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R. Bookstein · SciRah

Researcher profile · Semantic Scholar

R. Bookstein

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R. Bookstein — researcher profile on SciRah

h-index: 33
Works: 55
Citations: 6,025

Most-cited papers

Human retinoblastoma susceptibility gene: cloning, identification, and sequence
WH Lee, R. Bookstein, F. Hong, L. Young +2 more
1987Science1,433 citations
Semantic Scholar
Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells.
H.-J. Huang, J.-K. Yee, J. Shew, P.-L. Chen +4 more
1988Science822 citations
Semantic Scholar
The retinoblastoma susceptibility gene encodes a nuclear phosphoprotein associated with DNA binding activity
Wen-Hwa Lee, J. Shew, F. Hong, T. Sery +4 more
1987Nature623 citations
Semantic Scholar
Suppression of tumorigenicity of human prostate carcinoma cells by replacing a mutated RB gene.
R. Bookstein, J. Shew, Phang-Lang Chen, P. Scully +1 more
1990Science595 citations
Semantic Scholar
Inactivation of the retinoblastoma susceptibility gene in human breast cancers.
E. Lee, Ho-Ang To, J. Shew, R. Bookstein +2 more
1988Science592 citations
Semantic Scholar
Genetic mechanisms of tumor suppression by the human p53 gene
P.-L. Chen, Y.-M. Chen, R. Bookstein, WH Lee
1990Science554 citations
Semantic Scholar
MMAC1/PTEN mutations in primary tumor specimens and tumor cell lines.
D. Teng, R. Hu, Huai-En Lin, T. Davis +24 more
1997Cancer Research494 citations
Semantic Scholar
p53 is mutated in a subset of advanced-stage prostate cancers.
R. Bookstein, D. Macgrogan, S. Hilsenbeck, F. Sharkey +1 more
1993Cancer Research399 citations
Semantic Scholar
Promoter deletion and loss of retinoblastoma gene expression in human prostate carcinoma.
R. Bookstein, P. Rio, S. A. Madreperla, F. Hong +3 more
1990Proceedings of the National Academy of Sciences of the United States of America343 citations Open access
Semantic Scholar
Development and Characterization of Recombinant Adenoviruses Encoding Human p53 for Gene Therapy of Cancer
Ken N. Wills, D. Maneval, P. Menzel, M. Harris +9 more
1994Human Gene Therapy251 citations
Semantic Scholar
Adenoviral transgene expression of MMAC/PTEN in human glioma cells inhibits Akt activation and induces anoikis.
M. Davies, Yi-Ling Lu, T. Sano, Xian-Jun Fang +8 more
1998Cancer Research246 citations
Semantic Scholar
Mutations to CCI-779 PTEN Enhanced Sensitivity of Multiple Myeloma Cells Containing Updated Version
Yi-Jiang Shi, J. Gera, Liping Hu, Jung-hsin Hsu +3 more
2002231 citations
Semantic Scholar
Comparative genomic hybridization, allelic imbalance, and fluorescence in situ hybridization on chromosome 8 in prostate cancer
M. L. Cher, D. MacGrogan, R. Bookstein, James A. Brown +2 more
1994Genes, Chromosomes and Cancer207 citations
Semantic Scholar
Suppression of tumorigenicity of glioblastoma cells by adenovirus-mediated MMAC1/PTEN gene transfer.
I. W. Cheney, Duane E. Johnson, M. Vaillancourt, Jenny B. Avanzini +7 more
1998Cancer Research197 citations
Semantic Scholar
Loss of chromosome arm 8p loci in prostate cancer: Mapping by quantitative allelic imbalance
D. MacGrogan, A. Levy, D. Bostwick, M. Wagner +2 more
1994Genes, Chromosomes and Cancer191 citations
Semantic Scholar
The Tumor Suppressor PTEN Negatively Regulates Insulin Signaling in 3T3-L1 Adipocytes*
Naoki Nakashima, Prem M. Sharma, T. Imamura, R. Bookstein +1 more
2000Journal of Biological Chemistry190 citations Open access
Semantic Scholar
Structure of the human retinoblastoma gene.
F. Hong, H. Huang, Ho-Ang To, Lih-Jiuan Young +4 more
1989Proceedings of the National Academy of Sciences of the United States of America180 citations Open access
