELLS: 1918
R. Sutherland, Y. Zhan, Ming-Lee Lin, Emma M. Carrington +2 more
20080 citations
Semantic Scholar

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