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Junyun Lai · SciRah

Researcher profile · Semantic Scholar

Junyun Lai

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Junyun Lai — researcher profile on SciRah

h-index: 16
Works: 30
Citations: 2,154

Most-cited papers

Macrophage-Derived CXCL9 and CXCL10 Are Required for Antitumor Immune Responses Following Immune Checkpoint Blockade
Imran G. House, P. Savas, Junyun Lai, Amanda X. Y. Chen +16 more
2019Clinical Cancer Research619 citations Open access
Semantic Scholar
Cellular networks controlling T cell persistence in adoptive cell therapy
Jack D. Chan, Junyun Lai, C. Slaney, A. Kallies +2 more
2021Nature reviews. Immunology225 citations
Semantic Scholar
FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy
Jack D. Chan, C. Scheffler, Isabelle Munoz, K. Sek +34 more
2024Nature217 citations Open access
Semantic Scholar
CRISPR/Cas9 mediated deletion of the adenosine A2A receptor enhances CAR T cell efficacy
Lauren Giuffrida, K. Sek, M. Henderson, Junyun Lai +15 more
2021Nature Communications207 citations Open access
Semantic Scholar
Adoptive cellular therapy with T cells expressing the dendritic cell growth factor Flt3L drives epitope spreading and antitumor immunity
Junyun Lai, Sherly Mardiana, Imran G. House, K. Sek +16 more
2020Nature Immunology196 citations
Semantic Scholar
IL-15 Preconditioning Augments CAR T Cell Responses to Checkpoint Blockade for Improved Treatment of Solid Tumors.
Lauren Giuffrida, K. Sek, M. Henderson, Imran G. House +16 more
2020Molecular Therapy99 citations Open access
Semantic Scholar
MAIT cells regulate NK cell-mediated tumor immunity
Emma V. Petley, Hui-Fern Koay, M. Henderson, K. Sek +27 more
2021Nature Communications90 citations Open access
Semantic Scholar
Rewiring endogenous genes in CAR T cells for tumour-restricted payload delivery
Amanda X. Y. Chen, K. M. Yap, Joelle S. Kim, K. Sek +30 more
2025Nature77 citations Open access
Semantic Scholar
Single-cell protein expression profiling resolves circulating and resident memory T cell diversity across tissues and infection contexts.
Maximilien Evrard, E. Becht, R. Fonseca, Andreas Obers +16 more
2023Immunity71 citations Open access
Semantic Scholar
The NLRP3 inflammasome affects DNA damage responses after oxidative and genotoxic stress in dendritic cells
G. Licandro, Hwei Ling Khor, O. Beretta, Junyun Lai +7 more
2013European Journal of Immunology69 citations
Semantic Scholar
Dual PD-1 and CTLA-4 Checkpoint Blockade Promotes Antitumor Immune Responses through CD4+Foxp3− Cell–Mediated Modulation of CD103+ Dendritic Cells
P. Beavis, M. Henderson, Lauren Giuffrida, A. Davenport +13 more
2018Cancer immunology research64 citations Open access
Semantic Scholar
Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses
K. Chan, Juliana Gomez, Chelisa Cardinez, Kumari Nishi +22 more
2022Cancer Cell44 citations Open access
Semantic Scholar
CD28-CAR-T cell activation through FYN kinase signaling rather than LCK enhances therapeutic performance
Ling Wu, J. Brzostek, Previtha Dawn Sakthi Vale, Qianru Wei +12 more
2023Cell Reports Medicine36 citations Open access
Semantic Scholar
Defining the expression hierarchy of latent T-cell epitopes in Epstein-Barr virus infection with TCR-like antibodies
A. C. Sim, Chien Tei Too, M. Oo, Junyun Lai +11 more
2013Scientific Reports24 citations Open access
Semantic Scholar
Targeting CAR to the Peptide-MHC Complex Reveals Distinct Signaling Compared to That of TCR in a Jurkat T Cell Model
Ling-Tao Wu, J. Brzostek, Shvetha Sankaran, Qianru Wei +5 more
2021Cancers22 citations Open access
Semantic Scholar
Targeting Epstein-Barr virus-transformed B lymphoblastoid cells using antibodies with T-cell receptor-like specificities.
Junyun Lai, W. Tan, Chien Tei Too, J. A. L. Choo +10 more
2016Blood22 citations Open access
Semantic Scholar
Tumor site-directed A1R expression enhances CAR T cell function and improves efficacy against solid tumors
K. Sek, Amanda X. Y. Chen, Thomas J Cole, Jesse D. Armitage +32 more
2025Nature Communications14 citations Open access
Semantic Scholar
CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity.
