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E. Lee · SciRah

Researcher profile · Semantic Scholar

E. Lee

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E. Lee — researcher profile on SciRah

h-index: 35
Works: 59
Citations: 9,082

Most-cited papers

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis
E. Lee, Chi-Yao Chang, Nanpin Hu, Yi-Chun J. Wang +4 more
1992Nature1,403 citations
Semantic Scholar
The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle.
D. Goodrich, Nan-Ping Wang, Yuewei Qian, E. Lee +1 more
1991Cell722 citations
Semantic Scholar
The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity
Wen-Hwa Lee, J. Shew, F. Hong, T. Sery +4 more
1987Nature623 citations
Semantic Scholar
Inactivation of the retinoblastoma susceptibility gene in human breast cancers.
E. Lee, Ho-Ang To, J. Shew, R. Bookstein +2 more
1988Science592 citations
Semantic Scholar
SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint.
Parvin T. Yazdi, Yi Wang, S. Zhao, Nimitt Patel +2 more
2002Genes & Development533 citations Open access
Semantic Scholar
Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products
S. Zhao, Yi-Chinn Weng, S. F. Yuan, Yi-Tzu Lin +10 more
2000Nature510 citations
Semantic Scholar
DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis
Gopal K. Dasika, Suh-Chin J. Lin, S. Zhao, P. Sung +2 more
1999Oncogene452 citations Open access
Semantic Scholar
The divergent Robo family protein rig-1/Robo3 is a negative regulator of slit responsiveness required for midline crossing by commissural axons.
C. Sabatier, A. Plump, Katja Brose, A. Tamada +3 more
2004Cell446 citations Open access
Semantic Scholar
Exome capture reveals ZNF423 and CEP164 mutations, linking renal ciliopathies to DNA damage response signaling
M. Chaki, Rannar Airik, A. Ghosh, R. Giles +71 more
2012Cell392 citations Open access
Semantic Scholar
Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response
Shang Li, Nicholas S. Y. Ting, Lei Zheng, Phang-Lang Chen +4 more
2000Nature341 citations
Semantic Scholar
A retinoblastoma-binding protein related to a negative regulator of Ras in yeast
Yuewei Qian, Yi-Chun J. Wang, Robert E. Jr Hollingsworth, Diane Jones +2 more
1993Nature283 citations
Semantic Scholar
Heterozygous Rb-1 delta 20/+mice are predisposed to tumors of the pituitary gland with a nearly complete penetrance.
Nanpin Hu, A. Gutsmann, D. Herbert, A. Bradley +2 more
1994Oncogene281 citations
Semantic Scholar
The retinoblastoma protein: more than a tumor suppressor.
D. Riley, E. Lee, Wen-Hwa Lee
1994Annual Review of Cell Biology230 citations
Semantic Scholar
Multiple Lineages of Human Breast Cancer Stem/Progenitor Cells Identified by Profiling with Stem Cell Markers
Wendy W. Hwang-Verslues, Wen-Hung Kuo, Po-Hao Chang, Chi Pan +9 more
2009PLoS ONE227 citations Open access
Semantic Scholar
Breast Cancer Cells Induce Cancer-Associated Fibroblasts to Secrete Hepatocyte Growth Factor to Enhance Breast Tumorigenesis
Shiaw-Wei Tyan, Wen-Hung Kuo, Chun-Kai Huang, Chi Pan +4 more
2011PLoS ONE169 citations Open access
Semantic Scholar
Activation of Robo1 signaling of breast cancer cells by Slit2 from stromal fibroblast restrains tumorigenesis via blocking PI3K/Akt/β-catenin pathway
Po-Hao Chang, Wendy W. Hwang-Verslues, Yi-Cheng Chang, Chun-Chin Chen +6 more
2012Cancer Research152 citations Open access
Semantic Scholar
Loss of corepressor PER2 under hypoxia up-regulates OCT1-mediated EMT gene expression and enhances tumor malignancy
Wendy W. Hwang-Verslues, Po-Hao Chang, Y. Jeng, Wen-Hung Kuo +13 more
