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A. Beggs · SciRah

Researcher profile · Semantic Scholar

A. Beggs

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A. Beggs — researcher profile on SciRah

h-index: 44
Works: 316
Citations: 8,020

Most-cited papers

PIM1 controls GBP1 activity to limit self-damage and to guard against pathogen infection
Daniel Fisch, M. Pfleiderer, Eleni Anastasakou, Gillian M. Mackie +15 more
2023Science45 citations Open access
Semantic Scholar
Open Label Vancomycin in Primary Sclerosing Cholangitis-Inflammatory Bowel Disease: Improved Colonic Disease Activity and Associations With Changes in Host–Microbiome–Metabolomic Signatures
M. Quraishi, J. Cheesbrough, Peter Rimmer, B. Mullish +20 more
2024Journal of Crohn's & Colitis34 citations Open access
Semantic Scholar
Mutational signature dynamics shaping the evolution of oesophageal adenocarcinoma
Sujath Abbas, O. Pich, G. Devonshire, S. Zamani +76 more
2023Nature Communications27 citations Open access
Semantic Scholar
Mechanisms of synthetic lethality between BRCA1/2 and 53BP1 deficiencies and DNA polymerase theta targeting
George E Ronson, Katarzyna Starowicz, Elizabeth J Anthony, Ann Liza Piberger +7 more
2023Nature Communications26 citations Open access
Semantic Scholar
The empty pelvis syndrome: a core data set from the PelvEx collaborative
A. H. I. T. P. A. J. C. G. P. S. N. S. S. J. S. A. A. E. G. H. D. E. I. P. T. Mirnezami Drami Glyn Sutton Tiernan Behrenbruch Gu, A. Mirnezami, I. Drami, T. Glyn +358 more
2024British Journal of Surgery23 citations Open access
Semantic Scholar
Faecal Microbiota Transplantation [FMT] in the Treatment of Chronic Refractory Pouchitis: A Systematic Review and Meta-analysis
S. Zaman, A. Akingboye, A. Mohamedahmed, E. Peterknecht +5 more
2023Journal of Crohn's & Colitis22 citations Open access
Semantic Scholar
The Gut Microbiome, Microsatellite Status and the Response to Immunotherapy in Colorectal Cancer
T. Sillo, A. Beggs, G. Middleton, A. Akingboye
2023International Journal of Molecular Sciences20 citations Open access
Semantic Scholar
Disentangling oncogenic amplicons in esophageal adenocarcinoma
Alvin W. T. Ng, D. McClurg, Ben Wesley, S. Zamani +83 more
2024Nature Communications18 citations Open access
Semantic Scholar
Intuitive Surgical SurgToolLoc and SurgVU Challenges Results: 2022-2025
A. Zia, Max Berniker, Rogerio Nespolo, Xiao-Rui Zhang +152 more
202316 citations
Semantic Scholar
DNA reference reagents isolate biases in microbiome profiling: a global multi-lab study
Saba Anwar, Matthew Lamaudiere, Jack Hassall, Jacob Dehinsilu +100 more
2025mSystems14 citations Open access
Semantic Scholar
A population-scale temporal case–control evaluation of COVID-19 disease phenotype and related outcome rates in patients with cancer in England (UKCCP)
T. Starkey, M. Ionescu, M. Tilby, M. Little +63 more
2023Scientific Reports14 citations Open access
Semantic Scholar
Neo-adjuvant FOLFOX with and without panitumumab for patients with KRAS-wt locally advanced colon cancer: results following an extended biomarker panel on the FOxTROT Trial embedded phase II population.
J. Seligmann, D. Morton, F. Elliott, K. Handley +11 more
2025Annals of Oncology13 citations Open access
Semantic Scholar
FAecal micRobiota transplantation in primary sclerosinG chOlangitis (FARGO): study protocol for a randomised, multicentre, phase IIa, placebo-controlled trial
Sarah Al-Shakhshir, Mohammed Nabil Quraishi, B. Mullish, Arzoo M. Patel +18 more
2025BMJ Open13 citations Open access
Semantic Scholar
Circulating tumour DNA detects somatic variants contributing to spatial and temporal intra-tumoural heterogeneity in head and neck squamous cell carcinoma
K. Payne, Peter Brotherwood, Harini Suriyanarayanan, J. Brooks +5 more
2024Frontiers in Oncology13 citations Open access
Semantic Scholar
Tumour purity assessment with deep learning in colorectal cancer and impact on molecular analysis
L. Schoenpflug, A. Chatzipli, K. Sirinukunwattana, S. Richman +21 more
2024Journal of Pathology12 citations Open access
Semantic Scholar
The potential clinical utility of Whole Genome Sequencing for patients with cancer: evaluation of a regional implementation of the 100,000 Genomes Project
E. Leung, H. Robbins, S. Zaman, N. Lal +8 more
2024British Journal of Cancer11 citations Open access
Semantic Scholar
A phase II trial of mTORC1/2 inhibition in STK11 deficient non small cell lung cancer