Semantic Scholar
Comparative mutational analysis of DPC4 (Smad4) in prostatic and colorectal carcinomas
D. MacGrogan, M. Pegram, D. Slamon, R. Bookstein
1997Oncogene140 citations Open access
Semantic Scholar
Structure and methylation-associated silencing of a gene within a homozygously deleted region of human chromosome band 8p22.
Donal MacGrogan, A. Levy, G. Bova, William B. Isaacs +1 more
1996Genomics131 citations Open access
Semantic Scholar
Adenovirus-mediated gene transfer of MMAC1/PTEN to glioblastoma cells inhibits S phase entry by the recruitment of p27Kip1 into cyclin E/CDK2 complexes.
I. W. Cheney, S. Neuteboom, M. Vaillancourt, Murali Ramachandra +1 more
1999Cancer Research129 citations
Semantic Scholar
Human retinoblastoma susceptibility gene: genomic organization and analysis of heterozygous intragenic deletion mutants.
R. Bookstein, E. H. P. Lee, Ho-Ang To, Lih-Jiuan Young +4 more
1988Proceedings of the National Academy of Sciences of the United States of America117 citations Open access
Semantic Scholar
Physical mapping of chromosome 8p22 markers and their homozygous deletion in a metastatic prostate cancer.
G. Bova, D. MacGrogan, A. Levy, S. S. Pin +2 more
1996Genomics107 citations Open access
Semantic Scholar
PCR-based detection of a polymorphic BamHI site in intron 1 of the human retinoblastoma (RB) gene.
R. Bookstein, Chen-Ching Lai, Ho-Ang To, Wen-Hwa Lee
1990Nucleic Acids Research81 citations Open access
Semantic Scholar
Molecular genetics of the retinoblastoma suppressor gene.
R. Bookstein, Wen-Hwa Lee
1991Critical reviews in oncogenesis76 citations
Semantic Scholar
The product of the candidate prostate cancer susceptibility gene ELAC2 interacts with the γ‐tubulin complex
W. Korver, Claudia I. Guevara, Yang Chen, S. Neuteboom +3 more
2003International Journal of Cancer69 citations Open access
Semantic Scholar
Molecular mechanism of retinoblastoma gene inactivation in retinoblastoma cell line Y79.
E. Lee, R. Bookstein, L. Young, Chi-Jen R. Lin +2 more
1988Proceedings of the National Academy of Sciences of the United States of America66 citations Open access
Semantic Scholar
Tumour suppressor genes in prostate cancer.
Donal MacGrogan, R. Bookstein
1997Seminars in Cancer Biology63 citations Open access
Semantic Scholar
PTEN decreases in vivo vascularization of experimental gliomas in spite of proangiogenic stimuli.
T. Abe, K. Terada, H. Wakimoto, Ryo Inoue +4 more
2003Cancer Research56 citations
Semantic Scholar
Tumour-suppressor genes in prostatic oncogenesis: a positional approach.
R. Bookstein, G. Bova, Donal MacGrogan, A. Levy +1 more
1997British Journal of Urology56 citations
Semantic Scholar
p53 gene therapy in vivo of herpatocellular and liver metastatic colorectal cancer.
R. Bookstein, W. Demers, R. Gregory, D. Maneval +2 more
1996Seminars in Oncology54 citations
Semantic Scholar
The most promising surrogate endpoint biomarkers for screening candidate chemopreventive compounds for prostatic adenocarcinoma in short-term phase II clinical trials.
D. Bostwick, H. Burke, T. M. Wheeler, L. Chung +6 more
1994Journal of cellular biochemistry. Supplement53 citations
Semantic Scholar
Human retinoblastoma gene: long-range mapping and analysis of its deletion in a breast cancer cell line
R. Bookstein, E. Y. P. Lee, A. Peccei, Wen-Hwa Lee
1989Molecular and Cellular Biology53 citations Open access
Semantic Scholar
Evaluation of endostatin antiangiogenesis gene therapy in vitro and in vivo
Xiaomei Jin, R. Bookstein, K. Wills, Jenny B. Avanzini +5 more
2001Cancer Gene Therapy45 citations
Semantic Scholar
Restoration of transforming growth factor Beta signaling by functional expression of smad4 induces anoikis.