2013Proceedings of the National Academy of Sciences of the United States of America150 citations Open access
Semantic Scholar
A cellular protein that competes with SV40 T antigen for binding to the retinoblastoma gene product
Shi Huang, Wen-Hwa Lee, E. Lee
1991Nature144 citations
Semantic Scholar
Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation
Bing-Nan Gu, P. Sun, Yuan-Yang Yuan, Ricardo Moraes +12 more
2009Journal of Cell Biology130 citations Open access
Semantic Scholar
Cep164 is a mediator protein required for the maintenance of genomic stability through modulation of MDC1, RPA, and CHK1.
S. Sivasubramaniam, Xue-Min Sun, Yen-Ru Pan, Shao-Hui Wang +1 more
2008Genes & Development105 citations Open access
Semantic Scholar
Ionizing radiation-induced Rad51 nuclear focus formation is cell cycle-regulated and defective in both ATM(-/-) and c-Abl(-/-) cells.
Shyng-Shiou F. Yuan, Hsueh-Ling Chang, E. Lee
2003Mutation research93 citations
Semantic Scholar
Breast Cancer Cells Induce Stromal Fibroblasts to Secrete ADAMTS1 for Cancer Invasion through an Epigenetic Change
Shiaw-Wei Tyan, Chih-Hung Hsu, Kai-Lin Peng, Chun-Chin Chen +6 more
2012PLoS ONE77 citations Open access
Semantic Scholar
Deficiency of pRb Family Proteins and p53 in Invasive Urothelial Tumorigenesis
F. He, L. Mo, Xiao-Yong Zheng, Chang-Kun Hu +4 more
2009Cancer Research76 citations Open access
Semantic Scholar
Functional analysis of FHA and BRCT domains of NBS1 in chromatin association and DNA damage responses.
S. Zhao, W. Renthal, E. Lee
2002Nucleic Acids Research74 citations Open access
Semantic Scholar
Localization and dynamic relocalization of mammalian Rad52 during the cell cycle and in response to DNA damage.
Yi-Lun Liu, Ming-jie Li, E. Lee, N. Maizels
1999Current Biology74 citations Open access
Semantic Scholar
Molecular mechanism of retinoblastoma gene inactivation in retinoblastoma cell line Y79.
E. Lee, R. Bookstein, L. Young, Chi-Jen R. Lin +2 more
1988Proceedings of the National Academy of Sciences of the United States of America66 citations Open access
Semantic Scholar
Molecular cloning of the human esterase D gene, a genetic marker of retinoblastoma.
E. Lee, WH Lee
1986Proceedings of the National Academy of Sciences of the United States of America65 citations Open access
Semantic Scholar
TGF‐β1 secreted by Tregs in lymph nodes promotes breast cancer malignancy via up‐regulation of IL‐17RB
Shih-Chia Huang, Pei-Chi Wei, Wendy W. Hwang-Verslues, Wen-Hung Kuo +7 more
2017EMBO Molecular Medicine53 citations Open access
Semantic Scholar
Glutathione peroxidase 8 negatively regulates caspase‐4/11 to protect against colitis
Jye-Lin Hsu, Jen-Wei Chou, Tzu-Fan Chen, Jeh-Ting Hsu +6 more
2019EMBO Molecular Medicine50 citations Open access
Semantic Scholar
The human checkpoint Rad protein Rad17 is chromatin-associated throughout the cell cycle, localizes to DNA replication sites, and interacts with DNA polymerase epsilon.
S. Post, A. Tomkinson, E. Lee
2003Nucleic Acids Research50 citations Open access
Semantic Scholar
UV-dependent interaction between Cep164 and XPA mediates localization of Cep164 at sites of DNA damage and UV sensitivity
Yen-Ru Pan, E. Lee
2009Cell Cycle49 citations Open access
Semantic Scholar
Nerve growth factor-induced derepression of peripherin gene expression is associated with alterations in proteins binding to a negative regulatory element
M. Thompson, E. Lee, D. Lawe, E. Gizang-Ginsberg +1 more
1992Molecular and Cellular Biology44 citations Open access