Gary Middleton, H. Robbins, Peter Fletcher, J. Savage +19 more
2025npj Precision Oncology9 citations Open access
Semantic Scholar
MHC Class II is Induced by IFNγ and Follows Three Distinct Patterns of Expression in Colorectal Cancer Organoids
O. Pickles, K. Wanigasooriya, A. Ptasinska, A. Patel +10 more
2023Cancer Research Communications9 citations Open access
Semantic Scholar
Pancreatic Exocrine Insufficiency and the Gut Microbiome in Pancreatic Cancer: A Target for Future Diagnostic Tests and Therapies?
J. Halle-Smith, Lewis A. Hall, S. Powell-Brett, N. Merali +4 more
2023Cancers9 citations Open access
Semantic Scholar
The analysis of gut microbiota in patients with bile acid diarrhoea treated with colesevelam
Aditi Kumar, M. Quraishi, H. Al-Hassi, M. El-Asrag +8 more
2023Frontiers in Microbiology9 citations Open access
Semantic Scholar
A tumour-derived organoid biobank maps cancer gene dependencies
C. Herranz-Ors, S. Bhosle, A. Beck, J. Gilbert +85 more
2026Nature8 citations Open access
Semantic Scholar
Colon cancer biology and treatment in the era of precision oncology: A primer for Radiologists.
J. Platt, S. Pennycook, Chand E. Muthoo, A. Westwood +5 more
2025European Journal of Radiology8 citations Open access
Semantic Scholar
Involvement of the Gut Microbiome in the Local and Systemic Immune Response to Pancreatic Ductal Adenocarcinoma
J. Halle-Smith, H. Pearce, Samantha Nicol, Lewis A. Hall +5 more
2024Cancers8 citations Open access
Semantic Scholar
Major histocompatibility complex-class II is induced by Interferon-gamma and follows three distinct patterns of expression in colorectal cancer organoids
O. Pickles, K. Wanigasooriya, A. Ptasinska, A. Patel +10 more
2023Cancer Research Communications8 citations Open access
Semantic Scholar
Impaired protein hydroxylase activity causes replication stress and developmental abnormalities in humans
Sally C. Fletcher, Charlotte Hall, Tristan J. Kennedy, S. Pajusalu +21 more
2023Journal of Clinical Investigation8 citations Open access
Semantic Scholar
Multicentre validation of CT grey-level co-occurrence matrix features for overall survival in primary oesophageal adenocarcinoma
Robert O'Shea, S. Withey, K. Owczarczyk, Chris Rookyard +72 more
2024European Radiology7 citations Open access
Semantic Scholar
Risk-stratified faecal immunochemical testing (FIT) for urgent colonoscopy in Lynch syndrome during the COVID-19 pandemic
Anne G Lincoln, S. Benton, C. Piggott, Shama Sheikh +21 more
2023BJS Open7 citations Open access
Semantic Scholar
Elective surgical services need to start planning for summer pressures
M. Picciochi, J. Glasbey, Elizabeth Li, S. Kamarajah +250 more
2023British Journal of Surgery7 citations Open access
Semantic Scholar
Mechanistic insights into fecal microbiota transplantation for the treatment of ulcerative colitis: analysis of the STOP-Colitis trial
M. Quraishi, Catherine Moakes, Mehmet Yalchin, Clare Blackwell +29 more
2026Journal of Crohn's & Colitis6 citations Open access
Semantic Scholar
Hereditary gastrointestinal polyposis syndromes Rare Disease Collaborative Network consensus statement agreed at the RDCN meeting Birmingham 17th February 2022
S. Clark, V. Cuthill, Jackie Hawkins, W. Hyer +21 more
2023BJC reports6 citations Open access
Semantic Scholar
Intra-promoter switch of transcription initiation sites in proliferation signaling-dependent RNA metabolism
Joseph W. Wragg, Paige-Louise White, Yavor Hadzhiev, K. Wanigasooriya +5 more
2023Nature Structural & Molecular Biology6 citations Open access
Semantic Scholar
552O FOxTROT: Results of embedded phase II evaluating the addition of panitumumab (pan) to neo-adjuvant FOLFOX for patients (pts) with KRAS-wt colon cancer (CC) with extended biomarker panel
J. Seligmann, D. Morton, M. Seymour, F. Elliott +10 more
2023Annals of Oncology6 citations Open access
Semantic Scholar
Determining the optimal route of faecal microbiota transplant in patients with ulcerative colitis: the STOP-Colitis pilot RCT
M. Quraishi, C. Moakes, Mehmet Yalchin, Jonathan P. Segal +22 more
2024Efficacy and Mechanism Evaluation5 citations Open access
Semantic Scholar
Detection of genome-wide methylation changes in bladder cancer by long-read sequencing of urinary DNA
Anshita Goel, B. Tura, Joanne D. Stockton, N. Tovey +8 more
2025Clinical Epigenetics4 citations Open access
Semantic Scholar
TEMSET-24K: Densely Annotated Dataset for Indexing Multipart Endoscopic Videos using Surgical Timeline Segmentation