Murali Ramachandra, Isabella A. Atencio, A. Rahman, M. Vaillancourt +5 more
2002Cancer Research44 citations
Semantic Scholar
Deletion of a splice donor site ablates expression of the following exon and produces an unphosphorylated RB protein unable to bind SV40 T antigen.
J. Shew, Phang-Lang Chen, R. Bookstein, E. H. P. Lee +1 more
1990Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research44 citations
Semantic Scholar
Changes in serum enzymes, lactate, and haptoglobin following acute physical stress in international-class athletes.
P. Wolf, John A. Lott, G. Nitti, R. Bookstein
1987Clinical Biochemistry43 citations
Semantic Scholar
Tumor suppressor genes in prostatic oncogenesis.
R. Bookstein
1994Journal of cellular biochemistry. Supplement41 citations
Semantic Scholar
Intra-arterial delivery of p53-containing adenoviral vector into experimental brain tumors
T. Abe, H. Wakimoto, R. Bookstein, D. Maneval +2 more
2002Cancer Gene Therapy40 citations
Semantic Scholar
PTEN expression is maintained in sporadic colorectal tumours
K. Taniyama, S. Goodison, R. Ito, R. Bookstein +4 more
2001Journal of Pathology34 citations
Semantic Scholar
A case of synovial sarcoma with abnormal expression of the human retinoblastoma susceptibility gene.
Arturo E. Mendoza, J. Shew, E. H. P. Lee, R. Bookstein +1 more
1988Human Pathology34 citations
Semantic Scholar
High‐density screen of human tumor cell lines for homozygous deletions of loci on chromosome arm 8p
A. Levy, Uyen Dang, R. Bookstein
1999Genes, Chromosomes and Cancer33 citations
Semantic Scholar
Stability of retinoblastoma gene expression determines the tumorigenicity of reconstituted retinoblastoma cells.
Phang-Lang Chen, Yu-May Chen, Bei Shan, R. Bookstein +1 more
1992Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research33 citations
Semantic Scholar
Phenotypic analysis of human glioma cells expressing the MMAC1 tumor suppressor phosphatase
Alyssa M Morimoto, A. Berson, Gregory H. Fujii, D. Teng +4 more
1999Oncogene31 citations
Semantic Scholar
Studies on the human retinoblastoma susceptibility gene
Wen-Hwa Lee, R. Bookstein, E. H. P. Lee
1988Journal of Cellular Biochemistry29 citations
Semantic Scholar
In Vivo Tumor Suppression by Adenovirus-Mediated Interferon alpha2b Gene Delivery
C. M. Iqbal Ahmed, Barry J. Sugarman, Deba P. Saha, T. L. Nagabhushan +3 more
1999Human Gene Therapy28 citations
Semantic Scholar
Molecular biology of the human retinoblastoma gene.
W. H. Lee, R. Bookstein, E. Y. Lee
1990Immunology series22 citations
Semantic Scholar
Yeast artificial chromosome and radiation hybrid map of loci in chromosome band 8p22, a common region of allelic loss in multiple human cancers.
R. Bookstein, A. Levy, Donal MacGrogan, T. Lewis +3 more
1994Genomics21 citations
Semantic Scholar
Retinoblastoma cell lines Y79, RB355 and WERI-Rb27 are genetically related.
S. A. Madreperla, R. Bookstein, O. W. Jones, Wen-Hwa Lee
1991Ophthalmic Paediatrics and Genetics18 citations
Semantic Scholar
Recessive oncogenes.
R. Bookstein, D. Allred
1993Cancer16 citations
Semantic Scholar
Characteristics of two new retinoblastoma cell lines: WERI-Rb24 and WERI-Rb27.
T. Sery, Eva Y. Hp Lee, Wen-Hwa Lee, R. Bookstein +4 more
1990Journal of pediatric ophthalmology and strabismus16 citations
Semantic Scholar

Frequent co-authors

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Ken N. Wills×4

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M. Vaillancourt×4

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D. MacGrogan×4

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D. MacGrogan — researcher profile on SciRah

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