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D. Mouradov · SciRah

Researcher profile · Semantic Scholar

D. Mouradov

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D. Mouradov — researcher profile on SciRah

h-index: 24
Works: 82
Citations: 4,270

Most-cited papers

FunRich: An open access standalone functional enrichment and interaction network analysis tool
M. Pathan, S. Keerthikumar, C. Ang, L. Gangoda +14 more
2015Proteomics1,211 citations
Semantic Scholar
Tolerance whole of genome doubling propagates chromosomal instability and accelerates cancer genome evolution
S. Dewhurst, N. Mcgranahan, R. Burrell, A. Rowan +10 more
2014Cancer Discovery414 citations Open access
Semantic Scholar
Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer.
D. Mouradov, C. Sloggett, R. Jorissen, C. Love +13 more
2014Cancer Research360 citations Open access
Semantic Scholar
SMAD2, SMAD3 and SMAD4 mutations in colorectal cancer.
N. Fleming, R. Jorissen, D. Mouradov, M. Christie +21 more
2013Cancer Research330 citations
Semantic Scholar
Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion
Neel Sengupta, C. Yau, A. Sakthianandeswaren, D. Mouradov +13 more
2013Molecular Cancer191 citations Open access
Semantic Scholar
A statistical approach for detecting genomic aberrations in heterogeneous tumor samples from single nucleotide polymorphism genotyping data
C. Yau, D. Mouradov, R. Jorissen, S. Colella +6 more
2010Genome Biology168 citations Open access
Semantic Scholar
Different APC genotypes in proximal and distal sporadic colorectal cancers suggest distinct WNT/β-catenin signalling thresholds for tumourigenesis
M. Christie, RN Jorissen, D. Mouradov, A. Sakthianandeswaren +19 more
2012Oncogene151 citations Open access
Semantic Scholar
Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations
D. Mouradov, E. Domingo, P. Gibbs, R. Jorissen +18 more
2013American Journal of Gastroenterology141 citations Open access
Semantic Scholar
PIK3CA and PTEN Gene and Exon Mutation-Specific Clinicopathologic and Molecular Associations in Colorectal Cancer
F. Day, R. Jorissen, L. Lipton, D. Mouradov +21 more
2013Clinical Cancer Research137 citations
Semantic Scholar
Onco-microbial community profiling identifies clinico-molecular and prognostic subtypes of colorectal cancer.
D. Mouradov, P. Greenfield, Shan Li, Eun-Jung In +13 more
2023Gastroenterology93 citations
Semantic Scholar
Structural basis for recruitment of tandem hotdog domains in acyl-CoA thioesterase 7 and its role in inflammation
J. Forwood, A. Thakur, G. Guncar, M. Marfori +8 more
2007Proceedings of the National Academy of Sciences of the United States of America83 citations Open access
Semantic Scholar
Translational incorporation of L‐3,4‐dihydroxyphenylalanine into proteins
K. Ozawa, M. J. Headlam, D. Mouradov, S. Watt +6 more
2005The FEBS Journal78 citations
Semantic Scholar
Lymphocytic response to tumour and deficient DNA mismatch repair identify subtypes of stage II/III colorectal cancer associated with patient outcomes
David S. Williams, D. Mouradov, R. Jorissen, M. Newman +14 more
2018Gut72 citations
Semantic Scholar
Mutation burden and other molecular markers of prognosis in colorectal cancer treated with curative intent: results from the QUASAR 2 clinical trial and an Australian community-based series
E. Domingo, C. Camps, P. Kaisaki, Marie J Parsons +25 more
2018The Lancet Gastroenterology and Hepatology68 citations Open access
Semantic Scholar
Colorectal cancer cell line proteomes are representative of primary tumors and predict drug sensitivity
Jing Wang, D. Mouradov, Xiaojing Wang, R. Jorissen +20 more
2017Gastroenterology66 citations Open access
Semantic Scholar
MACROD2 Haploinsufficiency Impairs Catalytic Activity of PARP1 and Promotes Chromosome Instability and Growth of Intestinal Tumors.
A. Sakthianandeswaren, Marie J Parsons, D. Mouradov, R. N. MacKinnon +19 more
2018Cancer Discovery49 citations
Semantic Scholar
Wild-type APC predicts poor prognosis in microsatellite-stable proximal colon cancer
R. Jorissen, M. Christie, D. Mouradov, A. Sakthianandeswaren +18 more