Muhammad Bilal, Mahmood Alam, D. Bapu, S. Korsgen +15 more
2025Scientific Data4 citations Open access
Semantic Scholar
A dual readout embryonic zebrafish xenograft model of rhabdomyosarcoma to assess clinically relevant multi-receptor tyrosine kinase inhibitors
Joseph W. Wragg, E. Gray, Rui Monteiro, J. Morris +3 more
2024bioRxiv4 citations Open access
Semantic Scholar
A decade of the Oesophageal Cancer Clinical and Molecular Stratification Consortium
C. J. Peters, Y. Ang, F. Ciccarelli, H. Coles +74 more
2023Nature Medicine4 citations Open access
Semantic Scholar
GRACE: protocol for a UK, secondary care, multicentre, assessor-blinded randomised controlled trial with a non-inferiority comparison to evaluate graduated compression stockings as an adjunct to extended duration pharmacological thromboprophylaxis for venous thromboembolism prevention
R. Lawton, F. Heatley, A. Beggs, T. Everington +16 more
2025BMJ Open3 citations Open access
Semantic Scholar
Identification of novel 3D-genome altering and complex structural variants underlying retinitis pigmentosa type 17 through a multistep and high-throughput approach
S. D. de Bruijn, Daan M. Panneman, N. Weisschuh, E. L. Cadena +22 more
2024Frontiers in Genetics3 citations Open access
Semantic Scholar
The FOxTROT platform: Clinical trials and exploratory research for personalization of neoadjuvant (NA) therapy in locally advanced colon cancer (LACC)—ISRCTN83842641.
C. Williams, M. White, J. Platt, J. Glasbey +13 more
2023Journal of Clinical Oncology3 citations Open access
Semantic Scholar
RAPTOR: Generative AI for Parsing Colorectal Cancer Referrals to Streamline Faster Diagnostic Standard Pathways
Sofiat Abioye, Shazad Ashraf, Junaid Qadir, Adam Byfield +11 more
2025International Conference on Medical Image Computing and Computer-Assisted Intervention2 citations
Semantic Scholar
82P Genomic alterations in biliary tract cancer and association with patient outcomes: Translational data from patients treated on the randomised phase III multicentre BILCAP clinical trial
V. E. Crolley, R. Guest, A. Beggs, E. Jaynes +5 more
2025Annals of Oncology2 citations Open access
Semantic Scholar
Repression of CADM1 transcription by HPV type 18 is mediated by three-dimensional rearrangement of promoter-enhancer interactions
Karen Campos-León, Jack Ferguson, Thomas Günther, C. D. Wood +10 more
2024bioRxiv2 citations Open access
Semantic Scholar
Investigating alterations in cancer driver genes and other potentially targetable mutations in patients with intrahepatic cholangiocarcinoma (iCCA) treated on the randomised phase III multicentre BILCAP clinical trial.
V. Crolley, R. Guest, A. Beggs, E. Jaynes +6 more
2023Journal of Clinical Oncology2 citations
Semantic Scholar
Detection of Circulating Tumour DNA (ctDNA) with ddPCR and NGS in Liposarcoma
M. Wong, M. Openshaw, M. Tarabichi, Udayaraja Gk +2 more
2026European Journal of Surgical Oncology1 citations
Semantic Scholar
Clinical utilisation and survival correlation of blood-based liquid biopsy in sarcoma - A systematic review and meta-analysis.
Chee Siong Wong, A. Rawashdeh, Anant Desai, A. Beggs
2026Surgical oncology1 citations Open access
Semantic Scholar
Detection of Circulating Tumour DNA (ctDNA) with ddPCR and NGS in Liposarcoma
M. Wong, M. Openshaw, M. Tarabichi, U. Govindasami Krishnakumari +2 more
2025European Journal of Surgical Oncology1 citations
Semantic Scholar
Abstract 4836: Re-expression of MHCII in colorectal organoids: Investigating the novel role of EHMT1 in regulating MHCII expression
Nahla Elzefzafy, Louise Tee, Maria Pinna, Neeraj Lal +2 more
2025Cancer Research1 citations
Semantic Scholar
Experimental Cancer Medicine Centre (ECMC) network proposal for a consensus gene panel for pan-cancer sequencing: a Delphi methodology
Richard J. Phillips, Bristi Basu, Z. Butt, M. Beloueche +23 more
2025British Journal of Cancer1 citations Open access
Semantic Scholar
Covered versus uncovered endoluminal stenting in the acute management of obstructing colorectal cancer in the palliative setting: randomized clinical trial (CReST2)
James Nicola Richard Kelly Manjinder Clive Hans-Ulrich A Hill Fearnhead Gray Handley Kaur Kay Laasch Lowe M, James O. Hill, N. Fearnhead, Richard Gray +418 more
2025British Journal of Surgery1 citations Open access
Semantic Scholar

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