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D. Oukrif · SciRah

Researcher profile · Semantic Scholar

D. Oukrif

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D. Oukrif — researcher profile on SciRah

h-index: 29
Works: 106
Citations: 6,257

Most-cited papers

Phylogenetic ctDNA analysis depicts early stage lung cancer evolution
C. Abbosh, N. Birkbak, G. Wilson, M. Jamal-Hanjani +100 more
2017Nature1,710 citations Open access
Semantic Scholar
Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies
F. Arce Vargas, A. Furness, K. Litchfield, K. Joshi +251 more
2018Cancer Cell554 citations Open access
Semantic Scholar
Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors
F. Arce Vargas, A. Furness, I. Solomon, K. Joshi +245 more
2017Immunity386 citations Open access
Semantic Scholar
Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission.
Laura C. Greaves, S. Preston, P. Tadrous, R. Taylor +10 more
2006Proceedings of the National Academy of Sciences of the United States of America296 citations Open access
Semantic Scholar
Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study.
E. Domingo, L. Freeman-Mills, E. Rayner, M. Glaire +31 more
2016The Lancet Gastroenterology and Hepatology284 citations Open access
Semantic Scholar
Mechanisms of field cancerization in the human stomach: the expansion and spread of mutated gastric stem cells.
S. McDonald, Laura C. Greaves, L. Gutiérrez-González, M. Rodríguez-Justo +16 more
2008Gastroenterology248 citations Open access
Semantic Scholar
Clonality, founder mutations, and field cancerization in human ulcerative colitis-associated neoplasia.
S. Leedham, T. Graham, D. Oukrif, S. McDonald +6 more
2009Gastroenterology189 citations Open access
Semantic Scholar
Prognostic Impact of Novel Molecular Subtypes of Small Intestinal Neuroendocrine Tumor
A. Karpathakis, H. Dibra, C. Pipinikas, A. Feber +18 more
2015Clinical Cancer Research175 citations Open access
Semantic Scholar
Population-based study reveals new risk-stratification biomarker panel for Barrett's esophagus.
E. Bird-Lieberman, J. Dunn, H. Coleman, P. Lao-Sirieix +12 more
2011Gastroenterology164 citations
Semantic Scholar
Clonality assessment and clonal ordering of individual neoplastic crypts shows polyclonality of colorectal adenomas.
C. Thirlwell, O. Will, E. Domingo, T. Graham +12 more
2010Gastroenterology154 citations
Semantic Scholar
Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations
D. Mouradov, E. Domingo, P. Gibbs, R. Jorissen +18 more
2013American Journal of Gastroenterology141 citations Open access
Semantic Scholar
Field Cancerization in the Intestinal Epithelium of Patients With Crohn's Ileocolitis
S. Galandiuk, M. Rodríguez-Justo, R. Jeffery, A. Nicholson +7 more
2011Gastroenterology129 citations Open access
Semantic Scholar
Undifferentiated Sarcomas Develop through Distinct Evolutionary Pathways
C. Steele, M. Tarabichi, D. Oukrif, A. Webster +21 more
2019Cancer Cell115 citations Open access
Semantic Scholar
Use of multivariate analysis to suggest a new molecular classification of colorectal cancer
E. Domingo, R. Ramamoorthy, D. Oukrif, Dan Rosmarin +17 more
2013Journal of Pathology92 citations Open access
Semantic Scholar
BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer
C. López-García, Laurent Sansregret, E. Domingo, N. Mcgranahan +19 more
2017Cancer Cell91 citations Open access
Semantic Scholar
Mutation burden and other molecular markers of prognosis in colorectal cancer treated with curative intent: results from the QUASAR 2 clinical trial and an Australian community-based series
E. Domingo, C. Camps, P. Kaisaki, Marie J Parsons +25 more
2018The Lancet Gastroenterology and Hepatology68 citations Open access
Semantic Scholar
Loss of expression of the double strand break repair protein ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN
A. Beggs, E. Domingo, Megan J. Mcgregor, Mikael Presz +10 more
2012OncoTarget66 citations Open access
Semantic Scholar
Epigenetic dysregulation and poorer prognosis in DAXX-deficient pancreatic neuroendocrine tumours