2015British Journal of Cancer46 citations Open access
Semantic Scholar
Low-viscosity matrix suspension culture enables scalable analysis of patient-derived organoids and tumoroids from the large intestine
Y. Hirokawa, Jordan Clarke, M. Palmieri, Tao Tan +13 more
2021Communications Biology45 citations Open access
Semantic Scholar
Unified framework for patient-derived, tumor-organoid-based predictive testing of standard-of-care therapies in metastatic colorectal cancer
Tao Tan, D. Mouradov, Margaret Lee, G. Gard +18 more
2023Cell Reports Medicine44 citations Open access
Semantic Scholar
Reprogrammed Lipid Metabolism and the Lipid-Associated Hallmarks of Colorectal Cancer
T. Salita, Y. Rustam, D. Mouradov, O. Sieber +1 more
2022Cancers43 citations Open access
Semantic Scholar
Interleukin 33 Signaling Restrains Sporadic Colon Cancer in an Interferon-γ–Dependent Manner
M. Eissmann, C. Dijkstra, Merridee A. Wouters, David Baloyan +8 more
2018Cancer immunology research38 citations Open access
Semantic Scholar
Genomic Signature of Oral Squamous Cell Carcinomas from Non-Smoking Non-Drinking Patients
K. Koo, D. Mouradov, C. Angel, T. Iseli +4 more
2021Cancers34 citations Open access
Semantic Scholar
Tumour infiltrating lymphocyte status is superior to histological grade, DNA mismatch repair and BRAF mutation for prognosis of colorectal adenocarcinomas with mucinous differentiation
David S. Williams, D. Mouradov, M. Newman, E. Amini +11 more
2020Modern Pathology27 citations Open access
Semantic Scholar
Identification of disulfide-containing chemical cross-links in proteins using MALDI-TOF/TOF-mass spectrometry.
G. King, Alun Jones, B. Kobe, T. Huber +3 more
2008Analytical Chemistry26 citations
Semantic Scholar
Relative telomere lengths in tumor and normal mucosa are related to disease progression and chromosome instability profiles in colorectal cancer
N. Suraweera, D. Mouradov, Shan Li, R. Jorissen +21 more
2016OncoTarget24 citations Open access
Semantic Scholar
Protein structure determination using a combination of cross-linking, mass spectrometry, and molecular modeling.
D. Mouradov, G. King, I. Ross, J. Forwood +5 more
2008Methods in molecular biology23 citations
Semantic Scholar
Epithelial de-differentiation triggered by co-ordinate epigenetic inactivation of the EHF and CDX1 transcription factors drives colorectal cancer progression
Ian Y Luk, Laura J Jenkins, Kael Schoffer, I. Ng +28 more
2022Cell Death and Differentiation20 citations Open access
Semantic Scholar
EHF is essential for epidermal and colonic epithelial homeostasis and suppresses Apc-initiated colonic tumorigenesis
Camilla M. Reehorst, Rebecca Nightingale, Ian Y Luk, Laura J Jenkins +14 more
2021bioRxiv20 citations Open access
Semantic Scholar
Genomic Profiling of Biliary Tract Cancer Cell Lines Reveals Molecular Subtypes and Actionable Drug Targets
David K. Lau, D. Mouradov, Wiphawan Wasenang, Ian Y Luk +17 more
2019iScience20 citations Open access
Semantic Scholar
Molecular and Cellular Pathobiology SMAD 2 , SMAD 3 and SMAD 4 Mutations in Colorectal Cancer
N. Fleming, R. Jorissen, D. Mouradov, M. Christie +21 more
201320 citations
Semantic Scholar
Modelling the structure of latexin-carboxypeptidase A complex based on chemical cross-linking and molecular docking.
D. Mouradov, A. Craven, J. Forwood, J. Flanagan +6 more
2006Protein engineering, design & selection : PEDS20 citations Open access
Semantic Scholar
Overexpression of TP53 protein is associated with the lack of adjuvant chemotherapy benefit in patients with stage III colorectal cancer
David S. Williams, D. Mouradov, Clare Browne, M. Palmieri +11 more
2019Modern Pathology18 citations Open access
Semantic Scholar
Protocol for generation of and high-throughput drug testing with patient-derived colorectal cancer organoids
Tao Tan, D. Mouradov, Peter Gibbs, O. Sieber
2024STAR Protocols17 citations Open access
Semantic Scholar
MACROD2 deletions cause impaired PARP1 activity and chromosome instability in colorectal cancer
A. Sakthianandeswaren, Marie J Parsons, D. Mouradov, O. Sieber