Semantic Scholar
Molecular Cloning and Developmental Expression of Mouse p130, a Member of the Retinoblastoma Gene Family (*)
Gang Chen, C. T. Guy, Hung-Wen Chen, Nanpin Hu +2 more
1996Journal of Biological Chemistry42 citations Open access
Semantic Scholar
Genes in the RB pathway and their knockout in mice.
Suh-Chin J. Lin, S. Skapek, E. Lee
1996Seminars in Cancer Biology37 citations
Semantic Scholar
Persistent expression of cyclin D1 disrupts normal photoreceptor differentiation and retina development
S. X. Skapek, Suh-Chin J. Lin, M. Jablonski, R. McKeller +3 more
2001Oncogene35 citations
Semantic Scholar
Gene deletion in urothelium by specific expression of Cre recombinase.
L. Mo, Jin Cheng, E. Lee, T. Sun +1 more
2006AJP - Renal Physiology30 citations
Semantic Scholar
ATM immunolocalization in mouse neuronal endosomes: implications for ataxia-telangiectasia.
R. Kuljiš, Gang Chen, E. Lee, M. Aguila +1 more
1999Brain Research29 citations
Semantic Scholar
Induction of Glutathione Transferase in Insulin-Like Growth Factor Type I Receptor-Overexpressed Hepatoma Cells
Jeong Yong Lee, C. Han, Jin Won Yang, Christopher Smith +4 more
2007Molecular Pharmacology28 citations Open access
Semantic Scholar
The proliferative and apoptotic activities of E2F1 in the mouse retina
Suh-Chin J. Lin, S. Skapek, D. Papermaster, M. Hankin +1 more
2001Oncogene28 citations Open access
Semantic Scholar
Tumor suppressor genes and their roles in breast cancer
L. Cox, Gang Chen, E. Lee
2004Breast Cancer Research and Treatment27 citations
Semantic Scholar
Arsenic-induced Mre11 phosphorylation is cell cycle-dependent and defective in NBS cells.
Shyng-Shiou F. Yuan, Jinu-Huang Su, Ming-Feng Hou, Fei-Wen Yang +2 more
2002DNA Repair24 citations
Semantic Scholar
Immunohistochemistry of retinoblastoma. A review.
L. Donoso, C. Shields, E. Lee
1989Ophthalmic Paediatrics and Genetics23 citations
Semantic Scholar
Breast cancer stem cells and tumor suppressor genes.
Wendy W. Hwang-Verslues, King-Jen Chang, E. Lee, Wen-Hwa Lee
2008Journal of the Formosan Medical Association = Taiwan yi zhi22 citations Open access
Semantic Scholar
Gene deletion in urothelium by specific expression of Cre recombinase
L. Mo, Jin Cheng, E. Lee, T. Sun +1 more
200521 citations
Semantic Scholar
Pax-2 interacts with RB and reverses its repression on the promoter of Rig-1, a Robo member.
Shyng-Shiou F. Yuan, Yao-Tsung Yeh, E. Lee
2002Biochemical and Biophysical Research Communications - BBRC21 citations
Semantic Scholar
Human esterase D gene: complete cDNA sequence, genomic structure, and application in the genetic diagnosis of human retinoblastoma
L. Young, E. Lee, Ho-Ang To, R. Bookstein +6 more
1988Human Genetics14 citations
Semantic Scholar
Biomarkers to Target Heterogeneous Breast Cancer Stem Cells
Wendy W. Hwang-Verslues, Wen-Hwa Lee, E. Lee
2012Journal of Molecular Biomarkers & Diagnosis13 citations Open access
Semantic Scholar
Assignment of retinoblastoma susceptibility gene to mouse chromosome 14
Chih-Lin Hsieh, Wen-Hwa Lee, E. Lee, A. M. Killary +2 more
1989Somatic Cell Genetics12 citations
Semantic Scholar
Tumor suppressor genes: a new era for molecular genetic studies of cancer
E. Lee
1991Breast Cancer Research and Treatment6 citations
Semantic Scholar
A null allele of esterase D is a marker for genetic events in retinoblastoma formation
Wen-Hwa Lee, R. Bookstein, W. Wheatley, W. Benedict +1 more
1987Human Genetics6 citations
Semantic Scholar

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