C. Pipinikas, H. Dibra, A. Karpathakis, A. Feber +14 more
2015Endocrine-Related Cancer60 citations Open access
Semantic Scholar
Image cytometry accurately detects DNA ploidy abnormalities and predicts late relapse to high-grade dysplasia and adenocarcinoma in Barrett's oesophagus following photodynamic therapy
Jason M. Dunn, G. Mackenzie, D. Oukrif, C. Mosse +7 more
2010British Journal of Cancer56 citations Open access
Semantic Scholar
Tumour-infiltrating CD8+ lymphocytes and colorectal cancer recurrence by tumour and nodal stage
M. Glaire, E. Domingo, A. Sveen, J. Bruun +12 more
2019British Journal of Cancer51 citations Open access
Semantic Scholar
Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling
S. Hobor, Maise Al Bakir, C. Hiley, M. Skrzypski +291 more
2024Nature Communications49 citations Open access
Semantic Scholar
Progressive epigenetic dysregulation in neuroendocrine tumour liver metastases.
A. Karpathakis, H. Dibra, C. Pipinikas, A. Feber +17 more
2017Endocrine-Related Cancer45 citations Open access
Semantic Scholar
The development of duodenal microadenomas in FAP patients: the human correlate of the Min mouse
S. Preston, SJ Leedham, D. Oukrif, M. Deheregoda +5 more
2008Journal of Pathology42 citations Open access
Semantic Scholar
Corrigendum: Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
C. Abbosh, N. Birkbak, G. Wilson, M. Jamal-Hanjani +100 more
2017Nature40 citations Open access
Semantic Scholar
Prediction of the antibacterial activity of garlic extract on E. coli, S. aureus and B. subtilis by determining the diameter of the inhibition zones using artificial neural networks
D. Atsamnia, M. Hamadache, S. Hanini, O. Benkortbi +1 more
201737 citations Open access
Semantic Scholar
Mucosal Transcriptomics Implicates Under Expression of BRINP3 in the Pathogenesis of Ulcerative Colitis
Philip J. Smith, A. P. Levine, J. Dunne, P. Guilhamon +12 more
2014Inflammatory Bowel Diseases35 citations Open access
Semantic Scholar
Drivers underpinning the malignant transformation of giant cell tumour of bone
M. Fittall, Iben Lyskjær, P. Ellery, P. Lombard +17 more
2020medRxiv32 citations Open access
Semantic Scholar
A genetic model for central chondrosarcoma evolution correlates with patient outcome
W. Cross, Iben Lyskjær, Tom Lesluyes, S. Hargreaves +18 more
2021Genome Medicine29 citations Open access
Semantic Scholar
Comparison of nuclear texture analysis and image cytometric DNA analysis for the assessment of dysplasia in Barrett's oesophagus
J. Dunn, T. Hveem, Maria E. Pretorius, D. Oukrif +5 more
2011British Journal of Cancer25 citations Open access
Semantic Scholar
Intracellular re-localisation by photochemical internalisation enhances the cytotoxic effect of gelonin--quantitative studies in normal rat liver.
J. Woodhams, P. Lou, P. Selbo, A. Mosse +6 more
2010Journal of Controlled Release24 citations
Semantic Scholar
SH3BP4 Regulates Intestinal Stem Cells and Tumorigenesis by Modulating β-Catenin Nuclear Localization
Pedro Antas, L. Novellasdemunt, A. Kucharska, I. Massie +5 more
2019Cell Reports22 citations Open access
Semantic Scholar
Upregulation of mucin glycoprotein MUC1 in the progression to esophageal adenocarcinoma and therapeutic potential with a targeted photoactive antibody-drug conjugate
M. A. Butt, H. Pye, R. Haidry, D. Oukrif +12 more
2017OncoTarget20 citations Open access
Semantic Scholar
Image enhanced endoscopy and molecular biomarkers vs Seattle protocol to diagnose dysplasia in Barrett's esophagus.
Mathew Vithayathil, I. Modolell, J. Ortiz-Fernández-Sordo, D. Oukrif +12 more
2022Clinical Gastroenterology and Hepatology18 citations Open access
Semantic Scholar
Radiofrequency ablation is effective for the treatment of high-grade dysplasia in Barrett’s esophagus after failed photodynamic therapy
J. Dunn, M. Banks, D. Oukrif, G. Mackenzie +6 more
2011Endoscopy18 citations
Semantic Scholar
Sequential screening for lung cancer in a high-risk group: randomised controlled trial
S. Spiro, P. Shah, R. Rintoul, J. George +25 more
2019European Respiratory Journal15 citations Open access
Semantic Scholar