Imran G. House, Emily B. Derrick, K. Sek, Amanda X. Y. Chen +25 more
2023Cell Reports13 citations Open access
Semantic Scholar
Switching on the green light for chimeric antigen receptor T‐cell therapy
Sherly Mardiana, Junyun Lai, Imran G. House, P. Beavis +1 more
2019Clinical & Translational Immunology13 citations Open access
Semantic Scholar
TCR–like antibodies mediate complement and antibody-dependent cellular cytotoxicity against Epstein-Barr virus–transformed B lymphoblastoid cells expressing different HLA-A*02 microvariants
Junyun Lai, J. A. L. Choo, W. Tan, Chien Tei Too +11 more
2017Scientific Reports13 citations Open access
Semantic Scholar
Flt3L-mediated tumor cDC1 expansion enhances immunotherapy by priming stem-like CD8+ T cells in lymph nodes
Junyun Lai, Cheok Weng Chan, Jesse D. Armitage, Katherine M. Audsley +26 more
2026Nature Immunology9 citations Open access
Semantic Scholar
A2AR eGFP reporter mouse enables elucidation of A2AR expression dynamics during anti-tumor immune responses
Kirsten L. Todd, Junyun Lai, K. Sek, Yu-Kuan Huang +23 more
2023Nature Communications9 citations Open access
Semantic Scholar
Augmenting Adoptive T-cell Immunotherapy by Targeting the PD-1/PD-L1 Axis
Junyun Lai, P. Beavis, Jasmine Li, P. Darcy
2021Cancer Research5 citations Open access
Semantic Scholar
CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity.
Imran G. House, Emily B. Derrick, K. Sek, Amanda X. Y. Chen +25 more
2024Cell Reports4 citations Open access
Semantic Scholar
Characterization and Establishment of a Novel EBV Strain Simultaneously Associated With Nasopharyngeal Carcinoma and B-Cell Lymphoma
Feng-Gang Yu, N. Syn, Yanan Lu, Q. Chong +6 more
2020bioRxiv4 citations Open access
Semantic Scholar
Implantable drug delivery system improves tolerability of anti-CD40/anti-PD1 and chemotherapy in a murine model of breast cancer.
Samantha J. Wade, E. Minaei, Ashleigh Hope, Ross J Turner +10 more
2025European Journal of Pharmaceutical Sciences3 citations Open access
Semantic Scholar
Utilizing distinct CAR and TCR signaling to generate enhanced cellular immunotherapy
N. Gascoigne, Ling Wu, J. Brzostek, Qianru Wei +7 more
2022Journal of Immunology0 citations
Semantic Scholar
MAIT cells regulate NK cell mediated tumor immunity
Emma V. Petley, Hui-Fern Koay, M. Henderson, K. Sek +25 more
20200 citations Open access
Semantic Scholar
Abstract 1425: Chimeric antigen receptors based on T cell receptor-like antibodies
Ling-Tao Wu, J. Brzostek, Shvetha Sankaran, T. Tan +5 more
2019Clinical research0 citations
Semantic Scholar
Abstract B095: Targeting Epstein-Barr virus transformed B lymphoblastoid cells using antibodies with T cell receptor-like specificities
Junyun Lai, W. Tan, Chien Tei Too, N. Srinivasan +5 more
20160 citations
Semantic Scholar

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P. Beavis×20
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P. Beavis — researcher profile on SciRah
Imran G. House×17
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Imran G. House — researcher profile on SciRah
P. Darcy×16
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K. Sek×14
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K. Sek — researcher profile on SciRah

Amanda X. Y. Chen

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Amanda X. Y. Chen — researcher profile on SciRah

Kirsten L. Todd×13

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Kirsten L. Todd — researcher profile on SciRah

Emma V. Petley×12

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Emma V. Petley — researcher profile on SciRah

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M. Henderson×8

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M. Henderson — researcher profile on SciRah

Lauren Giuffrida×8

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Lauren Giuffrida — researcher profile on SciRah

Jack D. Chan×8

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Jack D. Chan — researcher profile on SciRah

Sherly Mardiana×7

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Sherly Mardiana — researcher profile on SciRah