Researcher profile · Semantic Scholar

L. Happo

h-index: 11
Works: 15
Citations: 783

Most-cited papers

Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis
EM Michalak, ES Jansen, L. Happo, M. Cragg +5 more
2009Cell Death and Differentiation166 citations Open access
Semantic Scholar
BH3-only proteins in apoptosis at a glance
L. Happo, A. Strasser, S. Cory
2012Journal of Cell Science164 citations Open access
Semantic Scholar
Maximal killing of lymphoma cells by DNA damage-inducing therapy requires not only the p53 targets Puma and Noxa, but also Bim.
L. Happo, M. Cragg, B. Phipson, Jon M Haga +9 more
2010Blood109 citations Open access
Semantic Scholar
Prevalence and severity of dysmenorrhoea, and management options reported by young Australian women.
A. Subasinghe, L. Happo, Y. Jayasinghe, S. Garland +2 more
2016Australian Family Physician86 citations
Semantic Scholar
Mutually exclusive regulation of T cell survival by IL-7R and antigen receptor-induced signals
Paul Koenen, S. Heinzel, Emma M. Carrington, L. Happo +7 more
2013Nature Communications69 citations Open access
Semantic Scholar
Translation inhibitors induce cell death by multiple mechanisms and Mcl-1 reduction is only a minor contributor
L. Lindqvist, I. Vikström, J. Chambers, K. McArthur +12 more
2012Cell Death and Disease56 citations Open access
Semantic Scholar
Caloric restriction modulates Mcl-1 expression and sensitizes lymphomas to BH3 mimetic in mice.
O. Meynet, B. Zunino, L. Happo, Ludivine A. Pradelli +13 more
2013Blood51 citations
Semantic Scholar
Therapeutic Response to Non-genotoxic Activation of p53 by Nutlin3a Is Driven by PUMA-Mediated Apoptosis in Lymphoma Cells.
L. J. Valente, B. Aubrey, M. Herold, Gemma L. Kelly +7 more
2016Cell Reports37 citations Open access
Semantic Scholar
Transforming Growth Factor- (cid:1) Directly Induces p53-up-regulated Modulator of Apoptosis (PUMA) during the Rapid Induction of Apoptosis in Myc-driven B-cell Lymphomas *
L. Spender, M. Carter, Darren I. O'Brien, L. Clark +5 more
201328 citations
Semantic Scholar
Pharmacological blockade of Bcl-2, Bcl-xL and Bcl-w by the BH3 mimetic ABT-737 has only minor impact on tumour development in p53-deficient mice
S. Grabow, P. Waring, L. Happo, M. Cook +3 more
2011Cell Death and Differentiation17 citations Open access
Semantic Scholar
BCR-signaling-induced cell death demonstrates dependency on multiple BH3-only proteins in a murine model of B-cell lymphoma
M. Carter, K. Cox, S. Blakemore, Yury Bogdanov +5 more
2015Cell Death and Differentiation11 citations Open access
Semantic Scholar
Neither loss of Bik alone, nor combined loss of Bik and Noxa, accelerate murine lymphoma development or render lymphoma cells resistant to DNA damaging drugs
L. Happo, B. Phipson, G. Smyth, A. Strasser +1 more
2012Cell Death and Disease11 citations Open access
Semantic Scholar
BH3‐only Proteins
L. Happo, A. Strasser, C. Scott
20098 citations
Semantic Scholar
Correction to: Pharmacological blockade of Bcl-2, Bcl-xL and Bcl-w by the BH3 mimetic ABT-737 has only minor impact on tumour development in p53-deficient mice.
S. Grabow, P. Waring, L. Happo, M. Cook +3 more
2026Cell Death and Differentiation0 citations Open access
Semantic Scholar
Transforming Growth Factor-(cid:1) Directly Induces p53-up-regulated Modulator of Apoptosis (PUMA) during the Rapid Induction of Apoptosis in Myc-driven B-cell Lymphomas
L. Spender, M. Carter, Darren I. O'Brien, L. Clark +5 more
20130 citations
Semantic Scholar
The impact of BH3-only proteins on the response of murine lymphoma to anti-cancer therapy
L. Happo
20110 citations
Semantic Scholar

A. Strasser

×3

M. Herold×3

M. Carter×3

G. Smyth×2

S. Cory×2

B. Phipson×2

R. Johnstone×2

L. Spender×2