Using antibody directed phototherapy to target oesophageal adenocarcinoma with heterogeneous HER2 expression
H. Pye, M. A. Butt, L. Funnell, H. Reinert +17 more
2018OncoTarget13 citations Open access
Semantic Scholar
Rapid and complete paraffin removal from human tissue sections delivers enhanced Raman spectroscopic and histopathological analysis
Riana Gaifulina, D. Caruana, D. Oukrif, N. Guppy +6 more
2019In Analysis12 citations Open access
Semantic Scholar
Suppression of tumour growth from transplanted astrocytoma cells transfected with luciferase in mice by bioluminescence mediated, systemic, photodynamic therapy.
Jane Ng, Nicole A. Henríquez, N. Kitchen, N. Williams +4 more
2023Photodiagnosis and Photodynamic Therapy9 citations Open access
Semantic Scholar
NADH intraperitoneal injection prevents massive pancreatic beta cell destruction in a streptozotocin-induced diabetes in rats
Amina Abdellatif, Karima Bahria, Nada Slama, D. Oukrif +4 more
2023Histochemistry and Cell Biology8 citations
Semantic Scholar
AI-powered immune profiling from histopathology slides for chemo-radiotherapy outcome prediction in rectal cancer: a study using clinical trial and real-world cohorts
Zhuo-Yan Shen, Douglas H. Brand, Mikaël Simard, Adam P Levine +12 more
2025EBioMedicine5 citations Open access
Semantic Scholar
Tumour-infiltrating CD8+ lymphocytes as a prognostic marker in colorectal cancer: A retrospective, pooled analysis of the QUASAR2 and VICTOR trials.
M. Glaire, E. Domingo, G. Nicholson, M. Novelli +8 more
20185 citations
Semantic Scholar
Mo1134 HER2 Positivity in Metastatic Upper Gastrointestinal Tumours in a Large Multi-Centre UK Cohort Identifies Similar Positivity Rates but Different Trends Than Previously Reported and Suggests New Potential Avenues for HER2 Therapies
M. A. Butt, M. Gandy, R. Haidry, E. Bloom +9 more
20132 citations Open access
Semantic Scholar
Reliable classification of polyps based on artificial intelligence: a development and validation study
F. Julbø, Audun L. Henriksen, Manohar Pradhan, E. Lindstrøm +17 more
2026EClinicalMedicine1 citations Open access
Semantic Scholar
227 CONFOCAL LASER ENDOMICROSCOPY IN COMBINATION WITH MOLECULAR BIOMARKERS FOR THE DIAGNOSIS OF INCONSPICUOUS DYSPLASIA IN BARRETT'S ESOPHAGUS: A RANDOMISED CROSS-OVER TRIAL
Mathew Vithayathil, I. Modolell, J. O. Fernandez-sordo, D. Oukrif +11 more
20211 citations
Semantic Scholar
Comparative Therapeutic Properties of Garlic Extract and Metformin on Hyperglycaemia, Hypercholesterolaemia, and Hypertriglyceridaemia in Alloxan-induced Type1-like Diabetic Rats
D. Atsamnia, S. Hanini, D. Oukrif, K. Benachour +2 more
20161 citations
Semantic Scholar
EVALUATION OF TP53 MUTATIONS ON BARRETT'S EPITHELIUM FFPE SPECIMENS WITH A NOVEL NEXT GENERATION SEQUENCING PLATFORM HIGHLIGHTS A DISCORDANCE WITH P53 IMMUNOHISTOCHEMISTRY: ANALYSIS OF THE BARRETT'S EPITHELIUM GENOME INVESTIGATION STUDY (BEGINS)
M. A. Butt, S. Khan, R. Haidry, M. Gandy +9 more
20151 citations
Semantic Scholar
PTU-158 Dna Ploidy Abnormalities Correlate with Increasing Degree of Dysplasia in Cases Referred to a Specialist Clinical Image Cytometry Service for the Management of Barrett’S Oesophagus
D. Oukrif, M. A. Butt, E. Bloom, R. Haidry +7 more
2013Gut1 citations Open access
Semantic Scholar
PTU-157 Her2 Positivity in upper Gastrointestinal Tumours in a Large Multi-Centre UK Cohort Identifies Similar Positivity Rates but different Trends than Previously Reported and Suggests new Potential Avenues for her2 Therapies
M. A. Butt, M. Gandy, R. Haidry, E. Bloom +10 more
2013Gut1 citations Open access
Semantic Scholar
PTU-161 Expression of Polo-Like Kinase 1 and Geminin is Up-Regulated in the Squamous-Metaplasia-Dysplasia-Carcinoma Sequence and Correlates with Aneuploidy
M. A. Butt, R. Haidry, D. Oukrif, J. Dunn +9 more
2013Gut1 citations Open access
Semantic Scholar
Loss of expression of ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN
A. Beggs, E. Domingo, Megan J. Mcgregor, M. Presz +10 more
20121 citations
Semantic Scholar

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