2018OncoTarget17 citations Open access
Semantic Scholar
Single nucleotide polymorphism array profiling identifies distinct chromosomal aberration patterns across colorectal adenomas and carcinomas
Peter Zarzour, L. Boelen, F. Luciani, D. Beck +7 more
2015Genes, Chromosomes and Cancer16 citations Open access
Semantic Scholar
CSK-homologous kinase (CHK/MATK) is a potential colorectal cancer tumour suppressor gene epigenetically silenced by promoter methylation
A. Chueh, Gahana Advani, M. Foroutan, Jai Smith +18 more
2021Oncogene15 citations Open access
Semantic Scholar
Evaluating multiple next-generation sequencing derived tumor features to accurately predict DNA mismatch repair status
Romy Walker, Peter Georgeson, Khalid Mahmood, J. Joo +22 more
2022medRxiv14 citations Open access
Semantic Scholar
Focusing the Spotlight on the Zebrafish Intestine to Illuminate Mechanisms of Colorectal Cancer.
Viola H. Lobert, D. Mouradov, J. Heath
2016Advances in Experimental Medicine and Biology14 citations
Semantic Scholar
Automated deep learning-based assessment of tumour-infiltrating lymphocyte density determines prognosis in colorectal cancer
Joshua Millward, Zhen He, A. Nibali, D. Mouradov +8 more
2025Journal of Translational Medicine13 citations Open access
Semantic Scholar
Diversity of dinoflagellate assemblages in coastal temperate and offshore tropical waters of Australia
T. Manning, Arjun Venkatesh Thilagaraj, D. Mouradov, R. Piola +4 more
2021BMC Ecology and Evolution13 citations Open access
Semantic Scholar
A Biobank of Colorectal Cancer Patient-Derived Xenografts
Suad M. Abdirahman, M. Christie, Adele Preaudet, M. Burstroem +4 more
2020Cancers13 citations Open access
Semantic Scholar
Sensory neuropeptide CGRP and its co-receptor RAMP1 drive tumour cell growth in gastrointestinal cancers
Pavitha Parathan, K. Tran, Liam Neil, Tao Tan +15 more
2025BMJ Oncology12 citations Open access
Semantic Scholar
PI3Kα Translocation Mediates Nuclear PtdIns(3,4,5)P3 Effector Signaling in Colorectal Cancer
M. Palmieri, B. Catimel, D. Mouradov, A. Sakthianandeswaren +9 more
2023Molecular & Cellular Proteomics10 citations Open access
Semantic Scholar
Proteomic and Electron Microscopy Survey of Large Assemblies in Macrophage Cytoplasm
B. Maco, I. Ross, M. Landsberg, D. Mouradov +3 more
2011Molecular & Cellular Proteomics8 citations Open access
Semantic Scholar
BCL-XL inhibitors enhance the apoptotic efficacy of BRAF inhibitors in BRAFV600E colorectal cancer
Laura J Jenkins, Ian Y Luk, F. Chionh, Tao Tan +16 more
2024Cell Death and Disease7 citations Open access
Semantic Scholar
Model systems and unique biological features of high and low-grade colorectal cancer (CRC) revealed by xenografting 84 human CRC cell lines
Ian Y Luk, J. Mooi, D. Mouradov, Tao Tan +22 more
2025Communications Biology6 citations Open access
Semantic Scholar
Adjuvant aspirin for colorectal cancer with PIK3CA-mutated and COX-2 overexpressed tumours: the ASCOLT translational research study and meta-analysis
E. Segelov, Shan Li, I. Li, D. Mouradov +16 more
2026EBioMedicine3 citations Open access
Semantic Scholar
Cross-Validation of Lipid Structure Assignment Using Orthogonal Ion Activation Modalities on the Same Mass Spectrometer.
Samuel C. Brydon, Berwyck L. J. Poad, Mengxuan Fang, Y. Rustam +7 more
2024Journal of the American Society for Mass Spectrometry3 citations Open access
Semantic Scholar
High-throughput drug screening identifies EGFR/MAPK pathway targeting sensitivities in organoid models of ovarian carcinosarcoma
Andrew Farrell, G. Dall, Cassandra J. Vandenberg, K. Shield-Artin +17 more
2026Journal of experimental & clinical cancer research : CR2 citations Open access
Semantic Scholar
Comparison between germline and somatic loss-of-function RNF43 mutations reveals different genotype-phenotype associations and provides insights into the genetic mechanisms of colorectal tumourigenesis
C. Palles, L. Freeman-Mills, E. Arbe-Barnes, Nathalie Feeley +20 more
2025Gut2 citations Open access
Semantic Scholar

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